The Barrow Neurological Institute is proud of its reputation as a medical research facility and is home to some of the most sophisticated research programs outside of an academic setting in the Southwestern United States. Researchers in the Barrow Neurosurgery Research Center are devoted to learning more about the causes of and treatments for a wide range of disorders, such as stroke, aneurysms, spinal cord injury, and hydrocephalus. Our research has led to treatments that are being used around the world. Within the Department are neurosurgeons who subspecialize in cerebrovascular and skull base, functional and stereotactic, pediatric, spine, tumor, and endovascular neurosurgery.
Physicians, scientists, and expert clinical staff come together with a commitment to developing new techniques for the prevention, diagnosis, treatment, and rehabilitation of neurological illnesses and injuries. The leadership of internationally respected physicians keeps Barrow at the forefront of neuroscience. The compassionate expertise of its extensive staff of nurses, technologists, therapists and support personnel is evident in every aspect of care provided.
Our mission is to advance the knowledge and practice of medicine in neuroscience through basic and clinical research, education of medical professionals, and innovation in clinical techniques and technology.
Submissions from 2022
The Gut Microbiome-Brain Crosstalk in Neurodegenerative Diseases, Laura Ghezzi, Claudia Cantoni, Emanuela Rotondo, and Daniela Galimberti
Optimizing Cervicothoracic Junction Biomechanics after C7 Pedicle Subtraction Osteotomy: A Cadaveric Study of Stability and Rod Strain, Jakub Godzik, Jennifer N. Lehrman, S Harrison Farber, Bernardo de Andrada Pereira, Anna G. Sawa, Christopher P. Ames, Heiko Koller, Kevin Lee, Jay D. Turner, and Brian P. Kelly
Factors Contributing to Spinal Cord Stimulation Outcomes for Chronic Pain, Dakota T. Graham, Margaret Lambert, Zaman Mirzadeh, and Francisco A. Ponce
Microscale electrophysiological functional connectivity in human cortico-basal ganglia network, Ashley C. Guest, Kevin J. O'Neill, Dakota Graham, Zaman Mirzadeh, Francisco A. Ponce, and Bradley Greger
PNJ scaffolds promote microenvironmental regulation of glioblastoma stem-like cell enrichment and radioresistance, John M. Heffernan, James B. McNamara, Brent L. Vernon, Shwetal Mehta, and Rachael W. Sirianni
Folic Acid Improves Parkin-Null Phenotypes and Transiently Reduces Vulnerable Dopaminergic Neuron Mitochondrial Hydrogen Peroxide Levels and Glutathione Redox Equilibrium, Katherine L. Houlihan, Petros P. Keoseyan, Amber N. Juba, Tigran Margaryan, Max E. Voss, Alexander M. Babaoghli, Justin M. Norris, Greg J. Adrian, Artak Tovmasyan, and Lori M. Buhlman
Posterior cingulate cortex reveals an expression profile of resilience in cognitively intact elders, Christy M. Kelley, Stephen D. Ginsberg, Winnie S. Liang, Scott E. Counts, and Elliott J. Mufson
Use of digital imaging correlation techniques for full-field strain distribution analysis of implantable devices and tissue in spinal biomechanics research, Brian P. Kelly, Casey R. Silva, Jennifer N. Lehrman, Anna G. Sawa, Bernardo de Andrada Pereira, Jakub Godzik, and Jay D. Turner
Assessing the volume-outcome relationship of carotid artery stenting in nationwide administrative data: a challenge of patient population bias, Stefan W. Koester, Tyler S. Cole, Anna R. Kimata, Kevin L. Ma, Dimitri Benner, Joshua S. Catapano, Kavelin Rumalla, Michael T. Lawton, Andrew F. Ducruet, and Felipe C. Albuquerque
Influence of Spinal Deformity Construct Design on Adjacent-Segment Biomechanics, Robert M. Koffie, Bernardo de Andrada Pereira, Jennifer N. Lehrman, Jakub Godzik, Anna G. Sawa, Shashank V. Gandhi, Brian P. Kelly, Juan S. Uribe, and Jay D. Turner
