The Barrow Neurological Institute is proud of its reputation as a medical research facility and is home to some of the most sophisticated research programs outside of an academic setting in the Southwestern United States. Researchers in the Barrow Neurosurgery Research Center are devoted to learning more about the causes of and treatments for a wide range of disorders, such as stroke, aneurysms, spinal cord injury, and hydrocephalus. Our research has led to treatments that are being used around the world. Within the Department are neurosurgeons who subspecialize in cerebrovascular and skull base, functional and stereotactic, pediatric, spine, tumor, and endovascular neurosurgery.

Physicians, scientists, and expert clinical staff come together with a commitment to developing new techniques for the prevention, diagnosis, treatment, and rehabilitation of neurological illnesses and injuries. The leadership of internationally respected physicians keeps Barrow at the forefront of neuroscience. The compassionate expertise of its extensive staff of nurses, technologists, therapists and support personnel is evident in every aspect of care provided.

Our mission is to advance the knowledge and practice of medicine in neuroscience through basic and clinical research, education of medical professionals, and innovation in clinical techniques and technology.

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Submissions from 2020

Spatial Mechanisms for Segregation of Competing Sounds, and a Breakdown in Spatial Hearing, John C. Middlebrooks and Michael F. Waters

Neurosurgical Management of Cancer Facial Pain, Zaman Mirzadeh, John P. Sheehy, Sharona Ben-Haim, and William S. Rosenberg

TLR4 (Toll-Like Receptor 4) Mediates the Development of Intracranial Aneurysm Rupture., Kazuha Mitsui, Taichi Ikedo, Yoshinobu Kamio, Hajime Furukawa, Michael T. Lawton, and Tomoki Hashimoto

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Involvement of Senescence and Mitochondrial Fission in Endothelial Cell Pro-Inflammatory Phenotype Induced by Angiotensin II, Masashi Miyao, Stephanie Cicalese, Tatsuo Kawai, Hannah A. Cooper, Michael J. Boyer, Katherine J. Elliott, Steven J. Forrester, Ryohei Kuroda, Victor Rizzo, Tomoki Hashimoto, Rosario Scalia, and Satoru Eguchi

TMEM100 is a key factor for specification of lymphatic endothelial progenitors, Eun Hye Moon, Yong Hwan Kim, Phuong Nhung Vu, Hyunjin Yoo, Kwonho Hong, Young Jae Lee, and S. Paul Oh

The Hitchhiker's Guide to Nucleocytoplasmic Trafficking in Neurodegeneration., Stephen Moore, Benjamin E Rabichow, and Rita Sattler

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Frontal cortex chitinase and pentraxin neuroinflammatory alterations during the progression of Alzheimer's disease., Marta Moreno-Rodriguez, Sylvia E Perez, Muhammad Nadeem, Michael Malek-Ahmadi, and Elliott J. Mufson

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Identifying the spatial and temporal dynamics of molecularly-distinct glioblastoma sub-populations, Bethan Morris, Lee Curtin, Andrea Hawkins-Daarud, Matthew E. Hubbard, Ruman Rahman, Stuart J. Smith, Dorothee Auer, Nhan L. Tran, Leland S. Hu, Jennifer M. Eschbacher, Kris A. Smith, Ashley Stokes, Kristin R. Swanson, and Markus R. Owen

Remote Ischemic Post-Conditioning Therapy is Protective in Mouse Model of Traumatic Optic Neuropathy, Muhammad Nadeem, Adam Kindelin, Laura Mahady, Kanchan Bhatia, Md Nasrul Hoda, Andrew F. Ducruet, and Saif Ahmad

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Targeting Molecular Mechanism of Vascular Smooth Muscle Senescence Induced by Angiotensin II, A Potential Therapy via Senolytics and Senomorphics, Keisuke Okuno, Stephanie Cicalese, Katherine J. Elliott, Tatsuo Kawai, Tomoki Hashimoto, and Satoru Eguchi

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Length-dependent MRI of hereditary neuropathy with liability to pressure palsies., Michael Pridmore, Ryan Castoro, Megan Simmons McCollum, Hakmook Kang, Jun Li, and Richard Dortch

