The Barrow Neurological Institute is proud of its reputation as a medical research facility and is home to some of the most sophisticated research programs outside of an academic setting in the Southwestern United States. Researchers in the Barrow Neurosurgery Research Center are devoted to learning more about the causes of and treatments for a wide range of disorders, such as stroke, aneurysms, spinal cord injury, and hydrocephalus. Our research has led to treatments that are being used around the world. Within the Department are neurosurgeons who subspecialize in cerebrovascular and skull base, functional and stereotactic, pediatric, spine, tumor, and endovascular neurosurgery.
Physicians, scientists, and expert clinical staff come together with a commitment to developing new techniques for the prevention, diagnosis, treatment, and rehabilitation of neurological illnesses and injuries. The leadership of internationally respected physicians keeps Barrow at the forefront of neuroscience. The compassionate expertise of its extensive staff of nurses, technologists, therapists and support personnel is evident in every aspect of care provided.
Our mission is to advance the knowledge and practice of medicine in neuroscience through basic and clinical research, education of medical professionals, and innovation in clinical techniques and technology.
Submissions from 2018
Multisite Concordance Of Apparent Diffusion Coefficient Measurements Across The Nci Quantitative Imaging Network, David C. Newitt, Dariya Malyarenko, Thomas L. Chenevert, C. Chad Quarles, Laura Bell, Andriy Fedorov, Fiona Fennessy, Michael A. Jacobs, Meiyappan Solaiyappan, Stefanie Hectors, Bachir Taouli, Mark Muzi, Paul E. Kinahan, Kathleen M. Schmainda, Melissa A. Prah, Erin N. Taber, Christopher Kroenke, Wei Huang, Lori R. Arlinghaus, Thomas E. Yankeelov, Yue Cao, Madhava Aryal, Yi Fen Yen, Jayashree Kalpathy-Cramer, Amita Shukla-Dave, Maggie Fung, Jiachao Liang, Michael Boss, and Nola Hylton
α1-Fangs: Protein Ligands Selective For The α-Bungarotoxin Site Of The α1-Nicotinic Acetylcholine Receptor, Aaron L. Nichols, Kaori Noridomi, Christopher R. Hughes, Farzad Jalali-Yazdi, J. Brek Eaton, Lan Huong Lai, Gaurav Advani, Ronald J. Lukas, Henry A. Lester, Lin Chen, and Richard W. Roberts
Genome-Wide Analyses Identify Kif5A As A Novel Als Gene, Aude Nicolas, Kevin P. Kenna, Alan E. Renton, Nicola Ticozzi, Faraz Faghri, Ruth Chia, Janice A. Dominov, Brendan J. Kenna, Mike A. Nalls, Pamela Keagle, Alberto M. Rivera, Wouter van Rheenen, Natalie A. Murphy, Joke J.F.A. van Vugt, Joshua T. Geiger, Rick A. Van der Spek, Hannah A. Pliner, Shankaracharya, Bradley N. Smith, Giuseppe Marangi, Simon D. Topp, Yevgeniya Abramzon, Athina Soragia Gkazi, John D. Eicher, Aoife Kenna, Francesco O. Logullo, Isabella L. Simone, Giancarlo Logroscino, Fabrizio Salvi, Ilaria Bartolomei, Giuseppe Borghero, Maria Rita Murru, Emanuela Costantino, Carla Pani, Roberta Puddu, Carla Caredda, Valeria Piras, Stefania Tranquilli, Stefania Cuccu, Daniela Corongiu, Maurizio Melis, Antonio Milia, Francesco Marrosu, Maria Giovanna Marrosu, Gianluca Floris, Antonino Cannas, Margherita Capasso, Claudia Caponnetto, Gianluigi Mancardi, Paola Origone, and Robert Bowser
Nf-κb Inhibition Rescues Cardiac Function By Remodeling Calcium Genes In A Duchenne Muscular Dystrophy Model, Jennifer M. Peterson, David J. Wang, Vikram Shettigar, Steve R. Roof, Benjamin D. Canan, Nadine Bakkar, Jonathan Shintaku, Jin Mo Gu, Sean C. Little, Nivedita M. Ratnam, Priya Londhe, Leina Lu, Christopher E. Gaw, Jennifer M. Petrosino, Sandya Liyanarachchi, Huating Wang, Paul M.L. Janssen, Jonathan P. Davis, Mark T. Ziolo, Sudarshana M. Sharma, and Denis C. Guttridge
