The Barrow Neurological Institute is proud of its reputation as a medical research facility and is home to some of the most sophisticated research programs outside of an academic setting in the Southwestern United States. Researchers in the Barrow Neurosurgery Research Center are devoted to learning more about the causes of and treatments for a wide range of disorders, such as stroke, aneurysms, spinal cord injury, and hydrocephalus. Our research has led to treatments that are being used around the world. Within the Department are neurosurgeons who subspecialize in cerebrovascular and skull base, functional and stereotactic, pediatric, spine, tumor, and endovascular neurosurgery.

Physicians, scientists, and expert clinical staff come together with a commitment to developing new techniques for the prevention, diagnosis, treatment, and rehabilitation of neurological illnesses and injuries. The leadership of internationally respected physicians keeps Barrow at the forefront of neuroscience. The compassionate expertise of its extensive staff of nurses, technologists, therapists and support personnel is evident in every aspect of care provided.

Our mission is to advance the knowledge and practice of medicine in neuroscience through basic and clinical research, education of medical professionals, and innovation in clinical techniques and technology.

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Submissions from 2019

Accurate Patient-Specific Machine Learning Models Of Glioblastoma Invasion Using Transfer Learning, L. S. Hu, H. Yoon, J. M. Eschbacher, L. C. Baxter, A. C. Dueck, A. Nespodzany, K. A. Smith, P. Nakaji, Y. Xu, L. Wang, J. P. Karis, A. J. Hawkins-Daarud, K. W. Singleton, P. R. Jackson, B. J. Anderies, B. R. Bendok, R. S. Zimmerman, C. Quarles, A. B. Porter-Umphrey, M. M. Mrugala, A. Sharma, J. M. Hoxworth, M. G. Sattur, N. Sanai, P. E. Koulemberis, C. Krishna, J. R. Mitchell, T. Wu, N. L. Tran, K. R. Swanson, and J. Li

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Dietary Intake Regulates the Circulating Inflammatory Monocyte Pool, Stefan Jordan, Navpreet Tung, Maria Casanova-Acebes, Christie Chang, Claudia Cantoni, Dachuan Zhang, Theresa H. Wirtz, Shruti Naik, Samuel A. Rose, Chad N. Brocker, Anastasiia Gainullina, Daniel Hornburg, Sam Horng, Barbara B. Maier, Paolo Cravedi, Derek LeRoith, Frank J. Gonzalez, Felix Meissner, Jordi Ochando, Adeeb Rahman, Jerry E. Chipuk, Maxim N. Artyomov, Paul S. Frenette, Laura Piccio, Marie-Luise Berres, Emily J. Gallagher, and Miriam Merad

GFR-α1 Expression in Substantia Nigra Increases Bilaterally Following Unilateral Striatal GDNF in Aged Rats and Attenuates Nigral Tyrosine Hydroxylase Loss Following 6-OHDA Nigrostriatal Lesion, Ella A. Kasanga, Catherine L. Owens, Mark A. Cantu, Adam D. Richard, Richard W. Davis, Lisa M. McDivitt, Blake Blancher, Brandon S. Pruett, Christopher Tan, Austin Gajewski, Fredric P. Manfredsson, Vicki A. Nejtek, and Michael F. Salvatore

Maternal Choline Supplementation Alters Basal Forebrain Cholinergic Neuron Gene Expression In The Ts65Dn Mouse Model Of Down Syndrome, Christy M. Kelley, Stephen D. Ginsberg, Melissa J. Alldred, Barbara J. Strupp, and Elliott J. Mufson

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Tau pathology in the medial temporal lobe of athletes with chronic traumatic encephalopathy: A chronic effects of neurotrauma consortium study, Christy M. Kelley, Sylvia E. Perez, and Elliott J. Mufson

Enhancing Natural Killer Cells Is Beneficial In Multiple Sclerosis €“ No, Qiang Liu and Fu Dong Shi

ACR Appropriateness Criteria Acute Mental Status Change, Delirium, and New Onset Psychosis, Michael D. Luttrull, Daniel J. Boulter, Claudia F. Kirsch, Joseph M. Aulino, Joshua S. Broder, Santanu Chakraborty, Asim F. Choudhri, Andrew F. Ducruet, A Tuba Kendi, Ryan K. Lee, David S. Liebeskind, William Mack, Toshio Moritani, Robert P. Roca, Lubdha M. Shah, Aseem Sharma, Robert Y. Shih, Sophia C. Symko, and Julie Bykowski

An Epidermoid Cyst of the Thoracic Spine in an Elderly Patient., Takuma Maeda, Kazuhiko Mishima, Jungo Imanishi, Mitsuaki Shirahata, Tomonari Suzuki, Jun-Ichi Adachi, Atsushi Sasaki, and Ryo Nishikawa

Hdac2 Dysregulation In The Nucleus Basalis Of Meynert During The Progression Of Alzheimer'S Disease, L. Mahady, M. Nadeem, M. Malek-Ahmadi, K. Chen, S. E. Perez, and E. J. Mufson