Predictors of Ischemic Complication in Anterior Choroidal Artery Aneurysm Repair., Takuma Maeda, Hidetoshi Ooigawa, Kaima Suzuki, Hiroki Sato, Satoshi Iihoshi, Shinya Kohyama, and Hiroki Kurita
Simultaneous determination of LY3214996, abemaciclib, and M2 and M20 metabolites in human plasma, cerebrospinal fluid, and brain tumor by LC-MS/MS, Tigran Margaryan, Mackenna Elliott, Nader Sanai, and Artak Tovmasyan
2021 Workshop: Neurodegenerative Diseases in the Gut-Brain Axis - Parkinson's Disease, Gary M. Mawe, Kirsteen N. Browning, Fredric P. Manfredsson, Michael Camilleri, Frank A. Hamilton, Jonathan A. Hollander, Beth-Anne Sieber, Patricia Greenwel, Terez Shea-Donohue, and John W. Wiley
A Phase 0 Trial of Ceritinib in Patients with Brain Metastases and Recurrent Glioblastoma, Shwetal Mehta, Roberto Fiorelli, Xun Bao, Chelsea Pennington-Krygier, Alanna Derogatis, Seongho Kim, Wonsuk Yoo, Jing Li, and Nader Sanai
Editorial: Mechanisms of Action in Neurodegenerative Proteinopathies, Sean J. Miller, Selina Wray, Rita Sattler, and Can Zhang
Central Nervous System Control of Glucose Homeostasis: A Therapeutic Target for Type 2 Diabetes?, Zaman Mirzadeh, Chelsea L. Faber, and Michael W. Schwartz
Spatial-temporal analysis of cerebral infarction mortality in Hokkaido, Japan: an ecological study using a conditional autoregressive model, Kazuki Ohashi, Toshiya Osanai, Kensuke Fujiwara, Takumi Tanikawa, Yuji Tani, Soichiro Takamiya, Hirotaka Sato, Yasuhiro Morii, Kyohei Bando, and Katsuhiko Ogasawara
The CSF in neurosarcoidosis contains consistent clonal expansion of CD8 T cells, but not CD4 T cells, Michael A. Paley, Brandi J. Baker, S Richard Dunham, Nicole Linskey, Claudia Cantoni, Kenneth Lee, Lynn M. Hassman, Jennifer Laurent, Elisha D. Roberson, David B. Clifford, and Wayne M. Yokoyama
Pedicle Subtraction Osteotomy Construct Optimization: A Cadaveric Study of Various Multirod and Interbody Configurations, Bernardo de Pereira, Jakub Godzik, Jennifer N. Lehrman, Anna G. Sawa, Randall J. Hlubek, Juan S. Uribe, Brian P. Kelly, and Jay D. Turner
Biomechanical Effects of Proximal Polyetheretherketone Rod Extension on the Upper Instrumented and Adjacent Levels in a Human Long-Segment Construct: A Cadaveric Model, Bernardo de Pereira, Jennifer N. Lehrman, Anna G. Sawa, Piyanat Wangsawatwong, Jakub Godzik, David S. Xu, Jay D. Turner, Brian P. Kelly, and Juan S. Uribe
Rotenone induces regionally distinct α-synuclein protein aggregation and activation of glia prior to loss of dopaminergic neurons in C57Bl/6 mice, Savannah M. Rocha, Collin M. Bantle, Tawfik Aboellail, Debotri Chatterjee, Richard J. Smeyne, and Ronald B. Tjalkens
A Novel Glucocorticoid and Androgen Receptor Modulator Reduces Viral Entry and Innate Immune Inflammatory Responses in the Syrian Hamster Model of SARS-CoV-2 Infection, Savannah M. Rocha, Anna C. Fagre, Amanda S. Latham, Jason E. Cummings, Tawfik A. Aboellail, Philip Reigan, Devin A. Aldaz, Casey P. McDermott, Katriana A. Popichak, Rebekah C. Kading, Tony Schountz, Neil D. Theise, Richard A. Slayden, and Ronald B. Tjalkens
Correlation of T1- to T2-weighted signal intensity ratio with T1- and T2-relaxation time and IDH mutation status in glioma, Takahiro Sanada, Shota Yamamoto, Mio Sakai, Toru Umehara, Hirotaka Sato, Masato Saito, Nobuyuki Mitsui, Satoru Hiroshima, Ryogo Anei, Yonehiro Kanemura, Mishie Tanino, Katsuyuki Nakanishi, Haruhiko Kishima, and Manabu Kinoshita
The health economic effects of an imaging technology-based telemedicine system for rural neuro-emergency patient care, Hirotaka Sato, Manabu Kinoshita, Yuji Tani, Teruo Kimura, Toshiya Osanai, Hiroaki Osanai, and Katsuhiko Ogasawara
