The Barrow Neurological Institute is proud of its reputation as a medical research facility and is home to some of the most sophisticated research programs outside of an academic setting in the Southwestern United States. Researchers in the Barrow Neurosurgery Research Center are devoted to learning more about the causes of and treatments for a wide range of disorders, such as stroke, aneurysms, spinal cord injury, and hydrocephalus. Our research has led to treatments that are being used around the world. Within the Department are neurosurgeons who subspecialize in cerebrovascular and skull base, functional and stereotactic, pediatric, spine, tumor, and endovascular neurosurgery.

Physicians, scientists, and expert clinical staff come together with a commitment to developing new techniques for the prevention, diagnosis, treatment, and rehabilitation of neurological illnesses and injuries. The leadership of internationally respected physicians keeps Barrow at the forefront of neuroscience. The compassionate expertise of its extensive staff of nurses, technologists, therapists and support personnel is evident in every aspect of care provided.

Our mission is to advance the knowledge and practice of medicine in neuroscience through basic and clinical research, education of medical professionals, and innovation in clinical techniques and technology.

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Submissions from 2015

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Activation Of α7 Nicotinic Acetylcholine Receptors Prevents Monosodium Iodoacetate-Induced Osteoarthritis In Rats, Yuan Liu, Dongying Wu, Fanglong Song, Chenlei Zhu, Yujian Hui, Qingcheng Zhu, Jie Wu, Weimin Fan, and Jun Hu

Activation Of α7 Nicotinic Acetylcholine Receptors Protects Astrocytes Against Oxidative Stress-Induced Apoptosis: Implications For Parkinson'S Disease, Yuan Liu, Xiaoning Zeng, Yujian Hui, Chenlei Zhu, Jie Wu, Devin H. Taylor, Juan Ji, Weimin Fan, Zuhu Huang, and Jun Hu

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Rbm45 Homo-Oligomerization Mediates Association With Als-Linked Proteins And Stress Granules, Yang Li, Mahlon Collins, Rachel Geiser, Nadine Bakkar, David Riascos, and Robert Bowser

A comprehensive library of familial human amyotrophic lateral sclerosis induced pluripotent stem cells, Ying Li, Umamahesw Balasubramanian, Devon Cohen, Ping-Wu Zhang, Elizabeth Mosmiller, Rita Sattler, Nicholas J. Maragakis, and Jeffrey D. Rothstein

Association of Circulating Follicular Helper T Cells With Disease Course of NMO Spectrum Disorders, Yu Jing Li, Fang Zhang, Yuan Qi, Guo Qiang Chang, Ying Fu, Lei Su, Yi Shen, Na Sun, Aimee Borazanci, Chunsheng Yang, Fu-Dong Shi, and Yaping Yan

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Successful serial imaging of the mouse cerebral arteries using conventional 3-T magnetic resonance imaging, Hiroshi Makino, Kazuya Hokamura, Takahiro Natsume, Tetsuro Kimura, Yoshinobu Kamio, Yasuhiro Magata, Hiroki Namba, Takasumi Katoh, Shigehito Sato, Tomoki Hashimoto, and Kazuo Umemura

Letter to the editor on "exposure to hazardous air pollutants and the risk of amyotrophic lateral sclerosis", Angela M. Malek, Aaron Barchowsky, Robert Bowser, Terry Heiman-Patterson, David Lacomis, Sandeep Rana, Ada Youk, and Evelyn O. Talbott

Exposure To Hazardous Air Pollutants And The Risk Of Amyotrophic Lateral Sclerosis, Angela M. Malek, Aaron Barchowsky, Robert Bowser, Terry Heiman-Patterson, David Lacomis, Sandeep Rana, Ada Youk, and Evelyn O. Talbott

In silico approach to evaluate the efficacy of dietary flavonoids and their role in Alzheimer's disease, Ruchi Jakhmola Mani, Khyati Mittal, Savita Mishra, Harsha Kharkwal, Saif Ahmad, and Deepshikha Pande Katare