Stapled EGFR peptide reduces inflammatory breast cancer and inhibits additional HER-driven models of cancer, Sabrina A. Maisel, Derrick Broka, Benjamin Atwell, Thomas Bunch, Robert Kupp, Shiv K. Singh, Shwetal Mehta, and Joyce Schroeder

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Trafficking of immune cells across the blood-brain barrier is modulated by neurofibrillary pathology in tauopathies, Petra Majerova, Alena Michalicova, Martin Cente, Jozef Hanes, Jozef Vegh, Agnes Kittel, Nina Kosikova, Viera Cigankova, Sandra Mihaljevic, Santosh Jadhav, and Andrej Kovac

Cerebral Amyloid Angiopathy And Neuritic Plaque Pathology Correlate With Cognitive Decline In Elderly Non-Demented Individuals, Michael Malek-Ahmadi, Kewei Chen, Sylvia E. Perez, and Elliott J. Mufson

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Glycolysis Upregulation Is Neuroprotective As A Compensatory Mechanism In Als, Ernesto Manzo, Ileana Lorenzini, Dianne Barrameda, Abigail G. O'Conner, Jordan M. Barrows, Alexander Starr, Tina Kovalik, Benjamin E. Rabichow, Erik M. Lehmkuhl, Dakotah D. Shreiner, Archi Joardar, Jean Charles Liévens, Robert Bowser, Rita Sattler, and Daniela C. Zarnescu

Disruption Of Met Receptor Tyrosine Kinase An Autism Risk Factor Impairs Developmental Synaptic Plasticity In The Hippocampus, Xiaokuang Ma, Ke Chen, Zhongming Lu, Mariel Piechowicz, Qiang Liu, Jie Wu, and Shenfeng Qiu

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Mechanisms Of Cannabinoid Cb 2 Receptor-Mediated Reduction Of Dopamine Neuronal Excitability In Mouse Ventral Tegmental Area, Zegang Ma, Fenfei Gao, Brett Larsen, Ming Gao, Zhihua Luo, Dejie Chen, Xiaokuang Ma, Shenfeng Qiu, Yu Zhou, Junxia Xie, Zheng Xiong Xi, and Jie Wu

Cocaine Potently Blocks Neuronal α3β4 Nicotinic Acetylcholine Receptors In Sh-Sy5Y Cells, Ze gang Ma, Nan Jiang, Yuan bing Huang, Xiao kuang Ma, Jason Brek Eaton, Ming Gao, Yong Chang, Ronald J. Lukas, Paul Whiteaker, Janet Neisewander, and Jie Wu

Lipid And Polymer Blended Polyester Nanoparticles Loaded With Adapalene For Activation Of Retinoid Signaling In The Cns Following Intravenous Administration, David X. Medina, Eugene P. Chung, Robert Bowser, and Rachael W. Sirianni

Molecularly defined cortical astroglia subpopulation modulates neurons via secretion of Norrin, Sean J. Miller, Thomas Philips, Namho Kim, Raha Dastgheyb, Zhuoxun Chen, Yi-Chun Hsieh, J Gavin Daigle, Malika Datta, Jeannie Chew, Svetlana Vidensky, Jacqueline T. Pham, Ethan G. Hughes, Michael B. Robinson, Rita Sattler, Raju Tomer, Jung Soo Suk, Dwight E. Bergles, Norman Haughey, Mikhail Pletnikov, Justin Hanes, and Jeffrey D. Rothstein

Perineuronal Net Formation during the Critical Period for Neuronal Maturation in the Hypothalamic Arcuate Nucleus, Zaman Mirzadeh, Kimberly M. Alonge, Elaine Cabrales, Vicente Herranz-Pérez, Jarrad M. Scarlett, Jenny M. Brown, Rim Hassouna, Miles E. Matsen, Hong T. Nguyen, Jose Manuel Garcia-Verdugo, Lori M. Zeltser, and Michael W. Schwartz

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C9orf72 arginine-rich dipeptide proteins interact with ribosomal proteins in vivo to induce a toxic translational arrest that is rescued by eIF1A, Thomas G. Moens, Teresa Niccoli, Katherine M. Wilson, Magda L. Atilano, Nicol Birsa, Lauren M. Gittings, Benedikt V. Holbling, Miranda C. Dyson, Annora Thoeng, Jacob Neeves, Idoia Glaria, Lu Yu, Julia Bussmann, Erik Storkebaum, Mercedes Pardo, Jyoti S. Choudhary, Pietro Fratta, Linda Partridge, and Adrian M. Isaacs

Adar2 Mislocalization And Widespread Rna Editing Aberrations In C9Orf72-Mediated Als/Ftd, Stephen Moore, Eric Alsop, Ileana Lorenzini, Alexander Starr, Benjamin E. Rabichow, Emily Mendez, Jennifer L. Levy, Camelia Burciu, Rebecca Reiman, Jeannie Chew, Veronique V. Belzil, Dennis W. Dickson, Janice Robertson, Kim A. Staats, Justin K. Ichida, Leonard Petrucelli, Kendall Van Keuren-Jensen, and Rita Sattler