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Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia., Mercedes Prudencio, Jack Humphrey, Sarah Pickles, Anna-Leigh Brown, Sarah E Hill, Jennifer M Kachergus, J Shi, Michael G Heckman, Matthew R Spiegel, Casey Cook, Yuping Song, Mei Yue, Lillian M Daughrity, Yari Carlomagno, Karen Jansen-West, Cristhoper Fernandez de Castro, Michael DeTure, Shunsuke Koga, Ying-Chih Wang, Prasanth Sivakumar, Cristian Bodo, Ana Candalija, Kevin Talbot, Bhuvaneish T Selvaraj, Karen Burr, Siddharthan Chandran, Jia Newcombe, Tammaryn Lashley, Isabel Hubbard, Demetra Catalano, Duyang Kim, Nadia Propp, Samantha Fennessey, Delphine Fagegaltier, Hemali Phatnani, Maria Secrier, Elizabeth Mc Fisher, Björn Oskarsson, Marka van Blitterswijk, Rosa Rademakers, Neil R Graff-Radford, Bradley F Boeve, David S Knopman, Ronald C Petersen, Keith A Josephs, E Aubrey Thompson, Towfique Raj, Michael Ward, Dennis W Dickson, Tania F Gendron, Pietro Fratta, Leonard Petrucelli, and Robert Bowser

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Preclinical testing of a novel niclosamide stearate prodrug therapeutic (NSPT) shows efficacy against osteosarcoma, Gireesh B. Reddy, David L. Kerr, Ivan Spasojevic, Artak Tovmasyan, David S. Hsu, Brian E. Brigman, Jason A. Somarelli, David Needham, and William C. Eward

Correcting Smad1/5/8, mTOR, and VEGFR2 treats pathology in hereditary hemorrhagic telangiectasia models., Santiago Ruiz, Haitian Zhao, Pallavi Chandakkar, Julien Papoin, Hyunwoo Choi, Aya Nomura-Kitabayashi, Radhika Patel, Matthew Gillen, Li Diao, Prodyot K Chatterjee, Mingzhu He, Yousef Al-Abed, Ping Wang, Christine N Metz, S Paul Oh, Lionel Blanc, Fabien Campagne, and Philippe Marambaud

Correcting Smad1/5/8, mTOR, and VEGFR2 treats pathology in hereditary hemorrhagic telangiectasia models, Santiago Ruiz, Haitian Zhao, Pallavi Chandakkar, Julien Papoin, Hyunwoo Choi, Aya Nomura-Kitabayashi, Radhika Patel, Matthew Gillen, Li Diao, Prodyot K. Chatterjee, Mingzhu He, Yousef Al-Abed, Ping Wang, Christine N. Metz, S. Paul Oh, Lionel Blanc, Fabien Campagne, and Philippe Marambaud

Identification of a pathogenic intronic KIF5A mutation in an ALS-FTD kindred, Sara Saez-Atienzar, Clifton L. Dalgard, Jinhui Ding, Adriano Chiò, Camile Alba, Dan N. Hupalo, Matthew D. Wilkerson, Robert Bowser, Erik P. Pioro, Richard Bedlack, and Bryan J. Traynor

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Global alterations to the choroid plexus blood-CSF barrier in amyotrophic lateral sclerosis, J. Saul, E. Hutchins, R Reiman, M Saul, L W. Ostrow, B T. Harris, K Van Keuren-Jensen, R Bowser, and N Bakkar

Variations among human lumbar spine segments and their relationships to in vitro biomechanics: A retrospective analysis of 281 motion segments from 85 cadaveric spines, Anna G.U. Sawa, Jennifer N. Lehrman, Neil R. Crawford, and Brian P. Kelly

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A practical method for multimodal registration and assessment of whole-brain disease burden using PET, MRI, and optical imaging, Matthew L. Scarpelli, Debbie R. Healey, Shwetal Mehta, Vikram D. Kodibagkar, and Christopher C. Quarles

Striatal Nurr1 Facilitates the Dyskinetic State and Exacerbates Levodopa-Induced Dyskinesia in a Rat Model of Parkinson's Disease, Rhyomi C. Sellnow, Kathy Steece-Collier, Feras Altwal, Ivette M. Sandoval, Jeffrey H. Kordower, Timothy J. Collier, Caryl E. Sortwell, Anthony R. West, and Fredric P. Manfredsson

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Further understanding the connection between Alzheimer's disease and Down syndrome, Heather M. Snyder, Lisa J. Bain, Adam M. Brickman, Maria C. Carrillo, Anna J. Esbensen, Joaquin M. Espinosa, Fabian Fernandez, Juan Fortea, Sigan L. Hartley, Elizabeth Head, James Hendrix, Priya S. Kishnani, Florence Lai, Patrick Lao, Cynthia Lemere, William Mobley, Elliott J. Mufson, Huntington Potter, Shahid H. Zaman, Ann Charlotte Granholm, H. Diana Rosas, Andre Strydom, Michelle Sie Whitten, and Michael S. Rafii

Striatal Nurr1, but not FosB expression links a levodopa-induced dyskinesia phenotype to genotype in Fisher 344 vs. Lewis hemiparkinsonian rats, Kathy Steece-Collier, Timothy J. Collier, Jack W. Lipton, Jennifer A. Stancati, Mary E. Winn, Allyson Cole-Strauss, Rhyomi Sellnow, Melissa M. Conti, Natosha M. Mercado, Eduardo A. Nillni, Caryl E. Sortwell, Fredric P. Manfredsson, and Christopher Bishop