The genetics of aneurysms: a complex pathophysiology requiring complex analysis, Michael M. McDowell and Andrew F. Ducruet

Time Is Brain: A Critical Analysis of the EXTEND-IA and ESCAPE Trials, Michael M. McDowell and Andrew F. Ducruet

Endoscopic endonasal atlantoaxial transarticular screw fixation technique: An anatomical feasibility and biomechanical study, George A.C. Mendes, Curtis A. Dickman, Nestor G. Rodriguez-Martinez, Samuel Kalb, Neil R. Crawford, Volker K.H. Sonntag, Mark C. Preul, and Andrew S. Little

Response, George A.C. Mendes, Curtis A. Dickman, Nestor G. Rodriguez-Martinez, Samuel Kalb, Neil R. Crawford, Volker K.H. Sonntag, Mark C. Preul, and Andrew S. Little

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DBS with versus without MER: Clinical equipoise or malpractice?, Zaman Mirzadeh and Francisco A. Ponce

Re: Letter to the editor regarding microelectrode recordings and deep brain stimulation surgery--Reasoned discussion?, Zaman Mirzadeh and Francisco A. Ponce

Reply: DBS with versus without MER: clinical equipoise or malpractice?, Zaman Mirzadeh and Francisco A. Ponce

Essential role for TMEM100 in vascular integrity but limited contributions to the pathogenesis of hereditary haemorrhagic telangiectasia, Eun Hye Moon, Yoo Sung Kim, Jiyoung Seo, Sabin Lee, Young Jae Lee, and Suk Paul Oh

Balloon remodeling of complex anterior communicating artery aneurysms: technical considerations and complications, Karam Moon, Felipe C. Albuquerque, Andrew F. Ducruet, R Webster Crowley, and Cameron G. McDougall

Methamphetamine use is an independent predictor of poor outcome after aneurysmal subarachnoid hemorrhage, Karam Moon, Felipe C. Albuquerque, Mario Mitkov, Andrew F. Ducruet, David A. Wilson, R Webster Crowley, Peter Nakaji, and Cameron G. McDougall

Hippocampal Plasticity During The Progression Of Alzheimer'S Disease, E. J. Mufson, L. Mahady, D. Waters, S. E. Counts, S. E. Perez, S. T. DeKosky, S. D. Ginsberg, M. D. Ikonomovic, S. W. Scheff, and L. I. Binder

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Resistance To Inhibitors Of Cholinesterase 3 (Ric-3) Expression Promotes Selective Protein Associations With The Human α7-Nicotinic Acetylcholine Receptor Interactome, Matthew J. Mulcahy, Sydney B. Blattman, Francisco J. Barrantes, Ronald J. Lukas, and Edward Hawrot

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Evidence for Alzheimer’s disease-linked synapse loss and compensation in mouse and human hippocampal CA1 pyramidal neurons, Krystina M. Neuman, Elizabeth Molina-Campos, Timothy F. Musial, Andrea L. Price, Kwang Jin Oh, Malerie L. Wolke, Eric W. Buss, Stephen W. Scheff, Elliott J. Mufson, and Daniel A. Nicholson

Succinate: A Promising Therapeutic Target for Reperfusion Injury, Alp Ozpinar, Gregory M. Weiner, and Andrew F. Ducruet

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Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration, Katrina L. Paumier, Kelvin C. Luk, Fredric P. Manfredsson, Nicholas M. Kanaan, Jack W. Lipton, Timothy J. Collier, Kathy Steece-Collier, Christopher J. Kemp, Stephanie Celano, Emily Schulz, Ivette M. Sandoval, Sheila Fleming, Elliott Dirr, Nicole K. Polinski, John Q. Trojanowski, Virginia M. Lee, and Caryl E. Sortwell

Hippocampal Endosomal Lysosomal And Autophagic Dysregulation In Mild Cognitive Impairment: Correlation With Aî² And Tau Pathology, Sylvia E. Perez, Bin He, Muhammad Nadeem, Joanne Wuu, Stephen D. Ginsberg, Milos D. Ikonomovic, and Elliott J. Mufson