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Nerve Growth Factor Pathobiology During The Progression Of Alzheimer's Disease, Elliott J. Mufson, Scott E. Counts, Stephen D. Ginsberg, Laura Mahady, Sylvia E. Perez, Stephen M. Massa, Frank M. Longo, and Milos D. Ikonomovic

Astrocytic Changes With Aging And Alzheimer'S Disease-Type Pathology In Chimpanzees, Emily L. Munger, Melissa K. Edler, William D. Hopkins, John J. Ely, Joseph M. Erwin, Daniel P. Perl, Elliott J. Mufson, Patrick R. Hof, Chet C. Sherwood, and Mary Ann Raghanti

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Profiling the mouse brain endothelial transcriptome in health and disease models reveals a core blood-brain barrier dysfunction module, Roeben Nocon Munji, Allison Luen Soung, Geoffrey Aaron Weiner, Fabien Sohet, Bridgette Deanne Semple, Alpa Trivedi, Kayleen Gimlin, Masakazu Kotoda, Masaaki Korai, Sidar Aydin, Austin Batugal, Anne Christelle Cabangcala, Patrick Georg Schupp, Michael Clark Oldham, Tomoki Hashimoto, Linda J. Noble-Haeusslein, and Richard Daneman

GSTA4 mediates reduction of cisplatin ototoxicity in female mice., Hyo-Jin Park, Mi-Jung Kim, Christina Rothenberger, Ashok Kumar, Edith M Sampson, Dalian Ding, Chul Han, Karessa White, Kevin Boyd, Senthilvelan Manohar, Yong-Hwan Kim, Maria S Ticsa, Aaron S Gomez, Isabela Caicedo, Upal Bose, Paul J Linser, Takuya Miyakawa, Masaru Tanokura, Thomas C Foster, Richard Salvi, and Shinichi Someya

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Probing glioblastoma and its microenvironment using single-nucleus and single-cell sequencing, Sen Peng, Seungchan Kim, Harshil Dhruv, Sanhita Rath, Connor Vuong, Saumya Bollam, Jenny Eschbacher, Xishuang Dong, Shwetal Mehta, Nader Sanai, and Michael Berens

Frontal Cortex And Striatal Cellular And Molecular Pathobiology In Individuals With Down Syndrome With And Without Dementia, Sylvia E. Perez, Jennifer C. Miguel, Bin He, Michael Malek-Ahmadi, Eric E. Abrahamson, Milos D. Ikonomovic, Ira Lott, Eric Doran, Melissa J. Alldred, Stephen D. Ginsberg, and Elliott J. Mufson

Spectral organization of focal seizures within the thalamotemporal network, Diana Pizarro, Adeel Ilyas, Ganne Chaitanya, Emilia Toth, Auriana Irannejad, Andrew Romeo, Kristen O. Riley, Leonidas Iasemidis, and Sandipan Pati

Imaging Vascular And Hemodynamic Features Of The Brain Using Dynamic Susceptibility Contrast And Dynamic Contrast Enhanced Mri, C. Chad Quarles, Laura C. Bell, and Ashley M. Stokes

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Exosomal Dna Aptamer Targeting α-Synuclein Aggregates Reduced Neuropathological Deficits In A Mouse Parkinson'S Disease Model, Xiaoxi Ren, Yun Zhao, Fenqin Xue, Yan Zheng, Haixia Huang, Wei Wang, Yongchang Chang, Hui Yang, and Jianliang Zhang

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Neonatal Nicotine Exposure Primes Midbrain Neurons to a Dopaminergic Phenotype and Increases Adult Drug Consumption, Benedetto Romoli, Adrian F. Lozada, Ivette M. Sandoval, Fredric P. Manfredsson, Thomas S. Hnasko, Darwin K. Berg, and Davide Dulcis

Design and Assembly of CRISPR/Cas9 Lentiviral and rAAV Vectors for Targeted Genome Editing, Ivette M. Sandoval, Timothy J. Collier, and Fredric P. Manfredsson

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Multimodal production of adeno-associated virus, Ivette M. Sandoval, Nathan M. Kuhn, and Fredric P. Manfredsson

Comparing The Biomechanical Stability Of Cortical Screw Trajectory Versus Standard Pedicle Screw Trajectory For Short- And Long-Segment Posterior Fixation In 3-Column Thoracic Spinal Injury, Amey R. Savardekar, Nestor G. Rodriguez-Martinez, Anna G.U.S. Newcomb, Phillip M. Reyes, Hector Soriano-Baron, Steve W. Chang, Brian P. Kelly, and Neil R. Crawford