Systematic assessment of multi-echo dynamic susceptibility contrast MRI using a digital reference object., A. Stokes, Natenael B Semmineh, Ashley Nespodzany, Laura C Bell, and C. Quarles

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YAP-dependent necrosis occurs in early stages of Alzheimer's disease and regulates mouse model pathology., Hikari Tanaka, Hidenori Homma, Kyota Fujita, Kanoh Kondo, Shingo Yamada, Xiaocen Jin, Masaaki Waragai, Gaku Ohtomo, Atsushi Iwata, Kazuhiko Tagawa, Naoki Atsuta, Masahisa Katsuno, Naoki Tomita, Katsutoshi Furukawa, Yuko Saito, Takashi Saito, Ayaka Ichise, Shinsuke Shibata, Hiroyuki Arai, Takaomi Saido, Marius Sudol, Shin-Ichi Muramatsu, Hideyuki Okano, Elliott J. Mufson, Gen Sobue, Shigeo Murayama, and Hitoshi Okazawa

Antibacterial Activity of Synthetic Cationic Iron Porphyrins, Artak Tovmasyan, Ines Batinic-Haberle, and Ludmil Benov

Neutrophil extracellular traps exacerbate neurological deficits after traumatic brain injury, Kumar Vaibhav, Molly Braun, Katelyn Alverson, Hesam Khodadadi, Ammar Kutiyanawalla, Ayobami Ward, Christopher Banerjee, Tyler Sparks, Aneeq Malik, Mohammad H. Rashid, Mohammad Badruzzaman Khan, Michael F. Waters, David C. Hess, Ali S. Arbab, John R. Vender, Nasrul Hoda, Babak Baban, and Krishnan M. Dhandapani

Robotic Spine Surgery: Current State in Minimally Invasive Surgery, Chau D. Vo, Bowen Jiang, Tej D. Azad, Neil R. Crawford, Ali Bydon, and Nicholas Theodore

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Cross-sectional and longitudinal measures of chitinase proteins in amyotrophic lateral sclerosis and expression of CHI3L1 in activated astrocytes., Lucas Vu, Jiyan An, Tina Kovalik, Tania Gendron, Leonard Petrucelli, and Robert Bowser

Surgical Approaches to Stroke Risk Reduction, Michael F. Waters

Optimizing Next-Generation Care Systems for Stroke, D Andrew Wilkinson, Ashutosh P. Jadhav, and Andrew F. Ducruet

Patterns and disparities in human papillomavirus (HPV) vaccine uptake for young female adolescents among U.S. States: NIS-teen (2008–2016), Wonsuk Yoo, Alexis Koskan, Matthew Scotch, Heidi Pottinger, Warner K. Huh, and Deborah Helitzer

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CRISPR-mediated gene correction links the ATP7A M1311V mutations with amyotrophic lateral sclerosis pathogenesis in one individual., Yeomin Yun, Sung-Ah Hong, Ka-Kyung Kim, Daye Baek, Dongsu Lee, Ashwini M Londhe, Minhyung Lee, Jihyeon Yu, Zachary T McEachin, Gary J Bassell, Robert Bowser, Chadwick M Hales, Sung-Rae Cho, Janghwan Kim, Ae Nim Pae, Eunji Cheong, Sangwoo Kim, Nicholas M Boulis, Sangsu Bae, and Yoon Ha

Submissions from 2019

Neuropathological Correlates Of Amyloid Pet Imaging In Down Syndrome, Eric E. Abrahamson, Elizabeth Head, Ira T. Lott, Benjamin L. Handen, Elliott J. Mufson, Bradley T. Christian, William E. Klunk, and Milos D. Ikonomovic

Connectivity and Centrality Characteristics of the Epileptogenic Focus Using Directed Network Analysis, Joshua A. Adkinson, Bharat Karumuri, Timothy N. Hutson, Rui Liu, Omar Alamoudi, Ioannis Vlachos, and Leonidas Iasemidis

The Role of Complement C3a Receptor in Stroke, Saif Ahmad, Kanchan Bhatia, Adam Kindelin, and Andrew F. Ducruet

Acetyl-11-keto-β-boswellic acid (AKBA) Attenuates Oxidative Stress, Inflammation, Complement Activation and Cell Death in Brain Endothelial Cells Following OGD/Reperfusion, Saif Ahmad, Shah Alam Khan, Adam Kindelin, Tasha Mohseni, Kanchan Bhatia, Md Nasrul Hoda, and Andrew F. Ducruet

