The Barrow Neurological Institute is proud of its reputation as a medical research facility and is home to some of the most sophisticated research programs outside of an academic setting in the Southwestern United States. Researchers in the Barrow Neurosurgery Research Center are devoted to learning more about the causes of and treatments for a wide range of disorders, such as stroke, aneurysms, spinal cord injury, and hydrocephalus. Our research has led to treatments that are being used around the world. Within the Department are neurosurgeons who subspecialize in cerebrovascular and skull base, functional and stereotactic, pediatric, spine, tumor, and endovascular neurosurgery.

Physicians, scientists, and expert clinical staff come together with a commitment to developing new techniques for the prevention, diagnosis, treatment, and rehabilitation of neurological illnesses and injuries. The leadership of internationally respected physicians keeps Barrow at the forefront of neuroscience. The compassionate expertise of its extensive staff of nurses, technologists, therapists and support personnel is evident in every aspect of care provided.

Our mission is to advance the knowledge and practice of medicine in neuroscience through basic and clinical research, education of medical professionals, and innovation in clinical techniques and technology.

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Submissions from 2015

Coil herniation following intra-arterial verapamil infusion for the treatment of cerebral vasospasm: Case report and literature review, Stephanie H. Chen, Ramesh Grandhi, Christopher P. Deibert, Tudor G. Jovin, Paul A. Gardner, and Andrew F. Ducruet

Stability of transforaminal lumbar interbody fusion in the setting of retained facets and posterior fixation using transfacet or standard pedicle screws, Kingsley R. Chin, Marco T. Reis, Phillip M. Reyes, Anna G.U. Newcomb, Anda Neagoe, Josue P. Gabriel, Roger D. Sung, and Neil R. Crawford

The Dynamic Gait Index in Evaluating Patients with Normal Pressure Hydrocephalus for Cerebrospinal Fluid Diversion, Srinivas Chivukula, Zachary J. Tempel, Nathan T. Zwagerman, W Christopher Newman, Samuel S. Shin, Ching-Jen Chen, Paul A. Gardner, Eric M. McDade, and Andrew F. Ducruet

Mitochondrial ATP transporter Ant2 depletion impairs erythropoiesis and B lymphopoiesis, J. Cho, J. Seo, C. H. Lim, L. Yang, T. Shiratsuchi, M. H. Lee, R. R. Chowdhury, H. Kasahara, J. S. Kim, S. P. Oh, Y. J. Lee, and N. Terada

Label-Free Lc-Ms/Ms Proteomic Analysis Of Cerebrospinal Fluid Identifies Protein/Pathway Alterations And Candidate Biomarkers For Amyotrophic Lateral Sclerosis, Mahlon A. Collins, Jiyan An, Brian L. Hood, Thomas P. Conrads, and Robert P. Bowser

Total Protein Is An Effective Loading Control For Cerebrospinal Fluid Western Blots, Mahlon A. Collins, Jiyan An, Danielle Peller, and Robert Bowser

Advancing breast cancer survivorship among African-American women, Steven S. Coughlin, Wonsuk Yoo, Mary S. Whitehead, and Selina A. Smith

Neurological morbidity and mortality associated with the endovascular treatment of cerebral arteriovenous malformations before and during the Onyx era, R Webster Crowley, Andrew F. Ducruet, M Yashar Kalani, Louis J. Kim, Felipe C. Albuquerque, and Cameron G. McDougall

Mouse genetic background is associated with variation in secondary complications after subarachnoid hemorrhage, Josephine A. D’Abbondanza, Elliot Lass, Jinglu Ai, and R. Loch Macdonald

20-HETE is associated with unfavorable outcomes in subarachnoid hemorrhage patients, Mark K. Donnelly, Elizabeth A. Crago, Yvette P. Conley, Jeffery R. Balzer, Dianxu Ren, Andrew F. Ducruet, Patrick M. Kochanek, Paula R. Sherwood, and Samuel M. Poloyac