Left Atrial Volume Index as a Predictor for Large-Vessel Occlusion in Cardiogenic Cerebral Infarction: A Single-Center Cohort Study, Hirotaka Sato, Masato Saito, Nobuyuki Mitsui, Satoru Hiroshima, Jun Sawada, Kazumi Akasaka, and Manabu Kinoshita
Imaging Glioblastoma With F-Fluciclovine Amino Acid Positron Emission Tomography, Matthew L. Scarpelli, Debbie R. Healey, Shwetal Mehta, and C Chad Quarles
Cytochemical Characterization of Cerebrospinal Fluid Macrophage Inclusions in Pediatric Patients Receiving Intrathecal Nusinersen (SPINRAZA®) for Spinal Muscular Atrophy, Kristian T. Schafernak, Jeffrey R. Jacobsen, Dulce Hernandez, Robin D. Kaye, and Sylvia E. Perez
Amyotrophic Lateral Sclerosis Clinical Trials and Interpretation of Functional End Points and Fluid Biomarkers: A Review, Jeremy M. Shefner, Richard Bedlack, Jinsy A. Andrews, James D. Berry, Robert Bowser, Robert Brown, Jonathan D. Glass, Nicholas J. Maragakis, Timothy M. Miller, Jeffrey D. Rothstein, and Merit E. Cudkowicz
Rapid parameter estimation for selective inversion recovery myelin imaging using an open-source Julia toolkit, Nicholas J. Sisco, Ping Wang, Ashley M. Stokes, and Richard D. Dortch
Interpretable surface-based detection of focal cortical dysplasias: a Multi-centre Epilepsy Lesion Detection study, Hannah Spitzer, Mathilde Ripart, Kirstie Whitaker, Felice D'Arco, Kshitij Mankad, Andrew A. Chen, Antonio Napolitano, Luca De Palma, Alessandro De Benedictis, Stephen Foldes, Zachary Humphreys, Kai Zhang, Wenhan Hu, Jiajie Mo, Marcus Likeman, Shirin Davies, Christopher Güttler, Matteo Lenge, Nathan T. Cohen, Yingying Tang, Shan Wang, Aswin Chari, Martin Tisdall, Nuria Bargallo, Estefanía Conde-Blanco, Jose Carlos Pariente, Saül Pascual-Diaz, Ignacio Delgado-Martínez, Carmen Pérez-Enríquez, Ilaria Lagorio, Eugenio Abela, and Nandini Mullatti
Challenging access during flow diversion treatment of a giant cavernous ICA aneurysm, Visish M. Srinivasan, Joelle N. Hartke, Joshua S. Catapano, Ethan A. Winkler, Ashutosh P. Jadhav, Felipe C. Albuquerque, and Andrew F. Ducruet
ALSUntangled #64: butyrates, Yuyao Sun, Richard Bedlack, Carmel Armon, Morgan Beauchamp, Tulio Bertorini, Robert Bowser, Mark Bromberg, James Caress, Gregory Carter, Jesse Crayle, Merit E. Cudkowicz, Jonathan D. Glass, Carlayne Jackson, Isaac Lund, Sarah Martin, Sabrina Paganoni, Gary Pattee, Dylan Ratner, Kristiana Salmon, and Paul Wicks
Suppression of mutant C9orf72 expression by a potent mixed backbone antisense oligonucleotide, Hélène Tran, Michael P. Moazami, Huiya Yang, Diane McKenna-Yasek, Catherine L. Douthwright, Courtney Pinto, Jake Metterville, Minwook Shin, Nitasha Sanil, Craig Dooley, Ajit Puri, Alexandra Weiss, Nicholas Wightman, Heather Gray-Edwards, Miklos Marosfoi, Robert M. King, Thomas Kenderdine, Daniele Fabris, Robert Bowser, Jonathan K. Watts, and Robert H. Brown
Neurogenesis and neuronal differentiation in the postnatal frontal cortex in Down syndrome, Emma C. Utagawa, David G. Moreno, Kristian T. Schafernak, Nicoleta C. Arva, Michael H. Malek-Ahmadi, Elliott J. Mufson, and Sylvia E. Perez
Atlas of lesion locations and postsurgical seizure freedom in focal cortical dysplasia: A MELD study, Konrad Wagstyl, Kirstie Whitaker, Armin Raznahan, Jakob Seidlitz, Petra E. Vértes, Stephen Foldes, Zachary Humphreys, Wenhan Hu, Jiajie Mo, Marcus Likeman, Shirin Davies, Matteo Lenge, Nathan T. Cohen, Yingying Tang, Shan Wang, Mathilde Ripart, Aswin Chari, Martin Tisdall, Nuria Bargallo, Estefanía Conde-Blanco, Jose Carlos Pariente, Saül Pascual-Diaz, Ignacio Delgado-Martínez, Carmen Pérez-Enríquez, Ilaria Lagorio, Eugenio Abela, Nandini Mullatti, Jonathan O'Muircheartaigh, Katy Vecchiato, Yawu Liu, Maria Caligiuri, and Ben Sinclair