The Molecular Mechanism Of Alpha-Synuclein Dependent Regulation Of Protein Phosphatase 2A Activity, Jing Qu, Hongxia Yan, Yuan Zheng, Fenqin Xue, Yan Zheng, Hongjuan Fang, Yongchang Chang, Hui Yang, and Jianliang Zhang
Glycomic and proteomic changes in aging brain nigrostriatal pathway, Rekha Raghunathan, Nicole K. Polinski, Joshua Klein, John D. Hogan, Chun Shao, Kshitij Khatri, Deborah Leon, Mark E. McComb, Fredric P. Manfredsson, Caryl E. Sortwell, and Joseph Zaia
Selective Disruption Of Tlr2-Myd88 Interaction Inhibits Inflammation And Attenuates Alzheimer'S Pathology, Suresh B. Rangasamy, Malabendu Jana, Avik Roy, Grant T. Corbett, Madhuchhanda Kundu, Sujyoti Chandra, Susanta Mondal, Sridevi Dasarathi, Elliott J. Mufson, Rama K. Mishra, Chi Hao Luan, David A. Bennett, and Kalipada Pahan
Selective Nlrp3 (Pyrin Domain-Containing Protein 3) Inflammasome Inhibitor Reduces Brain Injury After Intracerebral Hemorrhage, Honglei Ren, Ying Kong, Zhijia Liu, Dongyun Zang, Xiaoxia Yang, Kristofer Wood, Minshu Li, and Qiang Liu
Phase 0 Trial of AZD1775 in First-Recurrence Glioblastoma Patients, Nader Sanai, Jing Li, Julie Boerner, Karri Stark, Jianmei Wu, Seongho Kim, Alanna Derogatis, Shwetal Mehta, Harshil D. Dhruv, Lance K. Heilbrun, Michael E. Berens, and Patricia M. LoRusso
Multisite Concordance Of Dsc-Mri Analysis For Brain Tumors: Results Of A National Cancer Institute Quantitative Imaging Network Collaborative Project, K. M. Schmainda, M. A. Prah, S. D. Rand, Y. Liu, B. Logan, M. Muzi, S. D. Rane, X. Da, Y. F. Yen, J. Kalpathy-Cramer, T. L. Chenevert, B. Hoff, B. Ross, Y. Cao, M. P. Aryal, B. Erickson, P. Korfiatis, T. Dondlinger, L. Bell, L. Hu, P. E. Kinahan, and C. C. Quarles
Optimization Of Acquisition And Analysis Methods For Clinical Dynamic Susceptibility Contrast Mri Using A Population-Based Digital Reference Object, N. B. Semmineh, L. C. Bell, A. M. Stokes, L. S. Hu, J. L. Boxerman, and C. C. Quarles
Cyclic-GMP-elevating agents suppress polyposis in Apc Min mice by targeting the preneoplastic epithelium, Sarah K. Sharman, Bianca N. Islam, Yali Hou, Nagendra Singh, Franklin G. Berger, Subbaramiah Sridhar, Wonsuk Yoo, and Darren D. Browning
Venous sinus stenting shortens the duration of medical therapy for increased intracranial pressure secondary to venous sinus stenosis, Tarek A. Shazly, Ashutosh P. Jadhav, Amin Aghaebrahim, Andrew F. Ducruet, Brian T. Jankowitz, Tudor G. Jovin, and Gabrielle R. Bonhomme
Stroke-Induced Immunosuppression And Poststroke Infection, Kaibin Shi, Kristofer Wood, Fu Dong Shi, Xiaoying Wang, and Qiang Liu
Mitochondrial ROS cause motor deficits induced by synaptic inactivity: Implications for synapse pruning, Eva Sidlauskaite, Jack W. Gibson, Ian L. Megson, Philip D. Whitfield, Artak Tovmasyan, Ines Batinic-Haberle, Michael P. Murphy, Peter R. Moult, and James N. Cobley
Determinants of adherence to physical activity guidelines among overweight and obese African American breast cancer survivors: Implications for an intervention approach, Selina A. Smith, Benjamin E. Ansa, Wonsuk Yoo, Mary S. Whitehead, and Steven S. Coughlin
Biomechanical Analysis Of An Expandable Lumbar Interbody Spacer, Hector Soriano-Baron, Anna G.U.S. Newcomb, Devika Malhotra, Atilio E. Palma, Eduardo Martinez-del-Campo, Neil R. Crawford, Nicholas Theodore, Brian P. Kelly, and Taro Kaibara
Synaptic Dysfunction And Altered Excitability In C9Orf72 Als/Ftd, Alexander Starr and Rita Sattler
Biomechanical evaluation of the ProDisc-C stability following graded posterior cervical injury, Michael D. Staudt, Doron Rabin, Ali A. Baaj, Neil R. Crawford, and Neil Duggal