C3a receptor inhibition protects brain endothelial cells against oxygen-glucose deprivation/reperfusion, Saif Ahmad, Adam Kindelin, Shah Alam Khan, Maaz Ahmed, Md Nasrul Hoda, Kanchan Bhatia, and Andrew F. Ducruet

First spine surgery utilizing real-time image-guided robotic assistance, A. Karim Ahmed, Corinna C. Zygourakis, Samuel Kalb, Alex M. Zhu, Camilo A. Molina, Bowen Jiang, Ari M. Blitz, Ali Bydon, Neil R. Crawford, and Nicholas Theodore

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Approaches to Multimodality Monitoring in Pediatric Traumatic Brain Injury, Brian Appavu, Brian T. Burrows, Stephen Foldes, and P David Adelson

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Clinical trials for pediatric traumatic brain injury: definition of insanity?, Brian Appavu, Stephen T. Foldes, and P David Adelson

Shared polygenic risk and causal inferences in amyotrophic lateral sclerosis, Sara Bandres-Ciga, Alastair J. Noyce, Gibran Hemani, Aude Nicolas, Andrea Calvo, Gabriele Mora, Alessandro Arosio, Marco Barberis, Ilaria Bartolomei, Stefania Battistini, Michele Benigni, Giuseppe Borghero, Maura Brunetti, Stefania Cammarosano, Antonino Cannas, Antonio Canosa, Margherita Capasso, Claudia Caponnetto, Carla Caredda, Paola Carrera, Federico Casale, Sebastiano Cavallaro, Adriano Chiò, Tiziana Colletti, Francesca L. Conforti, Amelia Conte, Lucia Corrado, Emanuela Costantino, Sandra D'Alfonso, Antonio Fasano, and Cinzia Femiano

Flow-Diverter Stent With an Incorporated Flow Sensor-The Integration of a Treatment and Diagnostic Device for Intracranial Aneurysms, Jacob F. Baranoski and Andrew F. Ducruet

Nanoparticle-Facilitated Delivery of Antioxidant Therapy following Aneurysmal Subarachnoid Hemorrhage, Jacob F. Baranoski and Andrew F. Ducruet

Recent Advances in Basic Research for Brain Arteriovenous Malformation, Leandro Barbosa Do Prado, Chul Han, S. Paul Oh, and Hua Su

Evaluating Multisite Rcbv Consistency From Dsc-Mri Imaging Protocols And Postprocessing Software Across The Nci Quantitative Imaging Network Sites Using A Digital Reference Object (Dro), Laura C. Bell, Natenael Semmineh, Hongyu An, Cihat Eldeniz, Richard Wahl, Kathleen M. Schmainda, Melissa A. Prah, Bradley J. Erickson, Panagiotis Korfiatis, Chengyue Wu, Anna G. Sorace, Thomas E. Yankeelov, Neal Rutledge, Thomas L. Chenevert, Dariya Malyarenko, Yichu Liu, Andrew Brenner, Lel S. Hu, Yuxiang Zhou, Jerrold L. Boxerman, Yi Fen Yen, Jayashree Kalpathy-Cramer, Andrew L. Beers, Mark Muzi, Ananth J. Madhuranthakam, Marco Pinho, Brian Johnson, and C. Chad Quarles

Analysis Of Postprocessing Steps For Residue Function Dependent Dynamic Susceptibility Contrast (Dsc)-Mri Biomarkers And Their Clinical Impact On Glioma Grading For Both 1.5 And 3T, Laura C. Bell, Ashley M. Stokes, and C. Chad Quarles

Neurofilaments in pre-symptomatic ALS and the impact of genotype., Michael Benatar, Joanne Wuu, Vittoria Lombardi, Andreas Jeromin, Robert Bowser, Peter M Andersen, and Andrea Malaspina

Basic Concepts in Viral Vector-Mediated Gene Therapy, Matthew J. Benskey, Ivette M. Sandoval, Kathryn Miller, Rhyomi L. Sellnow, Aysegul Gezer, Nathan C. Kuhn, Roslyn Vashon, and Fredric P. Manfredsson

Revisiting How the Brain Senses Glucose-And Why, Marie Aare Bentsen, Zaman Mirzadeh, and Michael W. Schwartz

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Resting-state fMRI in disorders of consciousness to facilitate early therapeutic intervention, Varina L. Boerwinkle, Salvatore J. Torrisi, Stephen T. Foldes, Iris Marku, Manish Ranjan, Angus A. Wilfong, and P David Adelson

Biomechanical Testing of a 3D-printed L5 Vertebral Body Model, Michael A. Bohl, Clinton D. Morgan, Michael A. Mooney, Garrett J. Repp, Jennifer N. Lehrman, Brian P. Kelly, Steve W. Chang, Jay D. Turner, and U Kumar Kakarla