Intrathecal amyloid-beta oligomer administration increases tau phosphorylation in the medial temporal lobe in the African green monkey: a nonhuman primate model of Alzheimer's disease, Dustin R. Wakeman, Michael R. Weed, Sylvia E. Perez, Erika N. Cline, Kirsten L. Viola, Kyle C. Wilcox, David S. Moddrelle, Ernell Z. Nisbett, Anish M. Kurian, Amanda F. Bell, Ricaldo Pike, Peer B. Jacobson, William L. Klein, Elliott J. Mufson, Matthew S. Lawrence, and John D. Elsworth
Avoiding the Radial Paradox: Neuroendovascular Femoral Access Outcomes After Radial Access Adoption, D Andrew Wilkinson, Neil Majmundar, Joshua S. Catapano, Tyler S. Cole, Jacob F. Baranoski, Benjamin K. Hendricks, Daniel D. Cavalcanti, Vance L. Frederickson, Andrew F. Ducruet, and Felipe C. Albuquerque
Transradial cerebral angiography becomes more efficient than transfemoral angiography: lessons from 500 consecutive angiograms, D Andrew Wilkinson, Neil Majmundar, Joshua S. Catapano, Vance L. Fredrickson, Daniel D. Cavalcanti, Jacob F. Baranoski, Caleb Rutledge, Andrew F. Ducruet, and Felipe C. Albuquerque
Submissions from 2021
Multimodal Assessment of Cerebral Autoregulation and Autonomic Function After Pediatric Cerebral Arteriovenous Malformation Rupture, Brian Appavu, Stephen Foldes, Brian T. Burrows, Austin Jacobson, Todd Abruzzo, Varina Boerwinkle, Anthony Willyerd, Tara Mangum, Vishal Gunnala, Iris Marku, and P D. Adelson
Treatment Timing, EEG, Neuroimaging, and Outcomes After Acute Necrotizing Encephalopathy in Children, Brian Appavu, Stephen Foldes, Jordana Fox, Sheetal Shetty, Ann Oh, Freddy Bassal, Iris Marku, Tara Mangum, Varina Boerwinkle, Derek Neilson, and Michael Kruer
Association of Outcomes with Model-Based Indices of Cerebral Autoregulation After Pediatric Traumatic Brain Injury, Brian Appavu, M 'Hamed Temkit, Stephen Foldes, Brian T. Burrows, Michael Kuwabara, Austin Jacobson, and P David Adelson
The M1311V variant of ATP7A is associated with impaired trafficking and copper homeostasis in models of motor neuron disease, Nadine Bakkar, Alexander Starr, Benjamin E. Rabichow, Ileana Lorenzini, Zachary T. McEachin, Robert Kraft, Matthew Chaung, Sam Macklin-Isquierdo, Taylor Wingfield, Briggs Carhart, Nathan Zahler, Wen Hsuan Chang, Gary J. Bassell, Alexandre Betourne, Nicholas Boulis, Samuel V. Alworth, Justin K. Ichida, Paul R. August, Daniela C. Zarnescu, Rita Sattler, and Robert Bowser
Manganese exposure in juvenile C57BL/6 mice increases glial inflammatory responses in the substantia nigra following infection with H1N1 influenza virus, Collin M. Bantle, C Tenley French, Jason E. Cummings, Shankar Sadasivan, Kevin Tran, Richard A. Slayden, Richard J. Smeyne, and Ronald B. Tjalkens
Astrocyte inflammatory signaling mediates α-synuclein aggregation and dopaminergic neuronal loss following viral encephalitis, Collin M. Bantle, Savannah M. Rocha, C Tenley French, Aaron T. Phillips, Kevin Tran, Kenneth E. Olson, Todd A. Bass, Tawfik Aboellail, Richard J. Smeyne, and Ronald B. Tjalkens
Quantitative protein expression of blood-brain barrier transporters in the vasculature of brain metastases of patients with lung and breast cancer, Xun Bao, Jianmei Wu, Jun Jiang, An-Chi Tien, Nader Sanai, and Jing Li
H2O2-Driven Anticancer Activity of Mn Porphyrins and the Underlying Molecular Pathways, Ines Batinic-Haberle, Artak Tovmasyan, Zhiqing Huang, Weina Duan, Li Du, Sharareh Siamakpour-Reihani, Zhipeng Cao, Huaxin Sheng, Ivan Spasojevic, and Angeles Alvarez Secord
ALSUntangled #60: light therapy, Richard Bedlack, Paul Barkhaus, Ben Barnes, Michael Bereman, Tulio Bertorini, Gregory Carter, Jesse Crayle, Sky Kihuwa-Mani, Robert Bowser, Pamela Kittrell, Christopher McDermott, Gary Pattee, Kristiana Salmon, and Paul Wicks