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Resilience of precuneus neurotrophic signaling pathways despite amyloid pathology in prodromal Alzheimer's disease, Sylvia E. Perez, Bin He, Muhammad Nadeem, Joanne Wuu, Stephen W. Scheff, Eric E. Abrahamson, Milos D. Ikonomovic, and Elliott J. Mufson

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Cortical pyroglutamate amyloid-β levels and cognitive decline in Alzheimer's disease, Violetta N. Pivtoraiko, Eric E. Abrahamson, Sue E. Leurgans, Steven T. DeKosky, Elliott J. Mufson, and Milos D. Ikonomovic

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Recombinant adenoassociated virus 2/5-mediated gene transfer is reduced in the aged rat midbrain, Nicole K. Polinski, Sara E. Gombash, Fredric P. Manfredsson, Jack W. Lipton, Christopher J. Kemp, Allyson Cole-Strauss, Nicholas M. Kanaan, Kathy Steece-Collier, Nathan C. Kuhn, Susan L. Wohlgenant, and Caryl E. Sortwell

Intranasal Delivery Of Nemo-Binding Domain Peptide Prevents Memory Loss In A Mouse Model Of Alzheimer'S Disease, Suresh B. Rangasamy, Grant T. Corbett, Avik Roy, Khushbu K. Modi, David A. Bennett, Elliott J. Mufson, Sankar Ghosh, and Kalipada Pahan

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A Special Extract of Bacopa monnieri (CDRI-08)-Restored Memory in CoCl2-Hypoxia Mimetic Mice Is Associated with Upregulation of Fmr-1 Gene Expression in Hippocampus, Anupama Rani and S Prasad

To travel or not to travel: The modern day struggle of the academic researcher, Seward B. Rutkove, Jeremy M. Shefner, Robert Bowser, and Michael Benatar

The crucial role of vitamin C and its transporter (SVCT2) in bone marrow stromal cell autophagy and apoptosis, Rajnikumar Sangani, Sudharsan Periyasamy-Thandavan, Rajneesh Pathania, Saif Ahmad, Ammar Kutiyanawalla, Ravindra Kolhe, Maryka H. Bhattacharyya, Norman Chutkan, Monte Hunter, William D. Hill, Mark Hamrick, Carlos Isales, and Sadanand Fulzele

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Synaptic change in the posterior cingulate gyrus in the progression of Alzheimer's disease, Stephen W. Scheff, Douglas A. Price, Mubeen A. Ansari, Kelly N. Roberts, Frederick A. Schmitt, Milos D. Ikonomovic, and Elliott J. Mufson

Sustainability In A Hospital-Based Biobank And University-Based Dna Biorepository: Strategic Roadmaps, Catherine Y. Seiler, Jennifer Eschbacher, Robert Bowser, and Joshua Labaer

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Hyperactivation Of Bdnf-Trkb Signaling Cascades In Human Hypothalamic Hamartoma (Hh): A Potential Mechanism Contributing To Epileptogenesis, Suzan Semaan, Jie Wu, Yan Gan, Yu Jin, Guo Hui Li, John F. Kerrigan, Yong Chang, and Yao Huang

Amyotrophic Lateral Sclerosis: Is The Spinal Fluid Pathway Involved In Seeding And Spread?, Richard Smith, Kathleen Myers, John Ravits, and Robert Bowser

The effect of implant placement on sacroiliac joint range of motion: Posterior versus transarticular, Hector Soriano-Baron, Derek P. Lindsey, Nestor Rodriguez-Martinez, Phillip M. Reyes, Anna Newcomb, Scott A. Yerby, and Neil R. Crawford

High-Throughput Assay Development for Cystine-Glutamate Antiporter (xc-) Highlights Faster Cystine Uptake than Glutamate Release in Glioma Cells, Ajit G. Thomas, Rita Sattler, Karen Tendyke, Kara A. Loiacono, Hans Hansen, Vishal Sahni, Yutaka Hashizume, Camilo Rojas, and Barbara S. Slusher