Erratum to: The surgical management of chronic subdural hematoma, Andrew F. Ducruet, Bartosz T. Grobelny, Brad E. Zacharia, Zachary L. Hickman, Peter L. DeRosa, Kristen N. Andersen, Eric Sussman, Austin Carpenter, and E Sander Connolly

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Transcriptome And Expression Profiling Analysis Link Patterns Of Gene Expression To Antennal Responses In Spodoptera Litura, Bo Feng, Xinda Lin, Kaidi Zheng, Kai Qian, Yongchang Chang, and Yongjun Du

The role of endoscopic assistance in ambient cistern surgery: Analysis of four surgical approaches, Eberval Gadelha Figueiredo, André Beer-Furlan, Peter Nakaji, Neil Crawford, Leonardo C. Welling, Eduardo C. Ribas, Manoel J. Teixeira, Albert L. Rhoton, Robert F. Spetzler, and Mark C. Preul

High-Frequency Stimulation of the Rat Entopeduncular Nucleus Does Not Provide Functional or Morphological Neuroprotection from 6-Hydroxydopamine, D Luke Fischer, Timothy J. Collier, Allyson Cole-Strauss, Susan L. Wohlgenant, Jack W. Lipton, Kathy Steece-Collier, Fredric P. Manfredsson, Christopher J. Kemp, and Caryl E. Sortwell

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MEG-based neurofeedback for hand rehabilitation, Stephen T. Foldes, Douglas J. Weber, and Jennifer L. Collinger

MicroRNA-146b-3p regulates retinal inflammation by suppressing adenosine deaminase-2 in diabetes, Sadanand Fulzele, Ahmed El-Sherbini, Saif Ahmad, Rajnikumar Sangani, Suraporn Matragoon, Azza El-Remessy, Reshmitha Radhakrishnan, and Gregory I. Liou

Genetic inhibition of JNK3 ameliorates spinal muscular atrophy, Naresh K. Genabai, Saif Ahmad, Zhanying Zhang, Xiaoting Jiang, Cynthia A. Gabaldon, and Laxman Gangwani

A method for combining RNAscope in situ hybridization with immunohistochemistry in thick free-floating brain sections and primary neuronal cultures, Tessa M. Grabinski, Andrew Kneynsberg, Fredric P. Manfredsson, and Nicholas M. Kanaan

Administration of 4-Factor Prothrombin Complex Concentrate as an Antidote for Intracranial Bleeding in Patients Taking Direct Factor Xa Inhibitors, Ramesh Grandhi, W Christopher Newman, Xiaoran Zhang, Gillian Harrison, Colleen Moran, David O. Okonkwo, and Andrew F. Ducruet

Incidence of delayed angiographic femoral artery complications using the EXOSEAL vascular closure device, Ramesh Grandhi, Xiaoran Zhang, David Panczykowski, Phillip Choi, Christopher T. Hunnicutt, Ashutosh P. Jadhav, Andrew F. Ducruet, Tudor Jovin, and Brian Jankowitz

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Brain computer interface learning for systems based on electrocorticography and intracortical microelectrode arrays, Shivayogi V. Hiremath, Weidong Chen, Wei Wang, Stephen Foldes, Ying Yang, Elizabeth C. Tyler-Kabara, Jennifer L. Collinger, and Michael L. Boninger

Neuropilin 1 balances β8 integrin-activated TGFβ signaling to control sprouting angiogenesis in the brain, Shinya Hirota, Thomas P. Clements, Leung K. Tang, John E. Morales, Hye Shin Lee, S. Paul Oh, Gonzalo M. Rivera, Daniel S. Wagner, and Joseph H. McCarty

α-Conotoxins Identify The α3β4ˆ— Subtype As The Predominant Nicotinic Acetylcholine Receptor Expressed In Human Adrenal Chromaffin Cells, Arik J. Hone, J. Michael McIntosh, Layla Azam, Jon Lindstrom, Linda Lucero, Paul Whiteaker, Juan Passas, Jesús Blázquez, and Almudena Albillos