Molecular Imaging of Glucose Metabolism for Intraoperative Fluorescence Guidance During Glioma Surgery, Evgenii Belykh, Jubran H. Jubran, Laeth L. George, Liudmila Bardonova, Deborah R. Healey, Joseph F. Georges, Chad C. Quarles, Jennifer M. Eschbacher, Shwetal Mehta, Adrienne C. Scheck, Peter Nakaji, and Mark C. Preul
Neurosurgical Treatments for Cancer Pain, Sharona Ben-Haim, Zaman Mirzadeh, and William S. Rosenberg
Systematic assessment of the impact of DTI methodology on fractional anisotropy measures in Alzheimer’s disease, Maurizio Bergamino, Elizabeth G. Keeling, Ryan R. Walsh, and Ashley M. Stokes
Free-water diffusion tensor imaging improves the accuracy and sensitivity of white matter analysis in Alzheimer’s disease, Maurizio Bergamino, Ryan R. Walsh, and Ashley M. Stokes
Radicava/Edaravone Findings in Biomarkers From Amyotrophic Lateral Sclerosis (REFINE-ALS): Protocol and Study Design, James Berry, Benjamin Brooks, Angela Genge, Terry Heiman-Patterson, Stanley Appel, Michael Benatar, Robert Bowser, Merit Cudkowicz, Clifton Gooch, Jeremy Shefner, Jurjen Westra, Wendy Agnese, Charlotte Merrill, Sally Nelson, and Stephen Apple
Complement C3a receptor-mediated vascular dysfunction: A complex interplay between aging and neurodegeneration, Kanchan Bhatia, Saif Ahmad, Adam Kindelin, and Andrew F. Ducruet
Complement C3a receptor-mediated vascular dysfunction: a complex interplay between aging and neurodegeneration., Kanchan Bhatia, Saif Ahmad, Adam Kindelin, and Andrew F. Ducruet
Trajectories of stroke recovery of impairment, function, and quality of life in response to 12-month mobility and fitness intervention, Catherine Boissoneault, Dorian K. Rose, Tyler Grimes, Michael F. Waters, Anna Khanna, Somnath Datta, and Janis J. Daly
Cell type-specific modulation of healthspan by Forkhead family transcription factors in the nervous system, Ekin Bolukbasi, Nathaniel S. Woodling, Dobril K. Ivanov, Jennifer Adcott, Andrea Foley, Arjunan Rajasingam, Lauren M. Gittings, Benjamin Aleyakpo, Teresa Niccoli, Janet M. Thornton, and Linda Partridge
ALSUntangled 55: vitamin E (α-tocopherol)., Robert Bowser and ALSUntangled Group
ALSUntangled 57: Vinpocetine., Robert Bowser and ALSUntangled Group
Nonredundant, isoform-specific roles of HDAC1 in glioma stem cells, Costanza Lo Cascio, James B. McNamara, Ernesto L. Melendez, Erika M. Lewis, Matthew E. Dufault, Nader Sanai, Christopher L. Plaisier, and Shwetal Mehta
Middle meningeal artery embolization for chronic subdural hematoma: an institutional technical analysis, Joshua S. Catapano, Andrew F. Ducruet, Candice L. Nguyen, Jacob F. Baranoski, Tyler S. Cole, Neil Majmundar, D Andrew Wilkinson, Vance L. Fredrickson, Daniel D. Cavalcanti, and Felipe C. Albuquerque
Corrigendum: Middle Meningeal Artery Embolization for Chronic Subdural Hematoma, Joshua S. Catapano, Candice L. Nguyen, Andre A. Wakim, Felipe C. Albuquerque, and Andrew F. Ducruet
Enhanced CNS transduction from AAV.PHP.eB infusion into the cisterna magna of older adult rats compared to AAV9, Diptaman Chatterjee, David J. Marmion, Jodi L. McBride, Fredric P. Manfredsson, David Butler, Anne Messer, and Jeffrey H. Kordower
Netrin-1 receptor UNC5C cleavage by active δ-secretase enhances neurodegeneration, promoting Alzheimer's disease pathologies, Guiqin Chen, Seong Su Kang, Zhihao Wang, Eun Hee Ahn, Yiyuan Xia, Xia Liu, Ivette M. Sandoval, Fredric P. Manfredsson, Zhaohui Zhang, and Keqiang Ye