ALSUntangled 48: Perampanel (Fycompa)., Robert Bowser

ALSUntangled No. 47: RT001., Robert Bowser

ALSUntangled 46: penicillin G/hydrocortisone., Robert Bowser and ALSUntangled Group

ALSUntangled no. 49: resveratrol., Robert Bowser and ALSUntangled Group

ALSUntangled No. 50: Antifungal Therapy., Robert Bowser and ALSUntangled Group

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Not only cancer: the long non-coding RNA MALAT1 affects the repertoire of alternatively spliced transcripts and circular RNAs in multiple sclerosis, Giulia Cardamone, Elvezia M. Paraboschi, Giulia Soldà, Claudia Cantoni, Domenico Supino, Laura Piccio, Stefano Duga, and Rosanna Asselta

Iatrogenic pseudoaneurysm rupture of the anterior cerebral artery after placement of an external ventricular drain, treated with clip-wrapping: a case report and review of the literature, Joshua S. Catapano, Michaela Lee, Damjan Veljanoski, Alexander C. Whiting, Scott Brigeman, Clinton D. Morgan, Mohamed A. Labib, Andrew F. Ducruet, and Peter Nakaji

Highlights of the 13th International Hereditary Hemorrhagic Telangiectasia Scientific conference, Hyunwoo Choi, Miles B. Conrad, S. Paul Oh, Beth L. Roman, and Andrew J. White

The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk, Yuetiva Deming, Fabia Filipello, Francesca Cignarella, Claudia Cantoni, Simon Hsu, Robert Mikesell, Zeran Li, Jorge L Del-Aguila, Umber Dube, Fabiana Geraldo Farias, Joseph Bradley, John Budde, Laura Ibanez, Maria Victoria Fernandez, Kaj Blennow, Henrik Zetterberg, Amanda Heslegrave, Per M Johansson, Johan Svensson, Bengt Nellgård, Alberto Lleo, Daniel Alcolea, Jordi Clarimon, Lorena Rami, José Luis Molinuevo, Marc Suárez-Calvet, Estrella Morenas-Rodríguez, Gernot Kleinberger, Michael Ewers, Oscar Harari, Christian Haass, Thomas J Brett, Bruno A Benitez, Celeste M Karch, Laura Piccio, and Carlos Cruchaga

Mutations in Chromatin Modifier and Ephrin Signaling Genes in Vein of Galen Malformation, Daniel Duran, Xue Zeng, Sheng Chih Jin, Jungmin Choi, Carol Nelson-Williams, Bogdan Yatsula, Jonathan Gaillard, Charuta Gavankar Furey, Qiongshi Lu, Andrew T. Timberlake, Weilai Dong, Michelle A. Sorscher, Erin Loring, Jennifer Klein, August Allocco, Ava Hunt, Sierra Conine, Jason K. Karimy, Mark W. Youngblood, Jinwei Zhang, Michael L. DiLuna, Charles C. Matouk, Shrikant Mane, Irina R. Tikhonova, Christopher Castaldi, Francesc López-Giráldez, James Knight, Shozeb Haider, Mariya Soban, Seth L. Alper, Masaki Komiyama, and Andrew F. Ducruet

Organized Social Activity, Physical Exercise, and the Risk of Insomnia Symptoms Among Community-Dwelling Older Adults, Yohannes W. Endeshaw and Wonsuk Yoo

Pazopanib may reduce bleeding in hereditary hemorrhagic telangiectasia, Marie E. Faughnan, James R. Gossage, Murali M. Chakinala, S. Paul Oh, Raj Kasthuri, Christopher C.W. Hughes, Justin P. McWilliams, Joseph G. Parambil, Nicholas Vozoris, Jill Donaldson, Gitanjali Paul, Pamela Berry, and Dennis L. Sprecher

Alpha6-Containing Nicotinic Acetylcholine Receptor Is A Highly Sensitive Target Of Alcohol, Fenfei Gao, Dejie Chen, Xiaokuang Ma, Sterling Sudweeks, Jordan T. Yorgason, Ming Gao, Dharshaun Turner, Jason Brek Eaton, J. Michael McIntosh, Ronald J. Lukas, Paul Whiteaker, Yongchang Chang, Scott C. Steffensen, and Jie Wu

Brain-Derived Neurotrophic Factor (Bdnf) And Trkb Hippocampal Gene Expression Are Putative Predictors Of Neuritic Plaque And Neurofibrillary Tangle Pathology, Stephen D. Ginsberg, Michael H. Malek-Ahmadi, Melissa J. Alldred, Yinghua Chen, Kewei Chen, Moses V. Chao, Scott E. Counts, and Elliott J. Mufson