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Proteolytic Regulation Of Epithelial Sodium Channels By Urokinase Plasminogen Activator: Cutting Edge And Cleavage Sites, Hong Long Ji, Runzhen Zhao, Andrey A. Komissarov, Yongchang Chang, Yongfeng Liu, and Michael A. Matthay

The longitudinal transcriptomic response of the substantia nigra to intrastriatal 6-hydroxydopamine reveals significant upregulation of regeneration-associated genes, Nicholas M. Kanaan, Timothy J. Collier, Allyson Cole-Strauss, Tessa Grabinski, Zachary R. Mattingly, Mary E. Winn, Kathy Steece-Collier, Caryl E. Sortwell, Fredric P. Manfredsson, and Jack W. Lipton

Xenopus laevis FGF receptor substrate 3 (XFrs3) is important for eye development and mediates Pax6 expression in lens placode through its Shp2-binding sites., Yeon-Jin Kim, Minjin Bahn, Yong Hwan Kim, Jee-Yoon Shin, Seon-Woo Cheong, Bong-Gun Ju, Won-Sun Kim, and Chang-Yeol Yeo

Epileptic focus localization based on resting state interictal MEG recordings is feasible irrespective of the presence or absence of spikes, B Krishnan, I Vlachos, Z I. Wang, J Mosher, I Najm, R Burgess, L Iasemidis, and A V. Alexopoulos

Haptoglobin phenotype predicts the development of focal and global cerebral vasospasm and may influence outcomes after aneurysmal subarachnoid hemorrhage, Jenna L. Leclerc, Spiros Blackburn, Dan Neal, Nicholas V. Mendez, Jeffrey A. Wharton, Michael F. Waters, and Sylvain Doré

Adenine nucleotide translocase 4 is expressed within embryonic ovaries and dispensable during oogenesis, Chae Ho Lim, Jeffrey V. Brower, James L. Resnick, S. Paul Oh, and Naohiro Terada

A Novel Nicotinic Mechanism Underlies β-Amyloid-Induced Neurotoxicity, Qiang Liu, Xitao Xie, Sharareh Emadi, Michael R. Sierks, and Jie Wu

Roles Of Nicotinic Acetylcholine Receptor β Subunit Cytoplasmic Loops In Acute Desensitization And Single-Channel Features, Q. Liu, Y. P. Kuo, J. Shen, R. J. Lukas, and J. Wu

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Activation Of α7 Nicotinic Acetylcholine Receptors Prevents Monosodium Iodoacetate-Induced Osteoarthritis In Rats, Yuan Liu, Dongying Wu, Fanglong Song, Chenlei Zhu, Yujian Hui, Qingcheng Zhu, Jie Wu, Weimin Fan, and Jun Hu

Activation Of α7 Nicotinic Acetylcholine Receptors Protects Astrocytes Against Oxidative Stress-Induced Apoptosis: Implications For Parkinson'S Disease, Yuan Liu, Xiaoning Zeng, Yujian Hui, Chenlei Zhu, Jie Wu, Devin H. Taylor, Juan Ji, Weimin Fan, Zuhu Huang, and Jun Hu

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Rbm45 Homo-Oligomerization Mediates Association With Als-Linked Proteins And Stress Granules, Yang Li, Mahlon Collins, Rachel Geiser, Nadine Bakkar, David Riascos, and Robert Bowser

A comprehensive library of familial human amyotrophic lateral sclerosis induced pluripotent stem cells, Ying Li, Umamahesw Balasubramanian, Devon Cohen, Ping-Wu Zhang, Elizabeth Mosmiller, Rita Sattler, Nicholas J. Maragakis, and Jeffrey D. Rothstein

Association of Circulating Follicular Helper T Cells With Disease Course of NMO Spectrum Disorders, Yu Jing Li, Fang Zhang, Yuan Qi, Guo Qiang Chang, Ying Fu, Lei Su, Yi Shen, Na Sun, Aimee Borazanci, Chunsheng Yang, Fu-Dong Shi, and Yaping Yan

