The Barrow Neurological Institute is proud of its reputation as a medical research facility and is home to some of the most sophisticated research programs outside of an academic setting in the Southwestern United States. Researchers in the Barrow Neurosurgery Research Center are devoted to learning more about the causes of and treatments for a wide range of disorders, such as stroke, aneurysms, spinal cord injury, and hydrocephalus. Our research has led to treatments that are being used around the world. Within the Department are neurosurgeons who subspecialize in cerebrovascular and skull base, functional and stereotactic, pediatric, spine, tumor, and endovascular neurosurgery.

Physicians, scientists, and expert clinical staff come together with a commitment to developing new techniques for the prevention, diagnosis, treatment, and rehabilitation of neurological illnesses and injuries. The leadership of internationally respected physicians keeps Barrow at the forefront of neuroscience. The compassionate expertise of its extensive staff of nurses, technologists, therapists and support personnel is evident in every aspect of care provided.

Our mission is to advance the knowledge and practice of medicine in neuroscience through basic and clinical research, education of medical professionals, and innovation in clinical techniques and technology.

Follow

Submissions from 2012

Caspase-14: A novel caspase in the retina with a potential role in diabetic retinopathy, Mohamed Al-Shabrawey, Saif Ahmad, Sylvia Megyerdi, Amira Othman, Babak Baban, Tammy L. Palenski, Eui Seok Shin, Zafer Gurel, Stephen Hsu, and Nader Sheibani

IKKα and alternative NF-κB regulate PGC-1β to promote oxidative muscle metabolism, Nadine Bakkar, Katherine Ladner, Benjamin D. Canan, Sandya Liyanarachchi, Naresh C. Bal, Meghna Pant, Muthu Periasamy, Qiutang Li, Paul M. Janssen, and Denis C. Guttridge

Link

Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities, Ines Batinic-Haberle, Ivan Spasojevic, Hubert M. Tse, Artak Tovmasyan, Zrinka Rajic, Daret K.St Clair, Zeljko Vujaskovic, Mark W. Dewhirst, and Jon D. Piganelli

Link

Erratum: Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities (Amino Acids DOI: 10.1007/s00726-010-0603-6), Ines Batinic-Haberle, Ivan Spasojevic, Hubert M. Tse, Artak Tovmasyan, Zrinka Rajic, Daret K.St Clair, Zeljko Vujaskovic, Mark W. Dewhirst, and Jon D. Piganelli

ALS untangled 15: Coconut oil, Richard Bedlack, Orla Hardiman, Tulio Bertorini, Tahseen Mozaffar, Peter Andersen, Jeff Dietz, Josep Gamez, Mazen Dimachkie, Yunxia Wang, Paul Wicks, James Heywood, Steven Novella, L. P. Rowland, Erik Pioro, Lisa Kinsley, Kathy Mitchell, Jonathan Glass, Sith Sathornsumetee, Hubert Kwiecinski, Jon Baker, Nazem Atassi, Dallas Forshew, John Ravits, Robin Conwit, Carlayne Jackson, Alex Sherman, Kate Dalton, Katherine Tindall, Ginna Gonzalez, Janice Robertson, and Larry Phillips

ALSUntangled No. 16: Cannabis, Richard Bedlack, Orla Hardiman, Tulio Bertorini, Tahseen Mozaffar, Peter Andersen, Jeff Dietz, Josep Gamez, Mazen Dimachkie, Yunxia Wang, Paul Wicks, James Heywood, Steven Novella, L. P. Rowland, Erik Pioro, Lisa Kinsley, Kathy Mitchell, Jonathan Glass, Sith Sathornsumetee, Hubert Kwiecinski, Jon Baker, Nazem Atassi, Dallas Forshew, John Ravits, Robin Conwit, Carlayne Jackson, Alex Sherman, Kate Dalton, Katherine Tindall, Ginna Gonzalez, Janice Robertson, and Larry Phillips

ALS untangled no. 17: "When ALS Is Lyme", Richard Bedlack, Orla Hardiman, Terry Heiman-Patterson, Laurie Gutmann, Mark Bromberg, Lyle Ostrow, Gregory Carter, Edor Kabashi, Tulio Bertorini, Tahseen Mozaffar, Peter Andersen, Jeff Dietz, Josep Gamez, Mazen Dimachkie, Yunxia Wang, Paul Wicks, James Heywood, Steven Novella, L. P. Rowland, Erik Pioro, Lisa Kinsley, Kathy Mitchell, Jonathan Glass, Sith Sathornsumetee, Hubert Kwiecinski, Jon Baker, Nazem Atassi, Dallas Forshew, John Ravits, Robin Conwit, and Carlayne Jackson

