Intravenously Administered, Retinoid Activating Nanoparticles Increase Lifespan and Reduce Neurodegeneration in the SOD1

Authors

David X. Medina, Barrow Neurological InstituteFollow
Eugene P Chung
Collin D Teague
Robert Bowser, Barrow Neurological InstituteFollow
Rachael W Sirianni

Department

Neurobiology

Document Type

Article

Abstract

Dysregulation of the retinoic acid (RA) signaling pathway is observed in amyotrophic lateral sclerosis (ALS) and other neurodegenerative disorders. Here, we investigated the therapeutic potential of retinoid activation via the RA receptor β (RARβ) in the SOD1

Publication Date

1-1-2020

Publication Title

Front Bioeng Biotechnol

ISSN

2296-4185

Volume

8

First Page

224

Last Page

224

PubMed ID

32292776

Digital Object Identifier (DOI)

10.3389/fbioe.2020.00224

Recommended Citation

Medina, David X.; Chung, Eugene P; Teague, Collin D; Bowser, Robert; and Sirianni, Rachael W, "Intravenously Administered, Retinoid Activating Nanoparticles Increase Lifespan and Reduce Neurodegeneration in the SOD1" (2020). Translational Neuroscience. 473.
https://scholar.barrowneuro.org/neurobiology/473