The Barrow Neurological Institute is proud of its reputation as a medical research facility and is home to some of the most sophisticated research programs outside of an academic setting in the Southwestern United States. Researchers in the Barrow Neurosurgery Research Center are devoted to learning more about the causes of and treatments for a wide range of disorders, such as stroke, aneurysms, spinal cord injury, and hydrocephalus. Our research has led to treatments that are being used around the world. Within the Department are neurosurgeons who subspecialize in cerebrovascular and skull base, functional and stereotactic, pediatric, spine, tumor, and endovascular neurosurgery.
Physicians, scientists, and expert clinical staff come together with a commitment to developing new techniques for the prevention, diagnosis, treatment, and rehabilitation of neurological illnesses and injuries. The leadership of internationally respected physicians keeps Barrow at the forefront of neuroscience. The compassionate expertise of its extensive staff of nurses, technologists, therapists and support personnel is evident in every aspect of care provided.
Our mission is to advance the knowledge and practice of medicine in neuroscience through basic and clinical research, education of medical professionals, and innovation in clinical techniques and technology.
Submissions from 2021
TDP-43 proteinopathy alters the ribosome association of multiple mRNAs including the glypican Dally-like protein (Dlp)/GPC6, Erik M. Lehmkuhl, Suvithanandhini Loganathan, Eric Alsop, Alexander D. Blythe, Tina Kovalik, Nicholas P. Mortimore, Dianne Barrameda, Chuol Kueth, Randall J. Eck, Bhavani B. Siddegowda, Archi Joardar, Hannah Ball, Maria E. Macias, Robert Bowser, Kendall Van Keuren-Jensen, and Daniela C. Zarnescu
Dimensional Characterization of the Human Lumbar Interlaminar Space as a Guide for Safe Application of Minimally Invasive Dilators, Jennifer N. Lehrman, Celene B. Mulholland, Bernardo de Andrada Pereira, Anna G. Sawa, Brian P. Kelly, and Luis M. Tumialán
Tau aggregates are RNA-protein assemblies that mislocalize multiple nuclear speckle components, Evan Lester, Felicia K. Ooi, Nadine Bakkar, Jacob Ayers, Amanda L. Woerman, Joshua Wheeler, Robert Bowser, George A. Carlson, Stanley B. Prusiner, and Roy Parker
ActRIIB:ALK4-Fc alleviates muscle dysfunction and comorbidities in murine models of neuromuscular disorders, Jia Li, Maureen Fredericks, Marishka Cannell, Kathryn Wang, Dianne Sako, Michelle C. Maguire, Rosa Grenha, Katia Liharska, Lavanya Krishnan, Troy Bloom, Elitza P. Belcheva, Pedro A. Martinez, Roselyne Castonguay, Sarah Keates, Mark J. Alexander, Hyunwoo Choi, Asya V. Grinberg, R. Scott Pearsall, Paul Oh, Ravindra Kumar, and Rajasekhar N.V.S. Suragani
Telomeric alterations in the default mode network during the progression of Alzheimer’s disease: Selective vulnerability of the precuneus, Laura J. Mahady, Bin He, Michael Malek-Ahmadi, and Elliott J. Mufson
Reaccessing an occluded radial artery for neuroendovascular procedures: techniques and complication avoidance, Neil Majmundar, D Andrew Wilkinson, Joshua S. Catapano, Tyler S. Cole, Jacob F. Baranoski, Andrew F. Ducruet, and Felipe C. Albuquerque
Generation of two induced pluripotent stem cell (iPSC) lines from an ALS patient with simultaneous mutations in KIF5A and MATR3 genes, David X. Medina, Ashley Boehringer, Marissa Dominick, Ileana Lorenzini, Sara Saez-Atienzar, Erik P. Pioro, Rita Sattler, Bryan Traynor, and Robert Bowser