PDF

Structure-Activity Studies Of 7-Heteroaryl-3-Azabicyclo[3.3.1]Non-6-Enes: A Novel Class Of Highly Potent Nicotinic Receptor Ligands, Scott R. Breining, Matt Melvin, Balwinder S. Bhatti, Gary D. Byrd, Melanie N. Kiser, Christopher D. Hepler, Dawn N. Hooker, Jenny Zhang, Leslie A. Reynolds, Lisa R. Benson, Nikolai B. Fedorov, Serguei S. Sidach, J. Pike Mitchener, Linda M. Lucero, Ronald J. Lukas, Paul Whiteaker, and Daniel Yohannes

Link

Minimal homozygous endothelial deletion of eng with VEGF stimulation is sufficient to cause cerebrovascular dysplasia in the adult mouse, Eun Jung Choi, Espen J. Walker, Fanxia Shen, S. Paul Oh, Helen M. Arthur, William L. Young, and Hua Su

The Rna-Binding Motif 45 (Rbm45) Protein Accumulates In Inclusion Bodies In Amyotrophic Lateral Sclerosis (Als) And Frontotemporal Lobar Degeneration With Tdp-43 Inclusions (Ftld-Tdp) Patients, Mahlon Collins, David Riascos, Tina Kovalik, Jiyan An, Kelly Krupa, Kristin Krupa, Brian L. Hood, Thomas P. Conrads, Alan E. Renton, Bryan J. Traynor, and Robert Bowser

Cisternal sustained release dihydropyridines for subarachnoid hemorrhage, Douglas J. Cook, Sabrina Kan, Jinglu Ai, Hidetoshi Kasuya, and R. Loch Macdonald

Link

Hippocampal drebrin loss in mild cognitive impairment, Scott E. Counts, Bin He, Muhammad Nadeem, Joanne Wuu, Stephen W. Scheff, and Elliott J. Mufson

Endovascular intervention for acute stroke due to infective endocarditis: case report, Haitham Dababneh, V Shushrutha Hedna, Jenna Ford, Ziad Taimeh, Keith Peters, J Mocco, and Michael F. Waters

Modulation Of Recombinant α2* α3* Or α4*-Nicotinic Acetylcholine Receptor (Nachr) Function By Nachr β3 Subunits, Bhagirathi Dash, Minoti Bhakta, Yongchang Chang, and Ronald J. Lukas

PDF

Modulation Of Gain-Of-Function α6*-Nicotinic Acetylcholine Receptor By β3 Subunits, Bhagirathi Dash and Ronald J. Lukas

GM1485, a nonimmunosuppressive immunophilin ligand, promotes neurofunctional improvement and neural regeneration following stroke, Andrew F. Ducruet, Peter A. DeRosa, Brad E. Zacharia, Sergey A. Sosunov, E Sander Connolly, and David E. Weinstein

The surgical management of chronic subdural hematoma, Andrew F. Ducruet, Bartosz T. Grobelny, Brad E. Zacharia, Zachary L. Hickman, Peter L. DeRosa, Kristen N. Andersen, Kristen Anderson, Eric Sussman, Austin Carpenter, and E Sander Connolly

Complement inhibition promotes endogenous neurogenesis and sustained anti-inflammatory neuroprotection following reperfused stroke, Andrew F. Ducruet, Brad E. Zacharia, Sergey A. Sosunov, Paul R. Gigante, Mason L. Yeh, Justin W. Gorski, Marc L. Otten, Richard Y. Hwang, Peter A. DeRosa, Zachary L. Hickman, Paulina Sergot, and E Sander Connolly

Associations between hepatocyte growth factor, c-Met, and basic fibroblast growth factor and survival in endometrial cancer patients, A. S. Felix, R. P. Edwards, R. A. Stone, M. Chivukula, A. V. Parwani, R. Bowser, F. Linkov, and J. L. Weissfeld

Survival outcomes in endometrial cancer patients are associated with CXCL12 and estrogen receptor expression, Ashley S. Felix, Roslyn A. Stone, Mamatha Chivukula, Robert Bowser, Anil V. Parwani, Faina Linkov, Robert P. Edwards, and Joel L. Weissfeld