α-Synuclein antisense oligonucleotides as a disease-modifying therapy for Parkinson’s disease, Tracy A. Cole, Hien Zhao, Timothy J. Collier, Ivette Sandoval, Caryl E. Sortwell, Kathy Steece-Collier, Brian F. Daley, Alix Booms, Jack Lipton, Mackenzie Welch, Melissa Berman, Luke Jandreski, Danielle Graham, Andreas Weihofen, Stephanie Celano, Emily Schulz, Allyson Cole-Strauss, Esteban Luna, Duc Quach, Apoorva Mohan, C. Frank Bennett, Eric E. Swayze, Holly B. Kordasiewicz, Kelvin C. Luk, and Katrina L. Paumier
A Low-Cost, Autonomous Gait Detection and Estimation System for Analyzing Gait Impairments in Mice, Pranav U. Damale, Edwin K. Chong, Sean L. Hammond, and Ronald B. Tjalkens
Biomechanical effects of a novel posteriorly placed sacroiliac joint fusion device integrated with traditional lumbopelvic long-construct instrumentation, Bernardo de Andrada Pereira, Jennifer N. Lehrman, Anna G. Sawa, Derek P. Lindsey, Scott A. Yerby, Jakub Godzik, Alexis M. Waguespack, Juan S. Uribe, and Brian P. Kelly
Influence of Lumbar Lordosis on Posterior Rod Strain in Long-Segment Construct During Biomechanical Loading: A Cadaveric Study, Bernardo de Andrada Pereira, Anna G. Sawa, Jakub Godzik, Jennifer N. Lehrman, Juan S. Uribe, Jay D. Turner, and Brian P. Kelly
Leptin receptor neurons in the dorsomedial hypothalamus regulate diurnal patterns of feeding, locomotion, and metabolism, Chelsea L. Faber, Jennifer D. Deem, Bao Anh Phan, Tammy P. Doan, Kayoko Ogimoto, Zaman Mirzadeh, Michael W. Schwartz, and Gregory J. Morton
SARS-CoV-2 infection, neuropathogenesis and transmission among deer mice: Implications for spillback to New World rodents, Anna Fagre, Juliette Lewis, Miles Eckley, Shijun Zhan, Savannah M. Rocha, Nicole R. Sexton, Bradly Burke, Brian Geiss, Olve Peersen, Todd Bass, Rebekah Kading, Joel Rovnak, Gregory D. Ebel, Ronald B. Tjalkens, Tawfik Aboellail, and Tony Schountz
Case Study: Mapping Evoked Fields in Primary Motor and Sensory Areas Magnetoencephalography in Tetraplegia, Stephen T. Foldes, Santosh Chandrasekaran, Joseph Camerone, James Lowe, Richard Ramdeo, John Ebersole, and Chad E. Bouton
Transdermal Electrical Neuromodulation for Anxiety and Sleep Problems in High-Functioning Autism Spectrum Disorder: Feasibility and Preliminary Findings, Stephen T. Foldes, Amanda R. Jensen, Austin Jacobson, Sarah Vassall, Emily Foldes, Ann Guthery, Danni Brown, Todd Levine, William James Tyler, and Richard E. Frye
Comparison of aspiration-first versus stentriever-first techniques in performing mechanical thrombectomy for large vessel occlusions, Vance L. Fredrickson, Phillip A. Bonney, Shivani D. Rangwala, Joshua S. Catapano, Tyler S. Cole, Daniel D. Cavalcanti, Neil Majmundar, D Andrew Wilkinson, Luis San Roman, Michael F. Waters, Felipe C. Albuquerque, and Andrew F. Ducruet
In reply: Is aspiration first-pass technique a better choice in mechanical thrombectomy for large vessel occlusions?, Vance L. Fredrickson and Andrew F. Ducruet
Comparative neuropathology in aging primates: A perspective, Carmen Freire-Cobo, Melissa K. Edler, Merina Varghese, Emily Munger, Jessie Laffey, Sophia Raia, Selena S. In, Bridget Wicinski, Maria Medalla, Sylvia E. Perez, Elliott J. Mufson, Joseph M. Erwin, Elaine E. Guevara, Chet C. Sherwood, Jennifer I. Luebke, Agnès Lacreuse, Mary A. Raghanti, and Patrick R. Hof
Implications of Oligomeric Amyloid-Beta (oAβ, Andrew A. George, Jaime M Vieira, Cameron Xavier-Jackson, Michael T Gee, John R Cirrito, Heather A Bimonte-Nelson, Marina R Picciotto, Ronald J. Lukas, and Paul Whiteaker
Targeting the gut to treat multiple sclerosis, Laura Ghezzi, Claudia Cantoni, Gabriela V. Pinget, Yanjiao Zhou, and Laura Piccio
α-synuclein aggregates induce c-Abl activation and dopaminergic neuronal loss by a feed-forward redox stress mechanism, Soumitra Ghosh, Seok Joon Won, Jiejie Wang, Rebecca Fong, Nicholas J.M. Butler, Arianna Moss, Candance Wong, June Pan, Jennifer Sanchez, Annie Huynh, Long Wu, Fredric P. Manfredsson, and Raymond A. Swanson