α6 Subunit-Containing Nicotinic Receptors Mediate Low-Dose Ethanol Effects On Ventral Tegmental Area Neurons And Ethanol Reward, Scott C. Steffensen, Samuel I. Shin, Ashley C. Nelson, Stephanie S. Pistorius, Stephanie B. Williams, Taylor J. Woodward, Hyun Jung Park, Lindsey Friend, Ming Gao, Fenfei Gao, Devin H. Taylor, M. Foster Olive, Jeffrey G. Edwards, Sterling N. Sudweeks, Lori M. Buhlman, J. Michael McIntosh, and Jie Wu
Fingolimod Enhances the Efficacy of Delayed Alteplase Administration in Acute Ischemic Stroke by Promoting Anterograde Reperfusion and Retrograde Collateral Flow, De Cai Tian, Kaibin Shi, Zilong Zhu, Jia Yao, Xiaoxia Yang, Lei Su, Sheng Zhang, Meixia Zhang, Rayna J. Gonzales, Qiang Liu, De Ren Huang, Michael F. Waters, Kevin N. Sheth, Andrew F. Ducruet, Ying Fu, Min Lou, and Fu-Dong Shi
Pretangle pathology within cholinergic nucleus basalis neurons coincides with neurotrophic and neurotransmitter receptor gene dysregulation during the progression of Alzheimer's disease, Chelsea T. Tiernan, Stephen D. Ginsberg, Bin He, Sarah M. Ward, Angela L. Guillozet-Bongaarts, Nicholas M. Kanaan, Elliott J. Mufson, and Scott E. Counts
Tau oligomer pathology in nucleus basalis neurons during the progression of Alzheimer Disease, Chelsea T. Tiernan, Elliott J. Mufson, Nicholas M. Kanaan, and Scott E. Counts
Radiation-Mediated Tumor Growth Inhibition Is Significantly Enhanced with Redox-Active Compounds That Cycle with Ascorbate, Artak Tovmasyan, Jacqueline C. Bueno-Janice, Melba C. Jaramillo, Romulo S. Sampaio, Julio S. Reboucas, Natalia Kyui, Ludmil Benov, Brian Deng, Ting Ting Huang, Margaret E. Tome, Ivan Spasojevic, and Ines Batinic-Haberle
Hemodynamic Markers in the Anterior Circulation as Predictors of Recurrent Stroke in Patients With Intracranial Stenosis, Ashley M. Wabnitz, Colin P. Derdeyn, David J. Fiorella, Michael J. Lynn, George A. Cotsonis, David S. Liebeskind, Michael F. Waters, Helmi Lutsep, Elena López-Cancio, Tanya N. Turan, Jean Montgomery, L Scott Janis, Bethany Lane, and Marc I. Chimowitz
Ischemia-induced Neuronal Cell Death Is Mediated by Chemokine Receptor CX3CR1, Jinkun Wang, Yan Gan, Pengcheng Han, Junxiang Yin, Qingwei Liu, Soha Ghanian, Feng Gao, Guanghui Gong, and Zhiwei Tang
C/EBPβ regulates delta-secretase expression and mediates pathogenesis in mouse models of Alzheimer's disease, Zhi-Hao Wang, Ke Gong, Xia Liu, Zhentao Zhang, Xiaoou Sun, Zheng Zachory Wei, Shan Ping Yu, Fredric P. Manfredsson, Ivette M. Sandoval, Peter F. Johnson, Jianping Jia, Jian-Zhi Wang, and Keqiang Ye
BDNF inhibits neurodegenerative disease-associated asparaginyl endopeptidase activity via phosphorylation by AKT, Zhi Hao Wang, Wanqiang Wu, Seong Su Kang, Xia Liu, Zhiping Wu, Junmin Peng, Shan Ping Yu, Fredric P. Manfredsson, Ivette M. Sandoval, Xuebo Liu, Jian Zhi Wang, and Keqiang Ye
Role of von Willebrand factor and ADAMTS-13 in early brain injury after experimental subarachnoid hemorrhage, H. Wan, Y. Wang, J. Ai, S. Brathwaite, H. Ni, R. L. Macdonald, E. M. Hol, J. C.M. Meijers, and M. D.I. Vergouwen
A multicenter study evaluating the frequency and time requirement of mechanical thrombectomy, Taylor A. Wilson, Thabele Leslie-Mazwi, Joshua A. Hirsch, Casey Frey, Teddy E. Kim, Alejandro M. Spiotta, Reade de Leacy, J Mocco, Felipe C. Albuquerque, Andrew F. Ducruet, Ahmed Cheema, Adam Arthur, Visish M. Srinivasan, Peter Kan, Maxim Mokin, Travis Dumont, Ansaar Rai, Jasmeet Singh, Stacey Q. Wolfe, and Kyle M. Fargen
The Effects Of Intravoxel Contrast Agent Diffusion On The Analysis Of Dce-Mri Data In Realistic Tissue Domains, Ryan T. Woodall, Stephanie L. Barnes, David A. Hormuth, Anna G. Sorace, C. Chad Quarles, and Thomas E. Yankeelov