Selective Decline Of Neurotrophin And Neurotrophin Receptor Genes Within Ca1 Pyramidal Neurons And Hippocampus Proper: Correlation With Cognitive Performance And Neuropathology In Mild Cognitive Impairment And Alzheimer'S Disease, Stephen D. Ginsberg, Michael H. Malek-Ahmadi, Melissa J. Alldred, Shaoli Che, Irina Elarova, Yinghua Chen, Freddy Jeanneteau, Thorsten M. Kranz, Moses V. Chao, Scott E. Counts, and Elliott J. Mufson

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Heterogeneous nuclear ribonucleoproteins R and Q accumulate in pathological inclusions in FTLD-FUS, Lauren M. Gittings, Sandrine C. Foti, Bridget C. Benson, Priya Gami-Patel, Adrian M. Isaacs, and Tammaryn Lashley

Biomechanical Evaluation Of Cervicothoracic Junction Fusion Constructs, Jakub Godzik, Jonathan F. Dalton, Eduardo Martinez-del-Campo, Anna G.U.S. Newcomb, Felix Dominguez, Phillip M. Reyes, Nicholas Theodore, Brian P. Kelly, and Neil R. Crawford

Supplemental Rods Are Needed To Maximally Reduce Rod Strain Across The Lumbosacral Junction With Tlif But Not Alif In Long Constructs, Jakub Godzik, Randall J. Hlubek, Anna G.U.S. Newcomb, Jennifer N. Lehrman, Bernardo de Andrada, S. Harrison Farber, Lawrence G. Lenke, Brian P. Kelly, and Jay D. Turner

Impact Of Connector Placement And Design On Bending Stiffness Of Spinal Constructs, Jakub Godzik, Nick Hool, Jonathan F. Dalton, Alexander C. Whiting, Anna G.U.S. Newcomb, Brian P. Kelly, and Neil R. Crawford

Tailoring selection of transforaminal interbody spacers based on biomechanical characteristics and surgical goals: evaluation of an expandable spacer., Jakub Godzik, Jennifer N Lehrman, Anna G U S Newcomb, Ram Kumar Menon, Alexander C Whiting, Brian P. Kelly, and Laura A Snyder

A clinical comparison of Atlas and LVIS Jr stent-assisted aneurysm coiling, Bradley A. Gross, William J. Ares, Andrew F. Ducruet, Ashutosh P. Jadhav, Tudor G. Jovin, and Brian Thomas Jankowitz

Exosome Release And Cargo In Down Syndrome, Eric D. Hamlett, Angela LaRosa, Elliott J. Mufson, Juan Fortea, Aurélie Ledreux, and Ann Charlotte Granholm

Iliac Screws May Not Be Necessary In Long-Segment Constructs With L5€“S1 Anterior Lumbar Interbody Fusion: Cadaveric Study Of Stability And Instrumentation Strain, Randall J. Hlubek, Jakub Godzik, Anna G.U.S. Newcomb, Jennifer N. Lehrman, Bernardo de Andrada, Michael A. Bohl, Samuel H. Farber, Brian P. Kelly, and Jay D. Turner

Translating Preclinical Mri Methods To Clinical Oncology, David A. Hormuth, Anna G. Sorace, John Virostko, Richard G. Abramson, Zaver M. Bhujwalla, Pedro Enriquez-Navas, Robert Gillies, John D. Hazle, Ralph P. Mason, C. Chad Quarles, Jared A. Weis, Jennifer G. Whisenant, Junzhong Xu, and Thomas E. Yankeelov

Accurate Patient-Specific Machine Learning Models Of Glioblastoma Invasion Using Transfer Learning, L. S. Hu, H. Yoon, J. M. Eschbacher, L. C. Baxter, A. C. Dueck, A. Nespodzany, K. A. Smith, P. Nakaji, Y. Xu, L. Wang, J. P. Karis, A. J. Hawkins-Daarud, K. W. Singleton, P. R. Jackson, B. J. Anderies, B. R. Bendok, R. S. Zimmerman, C. Quarles, A. B. Porter-Umphrey, M. M. Mrugala, A. Sharma, J. M. Hoxworth, M. G. Sattur, N. Sanai, P. E. Koulemberis, C. Krishna, J. R. Mitchell, T. Wu, N. L. Tran, K. R. Swanson, and J. Li

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Dietary Intake Regulates the Circulating Inflammatory Monocyte Pool, Stefan Jordan, Navpreet Tung, Maria Casanova-Acebes, Christie Chang, Claudia Cantoni, Dachuan Zhang, Theresa H. Wirtz, Shruti Naik, Samuel A. Rose, Chad N. Brocker, Anastasiia Gainullina, Daniel Hornburg, Sam Horng, Barbara B. Maier, Paolo Cravedi, Derek LeRoith, Frank J. Gonzalez, Felix Meissner, Jordi Ochando, Adeeb Rahman, Jerry E. Chipuk, Maxim N. Artyomov, Paul S. Frenette, Laura Piccio, Marie-Luise Berres, Emily J. Gallagher, and Miriam Merad