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Amphiphilic cationic Zn-porphyrins with high photodynamic antimicrobial activity, Milini Thomas, James D. Craik, Artak Tovmasyan, Ines Batinic-Haberle, and Ludmil T. Benov

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α7 And β2 Nicotinic Acetylcholine Receptor Subunits Form Heteromeric Receptor Complexes That Are Expressed In The Human Cortex And Display Distinct Pharmacological Properties, Morten Skott Thomsen, Ruud Zwart, Daniel Ursu, Majbrit Myrup Jensen, Lars Hageman Pinborg, Gary Gilmour, Jie Wu, Emanuele Sher, and Jens Damsgaard Mikkelsen

A rare marginal tentorial artery to ophthalmic artery anastomosis, Daniel A. Tonetti, Ashutosh P. Jadhav, and Andrew F. Ducruet

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A comprehensive evaluation of catalase-like activity of different classes of redox-active therapeutics, Artak Tovmasyan, Clarissa G.C. Maia, Tin Weitner, Sebastián Carballal, Romulo S. Sampaio, Dominik Lieb, Robert Ghazaryan, Ivana Ivanovic-Burmazovic, Gerardo Ferrer-Sueta, Rafael Radi, Julio S. Reboucas, Ivan Spasojevic, Ludmil Benov, and Ines Batinic-Haberle

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Anticancer therapeutic potential of Mn porphyrin/ascorbate system, Artak Tovmasyan, Romulo S. Sampaio, Mary Keara Boss, Jacqueline C. Bueno-Janice, Bader H. Bader, Milini Thomas, Julio S. Reboucas, Michael Orr, Joshua D. Chandler, Young Mi Go, Dean P. Jones, Talaignair N. Venkatraman, Sinisa Haberle, Natalia Kyui, Christopher D. Lascola, Mark W. Dewhirst, Ivan Spasojevic, Ludmil Benov, and Ines Batinic-Haberle

Valproic acid treatment after experimental subarachnoid hemorrhage, Michael K. Tso, Elliot Lass, Jinglu Ai, and R. Loch Macdonald

Mouse models of hereditary hemorrhagic telangiectasia: Recent advances and future challenges, Simon Tual-Chalot, S. Paul Oh, and Helen M. Arthur

Chemical exchange in knee cartilage assessed by R1ρ (1/T1ρ) dispersion at 3T., Ping Wang, Jake Block, and John C Gore

Effects of flip angle uncertainty and noise on the accuracy of DCE-MRI metrics: comparison between standard concentration-based and signal difference methods., Ping Wang, Yiqun Xue, Xia Zhao, Jiangsheng Yu, Mark Rosen, and Hee Kwon Song

Evidence for a neuroprotective microRNA pathway in amnestic mild cognitive impairment, Rebecca B. Weinberg, Elliott J. Mufson, and Scott E. Counts

ESCAPE Trial Supports Rapid Endovascular Thrombectomy in the Management of Large-Vessel Acute Ischemic Stroke, Gregory M. Weiner and Andrew F. Ducruet

Mammalian target of rapamycin (mTOR) activity promotes neuronal survival in stroke with or without ischemic postconditioning, Gregory M. Weiner and Andrew F. Ducruet

The use of nanotechnology to improve the neuroprotective effects of adenosine in stroke and spinal cord injury, Gregory M. Weiner, Amir H. Faraji, and Andrew F. Ducruet

Radioprotection of the brain white matter by Mn(III) n-Butoxyethylpyridylporphyrin-based superoxide dismutase mimic MnTnBuOE-2-PyP5+, Douglas H. Weitzel, Artak Tovmasyan, Kathleen A. Ashcraft, Zrinka Rajic, Tin Weitner, Chunlei Liu, Wei Li, Anne F. Buckley, Mark R. Prasad, Kenneth H. Young, Ramona M. Rodriguiz, William C. Wetsel, Katherine B. Peters, Ivan Spasojevic, James E. Herndon, Ines Batinic-Haberle, and Mark W. Dewhirst