Depletion Of Microglia Augments The Dopaminergic Neurotoxicity Of Mptp, Xiaoxia Yang, Honglei Ren, Kristofer Wood, Minshu Li, Shenfeng Qiu, Fu Dong Shi, Cungen Ma, and Qiang Liu
DNAJ Proteins in neurodegeneration: essential and protective factors, Christina Zarouchlioti, David A. Parfitt, Wenwen Li, Lauren M. Gittings, and Michael E. Cheetham
Novel DNA Aptamers for Parkinson’s Disease Treatment Inhibit a-Synuclein Aggregation and Facilitate its Degradation, Yuan Zheng, Jing Qu, Fenqin Xue, Yan Zheng, Bo Yang, Yongchang Chang, Hui Yang, and Jianliang Zhang
Technique: Open lumbar decompression and fusion with the Excelsius GPS robot, Corinna C. Zygourakis, A. Karim Ahmed, Samuel Kalb, Alex M. Zhu, Ali Bydon, Neil R. Crawford, and Nicholas Theodore
Submissions from 2017
Streamlining door to recanalization processes in endovascular stroke therapy, Amin Aghaebrahim, Christopher Streib, Srikant Rangaraju, Cynthia L. Kenmuir, Dan-Victor Giurgiutiu, Anat Horev, Yumna Saeed, Clifton W. Callaway, Francis X. Guyette, Chris Martin-Gill, Charissa Pacella, Andrew F. Ducruet, Brian T. Jankowitz, Tudor G. Jovin, and Ashutosh P. Jadhav
Management of Iatrogenic Direct Carotid Cavernous Fistula Occurring During Endovascular Treatment of Stroke, Nima Alan, Enyinna Nwachuku, Tudor J. Jovin, Brian T. Jankowitz, Ashutosh P. Jadhav, and Andrew F. Ducruet
Optimizing Zn porphyrin-based photosensitizers for efficient antibacterial photodynamic therapy, Khazna Alenezi, Artak Tovmasyan, Ines Batinic-Haberle, and Ludmil T. Benov
ALSUntangled No. 36: Accilion, Richard Bedlack, Emma Fixsen, Colin Quinn, Chafic Karam, Alex Sherman, Lyle Ostrow, Orla Hardiman, Terry Heiman-Patterson, Laurie Gutmann, Mark Bromberg, Gregory Carter, Edor Kabashi, Tulio Bertorini, Tahseen Mozaffar, Peter Andersen, Josep Gamez, Mazen Dimachkie, Yunxia Wang, Paul Wicks, James Heywood, Steven Novella, L. P. Rowland, Erik Pioro, Lisa Kinsley, Kathy Mitchell, Jonathan Glass, Sith Sathornsumetee, Jon Baker, Nazem Atassi, Dallas Forshew, John Ravits, and Robin Conwit
Characterizing the Influence of Preload Dosing on Percent Signal Recovery (PSR) and Cerebral Blood Volume (CBV) Measurements in a Patient Population With High-Grade Glioma Using Dynamic Susceptibility Contrast MRI, Laura C. Bell, Leland S. Hu, Ashley M. Stokes, Samuel C. McGee, Leslie C. Baxter, and C. Chad Quarles
Optimization Of Dsc Mri Echo Times For Cbv Measurements Using Error Analysis In A Pilot Study Of High-Grade Gliomas, L. C. Bell, M. D. Does, A. M. Stokes, L. C. Baxter, K. M. Schmainda, A. C. Dueck, and C. C. Quarles
ALS Associated Mutations In Matrin 3 Alter Protein-Protein Interactions And Impede Mrna Nuclear Export, Ashley Boehringer, Krystine Garcia-Mansfield, Gurkaran Singh, Nadine Bakkar, Patrick Pirrotte, and Robert Bowser
Correlating Resting-State Functional Magnetic Resonance Imaging Connectivity by Independent Component Analysis-Based Epileptogenic Zones with Intracranial Electroencephalogram Localized Seizure Onset Zones and Surgical Outcomes in Prospective Pediatric Intractable Epilepsy Study, Varina L. Boerwinkle, Deepankar Mohanty, Stephen T. Foldes, Danielle Guffey, Charles G. Minard, Aditya Vedantam, Jeffrey S. Raskin, Sandi Lam, Margaret Bond, Lucia Mirea, P David Adelson, Angus A. Wilfong, and Daniel J. Curry
Potential for a novel manganese porphyrin compound as adjuvant canine lymphoma therapy, M. K. Boss, M. W. Dewhirst, R. S. Sampaio, A. Bennett, A. Tovmasyan, K. G. Berman, A. W. Beaven, D. A. Rizzieri, I. Batinic-Haberle, M. L. Hauck, and I. Spasojevic