Effect of long-term exposure to lower low-density lipoprotein cholesterol beginning early in life on the risk of coronary heart disease: A mendelian randomization analysis, Brian A. Ference, Wonsuk Yoo, Issa Alesh, Nitin Mahajan, Karolina K. Mirowska, Abhishek Mewada, Joel Kahn, Luis Afonso, Kim Allan Williams, and John M. Flack

Link

Progranulin gene variability and plasma levels in bipolar disorder and schizophrenia, Daniela Galimberti, Bernardo Dell'Osso, Chiara Fenoglio, Chiara Villa, Francesca Cortini, Maria Serpente, Sarah Kittel-Schneider, Johannes Weigl, Maria Neuner, Juliane Volkert, C Leonhard, David G. Olmes, Juliane Kopf, Claudia Cantoni, Elisa Ridolfi, Carlotta Palazzo, Laura Ghezzi, Nereo Bresolin, A C. Altamura, Elio Scarpini, and Andreas Reif

PDF

Function Of Human α3β4α5 Nicotinic Acetylcholine Receptors Is Reduced By The β5(D398N) Variant, Andrew A. George, Linda M. Lucero, M. Imad Damaj, Ronald J. Lukas, Xiangning Chen, and Paul Whiteaker

Link

Three-dimensional architecture of the rod sensory cilium and its disruption in retinal neurodegeneration, Jared C. Gilliam, Juan T. Chang, Ivette M. Sandoval, Youwen Zhang, Tiansen Li, Steven J. Pittler, Wah Chiu, and Theodore G. Wensel

Link

Striatal pleiotrophin overexpression provides functional and morphological neuroprotection in the 6-hydroxydopamine model, Sara E. Gombash, Jack W. Lipton, Timothy J. Collier, Lalitha Madhavan, Kathy Steece-Collier, Allyson Cole-Strauss, Brian T. Terpstra, Anne L. Spieles-Engemann, Brian F. Daley, Susan L. Wohlgenant, Valerie B. Thompson, Fredric P. Manfredsson, Ronald J. Mandel, and Caryl E. Sortwell

Link

Gastric angiodysplasia in a hereditary hemorrhagic telangiectasia type 2 patient, Minsu Ha, Yoon Jae Kim, Kwang An Kwon, Ki Baik Hahm, Mi Jung Kim, Dong Kyu Kim, Young Jae Lee, and S. Paul Oh

Link

Early change in ferumoxytol-enhanced magnetic resonance imaging signal suggests unstable human cerebral aneurysm: A pilot study, David Hasan, Nohra Chalouhi, Pascal Jabbour, Aaron S. Dumont, David K. Kung, Vincent A. Magnotta, William L. Young, Tomoki Hashimoto, H. Richard Winn, and Donald Heistad

Link

Macrophage imbalance (M1 vs. M2) and upregulation of mast cells in wall of ruptured human cerebral aneurysms: preliminary results, David Hasan, Nohra Chalouhi, Pascal Jabbour, and Tomoki Hashimoto

Link

Upregulation of cyclooxygenase-2 (COX-2) and microsomal prostaglandin E2 synthase-1 (mPGES-1) in wall of ruptured human cerebral aneurysms: preliminary results, David Hasan, Tomoki Hashimoto, David Kung, R Loch Macdonald, H Richard Winn, and Donald Heistad

Trends in the management of atrial fibrillation: A neurologist's perspective, Vishnumurthy Shushrutha Hedna, Christopher G. Favilla, Waldo R. Guerrero, Akhil Patel, Amareshwari Gottipati, Sharathchandra Bidari, Thomas Beaver, and Michael F. Waters

Takayasu's arteritis: Is it a reversible disease? Case Report and Literature Review, Vishnumurthy Shushrutha Hedna, Akhil Patel, Sharathchandra Bidari, Melissa Elder, Brian L. Hoh, Anthony Yachnis, and Michael F. Waters

Seizure Mimicking Stroke: Role of CT Perfusion, Vishnumurthy Shushrutha Hedna, Prerak P. Shukla, and Michael F. Waters

Posterior reversible encephalopathy syndrome (PRES) and CT perfusion changes, Vishnumurthy Shushrutha Hedna, Latha Ganti Stead, Sharathchandra Bidari, Akhil Patel, Amareshwari Gottipati, Christopher G. Favilla, Arash Salardini, Aunali Khaku, Diana Mora, Ajay Pandey, Het Patel, and Michael F. Waters

Genetic Deletion Of Tnf Receptor Suppresses Excitatory Synaptic Transmission Via Reducing Ampa Receptor Synaptic Localization In Cortical Neurons, Ping He, Qiang Liu, Jie Wu, and Yong Shen