Impact of dual-headed pedicle screws on the biomechanics of lumbosacral junction multirod constructs, Jakub Godzik, Bernardo de Andrada Pereira, Anna G. Sawa, Jennifer N. Lehrman, Randall J. Hlubek, Brian P. Kelly, and Jay D. Turner
Biomechanics of open versus minimally invasive deformity correction: comparison of stability and rod strain between pedicle subtraction osteotomy and anterior column realignment, Jakub Godzik, Bernardo de Andrada Pereira, Anna G. Sawa, Jennifer N. Lehrman, Gregory M. Mundis, Randall J. Hlubek, Juan S. Uribe, Brian P. Kelly, and Jay D. Turner
TNPO2 variants associate with human developmental delays, neurologic deficits, and dysmorphic features and alter TNPO2 activity in Drosophila, Lindsey D. Goodman, Heidi Cope, Zelha Nil, Thomas A. Ravenscroft, Wu-Lin Charng, Shenzhao Lu, An-Chi Tien, Rolph Pfundt, David A. Koolen, Charlotte A. Haaxma, Hermine E. Veenstra-Knol, Jolien S. Wassink-Ruiter, Marijke R. Wevers, Melissa Jones, Laurence E. Walsh, Victoria H. Klee, Miel Theunis, Eric Legius, Dora Steel, Katy E. Barwick, Manju A. Kurian, Shekeeb S. Mohammad, Russell C. Dale, Paulien A. Terhal, Ellen van Binsbergen, Brian Kirmse, Bethany Robinette, Benjamin Cogné, Bertrand Isidor, Theresa A. Grebe, Peggy Kulch, and Bryan E. Hainline
Epigenetic inactivation of the autophagy–lysosomal system in appendix in Parkinson’s disease, Juozas Gordevicius, Peipei Li, Lee L. Marshall, Bryan A. Killinger, Sean Lang, Elizabeth Ensink, Nathan C. Kuhn, Wei Cui, Nazia Maroof, Roberta Lauria, Christina Rueb, Juliane Siebourg-Polster, Pierre Maliver, Jared Lamp, Irving Vega, Fredric P. Manfredsson, Markus Britschgi, and Viviane Labrie
Oxytocin receptors in the midbrain dorsal raphe are essential for postpartum maternal social and affective behaviors, Zachary A. Grieb, Emma G. Ford, Mahircan Yagan, Billy Y.B. Lau, Fredric P. Manfredsson, Keerthi Krishnan, and Joseph S. Lonstein
Novel experimental model of brain arteriovenous malformations using conditional Alk1 gene deletion in transgenic mice., Chul Han, Michael J Lang, Candice L Nguyen, Ernesto Luna Melendez, Shwetal Mehta, Gregory H Turner, Michael T Lawton, and S Paul Oh
Ascorbate-dependent and ascorbate-independent Mn porphyrin cytotoxicity: anticancer activity of Mn porphyrin-based SOD mimics through ascorbate-dependent and -independent routes, Bader Hasan, Artak Tovmasyan, Ines Batinic-Haberle, and Ludmil Benov
Uncertainty quantification in the radiogenomics modeling of EGFR amplification in glioblastoma, Leland S. Hu, Lujia Wang, Andrea Hawkins-Daarud, Jennifer M. Eschbacher, Kyle W. Singleton, Pamela R. Jackson, Kamala Clark-Swanson, Christopher P. Sereduk, Sen Peng, Panwen Wang, Junwen Wang, Leslie C. Baxter, Kris A. Smith, Gina L. Mazza, Ashley M. Stokes, Bernard R. Bendok, Richard S. Zimmerman, Chandan Krishna, Alyx B. Porter, Maciej M. Mrugala, Joseph M. Hoxworth, Teresa Wu, Nhan L. Tran, Kristin R. Swanson, and Jing Li
Emerging therapeutic targets for cerebral edema, Ruchira M. Jha, Sudhanshu P. Raikwar, Sandra Mihaljevic, Amanda M. Casabella, Joshua S. Catapano, Anupama Rani, Shashvat Desai, Volodymyr Gerzanich, and J Marc Simard
Sulfonylurea Receptor 1 in Central Nervous System Injury: An Updated Review, Ruchira M. Jha, Anupama Rani, Shashvat M. Desai, Sudhanshu Raikwar, Sandra Mihaljevic, Amanda Munoz-Casabella, Patrick M. Kochanek, Joshua Catapano, Ethan Winkler, Giuseppe Citerio, J Claude Hemphill, W Taylor Kimberly, Raj Narayan, Juan Sahuquillo, Kevin N. Sheth, and J Marc Simard