ALSUntangled 39: Acuscope (micro-Amp electrical muscle stimulation)., Robert Bowser and ALSUntangled Group
ALSUntangled 40: Ayahuasca., Robert Bowser and ALSUntangled Group
Mir-223 regulates the number and function of myeloid-derived suppressor cells in multiple sclerosis and experimental autoimmune encephalomyelitis, Claudia Cantoni, Francesca Cignarella, Laura Ghezzi, Bob Mikesell, Bryan Bollman, Melissa M. Berrien-Elliott, Aaron R. Ireland, Todd A. Fehniger, Gregory F. Wu, and Laura Piccio
Post-illumination cellular effects of photodynamic treatment, Malak Charara, Artak Tovmasyan, Ines Batinic-Haberle, James Craik, and Ludmil Benov
Brain Cannabinoid Receptor 2: Expression Function And Modulation, De Jie Chen, Ming Gao, Fen Fei Gao, Quan Xi Su, and Jie Wu
Biomechanical comparison of same size transfacet screws versus pedicle screws across the L5-S1 native disc, K. R. Chin, F. J.R. Pencle, A. G.U. Newcomb, M. T. Reis, P. M. Reyes, D. Malhotra, W. D. Yu, C. A. Bruce, and N. R. Crawford
Corrigendum: Mitochondrial ATP transporter depletion protects mice against liver steatosis and insulin resistance, Joonseok Cho, Yujian Zhang, Shi Young Park, Anna Maria Joseph, Chul Han, Hyo Jin Park, Srilaxmi Kalavalapalli, Sung Kook Chun, Drake Morgan, Jae Sung Kim, Shinichi Someya, Clayton E. Mathews, Young Jae Lee, Stephanie E. Wohlgemuth, Nishanth E. Sunny, Hui Young Lee, Cheol Soo Choi, Takayuki Shiratsuchi, S. Paul Oh, and Naohiro Terada
Mitochondrial ATP transporter depletion protects mice against liver steatosis and insulin resistance, Joonseok Cho, Yujian Zhang, Shi Young Park, Anna Maria Joseph, Chul Han, Hyo Jin Park, Srilaxmi Kalavalapalli, Sung Kook Chun, Drake Morgan, Jae Sung Kim, Shinichi Someya, Clayton E. Mathews, Young Jae Lee, Stephanie E. Wohlgemuth, Nishanth E. Sunny, Hui Young Lee, Cheol Soo Choi, Takayuki Shiratsuchi, S. Paul Oh, and Naohiro Terada
Molecular Mechanisms of Amyotrophic Lateral Sclerosis, M. Collins and R. Bowser
Patient web portals, disease management, and primary prevention, Steven S. Coughlin, Judith J. Prochaska, Lovoria B. Williams, Gina M. Besenyi, Vahé Heboyan, D. Stephen Goggans, Wonsuk Yoo, and Gianluca De Leo
Biomarkers For The Early Detection And Progression Of Alzheimer’S Disease, Scott E. Counts, Milos D. Ikonomovic, Natosha Mercado, Irving E. Vega, and Elliott J. Mufson
Regulator Of Cell Cycle (Rgcc) Expression During The Progression Of Alzheimer's Disease, Scott E. Counts and Elliott J. Mufson
Post-Transcriptional Inhibition Of Hsc70-4/Hspa8 Expression Leads To Synaptic Vesicle Cycling Defects In Multiple Models Of Als, Alyssa N. Coyne, Ileana Lorenzini, Ching Chieh Chou, Meaghan Torvund, Robert S. Rogers, Alexander Starr, Benjamin L. Zaepfel, Jennifer Levy, Jeffrey Johannesmeyer, Jacob C. Schwartz, Hiroshi Nishimune, Konrad Zinsmaier, Wilfried Rossoll, Rita Sattler, and Daniela C. Zarnescu
Atypical Teratoid Rhabdoid Tumor: two Case Reports and an Analysis of Adult Cases With Implications for Pathophysiology and Treatment, Christopher Dardis, Jared Yeo, Kelly Milton, Lynn S. Ashby, Kris A. Smith, Shwetal Mehta, Emad Youssef, Jenny Eschbacher, Kathy Tucker, Laughlin Dawes, Neil Lambie, Elizabeth Algar, and Elizabeth Hovey
Tissue sodium accumulation and peripheral insulin sensitivity in maintenance hemodialysis patients., Serpil Muge Deger, Ping Wang, Rachel Fissell, Charles D Ellis, Cindy Booker, Feng Sha, Jennifer L Morse, Thomas G Stewart, John C Gore, Edward D Siew, Jens Titze, and Talat Alp Ikizler
Aged Chimpanzees Exhibit Pathologic Hallmarks Of Alzheimer'S Disease, Melissa K. Edler, Chet C. Sherwood, Richard S. Meindl, William D. Hopkins, John J. Ely, Joseph M. Erwin, Elliott J. Mufson, Patrick R. Hof, and Mary Ann Raghanti