Evaluation of intraventricular hemorrhage assessment methods for predicting outcome following intracerebral hemorrhage, Brian Y. Hwang, Samuel S. Bruce, Geoffrey Appelboom, Matthew A. Piazza, Amanda M. Carpenter, Paul R. Gigante, Christopher P. Kellner, Andrew F. Ducruet, Michael A. Kellner, Rajeev Deb-Sen, Kerry A. Vaughan, Philip M. Meyers, and E Sander Connolly

Link

Loss of functional alpha-synuclein: A toxic event in Parkinson's disease?, Nicholas M. Kanaan and Fredric P. Manfredsson

Neuroprotective efficacy of Nardostachys jatamansi and crocetin in conjunction with selenium in cognitive impairment, M. Badruzzaman Khan, Md Nasrul Hoda, Tauheed Ishrat, Saif Ahmad, Mohd Moshahid Khan, Ajmal Ahmad, Seema Yusuf, and Fakhrul Islam

PDF

Acute Exposure To The Mitochondrial Complex I Toxin Rotenone Impairs Synaptic Long-Term Potentiation In Rat Hippocampal Slices, Ryoichi Kimura, Lu Yao Ma, Chen Wu, Dharshaun Turner, Jian Xin Shen, Kevin Ellsworth, Makoto Wakui, Marwan Maalouf, and Jie Wu

Regulation of XFGF8 gene expression through SRY (sex-determining region Y)-box 2 in developing Xenopus embryos., Yong Hwan Kim, Jee Yoon Shin, Wonho Na, Jungho Kim, Bong-Gun Ju, and Won-Sun Kim

Retinoid Signaling Alterations In Amyotrophic Lateral Sclerosis, Christi L. Kolarcik and Robert Bowser

Biochemical alterations associated with ALS, Kay A. Lawton, Merit E. Cudkowicz, Meredith V. Brown, Danny Alexander, Rebecca Caffrey, Jacob E. Wulff, Robert Bowser, Robert Lawson, Matt Jaffa, Michael V. Milburn, John A. Ryals, and James D. Berry

PDF

A Pilot Trial Of Pioglitazone Hcl And Tretinoin In Als: Cerebrospinal Fluid Biomarkers To Monitor Drug Efficacy And Predict Rate Of Disease Progression, Todd D. Levine, Robert Bowser, Nicole C. Hank, Stephen Gately, Dietrich Stephan, David S. Saperstein, and Kendall Van Keuren-Jensen

PDF

Functional α7β2 Nicotinic Acetylcholine Receptors Expressed In Hippocampal Interneurons Exhibit High Sensitivity To Pathological Level Of Amyloid β Peptides, Qiang Liu, Yao Huang, Jianxin Shen, Scott Steffensen, and Jie Wu

The Role Of Androgen-Induced Growth Factor (Fgf8) On Genital Tubercle Development In A Hypospadiac Male Rat Model Of Prenatal Exposure To Di-N-Butyl Phthalate, Shi Bo Liu, Zheng Ma, Wen Lan Sun, Xiao Wen Sun, Yan Hong, Long Ma, Chao Qin, Harrison J. Stratton, Qiang Liu, and Jun Tao Jiang

α7 Nicotinic Acetylcholine Receptor-Mediated Neuroprotection Against Dopaminergic Neuron Loss In An Mptp Mouse Model Via Inhibition Of Astrocyte Activation, Yuan Liu, Jun Hu, Jie Wu, Chenlei Zhu, Yujian Hui, Yaping Han, Zuhu Huang, Kevin Ellsworth, and Weimin Fan

Vitamin B12 deficiency associated with concomitant metformin and proton pump inhibitor use, Amanda N. Long, Christopher L. Atwell, Wonsuk Yoo, and Solomon S. Solomon

Identification Of Novel Splice Variants And Exons Of Human Endothelial Cell-Specific Chemotaxic Regulator (Ecscr) By Bioinformatics Analysis, Jia Lu, Chaokun Li, Chunwei Shi, James Balducci, Hanju Huang, Hong Long Ji, Yongchang Chang, and Yao Huang

Lifelong rapamycin administration ameliorates age-dependent cognitive deficits by reducing IL-1β and enhancing NMDA signaling, Smita Majumder, Antonella Caccamo, David X. Medina, Adriana D. Benavides, Martin A. Javors, Ellen Kraig, Randy Strong, Arlan Richardson, and Salvatore Oddo