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Mechanisms Of Intrinsic Epileptogenesis In Human Gelastic Seizures With Hypothalamic Hamartoma, Jie Wu, Ming Gao, Jian Xin Shen, Shen Feng Qiu, and John F. Kerrigan

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Toxic Oligomeric Alpha-Synuclein Variants Present In Human Parkinson’S Disease Brains Are Differentially Generated In Mammalian Cell Models, Wei Xin, Sharareh Emadi, Stephanie Williams, Qiang Liu, Philip Schulz, Ping He, Now Bahar Alam, Jie Wu, and Michael R. Sierks

Therapeutically targeting tumor necrosis factor-α/ sphingosine-1-phosphate signaling corrects myogenic reactivity in subarachnoid hemorrhage, Kenji Yagi, Darcy Lidington, Hoyee Wan, Jessica C. Fares, Anja Meissner, Manabu Sumiyoshi, Jinglu Ai, Warren D. Foltz, Sergei A. Nedospasov, Stefan Offermanns, Shinji Nagahiro, R. Loch Macdonald, and Steffen Sebastian Bolz

The Coupling Interface And Pore Domain Codetermine The Single-Channel Activity Of The α7 Nicotinic Receptor, Hongxia Yan, Na Pan, Fenqin Xue, Yan Zheng, Chaokun Li, Yongchang Chang, Zhiqing Xu, Hui Yang, and Jianliang Zhang

Evaluation of genetic risk scores for prediction of dichotomous outcomes, Wonsuk Yoo, Selina A. Smith, and Steven S. Coughlin

The C9orf72 repeat expansion disrupts nucleocytoplasmic transport, Ke Zhang, Christopher J. Donnelly, Aaron R. Haeusler, Jonathan C. Grima, James B. Machamer, Peter Steinwald, Elizabeth L. Daley, Sean J. Miller, Kathleen M. Cunningham, Svetlana Vidensky, Saksham Gupta, Michael A. Thomas, Ingie Hong, Shu-Ling Chiu, Richard L. Huganir, Lyle W. Ostrow, Michael J. Matunis, Jiou Wang, Rita Sattler, Thomas E. Lloyd, and Jeffrey D. Rothstein

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Functional Impact Of 14 Single Nucleotide Polymorphisms Causing Missense Mutations Of Human α7 Nicotinic Receptor, Qinhui Zhang, Yingjie Du, Jianliang Zhang, Xiaojun Xu, Fenqin Xue, Cong Guo, Yao Huang, Ronald J. Lukas, and Yongchang Chang

Combination Of The Immune Modulator Fingolimod With Alteplase In Acute Ischemic Stroke: A Pilot Trial, Zilong Zhu, Ying Fu, Decai Tian, Na Sun, Wei Han, Guoqiang Chang, Yinhua Dong, Xiaolin Xu, Qiang Liu, Deren Huang, and Fu Dong Shi

Submissions from 2014

Mutant disrupted-in-schizophrenia 1 in astrocytes: focus on glutamate metabolism, Sofya Abazyan, Eun Ju Yang, Bagrat Abazyan, Meng Xia, Chunxia Yang, Camilo Rojas, Barbara Slusher, Rita Sattler, and Mikhail Pletnikov

Inhibition of adenosine kinase attenuates inflammation and neurotoxicity in traumatic optic neuropathy, Saif Ahmad, Nehal M. Elsherbiny, Kanchan Bhatia, Ahmed M. Elsherbini, Sadanand Fulzele, and Gregory I. Liou

Sesamin attenuates neurotoxicity in mouse model of ischemic brain stroke, Saif Ahmad, Nehal M. Elsherbiny, Rizwanul Haque, M. Badruzzaman Khan, Tauheed Ishrat, Zahoor A. Shah, Mohammad M. Khan, Mehboob Ali, Arshad Jamal, Deepshikha Pande Katare, Gregory I. Liou, and Kanchan Bhatia

Habb-e-Asgand, polyherbal Unani formulation, protects liver and antioxidative enzymes against paracetamol induced hepatotoxicity, Mehboob Ali, Sagheer Ahmed Khan, Peter S. Chang, Rizwanul Haque, Kanchan Bhatia, and Saif Ahmad