Immediate Label-Free Ex Vivo Evaluation of Human Brain Tumor Biopsies With Confocal Reflectance Microscopy, Jennifer M. Eschbacher, Joseph F. Georges, Evgenii Belykh, Mohammedhassan Izady Yazdanabadi, Nikolay L. Martirosyan, Emily Szeto, Catherine Y. Seiler, Michael A. Mooney, Jessica K. Daniels, Katherine Y. Goehring, Kendall R. Van Keuren-Jensen, Mark C. Preul, Stephen W. Coons, Shwetal Mehta, and Peter Nakaji
Social media and JNIS: Expanding the digital clique, Kyle M. Fargen, Taylor A. Wilson, Reade De Leacy, Ashutosh P. Jadhav, and Andrew F. Ducruet
Infiltration And Persistence Of Lymphocytes During Late-Stage Cerebral Ischemia In Middle Cerebral Artery Occlusion And Photothrombotic Stroke Models, Yan Feng, Shiwei Liao, Changjuan Wei, Dongmei Jia, Kristofer Wood, Qiang Liu, Xiaoying Wang, Fu Dong Shi, and Wei Na Jin
Negative Impact Of Female Sex On Outcomes From Repetitive Mild Traumatic Brain Injury In Htau Mice Is Age Dependent: A Chronic Effects Of Neurotrauma Consortium Study, Scott A. Ferguson, Benoit C. Mouzon, Cillian Lynch, Carlyn Lungmus, Alexander Morin, Gogce Crynen, Benjamin Carper, Gayle Bieler, Elliott J. Mufson, William Stewart, Michael Mullan, and Fiona Crawford
Abnormal Expression Of Homeobox Genes And Transthyretin In C9Orf72 Expansion Carriers, Nicole A. Finch, Xue Wang, Matthew C. Baker, Michael G. Heckman, Tania F. Gendron, Kevin F. Bieniek, Joanne Wuu, Mariely Dejesus-Hernandez, Patricia H. Brown, Jeannie Chew, Karen R. Jansen-West, Lillian M. Daughrity, Alexandra M. Nicholson, Melissa E. Murray, Keith A. Josephs, Joseph E. Parisi, David S. Knopman, Ronald C. Petersen, Leonard Petrucelli, Bradley F. Boeve, Neill R. Graff-Radford, Yan W. Asmann, Dennis W. Dickson, Michael Benatar, Robert Bowser, Kevin B. Boylan, Rosa Rademakers, and Marka Van Blitterswijk
Subthalamic Nucleus Deep Brain Stimulation Does Not Modify the Functional Deficits or Axonopathy Induced by Nigrostriatal α-Synuclein Overexpression, D. Luke Fischer, Fredric P. Manfredsson, Christopher J. Kemp, Allyson Cole-Strauss, Jack W. Lipton, Megan F. Duffy, Nicole K. Polinski, Kathy Steece-Collier, Timothy J. Collier, Sara E. Gombash, Daniel J. Buhlinger, and Caryl E. Sortwell
Can STN DBS protect both nigral somata and innervation of the striatum?, D. Luke Fischer, Fredric P. Manfredsson, and Caryl E. Sortwell
Altered modulation of sensorimotor rhythms with chronic paralysis, Stephen T. Foldes, Douglas J. Weber, and Jennifer L. Collinger
Deregulation of ZPR1 causes respiratory failure in spinal muscular atrophy, Naresh K. Genabai, Annapoorna Kannan, Saif Ahmad, Xiaoting Jiang, Kanchan Bhatia, and Laxman Gangwani
Poly(Gp) Proteins Are A Useful Pharmacodynamic Marker For C9Orf72-Associated Amyotrophic Lateral Sclerosis, Tania F. Gendron, Jeannie Chew, Jeannette N. Stankowski, Lindsey R. Hayes, Yong Jie Zhang, Mercedes Prudencio, Yari Carlomagno, Lillian M. Daughrity, Karen Jansen-West, Emilie A. Perkerson, Aliesha O'Raw, Casey Cook, Luc Pregent, Veronique Belzil, Marka Van Blitterswijk, Lilia J. Tabassian, Chris W. Lee, Mei Yue, Jimei Tong, Yuping Song, Monica Castanedes-Casey, Linda Rousseau, Virginia Phillips, Dennis W. Dickson, Rosa Rademakers, John D. Fryer, Beth K. Rush, Otto Pedraza, Ana M. Caputo, Pamela Desaro, Carla Palmucci, Amelia Robertson, Michael G. Heckman, Nancy N. Diehl, Edythe Wiggs, Michael Tierney, Laura Braun, Jennifer Farren, David Lacomis, Shafeeq S. Ladha, Christina N. Fournier, Leo F. McCluskey, Lauren B. Elman, Jon B. Toledo, Jennifer D. McBride, Cinzia Tiloca, Claudia Morelli, Barbara Poletti, Federica Solca, Alessandro Prelle, and Robert Bowser