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Successful serial imaging of the mouse cerebral arteries using conventional 3-T magnetic resonance imaging, Hiroshi Makino, Kazuya Hokamura, Takahiro Natsume, Tetsuro Kimura, Yoshinobu Kamio, Yasuhiro Magata, Hiroki Namba, Takasumi Katoh, Shigehito Sato, Tomoki Hashimoto, and Kazuo Umemura

Letter to the editor on "exposure to hazardous air pollutants and the risk of amyotrophic lateral sclerosis", Angela M. Malek, Aaron Barchowsky, Robert Bowser, Terry Heiman-Patterson, David Lacomis, Sandeep Rana, Ada Youk, and Evelyn O. Talbott

Exposure To Hazardous Air Pollutants And The Risk Of Amyotrophic Lateral Sclerosis, Angela M. Malek, Aaron Barchowsky, Robert Bowser, Terry Heiman-Patterson, David Lacomis, Sandeep Rana, Ada Youk, and Evelyn O. Talbott

In silico approach to evaluate the efficacy of dietary flavonoids and their role in Alzheimer's disease, Ruchi Jakhmola Mani, Khyati Mittal, Savita Mishra, Harsha Kharkwal, Saif Ahmad, and Deepshikha Pande Katare

The genetics of aneurysms: a complex pathophysiology requiring complex analysis, Michael M. McDowell and Andrew F. Ducruet

Time Is Brain: A Critical Analysis of the EXTEND-IA and ESCAPE Trials, Michael M. McDowell and Andrew F. Ducruet

Endoscopic endonasal atlantoaxial transarticular screw fixation technique: An anatomical feasibility and biomechanical study, George A.C. Mendes, Curtis A. Dickman, Nestor G. Rodriguez-Martinez, Samuel Kalb, Neil R. Crawford, Volker K.H. Sonntag, Mark C. Preul, and Andrew S. Little

Response, George A.C. Mendes, Curtis A. Dickman, Nestor G. Rodriguez-Martinez, Samuel Kalb, Neil R. Crawford, Volker K.H. Sonntag, Mark C. Preul, and Andrew S. Little

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DBS with versus without MER: Clinical equipoise or malpractice?, Zaman Mirzadeh and Francisco A. Ponce

Re: Letter to the editor regarding microelectrode recordings and deep brain stimulation surgery--Reasoned discussion?, Zaman Mirzadeh and Francisco A. Ponce

Reply: DBS with versus without MER: clinical equipoise or malpractice?, Zaman Mirzadeh and Francisco A. Ponce

Essential role for TMEM100 in vascular integrity but limited contributions to the pathogenesis of hereditary haemorrhagic telangiectasia, Eun Hye Moon, Yoo Sung Kim, Jiyoung Seo, Sabin Lee, Young Jae Lee, and Suk Paul Oh

Balloon remodeling of complex anterior communicating artery aneurysms: technical considerations and complications, Karam Moon, Felipe C. Albuquerque, Andrew F. Ducruet, R Webster Crowley, and Cameron G. McDougall

Methamphetamine use is an independent predictor of poor outcome after aneurysmal subarachnoid hemorrhage, Karam Moon, Felipe C. Albuquerque, Mario Mitkov, Andrew F. Ducruet, David A. Wilson, R Webster Crowley, Peter Nakaji, and Cameron G. McDougall

Hippocampal Plasticity During The Progression Of Alzheimer'S Disease, E. J. Mufson, L. Mahady, D. Waters, S. E. Counts, S. E. Perez, S. T. DeKosky, S. D. Ginsberg, M. D. Ikonomovic, S. W. Scheff, and L. I. Binder