GFR-α1 Expression in Substantia Nigra Increases Bilaterally Following Unilateral Striatal GDNF in Aged Rats and Attenuates Nigral Tyrosine Hydroxylase Loss Following 6-OHDA Nigrostriatal Lesion, Ella A. Kasanga, Catherine L. Owens, Mark A. Cantu, Adam D. Richard, Richard W. Davis, Lisa M. McDivitt, Blake Blancher, Brandon S. Pruett, Christopher Tan, Austin Gajewski, Fredric P. Manfredsson, Vicki A. Nejtek, and Michael F. Salvatore

Maternal Choline Supplementation Alters Basal Forebrain Cholinergic Neuron Gene Expression In The Ts65Dn Mouse Model Of Down Syndrome, Christy M. Kelley, Stephen D. Ginsberg, Melissa J. Alldred, Barbara J. Strupp, and Elliott J. Mufson

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Tau pathology in the medial temporal lobe of athletes with chronic traumatic encephalopathy: A chronic effects of neurotrauma consortium study, Christy M. Kelley, Sylvia E. Perez, and Elliott J. Mufson

Enhancing Natural Killer Cells Is Beneficial In Multiple Sclerosis €“ No, Qiang Liu and Fu Dong Shi

ACR Appropriateness Criteria Acute Mental Status Change, Delirium, and New Onset Psychosis, Michael D. Luttrull, Daniel J. Boulter, Claudia F. Kirsch, Joseph M. Aulino, Joshua S. Broder, Santanu Chakraborty, Asim F. Choudhri, Andrew F. Ducruet, A Tuba Kendi, Ryan K. Lee, David S. Liebeskind, William Mack, Toshio Moritani, Robert P. Roca, Lubdha M. Shah, Aseem Sharma, Robert Y. Shih, Sophia C. Symko, and Julie Bykowski

Hdac2 Dysregulation In The Nucleus Basalis Of Meynert During The Progression Of Alzheimer'S Disease, L. Mahady, M. Nadeem, M. Malek-Ahmadi, K. Chen, S. E. Perez, and E. J. Mufson

Stapled EGFR peptide reduces inflammatory breast cancer and inhibits additional HER-driven models of cancer, Sabrina A. Maisel, Derrick Broka, Benjamin Atwell, Thomas Bunch, Robert Kupp, Shiv K. Singh, Shwetal Mehta, and Joyce Schroeder

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Trafficking of immune cells across the blood-brain barrier is modulated by neurofibrillary pathology in tauopathies, Petra Majerova, Alena Michalicova, Martin Cente, Jozef Hanes, Jozef Vegh, Agnes Kittel, Nina Kosikova, Viera Cigankova, Sandra Mihaljevic, Santosh Jadhav, and Andrej Kovac

Cerebral Amyloid Angiopathy And Neuritic Plaque Pathology Correlate With Cognitive Decline In Elderly Non-Demented Individuals, Michael Malek-Ahmadi, Kewei Chen, Sylvia E. Perez, and Elliott J. Mufson

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Glycolysis Upregulation Is Neuroprotective As A Compensatory Mechanism In Als, Ernesto Manzo, Ileana Lorenzini, Dianne Barrameda, Abigail G. O'Conner, Jordan M. Barrows, Alexander Starr, Tina Kovalik, Benjamin E. Rabichow, Erik M. Lehmkuhl, Dakotah D. Shreiner, Archi Joardar, Jean Charles Liévens, Robert Bowser, Rita Sattler, and Daniela C. Zarnescu

Disruption Of Met Receptor Tyrosine Kinase An Autism Risk Factor Impairs Developmental Synaptic Plasticity In The Hippocampus, Xiaokuang Ma, Ke Chen, Zhongming Lu, Mariel Piechowicz, Qiang Liu, Jie Wu, and Shenfeng Qiu

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Mechanisms Of Cannabinoid Cb 2 Receptor-Mediated Reduction Of Dopamine Neuronal Excitability In Mouse Ventral Tegmental Area, Zegang Ma, Fenfei Gao, Brett Larsen, Ming Gao, Zhihua Luo, Dejie Chen, Xiaokuang Ma, Shenfeng Qiu, Yu Zhou, Junxia Xie, Zheng Xiong Xi, and Jie Wu

Cocaine Potently Blocks Neuronal α3β4 Nicotinic Acetylcholine Receptors In Sh-Sy5Y Cells, Ze gang Ma, Nan Jiang, Yuan bing Huang, Xiao kuang Ma, Jason Brek Eaton, Ming Gao, Yong Chang, Ronald J. Lukas, Paul Whiteaker, Janet Neisewander, and Jie Wu