Link

Pharmacological stabilization of intracranial aneurysms in mice: a feasibility study, Hiroshi Makino, Yoshiteru Tada, Kosuke Wada, Elena I. Liang, Mayland Chang, Shahriar Mobashery, Yasuhisa Kanematsu, Chie Kurihara, Emma Palova, Miyuki Kanematsu, Keiko Kitazato, and Tomoki Hashimoto

Pesticide Exposure As A Risk Factor For Amyotrophic Lateral Sclerosis: A Meta-Analysis Of Epidemiological Studies. Pesticide Exposure As A Risk Factor For Als., Angela M. Malek, Aaron Barchowsky, Robert Bowser, Ada Youk, and Evelyn O. Talbott

Link

Regulated protein expression for in vivo gene therapy for neurological disorders: Progress, strategies, and issues, Fredric P. Manfredsson, David C. Bloom, and Ronald J. Mandel

Link

MicroRNA and mRNA expression profile screening in multiple sclerosis patients to unravel novel pathogenic steps and identify potential biomarkers, Filippo Martinelli-Boneschi, Chiara Fenoglio, Paola Brambilla, Melissa Sorosina, Giacomo Giacalone, Federica Esposito, Maria Serpente, Claudia Cantoni, Elisa Ridolfi, Mariaemma Rodegher, Lucia Moiola, Bruno Colombo, Milena De Riz, Vittorio Martinelli, Elio Scarpini, Giancarlo Comi, and Daniela Galimberti

Reference Measurement Procedures For Alzheimers Disease Cerebrospinal Fluid Biomarkers: Definitions And Approaches With Focus On Amyloid 42, Niklas Mattsson, Ingrid Zegers, Ulf Andreasson, Maria Bjerke, Marinus A. Blankenstein, Robert Bowser, Maria C. Carrillo, Johan Gobom, Theresa Heath, R Jenkins, Andreas Jeromin, June Kaplow, Daniel Kidd, Omar F. Laterza, Andrew Lockhart, Michael P. Lunn, Robert L. Martone, Kevin Mills, Josef Pannee, Marianne Ratcliffe, Leslie M. Shaw, Adam J. Simon, Holly Soares, Charlotte E. Teunissen, Marcel M. Verbeek, Robert M. Umek, Hugo Vanderstichele, Henrik Zetterberg, Kaj Blennow, and Erik Portelius

A Novel α-Conotoxin Mii-Sensitive Nicotinic Acetylcholine Receptor Modulates [ 3H]-Gaba Release In The Superficial Layers Of The Mouse Superior Colliculus, Tristan D. McClure-Begley, Charles R. Wageman, Sharon R. Grady, Michael J. Marks, J. Michael McIntosh, Allan C. Collins, and Paul Whiteaker

Link

Separated at birth? the functional and molecular divergence of OLIG1 and OLIG2, Dimphna H. Meijer, Michael F. Kane, Shwetal Mehta, Hongye Liu, Emily Harrington, Christopher M. Taylor, Charles D. Stiles, and David H. Rowitch

Link

Manganese superoxide dismutase, MnSOD and its mimics, Sumitra Miriyala, Ivan Spasojevic, Artak Tovmasyan, Daniela Salvemini, Zeljko Vujaskovic, Daret St. Clair, and Ines Batinic-Haberle

Link

Mn porphyrins as novel molecular magnetic resonance imaging contrast agents, Vladimir Mouraviev, Talaignair N. Venkatraman, Artak Tovmasyan, Masaki Kimura, Matvey Tsivian, Vladimira Mouravieva, Tom J. Polascik, Haichen Wang, Timothy J. Amrhein, Ines Batinic-Haberle, and Christopher Lascola

Link

Mild cognitive impairment: Pathology and mechanisms, Elliott J. Mufson, Lester Binder, Scott E. Counts, Steven T. Dekosky, Leyla Detoledo-Morrell, Stephen D. Ginsberg, Milos D. Ikonomovic, Sylvia E. Perez, and Stephen W. Scheff

Link

Hippocampal ProNGF signaling pathways and β-amyloid levels in mild cognitive impairment and alzheimer disease, Elliott J. Mufson, Bin He, Muhammad Nadeem, Sylvia E. Perez, Scott E. Counts, Sue Leurgans, Jason Fritz, James Lah, Stephen D. Ginsberg, Joanne Wuu, and Stephen W. Scheff