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Resistance To Inhibitors Of Cholinesterase 3 (Ric-3) Expression Promotes Selective Protein Associations With The Human α7-Nicotinic Acetylcholine Receptor Interactome, Matthew J. Mulcahy, Sydney B. Blattman, Francisco J. Barrantes, Ronald J. Lukas, and Edward Hawrot

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Evidence for Alzheimer’s disease-linked synapse loss and compensation in mouse and human hippocampal CA1 pyramidal neurons, Krystina M. Neuman, Elizabeth Molina-Campos, Timothy F. Musial, Andrea L. Price, Kwang Jin Oh, Malerie L. Wolke, Eric W. Buss, Stephen W. Scheff, Elliott J. Mufson, and Daniel A. Nicholson

Succinate: A Promising Therapeutic Target for Reperfusion Injury, Alp Ozpinar, Gregory M. Weiner, and Andrew F. Ducruet

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Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration, Katrina L. Paumier, Kelvin C. Luk, Fredric P. Manfredsson, Nicholas M. Kanaan, Jack W. Lipton, Timothy J. Collier, Kathy Steece-Collier, Christopher J. Kemp, Stephanie Celano, Emily Schulz, Ivette M. Sandoval, Sheila Fleming, Elliott Dirr, Nicole K. Polinski, John Q. Trojanowski, Virginia M. Lee, and Caryl E. Sortwell

Hippocampal Endosomal Lysosomal And Autophagic Dysregulation In Mild Cognitive Impairment: Correlation With Aî² And Tau Pathology, Sylvia E. Perez, Bin He, Muhammad Nadeem, Joanne Wuu, Stephen D. Ginsberg, Milos D. Ikonomovic, and Elliott J. Mufson

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Resilience of precuneus neurotrophic signaling pathways despite amyloid pathology in prodromal Alzheimer's disease, Sylvia E. Perez, Bin He, Muhammad Nadeem, Joanne Wuu, Stephen W. Scheff, Eric E. Abrahamson, Milos D. Ikonomovic, and Elliott J. Mufson

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Cortical pyroglutamate amyloid-β levels and cognitive decline in Alzheimer's disease, Violetta N. Pivtoraiko, Eric E. Abrahamson, Sue E. Leurgans, Steven T. DeKosky, Elliott J. Mufson, and Milos D. Ikonomovic

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Recombinant adenoassociated virus 2/5-mediated gene transfer is reduced in the aged rat midbrain, Nicole K. Polinski, Sara E. Gombash, Fredric P. Manfredsson, Jack W. Lipton, Christopher J. Kemp, Allyson Cole-Strauss, Nicholas M. Kanaan, Kathy Steece-Collier, Nathan C. Kuhn, Susan L. Wohlgenant, and Caryl E. Sortwell

Intranasal Delivery Of Nemo-Binding Domain Peptide Prevents Memory Loss In A Mouse Model Of Alzheimer'S Disease, Suresh B. Rangasamy, Grant T. Corbett, Avik Roy, Khushbu K. Modi, David A. Bennett, Elliott J. Mufson, Sankar Ghosh, and Kalipada Pahan

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A Special Extract of Bacopa monnieri (CDRI-08)-Restored Memory in CoCl2-Hypoxia Mimetic Mice Is Associated with Upregulation of Fmr-1 Gene Expression in Hippocampus, Anupama Rani and S Prasad

To travel or not to travel: The modern day struggle of the academic researcher, Seward B. Rutkove, Jeremy M. Shefner, Robert Bowser, and Michael Benatar

The crucial role of vitamin C and its transporter (SVCT2) in bone marrow stromal cell autophagy and apoptosis, Rajnikumar Sangani, Sudharsan Periyasamy-Thandavan, Rajneesh Pathania, Saif Ahmad, Ammar Kutiyanawalla, Ravindra Kolhe, Maryka H. Bhattacharyya, Norman Chutkan, Monte Hunter, William D. Hill, Mark Hamrick, Carlos Isales, and Sadanand Fulzele