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Maternal choline supplementation improves spatial mapping and increases basal forebrain cholinergic neuron number and size in aged Ts65Dn mice, Jessica A. Ash, Ramon Velazquez, Christy M. Kelley, Brian E. Powers, Stephen D. Ginsberg, Elliott J. Mufson, and Barbara J. Strupp

Radiographic assessment of thoracolumbar fractures based on axial zones, Ali A. Baaj, Brian R. Gantwerker, Nicholas Theodore, Juan S. Uribe, Fernando L. Vale, Neil R. Crawford, and Volker K.H. Sonntag

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SOD therapeutics: latest insights into their structure-activity relationships and impact on the cellular redox-based signaling pathways, Ines Batinic-Haberle, Artak Tovmasyan, Emily R.H. Roberts, Zeljko Vujaskovic, Kam W. Leong, and Ivan Spasojevic

ALSUntangled no. 26: Lunasin, Richard Bedlack, Colin Quinn, Chafic Karam, Alex Sherman, Lyle Ostrow, Orla Hardiman, Terry Heiman-Patterson, Laurie Gutmann, Mark Bromberg, Gregory Carter, Edor Kabashi, Tulio Bertorini, Tahseen Mozaffar, Peter Andersen, Jeff Dietz, Josep Gamez, Mazen Dimachkie, Yunxia Wang, Paul Wicks, James Heywood, Steven Novella, L. P. Rowland, Erik Pioro, Lisa Kinsley, Kathy Mitchell, Jonathan Glass, Sith Sathornsumetee, Hubert Kwiecinski, Jon Baker, Nazem Atassi, and Dallas Forshew

Platelet-mediated changes to neuronal glutamate receptor expression at sites of microthrombosis following experimental subarachnoid hemorrhage: Laboratory investigation, Joshua D. Bell, Theresa Currier Thomas, Elliot Lass, Jinglu Ai, Hoyee Wan, Jonathan Lifshitz, Andrew J. Baker, and R. Loch MacDonald

Endothelin-1-mediated vasoconstriction alters cerebral gene expression in iron homeostasis and eicosanoid metabolism, Justin S. Bickford, Narjis F. Ali, Jerelyn A. Nick, Musab Al-Yahia, Dawn E. Beachy, Sylvain Doré, Harry S. Nick, and Michael F. Waters

ALSUntangled no. 23: the Rife machine and retroviruses., Robert Bowser and ALSUntangled Group

ALSUntangled No. 24: Vitamin D., Robert Bowser and ALSUntangled Group

ALSUntangled no. 25: ursodiol., Robert Bowser and ALSUntangled Group

Vagus nerve stimulation in ischemic stroke: old wine in a new bottle, Peter Y. Cai, Aakash Bodhit, Roselle Derequito, Saeed Ansari, Fawzi Abukhalil, Spandana Thenkabail, Sarah Ganji, Pradeepan Saravanapavan, Chandana C. Shekar, Sharatchandra Bidari, Michael F. Waters, and Vishnumurthy Shushrutha Hedna

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Mn porphyrin-based SOD mimic, MnTnHex-2-PyP5+, and non-SOD mimic, MnTBAP3-, suppressed rat spinal cord ischemia/reperfusion injury via NF-κB pathways, T. Celic, J. Španjol, M. Bobinac, A. Tovmasyan, I. Vukelic, J. S. Reboucas, I. Batinic-Haberle, and D. Bobinac

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Collaborative approach in the development of high-performance brain-computer interfaces for a neuroprosthetic arm: translation from animal models to human control, Jennifer L. Collinger, Michael A. Kryger, Richard Barbara, Timothy Betler, Kristen Bowsher, Elke H. Brown, Samuel T. Clanton, Alan D. Degenhart, Stephen T. Foldes, Robert A. Gaunt, Ferenc E. Gyulai, Elizabeth A. Harchick, Deborah Harrington, John B. Helder, Timothy Hemmes, Matthew S. Johannes, Kapil D. Katyal, Geoffrey S. Ling, Angus J. McMorland, Karina Palko, Matthew P. Para, Janet Scheuermann, Andrew B. Schwartz, Elizabeth R. Skidmore, Florian Solzbacher, Anita V. Srikameswaran, Dennis P. Swanson, Scott Swetz, Elizabeth C. Tyler-Kabara, Meel Velliste, Wei Wang, and Douglas J. Weber