α7β2 Nicotinic Acetylcholine Receptors Assemble Function And Are Activated Primarily Via Their α7-α7 Interfaces, Teresa A. Murray, Daniel Bertrand, Roger L. Papke, Andrew A. George, Rigo Pantoja, Rahul Srinivasan, Qiang Liu, Jie Wu, Paul Whiteaker, Henry A. Lester, and Ronald J. Lukas

Roadmap And Standard Operating Procedures For Biobanking And Discovery Of Neurochemical Markers In Als, Markus Otto, Robert Bowser, Martin Turner, James Berry, Johannes Brettschneider, James Connor, Jlia Costa, Merit Cudkowicz, Jonathan Glass, Olaf Jahn, Stefan Lehnert, Andrea Malaspina, Lucilla Parnetti, Axel Petzold, Pamela Shaw, Alexander Sherman, Petra Steinacker, Sigurd Sßmuth, Charlotte Teunissen, Hayrettin Tumani, Anna Wuolikainen, and Albert Ludolph

Link

Effects of aromatase inhibition versus gonadectomy on hippocampal complex amyloid pathology in triple transgenic mice, Cassia R. Overk, Pei Yi Lu, Yue Ting Wang, Jaewoo Choi, James W. Shaw, Gregory R. Thatcher, and Elliott J. Mufson

Neuroprotection For Amyotrophic Lateral Sclerosis: Role Of Stem Cells Growth Factors And Gene Therapy, Rachna S. Pandya, Lilly L.J. Mao, Edward W. Zhou, Robert Bowser, Zhenglun Zhu, Yongjin Zhu, and Xin Wang

Link

Rac1b increases with progressive tau pathology within cholinergic nucleus basalis neurons in alzheimer's disease, Sylvia E. Perez, Damianka P. Getova, Bin He, Scott E. Counts, Changiz Geula, Laurent Desire, Severine Coutadeur, Helene Peillon, Stephen D. Ginsberg, and Elliott J. Mufson

Dimebon alters hippocampal amyloid pathology in 3xTg-AD mice, Sylvia E. Perez, Muhammad Nadeem, Katherine R. Sadleir, Joanna Matras, Christy M. Kelley, Scott E. Counts, Robert Vassar, and Elliott J. Mufson

Rhodopsin gene expression determines rod outer segment size and rod cell resistance to a dominant-negative neurodegeneration mutant, Brandee A. Price, Ivette M. Sandoval, Fung Chan, Ralph Nichols, Ramon Roman-Sanchez, Theodore G. Wensel, and John H. Wilson

A new SOD mimic, Mn(III) ortho N-butoxyethylpyridylporphyrin, combines superb potency and lipophilicity with low toxicity, Zrinka Rajic, Artak Tovmasyan, Ivan Spasojevic, Huaxin Sheng, Miaomiao Lu, Alice M. Li, Edith B. Gralla, David S. Warner, Ludmil Benov, and Ines Batinic-Haberle

BDNF may play a differential role in the protective effect of the mGluR2/3 agonist LY379268 on striatal projection neurons in R6/2 Huntington's disease mice, A. Reiner, H. B. Wang, N. Del Mar, K. Sakata, W. Yoo, and Y. P. Deng

Biomechanical analysis of a novel hook-screw technique for C1-2 stabilization: Technical note, Marco Túlio Reis, Eric W. Nottmeier, Phillip M. Reyes, Seungwon Baek, and Neil R. Crawford

Mechanisms of microthrombi formation after experimental subarachnoid hemorrhage, M. Sabri, J. Ai, K. Lakovic, J. D'abbondanza, D. Ilodigwe, and R. L. MacDonald

Link

Neuronal LR11 expression does not differentiate between clinically-defined Alzheimer's disease and control brains, Kristen L. Sager, Joanne Wuu, Jeremy H. Herskowitz, Elliott J. Mufson, Allan I. Levey, and James J. Lah

Advanced technical skills are required for microsurgical clipping of posterior communicating artery aneurysms in the endovascular era., Nader Sanai, Nolan Caldwell, Dario J Englot, and Michael T Lawton

Link

Characterization of restricted diffusion in uni- and multi-lamellar vesicles using short distance iMQCs, A. M. Stokes, J. W. Wilson, and W. S. Warren

Regulated temporal-spatial astrocyte precursor cell proliferation involves BRAF signalling in mammalian spinal cord, An-Chi Tien, Hui-Hsin Tsai, Anna V. Molofsky, Martin McMahon, Lynette C. Foo, Aparna Kaul, Joseph D. Dougherty, Nathaniel Heintz, David H. Gutmann, Ben A. Barres, and David H. Rowitch