Moving Toward A Consensus Dsc-Mri Protocol: Validation Of A Low-Flip Angle Single-Dose Option As A Reference Standard For Brain Tumors, K. M. Schmainda, M. A. Prah, L. S. Hu, C. C. Quarles, N. Semmineh, S. D. Rand, J. M. Connelly, B. Anderies, Y. Zhou, Y. Liu, B. Logan, A. Stokes, G. Baird, and J. L. Boxerman

Regulation of dopamine neurotransmission from serotonergic neurons by ectopic expression of the dopamine D2 autoreceptor blocks levodopa-induced dyskinesia, Rhyomi C. Sellnow, Jordan H. Newman, Nicole Chambers, Anthony R. West, Kathy Steece-Collier, Ivette M. Sandoval, Matthew J. Benskey, Christopher Bishop, and Fredric P. Manfredsson

Potential Influences Of Gut Microbiota On The Formation Of Intracranial Aneurysm, Fumiaki Shikata, Kenji Shimada, Hiroki Sato, Taichi Ikedo, Atsushi Kuwabara, Hajime Furukawa, Masaaki Korai, Masakazu Kotoda, Kimihiko Yokosuka, Hiroshi Makino, Emma A. Ziegler, Daisuke Kudo, Michael T. Lawton, and Tomoki Hashimoto

Biomechanical implications of unilateral facetectomy, unilateral facetectomy plus partial contralateral facetectomy, and complete bilateral facetectomy in minimally invasive transforaminal interbody fusion., Laura A Snyder, Jennifer N Lehrman, Ram Kumar Menon, Jakub Godzik, Anna G U S Newcomb, and Brian P. Kelly

Biomechanical Effects Of An Oblique Lumbar Peek Cage And Posterior Augmentation, Hector Soriano-Baron, Anna G.U.S. Newcomb, Devika Malhotra, Eduardo Martinez del Campo, Atilio E. Palma, Nicholas Theodore, Neil R. Crawford, Brian P. Kelly, and Taro Kaibara

Early postmarket results with PulseRider for treatment of wide-necked intracranial aneurysms: a multicenter experience, Visish M. Srinivasan, Aditya Srivatsan, Alejandro M. Spiotta, Benjamin K. Hendricks, Andrew F. Ducruet, Felipe C. Albuquerque, Ajit Puri, Matthew R. Amans, Steven W. Hetts, Daniel L. Cooke, Christopher S. Ogilvy, Ajith J. Thomas, Alejandro Enriquez-Marulanda, Ansaar Rai, SoHyun Boo, Andrew P. Carlson, R Webster Crowley, Leonardo Rangel-Castilla, Giuseppe Lanzino, Peng Roc Chen, Orlando Diaz, Bradley N. Bohnstedt, Kyle P. O'Connor, Jan-Karl Burkhardt, Jeremiah N. Johnson, Stephen R. Chen, and Peter Kan

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Genetic silencing of striatal CaV1.3 prevents and ameliorates levodopa dyskinesia, Kathy Steece-Collier, Jennifer A. Stancati, Nicholas J. Collier, Ivette M. Sandoval, Natosha M. Mercado, Caryl E. Sortwell, Timothy J. Collier, and Fredric P. Manfredsson

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Primum non nocere: a call for balance when reporting on CTE, William Stewart, Kieren Allinson, Safa Al-Sarraj, Corbin Bachmeier, Karen Barlow, Antonio Belli, Mark P. Burns, Alan Carson, Fiona Crawford, Kristen Dams-O'Connor, Ramon Diaz-Arrastia, C. Edward Dixon, Brian L. Edlow, Scott Ferguson, Bruce Fischl, Rebecca D. Folkerth, Steve Gentleman, Christopher C. Giza, M. Sean Grady, Adel Helmy, Mark Herceg, Janice L. Holton, David Howell, Peter J. Hutchinson, Diego Iacono, Juan E. Iglesias, Milos D. Ikonomovic, Victoria E. Johnson, C. Dirk Keene, Julia K. Kofler, Vassilis E. Koliatsos, and Edward B. Lee

Systematic Assessment Of Multi-Echo Dynamic Susceptibility Contrast Mri Using A Digital Reference Object, Ashley M. Stokes, Natenael B. Semmineh, Ashley Nespodzany, Laura C. Bell, and C. Chad Quarles

Noninvasive Vagus Nerve Stimulation Prevents Ruptures And Improves Outcomes In A Model Of Intracranial Aneurysm In Mice, Tomoaki Suzuki, Tsubasa Takizawa, Yoshinobu Kamio, Tao Qin, Tomoki Hashimoto, Yukihiko Fujii, Yuichi Murayama, Aman B. Patel, and Cenk Ayata

Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia, Oliver H. Tam, Nikolay V. Rozhkov, Regina Shaw, Duyang Kim, Isabel Hubbard, Samantha Fennessey, Nadia Propp, Hemali Phatnani, Justin Kwan, Dhruv Sareen, James R. Broach, Zachary Simmons, Ximena Arcila-Londono, Edward B. Lee, Vivianna M. Van Deerlin, Neil A. Shneider, Ernest Fraenkel, Lyle W. Ostrow, Frank Baas, Noah Zaitlen, James D. Berry, Andrea Malaspina, Pietro Fratta, Gregory A. Cox, Leslie M. Thompson, Steve Finkbeiner, Efthimios Dardiotis, Timothy M. Miller, Siddharthan Chandran, Suvankar Pal, and Eran Hornstein

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A phase 0 trial of ribociclib in recurrent glioblastoma patients incorporating a tumor pharmacodynamic- And pharmacokinetic-guided expansion cohort, An Chi Tien, Jing Li, Xun Bao, Alanna Derogatis, Seongho Kim, Shwetal Mehta, and Nader Sanai

A three-dimensional (3D) organotypic microfluidic model for glioma stem cells - Vascular interactions, Danh Truong, Roberto Fiorelli, Eric S. Barrientos, Ernesto Luna Melendez, Nader Sanai, Shwetal Mehta, and Mehdi Nikkhah

Author Correction: C/EBPβ regulates delta-secretase expression and mediates pathogenesis in mouse models of Alzheimer's disease, Zhi-Hao Wang, Ke Gong, Xia Liu, Zhentao Zhang, Xiaoou Sun, Zheng Zachory Wei, Shan Ping Yu, Fredric P. Manfredsson, Ivette M. Sandoval, Peter F. Johnson, Jianping Jia, Jian-Zhi Wang, and Keqiang Ye

Deficiency in BDNF/TrkB Neurotrophic Activity Stimulates δ-Secretase by Upregulating C/EBPβ in Alzheimer's Disease, Zhi-Hao Wang, Jie Xiang, Xia Liu, Shan Ping Yu, Fredric P. Manfredsson, Ivette M. Sandoval, Shengxi Wu, Jian-Zhi Wang, and Keqiang Ye

Validity of a food and fluid exercise questionnaire for macronutrient intake during exercise against observations, Floris C. Wardenaar, Daan Hoogervorst, Nancy Van Der Burg, Joline Versteegen, Wonsuk Yoo, and Natasha Tasevska

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Distinctive Single-Channel Properties Of α4β2-Nicotinic Acetylcholine Receptor Isoforms, Maegan M. Weltzin, Andrew A. George, Ronald J. Lukas, and Paul Whiteaker

IL6 receptor(358)Ala variant and trans-signaling are disease modifiers in amyotrophic lateral sclerosis., Marlena Wosiski-Kuhn, Mac Robinson, Jane Strupe, Phonepasong Arounleut, Matthew Martin, James Caress, Michael Cartwright, Robert Bowser, Merit Cudkowicz, Carl Langefeld, Gregory A Hawkins, and Carol Milligan

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Nanocarriers Of Fe3O4 As A Novel Method For Delivery Of The Antineoplastic Agent Doxorubicin Into Hela Cells In Vitro, Kun Kun Xia, Yong Lyu, Wei Tang Yuan, Gui Xian Wang, Harrison Stratton, Shui Jun Zhang, and Jie Wu

Heterogeneity Of Cannabinoid Ligand-Induced Modulations In Intracellular Ca 2+ Signals Of Mouse Pancreatic Acinar Cells In Vitro, Kun kun Xia, Jian xin Shen, Ze bing Huang, Hui min Song, Ming Gao, De jie Chen, Shui jun Zhang, and Jie Wu

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Delta-secretase-cleaved Tau antagonizes TrkB neurotrophic signalings, mediating Alzheimer’s disease pathologies, Jie Xiang, Zhi Hao Wang, Eun Hee Ahn, Xia Liu, Shan Ping Yu, Fredric P. Manfredsson, Ivette M. Sandoval, Gong Ju, Shengxi Wu, and Keqiang Ye

Delta-secretase-cleaved Tau antagonizes TrkB neurotrophic signalings, mediating Alzheimer's disease pathologies, Jie Xiang, Zhi-Hao Wang, Eun Hee Ahn, Xia Liu, Shan-Ping Yu, Fredric P. Manfredsson, Ivette M. Sandoval, Gong Ju, Shengxi Wu, and Keqiang Ye

Reactivation Of Nonsense-Mediated Mrna Decay Protects Against C9Orf72 Dipeptide-Repeat Neurotoxicity, Wangchao Xu, Puhua Bao, Xin Jiang, Haifang Wang, Meiling Qin, Ruiqi Wang, Tao Wang, Yi Yang, Ileana Lorenzini, Lujian Liao, Rita Sattler, and Jin Xu

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Apolipoprotein E regulates mitochondrial function through the PGC-1α-sirtuin 3 pathway, Junxiang Yin, Megan Nielsen, Tanner Carcione, Shiping Li, and Jiong Shi

Role of matrix metalloproteinases in the pathogenesis of intracranial aneurysms, Xiaoran Zhang, William J. Ares, Philipp Taussky, Andrew F. Ducruet, and Ramesh Grandhi