The BDNF Val66Met polymorphism (rs6265) enhances dopamine neuron graft efficacy and side-effect liability in rs6265 knock-in rats, Natosha M. Mercado, Jennifer A. Stancati, Caryl E. Sortwell, Rebecca L. Mueller, Samuel A. Boezwinkle, Megan F. Duffy, D Luke Fischer, Ivette M. Sandoval, Fredric P. Manfredsson, Timothy J. Collier, and Kathy Steece-Collier
Cerebellar Calcium-Binding Protein and Neurotrophin Receptor Defects in Down Syndrome and Alzheimer's Disease, Jennifer C. Miguel, Sylvia E. Perez, Michael Malek-Ahmadi, and Elliott J. Mufson
Pathophysiology of the choroid plexus in brain diseases, Sandra Mihaljevic, Alena Michalicova, Mangesh Bhide, and Andrej Kovac
Tocilizumab is safe and tolerable and reduces C-reactive protein concentrations in the plasma and cerebrospinal fluid of ALS patients, Carol Milligan, Nazem Atassi, Suma Babu, Richard J. Barohn, James B. Caress, Merit E. Cudkowicz, Armineuza Evora, Gregory A. Hawkins, Marlena Wosiski-Kuhn, Eric A. Macklin, Jeremy M. Shefner, Zachary Simmons, Robert P. Bowser, and Shafeeq S. Ladha
Postnatal Cytoarchitecture and Neurochemical Hippocampal Dysfunction in Down Syndrome, David G. Moreno, Emma C. Utagawa, Nicoleta C. Arva, Kristian T. Schafernak, Elliott J. Mufson, and Sylvia E. Perez
Editorial: Down Syndrome, Neurodegeneration and Dementia, Elliott J. Mufson, Stephen D. Ginsberg, Tao Ma, Aurélie Ledreux, and Sylvia E. Perez
Chronic traumatic encephalopathy and the nucleus basalis of Meynert., Elliott J Mufson, Christy Kelley, and Sylvia E Perez
Chronic traumatic encephalopathy and the nucleus basalis of Meynert, Elliott J. Mufson, Christy Kelley, and Sylvia E. Perez
Biomechanics of Circumferential Cervical Fixation Using Posterior Facet Cages: A Cadaveric Study, Bernardo de Pereira, Joshua E. Heller, Jennifer N. Lehrman, Anna G. Sawa, and Brian P. Kelly
Maternal Choline Supplementation as a Potential Therapy for Down Syndrome: Assessment of Effects Throughout the Lifespan, Brian E. Powers, Ramon Velazquez, Myla S. Strawderman, Stephen D. Ginsberg, Elliott J. Mufson, and Barbara J. Strupp
Evaluation of amyotrophic lateral sclerosis-induced muscle degeneration using magnetic resonance-based relaxivity contrast imaging (RCI), Sudarshan Ragunathan, Laura C. Bell, Natenael Semmineh, Ashley M. Stokes, Jeremy M. Shefner, Robert Bowser, Shafeeq Ladha, and C. Chad Quarles
Targeting chromatin dysregulation in organ fibrosis, Anupama Rani, Chiahsuan Chin, Ross Bremner, Thalachallour Mohanakumar, and Sureshbabu Angara
ALSUntangled 55: vitamin E (α-tocopherol), Bedlack Richard, Jesse Crayle, Carmel Armon, Paul Barkhaus, Benjamin Barnes, Michael Benatar, Tulio Bertorini, Robert Bowser, Mark Bromberg, Benjamin Brooks, Lev Brylev, James Caress, Greg Carter, Merit Cudkowicz, Jon Glass, Volkan Granit, Michael Graves, Terri Heiman-Patterson, Leann Jiang, Christopher McDermott, Gary Pattee, Erik Pioro, Michael Rivner, Jeffrey Rothstein, Kristiana Salmon, Kim Staats, and Paul Wicks
To Zoom or Not to Zoom: The Should I Travel Index Revisited during the Coronavirus Disease Pandemic, Seward B. Rutkove, Jeremy M. Shefner, Robert Bowser, Martin R. Turner, and Michael Benatar
Gene Therapy to Modulate Alpha-Synuclein in Synucleinopathies, Ivette M. Sandoval, David J. Marmion, Kimberly T. Meyers, and Fredric P. Manfredsson
In Vitro Biomechanics of Human Cadaveric Cervical Spines With Mature Fusion, Anna G. Sawa, Bernardo de Andrada Pereira, Nestor G. Rodriguez-Martinez, Phillip M. Reyes, Brian P. Kelly, and Neil R. Crawford
Alterations of the gut mycobiome in patients with MS, Saumya Shah, Alberto Locca, Yair Dorsett, Claudia Cantoni, Laura Ghezzi, Qingqi Lin, Suresh Bokoliya, Hunter Panier, Cassandra Suther, Matthew Gormley, Yue Liu, Emily Evans, Robert Mikesell, Kathleen Obert, Amber Salter, Anne H. Cross, Phillip I. Tarr, Amy Lovett-Racke, Laura Piccio, and Yanjiao Zhou