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Synaptic change in the posterior cingulate gyrus in the progression of Alzheimer's disease, Stephen W. Scheff, Douglas A. Price, Mubeen A. Ansari, Kelly N. Roberts, Frederick A. Schmitt, Milos D. Ikonomovic, and Elliott J. Mufson

Sustainability In A Hospital-Based Biobank And University-Based Dna Biorepository: Strategic Roadmaps, Catherine Y. Seiler, Jennifer Eschbacher, Robert Bowser, and Joshua Labaer

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Hyperactivation Of Bdnf-Trkb Signaling Cascades In Human Hypothalamic Hamartoma (Hh): A Potential Mechanism Contributing To Epileptogenesis, Suzan Semaan, Jie Wu, Yan Gan, Yu Jin, Guo Hui Li, John F. Kerrigan, Yong Chang, and Yao Huang

Amyotrophic Lateral Sclerosis: Is The Spinal Fluid Pathway Involved In Seeding And Spread?, Richard Smith, Kathleen Myers, John Ravits, and Robert Bowser

The effect of implant placement on sacroiliac joint range of motion: Posterior versus transarticular, Hector Soriano-Baron, Derek P. Lindsey, Nestor Rodriguez-Martinez, Phillip M. Reyes, Anna Newcomb, Scott A. Yerby, and Neil R. Crawford

High-Throughput Assay Development for Cystine-Glutamate Antiporter (xc-) Highlights Faster Cystine Uptake than Glutamate Release in Glioma Cells, Ajit G. Thomas, Rita Sattler, Karen Tendyke, Kara A. Loiacono, Hans Hansen, Vishal Sahni, Yutaka Hashizume, Camilo Rojas, and Barbara S. Slusher

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Amphiphilic cationic Zn-porphyrins with high photodynamic antimicrobial activity, Milini Thomas, James D. Craik, Artak Tovmasyan, Ines Batinic-Haberle, and Ludmil T. Benov

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α7 And β2 Nicotinic Acetylcholine Receptor Subunits Form Heteromeric Receptor Complexes That Are Expressed In The Human Cortex And Display Distinct Pharmacological Properties, Morten Skott Thomsen, Ruud Zwart, Daniel Ursu, Majbrit Myrup Jensen, Lars Hageman Pinborg, Gary Gilmour, Jie Wu, Emanuele Sher, and Jens Damsgaard Mikkelsen

A rare marginal tentorial artery to ophthalmic artery anastomosis, Daniel A. Tonetti, Ashutosh P. Jadhav, and Andrew F. Ducruet

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A comprehensive evaluation of catalase-like activity of different classes of redox-active therapeutics, Artak Tovmasyan, Clarissa G.C. Maia, Tin Weitner, Sebastián Carballal, Romulo S. Sampaio, Dominik Lieb, Robert Ghazaryan, Ivana Ivanovic-Burmazovic, Gerardo Ferrer-Sueta, Rafael Radi, Julio S. Reboucas, Ivan Spasojevic, Ludmil Benov, and Ines Batinic-Haberle

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Anticancer therapeutic potential of Mn porphyrin/ascorbate system, Artak Tovmasyan, Romulo S. Sampaio, Mary Keara Boss, Jacqueline C. Bueno-Janice, Bader H. Bader, Milini Thomas, Julio S. Reboucas, Michael Orr, Joshua D. Chandler, Young Mi Go, Dean P. Jones, Talaignair N. Venkatraman, Sinisa Haberle, Natalia Kyui, Christopher D. Lascola, Mark W. Dewhirst, Ivan Spasojevic, Ludmil Benov, and Ines Batinic-Haberle

Valproic acid treatment after experimental subarachnoid hemorrhage, Michael K. Tso, Elliot Lass, Jinglu Ai, and R. Loch Macdonald

Mouse models of hereditary hemorrhagic telangiectasia: Recent advances and future challenges, Simon Tual-Chalot, S. Paul Oh, and Helen M. Arthur