Phosphorylated neurofilament heavy chain: A biomarker of survival for C9ORF72-associated amyotrophic lateral sclerosis, Tania F. Gendron, Lillian M. Daughrity, Michael G. Heckman, Nancy N. Diehl, Joanne Wuu, Timothy M. Miller, Pau Pastor, John Q. Trojanowski, Murray Grossman, James D. Berry, William T. Hu, Antonia Ratti, Michael Benatar, Vincenzo Silani, Jonathan D. Glass, Mary Kay Floeter, Andreas Jeromin, Kevin B. Boylan, Leonard Petrucelli, Mercedes Prudencio, Ana M. Caputo, Pamela Desaro, Carla Palmucci, Amelia Robertson, Yuping Song, Beth K. Rush, Otto Pedraza, David Lacomis, Shafeeq Ladha, Christina N. Fournier, Leo F. McCluskey, and Lauren B. Elman
Isoform-Specific Mechanisms Of A3β4ˆ—-Nicotinic Acetylcholine Receptor Modulation By The Prototoxin Lynx1, Andrew A. George, Abigail Bloy, Julie M. Miwa, Jon M. Lindstrom, Ronald J. Lukas, and Paul Whiteaker
Biomechanical And Endplate Effects On Nutrient Transport In The Intervertebral Disc, Morgan B. Giers, Bryce T. Munter, Kyle J. Eyster, George D. Ide, Anna G.U.S. Newcomb, Jennifer N. Lehrman, Evgenii Belykh, Vadim A. Byvaltsev, Brian P. Kelly, Mark C. Preul, and Nicholas Theodore
"Molecular" MR imaging at high fields., John C Gore, Zhongliang Zu, Ping Wang, Hua Li, Junzhong Xu, Richard Dortch, and Daniel F Gochberg
An Intraoperative Look at a Residual/Recurrent Tentorial Dural Arteriovenous Fistula, Bradley A. Gross, Andrew F. Ducruet, Brian T. Jankowitz, and Paul A. Gardner
Neuronal Exosomes Reveal Alzheimer'S Disease Biomarkers In Down Syndrome, Eric D. Hamlett, Edward J. Goetzl, Aurélie Ledreux, Vitaly Vasilevko, Heather A. Boger, Angela LaRosa, David Clark, Steven L. Carroll, MarÃa Carmona-Iragui, Juan Fortea, Elliott J. Mufson, Marwan Sabbagh, Abdul H. Mohammed, Dean Hartley, Eric Doran, Ira T. Lott, and Ann Charlotte Granholm
Non-Neuronal Cholinergic Activity Is Potentiated In Myasthenia Gravis, Bin Han, Chao Zhang, Shoufeng Liu, Yiping Xia, Hao Sun, Zhongying Gong, Alain R. Simard, Qiang Liu, and Junwei Hao
HIF1A in aortic aneurysms and beyond, Tomoki Hashimoto and Victor Rizzo
Cathepsin K cleavage of SDF-1α inhibits its chemotactic activity towards glioblastoma stem-like cells, Vashendriya V. Hira, Urška Verbovšek, Barbara Breznik, Matic Srdič, Marko Novinec, Hala Kakar, Jill Wormer, Britt Van der Swaan, Brigita Lenarčič, Luiz Juliano, Shwetal Mehta, Cornelis J. Van Noorden, and Tamara T. Lah
Human perception of electrical stimulation on the surface of somatosensory cortex, Shivayogi V. Hiremath, Elizabeth C. Tyler-Kabara, Jesse J. Wheeler, Daniel W. Moran, Robert A. Gaunt, Jennifer L. Collinger, Stephen T. Foldes, Douglas J. Weber, Weidong Chen, Michael L. Boninger, and Wei Wang
JNIS podcasts: the early part of our journey, Joshua A. Hirsch, Kyle Fargen, Andrew F. Ducruet, and Robert W. Tarr
Pics In Motoneurons Do Not Scale With The Size Of The Animal: A Possible Mechanism For Faster Speed Of Muscle Contraction In Smaller Species, Seoan Huh, Ramamurthy Siripuram, Robert H. Lee, Vladimir V. Turkin, Derek O’Neill, Thomas M. Hamm, Charles J. Heckman, and Marin Manuel
Radiogenomics To Characterize Regional Genetic Heterogeneity In Glioblastoma, Leland S. Hu, Shuluo Ning, Jennifer M Eschbacher, Leslie C. Baxter, Nathan Gaw, Sara Ranjbar, Jonathan Plasencia, Amylou C. Dueck, Sen Peng, Kris A Smith, Peter Nakaji, John P Karis, C. Chad Quarles, Teresa Wu, Joseph C. Loftus, Robert B. Jenkins, Hugues Sicotte, Thomas M. Kollmeyer, Brian P. O'Neill, William Elmquist, Joseph M. Hoxworth, David Frakes, Jann Sarkaria, Kristin R. Swanson, Nhan L. Tran, Jing Li, and J. Ross Mitchell