Computed tomographic perfusion imaging of non-hemorrhagic cerebral hyperperfusion syndrome and reversal following medical treatment after carotid artery angioplasty and stenting, Raul A. Vasquez, Michael F. Waters, Christopher J. Skowlund, J Mocco, and Brian L. Hoh

Direct thrombectomy using the Penumbra thromboaspiration catheter for the treatment of cerebral venous sinus thrombosis, Gregory J. Velat, Christopher J. Skowlund, Michael F. Waters, J Mocco, and Brian L. Hoh

Differential Contributions Of Somatic And Dendritic Calcium-Dependent Potassium Currents To The Control Of Motoneuron Excitability Following Spinal Cord Injury, Sharmila Venugopal, Thomas M. Hamm, and Ranu Jung

Link

Genetics and expression analysis of the specificity protein 4 gene (SP4) in patients with Alzheimer's disease and frontotemporal lobar degeneration, Chiara Villa, Laura Ghezzi, Chiara Fenoglio, Francesca Clerici, Alessandra Marcone, Luisa Benussi, Roberta Ghidoni, Salvatore Gallone, Maria Serpente, Claudia Cantoni, Elisa Ridolfi, Rossana Bonsi, Chiara Cerami, Stefano Cappa, Giuliano Binetti, Massimo Franceschi, Innocenzo Rainero, Claudio Mariani, Nereo Bresolin, Elio Scarpini, and Daniela Galimberti

Mapping Single-Cell-Substrate Interactions By Surface Plasmon Resonance Microscopy, Wei Wang, Shaopeng Wang, Qiang Liu, Jie Wu, and Nongjian Tao

Label-Free Measuring And Mapping Of Binding Kinetics Of Membrane Proteins In Single Living Cells, Wei Wang, Yunze Yang, Shaopeng Wang, Vinay J. Nagaraj, Qiang Liu, Jie Wu, and Nongjian Tao

Oculomotor and visual axis systems sparing in spinocerebellar ataxia type 13(R420H), Michael F. Waters, Sankarasubramoney H. Subramony, Joel Advincula, Susan Perlman, and Tetsuo Ashizawa

PDF

Structural And Functional Characterization Of Two Alternative Splicing Variants Of Mouse Endothelial Cell-Specific Chemotaxis Regulator (Ecscr), Wen Wu, Chunwei Shi, Fanxin Ma, James Balducci, Hanju Huang, Hong Long Ji, Yongchang Chang, and Yao Huang

Link

Rapamycin induces glucose intolerance in mice by reducing islet mass, insulin content, and insulin sensitivity, Shi Bing Yang, Hye Young Lee, David Matthew Young, An Chi Tien, Ashley Rowson-Baldwin, Yu Yu Shu, Yuh Nung Jan, and Lily Yeh Jan

Link

Rapamycin ameliorates age-dependent obesity associated with increased mTOR signaling in hypothalamic POMC neurons, Shi Bing Yang, An Chi Tien, Gayatri Boddupalli, Allison W. Xu, Yuh Nung Jan, and Lily Yeh Jan

PDF

Discovery Of Highly Potent And Selective α4β2-Nicotinic Acetylcholine Receptor (Nachr) Partial Agonists Containing An Isoxazolylpyridine Ether Scaffold That Demonstrate Antidepressant-Like Activity. Part II, Li Fang Yu, J. Brek Eaton, Allison Fedolak, Han Kun Zhang, Taleen Hanania, Dani Brunner, Ronald J. Lukas, and Alan P. Kozikowski

PDF

Identification Of Novel α4β2-Nicotinic Acetylcholine Receptor (Nachr) Agonists Based On An Isoxazole Ether Scaffold That Demonstrate Antidepressant-Like Activity, Li Fang Yu, Werner Tuckmantel, J. Brek Eaton, Barbara Caldarone, Allison Fedolak, Taleen Hanania, Dani Brunner, Ronald J. Lukas, and Alan P. Kozikowski

Epidemiological trends in the neurological intensive care unit from 2000 to 2008, Brad E. Zacharia, Kerry A. Vaughan, Samuel S. Bruce, Bartosz T. Grobelny, Reshma Narula, Joyce Khandji, Amanda M. Carpenter, Zachary L. Hickman, Andrew F. Ducruet, and E Sander Connolly