Chemical exchange in knee cartilage assessed by R1ρ (1/T1ρ) dispersion at 3T., Ping Wang, Jake Block, and John C Gore

Effects of flip angle uncertainty and noise on the accuracy of DCE-MRI metrics: comparison between standard concentration-based and signal difference methods., Ping Wang, Yiqun Xue, Xia Zhao, Jiangsheng Yu, Mark Rosen, and Hee Kwon Song

Evidence for a neuroprotective microRNA pathway in amnestic mild cognitive impairment, Rebecca B. Weinberg, Elliott J. Mufson, and Scott E. Counts

ESCAPE Trial Supports Rapid Endovascular Thrombectomy in the Management of Large-Vessel Acute Ischemic Stroke, Gregory M. Weiner and Andrew F. Ducruet

Mammalian target of rapamycin (mTOR) activity promotes neuronal survival in stroke with or without ischemic postconditioning, Gregory M. Weiner and Andrew F. Ducruet

The use of nanotechnology to improve the neuroprotective effects of adenosine in stroke and spinal cord injury, Gregory M. Weiner, Amir H. Faraji, and Andrew F. Ducruet

Radioprotection of the brain white matter by Mn(III) n-Butoxyethylpyridylporphyrin-based superoxide dismutase mimic MnTnBuOE-2-PyP5+, Douglas H. Weitzel, Artak Tovmasyan, Kathleen A. Ashcraft, Zrinka Rajic, Tin Weitner, Chunlei Liu, Wei Li, Anne F. Buckley, Mark R. Prasad, Kenneth H. Young, Ramona M. Rodriguiz, William C. Wetsel, Katherine B. Peters, Ivan Spasojevic, James E. Herndon, Ines Batinic-Haberle, and Mark W. Dewhirst

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Mechanisms Of Intrinsic Epileptogenesis In Human Gelastic Seizures With Hypothalamic Hamartoma, Jie Wu, Ming Gao, Jian Xin Shen, Shen Feng Qiu, and John F. Kerrigan

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Toxic Oligomeric Alpha-Synuclein Variants Present In Human Parkinson’S Disease Brains Are Differentially Generated In Mammalian Cell Models, Wei Xin, Sharareh Emadi, Stephanie Williams, Qiang Liu, Philip Schulz, Ping He, Now Bahar Alam, Jie Wu, and Michael R. Sierks

Therapeutically targeting tumor necrosis factor-α/ sphingosine-1-phosphate signaling corrects myogenic reactivity in subarachnoid hemorrhage, Kenji Yagi, Darcy Lidington, Hoyee Wan, Jessica C. Fares, Anja Meissner, Manabu Sumiyoshi, Jinglu Ai, Warren D. Foltz, Sergei A. Nedospasov, Stefan Offermanns, Shinji Nagahiro, R. Loch Macdonald, and Steffen Sebastian Bolz

The Coupling Interface And Pore Domain Codetermine The Single-Channel Activity Of The α7 Nicotinic Receptor, Hongxia Yan, Na Pan, Fenqin Xue, Yan Zheng, Chaokun Li, Yongchang Chang, Zhiqing Xu, Hui Yang, and Jianliang Zhang

Evaluation of genetic risk scores for prediction of dichotomous outcomes, Wonsuk Yoo, Selina A. Smith, and Steven S. Coughlin

The C9orf72 repeat expansion disrupts nucleocytoplasmic transport, Ke Zhang, Christopher J. Donnelly, Aaron R. Haeusler, Jonathan C. Grima, James B. Machamer, Peter Steinwald, Elizabeth L. Daley, Sean J. Miller, Kathleen M. Cunningham, Svetlana Vidensky, Saksham Gupta, Michael A. Thomas, Ingie Hong, Shu-Ling Chiu, Richard L. Huganir, Lyle W. Ostrow, Michael J. Matunis, Jiou Wang, Rita Sattler, Thomas E. Lloyd, and Jeffrey D. Rothstein