Left Far Lateral Craniotomy for Clipping of a Posterior Inferior Cerebellar Artery Aneurysm, Xiaochun Zhao, Robert T. Wicks, Celene B. Mulholland, Andrew F. Ducruet, and Peter Nakaji

Submissions from 2018

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Sublethal Photodynamic Treatment Does Not Lead to Development of Resistance, Rawan Al-Mutairi, Artak Tovmasyan, Ines Batinic-Haberle, and Ludmil Benov

Porphyrin-Based SOD Mimic MnTnBu OE -2-PyP Inhibits Mechanisms of Aortic Valve Remodeling in Human and Murine Models of Aortic Valve Sclerosis, Wanda Anselmo, Emanuela Branchetti, Juan B. Grau, Gen Li, Salma Ayoub, Eric K. Lai, Nancy Rioux, Artak Tovmasyan, Jacqueline H. Fortier, Michael S. Sacks, Ines Batinic-Haberle, Stanley L. Hazen, Robert J. Levy, and Giovanni Ferrari

Diagnostic Accuracy of Somatosensory Evoked Potential Monitoring in Evaluating Neurological Complications During Endovascular Aneurysm Treatment, William J. Ares, Ramesh M. Grandhi, David M. Panczykowski, Gregory M. Weiner, Parthasarathy Thirumala, Miguel E. Habeych, Donald J. Crammond, Michael B. Horowitz, Brian T. Jankowitz, Ashutosh Jadhav, Tudor G. Jovin, Andrew F. Ducruet, and Jeffrey Balzer

ALSUntangled 41: “Eric Is Winning”, Yvonne Baker, Richard Bedlack, Paul Wicks, Meraida Polak, John Kissel, Carlayne Jackson, Mark Bromberg, Nicholas Maragakis, Terry Heiman-Patterson, Kathy Mitchell, Lucie Bruijn, Stephen Kolb, Paul Barkhaus, Jonathan Glass, James Caress, Tulio Bertorini, Eric Valor, Gregory Carter, Larry Phillips, Jeff Rothstein, Lyle Ostrow, Gregory Ringkamp, Michael Benatar, Fernando Vieira, Laurie Gutmann, Martina Wiedau, Carmel Armon, Michael Rivner, Sabrina Paganoni, Gleb Levitsky, and Kristiana Salmon

Artificial Intelligence In Neurodegenerative Disease Research: Use Of Ibm Watson To Identify Additional Rna-Binding Proteins Altered In Amyotrophic Lateral Sclerosis, Nadine Bakkar, Tina Kovalik, Ileana Lorenzini, Scott Spangler, Alix Lacoste, Kyle Sponaugle, Philip Ferrante, Elenee Argentinis, Rita Sattler, and Robert Bowser

In Vivo Neuroimaging And Behavioral Correlates In A Rat Model Of Chemotherapy-Induced Cognitive Dysfunction, Robert L. Barry, Nellie E. Byun, M. Noor Tantawy, Chase A. Mackey, George H. Wilson, Adam J. Stark, Michael P. Flom, Laura C. Gee, and C. Chad Quarles

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Mn porphyrin-based redox-active drugs: Differential effects as cancer therapeutics and protectors of normal tissue against oxidative injury, Ines Batinic-Haberle, Artak Tovmasyan, and Ivan Spasojevic

Silencing Alpha Synuclein in Mature Nigral Neurons Results in Rapid Neuroinflammation and Subsequent Toxicity, Matthew J. Benskey, Rhyomi C. Sellnow, Ivette M. Sandoval, Caryl E. Sortwell, Jack W. Lipton, and Fredric P. Manfredsson

RNA Nucleocytoplasmic Transport Defects in Neurodegenerative Diseases, Ashley Boehringer and Robert Bowser

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Subcentimeter epilepsy surgery targets by resting state functional magnetic resonance imaging can improve outcomes in hypothalamic hamartoma, Varina L. Boerwinkle, Stephen T. Foldes, Salvatore J. Torrisi, Hamy Temkit, William D. Gaillard, John F. Kerrigan, Virendra R. Desai, Jeffrey S. Raskin, Aditya Vedantam, Randa Jarrar, Korwyn Williams, Sandi Lam, Manish Ranjan, Janna S. Broderson, David Adelson, Angus A. Wilfong, and Daniel J. Curry

ALSUntangled 42: Elysium health's "basis"., Robert Bowser and ALSUntangled Group

ALSUntangled 44: curcumin., Robert Bowser and ALSUntangled Group

ALSUntangled 45: Antiretrovirals., Robert Bowser and ALSUntangled Group

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Manganese porphyrin redox state in endothelial cells: Resonance Raman studies and implications for antioxidant protection towards peroxynitrite, Sebastián Carballal, Valeria Valez, Damián Alvarez-Paggi, Artak Tovmasyan, Ines Batinic-Haberle, Gerardo Ferrer-Sueta, Daniel H. Murgida, and Rafael Radi