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Synaptic gene dysregulation within hippocampal CA1 pyramidal neurons in mild cognitive impairment, Scott E. Counts, Melissa J. Alldred, Shaoli Che, Stephen D. Ginsberg, and Elliott J. Mufson

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Intravenous immunoglobulin reduces tau pathology and preserves neuroplastic gene expression in the 3xTg mouse model of Alzheimer's disease, Scott E. Counts, Sylvia E. Perez, Bin He, and Elliott J. Mufson

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Intravenous immunoglobulin (IVIG) treatment exerts antioxidant and neuropreservatory effects in preclinical models of Alzheimer's disease, Scott E. Counts, Balmiki Ray, Elliott J. Mufson, Sylvia E. Perez, Bin He, and Debomoy K. Lahiri

Futsch/Map1B Mrna Is A Translational Target Of Tdp-43 And Is Neuroprotective In A Drosophila Model Of Amyotrophic Lateral Sclerosis, Alyssa N. Coyne, Bhavani Bagevalu Siddegowda, Patricia S. Estes, Jeffrey Johannesmeyer, Tina Kovalik, Scott G. Daniel, Antony Pearson, Robert Bowser, and Daniela C. Zarnescu

Endovascular advances for brain arteriovenous malformations, R Webster Crowley, Andrew F. Ducruet, Cameron G. McDougall, and Felipe C. Albuquerque

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Roles For N-Terminal Extracellular Domains Of Nicotinic Acetylcholine Receptor (Nachr) β3 Subunits In Enhanced Functional Expression Of Mouse α6β2β3- And α6β4β3-Nachrs, Bhagirathi Dash, Ming D. Li, and Ronald J. Lukas

A Signal Peptide Missense Mutation Associated With Nicotine Dependence Alters α2*-Nicotinic Acetylcholine Receptor Function, Bhagirathi Dash, Ronald J. Lukas, and Ming D. Li

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Aberrant RNA homeostasis in amyotrophic lateral sclerosis: potential for new therapeutic targets?, Christopher J. Donnelly, Jonathan C. Grima, and Rita Sattler

Long-term patency of venous sinus stents for idiopathic intracranial hypertension, Andrew F. Ducruet, R Webster Crowley, Cameron G. McDougall, and Felipe C. Albuquerque

The Unique α4(1)/(2)α4 Agonist Binding Site In (α4)3(β2)2 Subtype Nicotinic Acetylcholine Receptors Permits Differential Agonist Desensitization Pharmacology Versus The (α4)2(β2)3 Subtypes, J. Brek Eaton, Linda M. Lucero, Harrison Stratton, Yongchang Chang, John F. Cooper, Jon M. Lindstrom, Ronald J. Lukas, and Paul Whiteaker

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Mn porphyrin in combination with ascorbate acts as a pro-oxidant and mediates caspase-independent cancer cell death, Myron K. Evans, Artak Tovmasyan, Ines Batinic-Haberle, and Gayathri R. Devi

Volume curtaining: A focus+context effect for multimodal volume visualization, Adam J. Fairfield, Jonathan Plasencia, Yun Jang, Nicholas Theodore, Neil R. Crawford, David H. Frakes, and Ross Maciejewski

Impact Of An Immune Modulator Fingolimod On Acute Ischemic Stroke, Ying Fu, Ningnannan Zhang, Li Ren, Yaping Yan, Na Sun, Yu Jing Li, Wei Han, Rong Xue, Qiang Liu, Junwei Hao, Chunshui Yu, and Fu Dong Shi