Impact Of Prefrontal Cortex In Nicotine-Induced Excitation Of Ventral Tegmental Area Dopamine Neurons In Anesthetized Rats, Die Zhang, Ming Gao, Dan Xu, Wei Xing Shi, Boris S. Gutkin, Scott C. Steffensen, Ronald J. Lukas, and Jie Wu

PDF

Insights Into The Structural Determinants Required For High-Affinity Binding Of Chiral Cyclopropane-Containing Ligands To α4β2-Nicotinic Acetylcholine Receptors: An Integrated Approach To Behaviorally Active Nicotinic Ligands, Han Kun Zhang, J. Brek Eaton, Li Fang Yu, Mieke Nys, Angelica Mazzolari, Rene Van Elk, August B. Smit, Vadim Alexandrov, Taleen Hanania, Emily Sabath, Allison Fedolak, Daniela Brunner, Ronald J. Lukas, Giulio Vistoli, Chris Ulens, and Alan P. Kozikowski

PDF

Chemistry And Behavioral Studies Identify Chiral Cyclopropanes As Selective α4β2-Nicotinic Acetylcholine Receptor Partial Agonists Exhibiting An Antidepressant Profile, Hankun Zhang, Werner Tuckmantel, J. Brek Eaton, Po Wai Yuen, Li Fang Yu, Krishna Mohan Bajjuri, Allison Fedolak, Daguang Wang, Afshin Ghavami, Barbara Caldarone, Neil E. Paterson, David A. Lowe, Daniela Brunner, and Ronald J. Lukas

Characterization Of A Novel Splice Variant Of δ Enac Subunit In Human Lungs, Run Zhen Zhao, Hong Guang Nie, Xue Feng Su, Dong Yun Han, Andrew Lee, Yao Huang, Yongchang Chang, Sadis Matalon, and Hong Long Ji

Pharmacologic reduction of angiographic vasospasm in experimental subarachnoid hemorrhage: Systematic review and meta-analysis, Tommaso Zoerle, Don C. Ilodigwe, Hoyee Wan, Katarina Lakovic, Mohammed Sabri, Jinglu Ai, and R. Loch MacDonald

Submissions from 2011

Genetic and functional studies of a missense variant in a glutamate transporter, SLC1A3, in Tourette syndrome, Abby Adamczyk, Colin D. Gause, Rita Sattler, Svetlana Vidensky, Jeffery D. Rothstein, Harvey Singer, and Tao Wang

Link

Continuous cardiac output measurement with a Doppler-equipped pulmonary artery catheter, Shigeru Akamatsu, Yuji Kondo, Norio Ueda, Akiko Kojima, Naokazu Fukuoka, Motoshi Takada, Shuji Dohi, and Tomoki Hashimoto

Intranasal delivery of caspase-9 inhibitor reduces caspase-6-dependent axon/neuron loss and improves neurological function after stroke, Nsikan Akpan, Esther Serrano-Saiz, Brad E. Zacharia, Marc L. Otten, Andrew F. Ducruet, Scott J. Snipas, Wen Liu, Jennifer Velloza, Greg Cohen, Sergeyi A. Sosunov, William H. Frey, Guy S. Salvesen, E Sander Connolly, and Carol M. Troy

Impact of intracranial self-expanding stents in the treatment of acute ischemic stroke: efficacy and limitations, Saeed Ansari, Douglas J. McConnell, Hassan Azari, Elad I. Levy, Brian L. Hoh, Michael F. Waters, and J Mocco

Intracranial stents for treatment of acute ischemic stroke: evolution and current status, Saeed Ansari, Douglas J. McConnell, Gregory J. Velat, Michael F. Waters, Elad I. Levy, Brian L. Hoh, and J Mocco

Recanalization therapy for acute ischemic stroke, part 2: mechanical intra-arterial technologies, Saeed Ansari, Maryam Rahman, Douglas J. McConnell, Michael F. Waters, Brian L. Hoh, and J Mocco

Recanalization therapy for acute ischemic stroke, part 1: surgical embolectomy and chemical thrombolysis, Saeed Ansari, Maryam Rahman, Michael F. Waters, Brian L. Hoh, and J Mocco

Biomechanical advantage of the index-level pedicle screw in unstable thoracolumbar junction fractures: Presented at the 2010 Joint Spine Section Meeting - Laboratory investigation, Ali A. Baaj, Phillip M. Reyes, Ali S. Yaqoobi, Juan S. Uribe, Fernando L. Vale, Nicholas Theodore, Volker K.H. Sonntag, and Neil R. Crawford