Erratum to "Manganese porphyrin redox state in endothelial cells: Resonance Raman studies and implications for antioxidant protection towards peroxynitrite" [Free Radic. Biol. Med. 126 (2018) 379-392], Sebastián Carballal, Valeria Valez, Damián Alvarez-Paggi, Artak Tovmasyan, Ines Batinic-Haberle, Gerardo Ferrer-Sueta, Daniel H. Murgida, and Rafael Radi

The Segmental Distribution Of Cervical Range Of Motion: A Comparison Of Acdf Versus Tdr-C, Steve W. Chang, Michael A. Bohl, Brian P. Kelly, and Chip Wade

Pharmacological And Functional Comparisons Of α6/α3β2β3-Nachrs And α4β2-Nachrs Heterologously Expressed In The Human Epithelial Sh-Ep1 Cell Line, De jie Chen, Fen fei Gao, Xiao Kuang Ma, Gang gang Shi, Yuan bing Huang, Quang xi Su, Sterling Sudweeks, Ming Gao, Turner Dharshaun, Jason Brek Eaton, Yong Chang, J. Michael Mcintosh, Ronald J. Lukas, Paul Whiteaker, Scott C. Steffensen, and Jie Wu

Tdp-43 Pathology Disrupts Nuclear Pore Complexes And Nucleocytoplasmic Transport In Als/Ftd, Ching Chieh Chou, Yi Zhang, Mfon E. Umoh, Spencer W. Vaughan, Ileana Lorenzini, Feilin Liu, Melissa Sayegh, Paul G. Donlin-Asp, Yu Han Chen, Duc M. Duong, Nicholas T. Seyfried, Maureen A. Powers, Thomas Kukar, Chadwick M. Hales, Marla Gearing, Nigel J. Cairns, Kevin B. Boylan, Dennis W. Dickson, Rosa Rademakers, Yong Jie Zhang, Leonard Petrucelli, Rita Sattler, Daniela C. Zarnescu, Jonathan D. Glass, and Wilfried Rossoll

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Intermittent Fasting Confers Protection in CNS Autoimmunity by Altering the Gut Microbiota, Francesca Cignarella, Claudia Cantoni, Laura Ghezzi, Amber Salter, Yair Dorsett, Lei Chen, Daniel Phillips, George M. Weinstock, Luigi Fontana, Anne H. Cross, Yanjiao Zhou, and Laura Piccio

Post-Irradiation Treatment with a Superoxide Dismutase Mimic, MnTnHex-2-PyP, Mitigates Radiation Injury in the Lungs of Non-Human Primates after Whole-Thorax Exposure to Ionizing Radiation, John Mark Cline, Greg Dugan, John Daniel Bourland, Donna L. Perry, Joel D. Stitzel, Ashley A. Weaver, Chen Jiang, Artak Tovmasyan, Kouros Owzar, Ivan Spasojevic, Ines Batinic-Haberle, and Zeljko Vujaskovic

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Endovascular Biopsy: In Vivo Cerebral Aneurysm Endothelial Cell Sampling and Gene Expression Analysis, Daniel L. Cooke, David B. McCoy, Van V. Halbach, Steven W. Hetts, Matthew R. Amans, Christopher F. Dowd, Randall T. Higashida, Devon Lawson, Jeffrey Nelson, Chih Yang Wang, Helen Kim, Zena Werb, Charles McCulloch, Tomoki Hashimoto, Hua Su, and Zhengda Sun

Tissue Sodium Content is Elevated in the Skin and Subcutaneous Adipose Tissue in Women with Lipedema., Rachelle Crescenzi, Adriana Marton, Paula M C Donahue, Helen B Mahany, Sarah K Lants, Ping Wang, Joshua A Beckman, Manus J Donahue, and Jens Titze

In Vitro Biomechanical Evaluation Of A Novel Minimally Invasive Sacroiliac Joint Fixation Device, William W. Cross, Sigurd H. Berven, Nick Slater, Jennifer N. Lehrman, Anna G.U.S. Newcomb, and Brian P. Kelly

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Remapping cortical modulation for electrocorticographic brain-computer interfaces: a somatotopy-based approach in individuals with upper-limb paralysis, Alan D. Degenhart, Shivayogi V. Hiremath, Ying Yang, Stephen Foldes, Jennifer L. Collinger, Michael Boninger, Elizabeth C. Tyler-Kabara, and Wei Wang

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Language lateralization with resting-state and task-based functional MRI in pediatric epilepsy, Virendra R. Desai, Aditya Vedantam, Sandi K. Lam, Lucia Mirea, Stephen T. Foldes, Daniel J. Curry, P David Adelson, Angus A. Wilfong, and Varina L. Boerwinkle

In Reply to the Letter to the Editor "C2 Spinous Process Screws", NingNing Dou, Jennifer N. Lehrman, Anna G. Newcomb, and Brian P. Kelly