Association of Variants in the SPTLC1 Gene With Juvenile Amyotrophic Lateral Sclerosis, Janel O. Johnson, Ruth Chia, Danny E. Miller, Rachel Li, Ravindran Kumaran, Yevgeniya Abramzon, Nada Alahmady, Alan E. Renton, Simon D. Topp, J Raphael Gibbs, Mark R. Cookson, Marya S. Sabir, Clifton L. Dalgard, Claire Troakes, Ashley R. Jones, Aleksey Shatunov, Alfredo Iacoangeli, Ahmad Al Khleifat, Nicola Ticozzi, Vincenzo Silani, Cinzia Gellera, Ian P. Blair, Carol Dobson-Stone, John B. Kwok, Emily S. Bonkowski, Robin Palvadeau, Pentti J. Tienari, Karen E. Morrison, Pamela J. Shaw, Ammar Al-Chalabi, Robert H. Brown, and Andrea Calvo
Angiotensin II inhibition: a potential treatment to slow the progression of sarcopenia, Jeffrey Kingsley, Keiichi Torimoto, Tomoki Hashimoto, and Satoru Eguchi
Human papillomavirus vaccine guideline adherence among Arizona's Medicaid beneficiaries, Alexis Koskan, Lynne Klasko-Foster, Chad Stecher, Sue Rodriguez, Deborah Helitzer, and Wonsuk Yoo
Neurovascular networks in epilepsy: Correlating ictal blood perfusion with intracranial electrophysiology, Balu Krishnan, Simon Tousseyn, Chetan Sateesh Nayak, Thandar Aung, Ammar Kheder, Z Irene Wang, Guiyun Wu, Jorge Gonzalez-Martinez, Dileep Nair, Richard Burgess, Leonidas Iasemidis, Imad Najm, Juan Bulacio, and Andreas V. Alexopoulos
C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation, Deepti Lall, Ileana Lorenzini, Thomas A. Mota, Shaughn Bell, Thomas E. Mahan, Jason D. Ulrich, Hayk Davtyan, Jessica E. Rexach, A K. Muhammad, Oksana Shelest, Jesse Landeros, Michael Vazquez, Junwon Kim, Layla Ghaffari, Jacqueline Gire O'Rourke, Daniel H. Geschwind, Mathew Blurton-Jones, David M. Holtzman, Rita Sattler, and Robert H. Baloh
Genetic suppression of the dopamine D3 receptor in striatal D1 cells reduces the development of L-DOPA-induced dyskinesia, Kathryn Lanza, Ashley Centner, Michael Coyle, Isabella Del Priore, Fredric P. Manfredsson, and Christopher Bishop
TDP-43 proteinopathy alters the ribosome association of multiple mRNAs including the glypican Dally-like protein (Dlp)/GPC6, Erik M. Lehmkuhl, Suvithanandhini Loganathan, Eric Alsop, Alexander D. Blythe, Tina Kovalik, Nicholas P. Mortimore, Dianne Barrameda, Chuol Kueth, Randall J. Eck, Bhavani B. Siddegowda, Archi Joardar, Hannah Ball, Maria E. Macias, Robert Bowser, Kendall Van Keuren-Jensen, and Daniela C. Zarnescu
Dimensional Characterization of the Human Lumbar Interlaminar Space as a Guide for Safe Application of Minimally Invasive Dilators, Jennifer N. Lehrman, Celene B. Mulholland, Bernardo de Andrada Pereira, Anna G. Sawa, Brian P. Kelly, and Luis M. Tumialán
Tau aggregates are RNA-protein assemblies that mislocalize multiple nuclear speckle components, Evan Lester, Felicia K. Ooi, Nadine Bakkar, Jacob Ayers, Amanda L. Woerman, Joshua Wheeler, Robert Bowser, George A. Carlson, Stanley B. Prusiner, and Roy Parker
ActRIIB:ALK4-Fc alleviates muscle dysfunction and comorbidities in murine models of neuromuscular disorders, Jia Li, Maureen Fredericks, Marishka Cannell, Kathryn Wang, Dianne Sako, Michelle C. Maguire, Rosa Grenha, Katia Liharska, Lavanya Krishnan, Troy Bloom, Elitza P. Belcheva, Pedro A. Martinez, Roselyne Castonguay, Sarah Keates, Mark J. Alexander, Hyunwoo Choi, Asya V. Grinberg, R. Scott Pearsall, Paul Oh, Ravindra Kumar, and Rajasekhar N.V.S. Suragani
Telomeric alterations in the default mode network during the progression of Alzheimer’s disease: Selective vulnerability of the precuneus, Laura J. Mahady, Bin He, Michael Malek-Ahmadi, and Elliott J. Mufson
Reaccessing an occluded radial artery for neuroendovascular procedures: techniques and complication avoidance, Neil Majmundar, D Andrew Wilkinson, Joshua S. Catapano, Tyler S. Cole, Jacob F. Baranoski, Andrew F. Ducruet, and Felipe C. Albuquerque