KCNC3(R420H), a K(+) channel mutation causative in spinocerebellar ataxia 13 displays aberrant intracellular trafficking, Carolina Gallego-Iradi, Justin S. Bickford, Swati Khare, Alexis Hall, Jerelyn A. Nick, Donya Salmasinia, Kolja Wawrowsky, Serguei Bannykh, Duong P. Huynh, Diego E. Rincon-Limas, Stefan M. Pulst, Harry S. Nick, Pedro Fernandez-Funez, and Michael F. Waters

Ischemic Neurons Recruit Natural Killer Cells That Accelerate Brain Infarction, Yan Gan, Qiang Liu, Wei Wu, Jun Xiang Yin, Xue Feng Bai, Rulong Shen, Yongjun Wang, Jieli Chen, Antonio La Cava, Jennifer Poursine-Laurent, Wayne Yokoyama, and Fu Dong Shi

Common and distinctive pathogenetic features of arteriovenous malformations in hereditary hemorrhagic telangiectasia 1 and hereditary hemorrhagic telangiectasia 2 animal models - Brief report, Eva M. Garrido-Martin, Ha Long Nguyen, Tyler A. Cunningham, Se Woon Choe, Zhihua Jiang, Helen M. Arthur, Young Jae Lee, and S. Paul Oh

Robust rat pulmonary radioprotection by a lipophilic Mn N-alkylpyridylporphyrin, MnTnHex-2-PyP(5+), Benjamin Gauter-Fleckenstein, Julio S. Reboucas, Katharina Fleckenstein, Artak Tovmasyan, Kouros Owzar, Chen Jiang, Ines Batinic-Haberle, and Zeljko Vujaskovic

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Neuroprotective potential of pleiotrophin overexpression in the striatonigral pathway compared with overexpression in both the striatonigral and nigrostriatal pathways, S. E. Gombash, F. P. Manfredsson, R. J. Mandel, T. J. Collier, D. L. Fischer, C. J. Kemp, N. M. Kuhn, S. L. Wohlgenant, S. M. Fleming, and C. E. Sortwell

Talonavicular joint fixation: a biomechanical comparison of locking compression plates and lag screws., Jaymes D Granata, Gregory C Berlet, Rahul Ghotge, Yuan Li, Brian Kelly, and Denis DiAngelo

C9orf72 nucleotide repeat structures initiate molecular cascades of disease, Aaron R. Haeusler, Christopher J. Donnelly, Goran Periz, Eric A. Simko, Patrick G. Shaw, Min-Sik Kim, Nicholas J. Maragakis, Juan C. Troncoso, Akhilesh Pandey, Rita Sattler, Jeffrey D. Rothstein, and Jiou Wang

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U1 small nuclear ribonucleoproteins (snRNPs) aggregate in Alzheimer's disease due to autosomal dominant genetic mutations and trisomy 21, Chadwick M. Hales, Nicholas T. Seyfried, Eric B. Dammer, Duc Duong, Hong Yi, Marla Gearing, Juan C. Troncoso, Elliott J. Mufson, Madhav Thambisetty, Allan I. Levey, and James J. Lah

VEGF neutralization can prevent and normalize arteriovenous malformations in an animal model for hereditary hemorrhagic telangiectasia 2, Chul Han, Se Woon Choe, Yong Hwan Kim, Abhinav P. Acharya, Benjamin G. Keselowsky, Brian S. Sorg, Young Jae Lee, and S. Paul Oh

Molecular alterations in the hippocampus after experimental subarachnoid hemorrhage, Sang Myung Han, Hoyee Wan, Gen Kudo, Warren D. Foltz, Douglass C. Vines, David E. Green, Tommaso Zoerle, Asma Tariq, Shakira Brathwaite, Josephine D'Abbondanza, Jinglu Ai, and R. Loch Macdonald

Intracranial hypotension masquerading as nonconvulsive status epilepticus: report of 3 cases, Vishnumurthy Shushrutha Hedna, Abhay Kumar, Bayard Miller, Sharathchandra Bidari, Arash Salardini, Michael F. Waters, Maria Hella, Edward Valenstein, and Stephan Eisenschenk