A Novel C2 Screw Trajectory: Preliminary Anatomic Feasibility And Biomechanical Comparison, Ning Ning Dou, Jennifer N. Lehrman, Anna G.U.S. Newcomb, and Brian P. Kelly

Commentary on 'Inflammatory changes in the aneurysm wall: a review', Andrew F. Ducruet

Microglia Changes Associated To Alzheimer'S Disease Pathology In Aged Chimpanzees, Melissa K. Edler, Chet C. Sherwood, Richard S. Meindl, Emily L. Munger, William D. Hopkins, John J. Ely, Joseph M. Erwin, Daniel P. Perl, Elliott J. Mufson, Patrick R. Hof, and Mary Ann Raghanti

A survey of intracranial aneurysm treatment practices among United States physicians, Kyle M. Fargen, Hector E. Soriano-Baron, Julia T. Rushing, William Mack, J Mocco, Felipe Albuquerque, Andrew F. Ducruet, Maxim Mokin, Italo Linfante, Stacey Q. Wolfe, John A. Wilson, and Joshua A. Hirsch

Introducing a Novel Method of Intravascular Adeno-associated Virus-mediated Gene Delivery., Z H Fazal, K Hosaka, F P Manfredsson, and B L Hoh

Targetable Gene Fusions Associate With the IDH Wild-Type Astrocytic Lineage in Adult Gliomas, Sherise D. Ferguson, Shouhao Zhou, Jason T. Huse, John F. de Groot, Joanne Xiu, Deepa S. Subramaniam, Shwetal Mehta, Zoran Gatalica, Jeffrey Swensen, Nader Sanai, David Spetzler, and Amy B. Heimberger

Multimorbidity patterns and associations with functional limitations among an aging population in prison, Madison L. Gates, Elizabeth G. Hunter, Vivian Dicks, Peace N. Jessa, Veronica Walker, and Wonsuk Yoo

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Representing Diversity In The Dish: Using Patient-Derived In Vitro Models To Recreate The Heterogeneity Of Neurological Disease, Layla T. Ghaffari, Alexander Starr, Andrew T. Nelson, and Rita Sattler

Biomechanical evaluation of interbody fixation with secondary augmentation: lateral lumbar interbody fusion versus posterior lumbar interbody fusion, Jakub Godzik, Samuel Kalb, Marco T. Reis, Phillip M. Reyes, Vaneet Singh, Anna G. Newcomb, Steve W. Chang, Brian P. Kelly, and Neil R. Crawford

Biomechanical Stability Afforded By Unilateral Versus Bilateral Pedicle Screw Fixation With And Without Interbody Support Using Lateral Lumbar Interbody Fusion, Jakub Godzik, Eduardo Martinez-del-Campo, Anna G.U.S. Newcomb, Marco T. Reis, Luis Perez-Orribo, Alexander C. Whiting, Vaneet Singh, Brian P. Kelly, and Neil R. Crawford

A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment, Amelie Griveau, Giorgio Seano, Samuel J. Shelton, Robert Kupp, Arman Jahangiri, Kirsten Obernier, Shanmugarajan Krishnan, Olle R. Lindberg, Tracy J. Yuen, An-Chi Tien, Jennifer K. Sabo, Nancy Wang, Ivy Chen, Jonas Kloepper, Louis Larrouquere, Mitrajit Ghosh, Itay Tirosh, Emmanuelle Huillard, Arturo Alvarez-Buylla, Michael C. Oldham, Anders I. Persson, William A. Weiss, Tracy T. Batchelor, Anat Stemmer-Rachamimov, Mario L. Suvà, Joanna J. Phillips, Manish K. Aghi, Shwetal Mehta, Rakesh K. Jain, and David H. Rowitch

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Hypertonic Stress Causes Cytoplasmic Translocation of Neuronal, but Not Astrocytic, FUS due to Impaired Transportin Function, Eva-Maria Hock, Zuzanna Maniecka, Marian Hruska-Plochan, Stefan Reber, Florent Laferrière, Sonu Sahadevan M K, Helena Ederle, Lauren Gittings, Lucas Pelkmans, Luc Dupuis, Tammaryn Lashley, Marc-David Ruepp, Dorothee Dormann, and Magdalini Polymenidou

A Novel Microbiosensor Microarray for Continuous Monitoring of Gamma-Aminobutyric Acid in Real-Time, Imran Hossain, Chao Tan, Phillip T. Doughty, Gaurab Dutta, Teresa A. Murray, Shabnam Siddiqui, Leonidas Iasemidis, and Prabhu U. Arumugam

pH driven precipitation of quisinostat onto PLA-PEG nanoparticles enables treatment of intracranial glioblastoma, Kyle T. Householder, Danielle M. DiPerna, Eugene P. Chung, Anne Rosa Luning, Duong T. Nguyen, Sarah E. Stabenfeldt, Shwetal Mehta, and Rachael W. Sirianni