Stent Retriever-Mediated Manual Aspiration Thrombectomy for Acute Ischemic Stroke, Ashutosh P. Jadhav, Amin Aghaebrahim, Anat Horev, Dan-Victor Giurgiutiu, Andrew F. Ducruet, Brian Jankowitz, and Tudor G. Jovin
Interfacility Transfer Directly to the Neuroangiography Suite in Acute Ischemic Stroke Patients Undergoing Thrombectomy, Ashutosh P. Jadhav, Cynthia L. Kenmuir, Amin Aghaebrahim, Kaustubh Limaye, Lawrence R. Wechsler, Maxim D. Hammer, Matthew T. Starr, Bradley J. Molyneaux, Marcelo Rocha, Francis X. Guyette, Christian Martin-Gill, Andrew F. Ducruet, Bradley A. Gross, Brian T. Jankowitz, and Tudor G. Jovin
Biomarkers in Neurodegenerative Diseases, Andreas Jeromin and Robert Bowser
Acetylcholine-Producing Nk Cells Attenuate Cns Inflammation Via Modulation Of Infiltrating Monocytes/Macrophages, Wei Jiang, Daojing Li, Ranran Han, Chao Zhang, Wei Na Jin, Kristofer Wood, Qiang Liu, Fu Dong Shi, and Junwei Hao
Depletion Of Microglia Exacerbates Postischemic Inflammation And Brain Injury, Wei Na Jin, Samuel Xiang Yu, Zhiguo Li, Minshu Li, Kristofer Wood, Rayna J. Gonzales, and Qiang Liu
Rotational Vertebral Artery Dissection Secondary to Anomalous Entrance into Transverse Foramen, Stephen A. Johnson, Andrew F. Ducruet, Jonathan B. Bellotte, Charles E. Romero, and Robert M. Friedlander
Rationally Engineered AAV Capsids Improve Transduction and Volumetric Spread in the CNS, Nicholas M. Kanaan, Rhyomi C. Sellnow, Sanford L. Boye, Ben Coberly, Antonette Bennett, Mavis Agbandje-McKenna, Caryl E. Sortwell, William W. Hauswirth, Shannon E. Boye, and Fredric P. Manfredsson
TrkB neurotrophic activities are blocked by α-synuclein, triggering dopaminergic cell death in Parkinson’s disease, Seong Su Kang, Zhentao Zhang, Xia Liu, Fredric P. Manfredsson, Matthew J. Benskey, Xuebing Cao, Jun Xu, Yi E. Sun, and Keqiang Ye
α-Synuclein binds and sequesters PIKE-L into Lewy bodies, triggering dopaminergic cell death via AMPK hyperactivation, Seong Su Kang, Zhentao Zhang, Xia Liu, Fredric P. Manfredsson, Li He, P. Michael Iuvone, Xuebing Cao, Yi E. Sun, Lingjing Jin, and Keqiang Ye
Vascular ADAM17 (a Disintegrin and Metalloproteinase Domain 17) Is Required for Angiotensin II/β-Aminopropionitrile-Induced Abdominal Aortic Aneurysm, Tatsuo Kawai, Takehiko Takayanagi, Steven J. Forrester, Kyle J. Preston, Takashi Obama, Toshiyuki Tsuji, Tomonori Kobayashi, Michael J. Boyer, Hannah A. Cooper, Hang Fai Kwok, Tomoki Hashimoto, Rosario Scalia, Victor Rizzo, and Satoru Eguchi
Locus coeruleus cellular and molecular pathology during the progression of Alzheimer's disease, Sarah C. Kelly, Bin He, Sylvia E. Perez, Stephen D. Ginsberg, Elliott J. Mufson, and Scott E. Counts
Hypothalamic Hamartoma: Neuropathology And Epileptogenesis, John F. Kerrigan, Angela Parsons, Candy Tsang, Kristina Simeone, Stephen Coons, and Jie Wu
CXCL12-CXCR4 signalling plays an essential role in proper patterning of aortic arch and pulmonary arteries, Bo Gyeong Kim, Yong Hwan Kim, Edward L. Stanley, Eva M. Garrido-Martin, Young Jae Lee, and S. Paul Oh
Systemic levels of estrogens and PGE2 synthesis in relation to postmenopausal breast cancer risk, Sangmi Kim, Jeff Campbell, Wonsuk Yoo, Jack A. Taylor, and Dale P. Sandler
Selective effects of oral antiangiogenic tyrosine kinase inhibitors on an animal model of hereditary hemorrhagic telangiectasia., Y H Kim, M-J Kim, S-W Choe, D Sprecher, Y J Lee, and S P Oh
Selective effects of oral antiangiogenic tyrosine kinase inhibitors on an animal model of hereditary hemorrhagic telangiectasia, Y. H. Kim, M. J. Kim, S. W. Choe, D. Sprecher, Y. J. Lee, and S. P. Oh
Harnessing OLIG2 function in tumorigenicity and plasticity to target malignant gliomas, Jennifer Kosty, Fanghui Lu, Robert Kupp, Shwetal Mehta, and Q. Richard Lu