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Functional Impact Of 14 Single Nucleotide Polymorphisms Causing Missense Mutations Of Human α7 Nicotinic Receptor, Qinhui Zhang, Yingjie Du, Jianliang Zhang, Xiaojun Xu, Fenqin Xue, Cong Guo, Yao Huang, Ronald J. Lukas, and Yongchang Chang

Combination Of The Immune Modulator Fingolimod With Alteplase In Acute Ischemic Stroke: A Pilot Trial, Zilong Zhu, Ying Fu, Decai Tian, Na Sun, Wei Han, Guoqiang Chang, Yinhua Dong, Xiaolin Xu, Qiang Liu, Deren Huang, and Fu Dong Shi

Submissions from 2014

Mutant disrupted-in-schizophrenia 1 in astrocytes: focus on glutamate metabolism, Sofya Abazyan, Eun Ju Yang, Bagrat Abazyan, Meng Xia, Chunxia Yang, Camilo Rojas, Barbara Slusher, Rita Sattler, and Mikhail Pletnikov

Inhibition of adenosine kinase attenuates inflammation and neurotoxicity in traumatic optic neuropathy, Saif Ahmad, Nehal M. Elsherbiny, Kanchan Bhatia, Ahmed M. Elsherbini, Sadanand Fulzele, and Gregory I. Liou

Sesamin attenuates neurotoxicity in mouse model of ischemic brain stroke, Saif Ahmad, Nehal M. Elsherbiny, Rizwanul Haque, M. Badruzzaman Khan, Tauheed Ishrat, Zahoor A. Shah, Mohammad M. Khan, Mehboob Ali, Arshad Jamal, Deepshikha Pande Katare, Gregory I. Liou, and Kanchan Bhatia

Habb-e-Asgand, polyherbal Unani formulation, protects liver and antioxidative enzymes against paracetamol induced hepatotoxicity, Mehboob Ali, Sagheer Ahmed Khan, Peter S. Chang, Rizwanul Haque, Kanchan Bhatia, and Saif Ahmad

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Maternal choline supplementation improves spatial mapping and increases basal forebrain cholinergic neuron number and size in aged Ts65Dn mice, Jessica A. Ash, Ramon Velazquez, Christy M. Kelley, Brian E. Powers, Stephen D. Ginsberg, Elliott J. Mufson, and Barbara J. Strupp

Radiographic assessment of thoracolumbar fractures based on axial zones, Ali A. Baaj, Brian R. Gantwerker, Nicholas Theodore, Juan S. Uribe, Fernando L. Vale, Neil R. Crawford, and Volker K.H. Sonntag

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SOD therapeutics: latest insights into their structure-activity relationships and impact on the cellular redox-based signaling pathways, Ines Batinic-Haberle, Artak Tovmasyan, Emily R.H. Roberts, Zeljko Vujaskovic, Kam W. Leong, and Ivan Spasojevic

ALSUntangled no. 26: Lunasin, Richard Bedlack, Colin Quinn, Chafic Karam, Alex Sherman, Lyle Ostrow, Orla Hardiman, Terry Heiman-Patterson, Laurie Gutmann, Mark Bromberg, Gregory Carter, Edor Kabashi, Tulio Bertorini, Tahseen Mozaffar, Peter Andersen, Jeff Dietz, Josep Gamez, Mazen Dimachkie, Yunxia Wang, Paul Wicks, James Heywood, Steven Novella, L. P. Rowland, Erik Pioro, Lisa Kinsley, Kathy Mitchell, Jonathan Glass, Sith Sathornsumetee, Hubert Kwiecinski, Jon Baker, Nazem Atassi, and Dallas Forshew

Platelet-mediated changes to neuronal glutamate receptor expression at sites of microthrombosis following experimental subarachnoid hemorrhage: Laboratory investigation, Joshua D. Bell, Theresa Currier Thomas, Elliot Lass, Jinglu Ai, Hoyee Wan, Jonathan Lifshitz, Andrew J. Baker, and R. Loch MacDonald