Lipid And Polymer Blended Polyester Nanoparticles Loaded With Adapalene For Activation Of Retinoid Signaling In The Cns Following Intravenous Administration, David X. Medina, Eugene P. Chung, Robert Bowser, and Rachael W. Sirianni

Molecularly defined cortical astroglia subpopulation modulates neurons via secretion of Norrin, Sean J. Miller, Thomas Philips, Namho Kim, Raha Dastgheyb, Zhuoxun Chen, Yi-Chun Hsieh, J Gavin Daigle, Malika Datta, Jeannie Chew, Svetlana Vidensky, Jacqueline T. Pham, Ethan G. Hughes, Michael B. Robinson, Rita Sattler, Raju Tomer, Jung Soo Suk, Dwight E. Bergles, Norman Haughey, Mikhail Pletnikov, Justin Hanes, and Jeffrey D. Rothstein

Perineuronal Net Formation during the Critical Period for Neuronal Maturation in the Hypothalamic Arcuate Nucleus, Zaman Mirzadeh, Kimberly M. Alonge, Elaine Cabrales, Vicente Herranz-Pérez, Jarrad M. Scarlett, Jenny M. Brown, Rim Hassouna, Miles E. Matsen, Hong T. Nguyen, Jose Manuel Garcia-Verdugo, Lori M. Zeltser, and Michael W. Schwartz

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C9orf72 arginine-rich dipeptide proteins interact with ribosomal proteins in vivo to induce a toxic translational arrest that is rescued by eIF1A, Thomas G. Moens, Teresa Niccoli, Katherine M. Wilson, Magda L. Atilano, Nicol Birsa, Lauren M. Gittings, Benedikt V. Holbling, Miranda C. Dyson, Annora Thoeng, Jacob Neeves, Idoia Glaria, Lu Yu, Julia Bussmann, Erik Storkebaum, Mercedes Pardo, Jyoti S. Choudhary, Pietro Fratta, Linda Partridge, and Adrian M. Isaacs

Adar2 Mislocalization And Widespread Rna Editing Aberrations In C9Orf72-Mediated Als/Ftd, Stephen Moore, Eric Alsop, Ileana Lorenzini, Alexander Starr, Benjamin E. Rabichow, Emily Mendez, Jennifer L. Levy, Camelia Burciu, Rebecca Reiman, Jeannie Chew, Veronique V. Belzil, Dennis W. Dickson, Janice Robertson, Kim A. Staats, Justin K. Ichida, Leonard Petrucelli, Kendall Van Keuren-Jensen, and Rita Sattler

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Nerve Growth Factor Pathobiology During The Progression Of Alzheimer's Disease, Elliott J. Mufson, Scott E. Counts, Stephen D. Ginsberg, Laura Mahady, Sylvia E. Perez, Stephen M. Massa, Frank M. Longo, and Milos D. Ikonomovic

Astrocytic Changes With Aging And Alzheimer'S Disease-Type Pathology In Chimpanzees, Emily L. Munger, Melissa K. Edler, William D. Hopkins, John J. Ely, Joseph M. Erwin, Daniel P. Perl, Elliott J. Mufson, Patrick R. Hof, Chet C. Sherwood, and Mary Ann Raghanti

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Profiling the mouse brain endothelial transcriptome in health and disease models reveals a core blood-brain barrier dysfunction module, Roeben Nocon Munji, Allison Luen Soung, Geoffrey Aaron Weiner, Fabien Sohet, Bridgette Deanne Semple, Alpa Trivedi, Kayleen Gimlin, Masakazu Kotoda, Masaaki Korai, Sidar Aydin, Austin Batugal, Anne Christelle Cabangcala, Patrick Georg Schupp, Michael Clark Oldham, Tomoki Hashimoto, Linda J. Noble-Haeusslein, and Richard Daneman

GSTA4 mediates reduction of cisplatin ototoxicity in female mice., Hyo-Jin Park, Mi-Jung Kim, Christina Rothenberger, Ashok Kumar, Edith M Sampson, Dalian Ding, Chul Han, Karessa White, Kevin Boyd, Senthilvelan Manohar, Yong-Hwan Kim, Maria S Ticsa, Aaron S Gomez, Isabela Caicedo, Upal Bose, Paul J Linser, Takuya Miyakawa, Masaru Tanokura, Thomas C Foster, Richard Salvi, and Shinichi Someya

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Probing glioblastoma and its microenvironment using single-nucleus and single-cell sequencing, Sen Peng, Seungchan Kim, Harshil Dhruv, Sanhita Rath, Connor Vuong, Saumya Bollam, Jenny Eschbacher, Xishuang Dong, Shwetal Mehta, Nader Sanai, and Michael Berens