Investigating the relationship between multi-scale perfusion and white matter microstructural integrity in patients with relapsing-remitting MS, Nicholas J. Sisco, Aimee Borazanci, Richard Dortch, and Ashley M. Stokes
Orexin (hypocretin) mediates light-dependent fluctuation of hippocampal function in a diurnal rodent, Joel E. Soler, Hang Xiong, Faiez Samad, Fredric P. Manfredsson, Alfred J. Robison, Antonio A. Núñez, and Lily Yan
Evaluation of single bolus, dual-echo dynamic susceptibility contrast MRI protocols in brain tumor patients, Ashley M. Stokes, Maurizio Bergamino, Lea Alhilali, Leland S. Hu, John P. Karis, Leslie C. Baxter, Laura C. Bell, and C. Chad Quarles
Development of a spiral spin- and gradient-echo (spiral-SAGE) approach for improved multi-parametric dynamic contrast neuroimaging, Ashley M. Stokes, Sudarshan Ragunathan, Ryan K. Robison, Alberto Fuentes, Laura C. Bell, John P. Karis, James G. Pipe, and C. Chad Quarles
High cerebrospinal amyloid-β 42 is associated with normal cognition in individuals with brain amyloidosis, Andrea Sturchio, Alok K. Dwivedi, Christina B. Young, Tarja Malm, Luca Marsili, Jennifer S. Sharma, Abhimanyu Mahajan, Emily J. Hill, Samir El Andaloussi, Kathleen L. Poston, Fredric P. Manfredsson, Lon S. Schneider, Kariem Ezzat, and Alberto J. Espay
Advancing mechanistic understanding and biomarker development in amyotrophic lateral sclerosis, Alexander G. Thompson, Patrick Oeckl, Emily Feneberg, Robert Bowser, Markus Otto, Roman Fischer, Benedikt Kessler, and Martin R. Turner
Gene expression profiling of brain endothelial cells after experimental subarachnoid haemorrhage, Michael K. Tso, Paul Turgeon, Bert Bosche, Charles K. Lee, Tian Nie, Josephine D’Abbondanza, Jinglu Ai, Philip A. Marsden, and R. Loch Macdonald
Defining the Caprin-1 Interactome in Unstressed and Stressed Conditions, Lucas Vu, Asmita Ghosh, Chelsea Tran, Walters Aji Tebung, Hadjara Sidibé, Krystine Garcia-Mansfield, Victoria David-Dirgo, Ritin Sharma, Patrick Pirrotte, Robert Bowser, and Christine Vande Velde
Adjacent-segment effects of lumbar cortical screw-rod fixation versus pedicle screw-rod fixation with and without interbody support, Piyanat Wangsawatwong, Anna G. Sawa, Bernardo de Andrada Pereira, Jennifer N. Lehrman, Luke K. O'Neill, Jay D. Turner, Juan S. Uribe, and Brian P. Kelly
Does the Choice of Spinal Interbody Fusion Approach Significantly Affect Adjacent Segment Mobility?, Piyanat Wangsawatwong, Anna G. Sawa, Bernardo de Pereira, Jennifer N. Lehrman, Jay D. Turner, Juan S. Uribe, and Brian P. Kelly
Role of perivascular and meningeal macrophages in outcome following experimental subarachnoid hemorrhage, Hoyee Wan, Shakira Brathwaite, Jinglu Ai, Kullervo Hynynen, and R. Loch Macdonald
Blood-spinal cord barrier leakage is independent of motor neuron pathology in ALS, Sarah Waters, Molly E. Swanson, Birger V. Dieriks, Yibin B. Zhang, Natasha L. Grimsey, Helen C. Murray, Clinton Turner, Henry J. Waldvogel, Richard L. Faull, Jiyan An, Robert Bowser, Maurice A. Curtis, Mike Dragunow, and Emma Scotter
Electrophysiologic Mapping for Target Acquisition in Deep Brain Stimulation May Become Unnecessary in the Era of Intraoperative Imaging, Baltazar Zavala, Zaman Mirzadeh, Tsinsue Chen, Margaret Lambert, Kristina M. Chapple, Rohit Dhall, and Francisco A. Ponce
T, J Zhu, N Hu, J Hou, X Liang, Y Wang, H Zhang, P Wang, T Chen, W Chen, and L Wang
Submissions from 2020
C3a receptor antagonist therapy is protective with or without thrombolysis in murine thromboembolic stroke., Saif Ahmad, Chirayu Pandya, Adam Kindelin, Kanchan Bhatia, Rafay Chaudhary, Alok Kumar Dwivedi, Jennifer M Eschbacher, Qiang Liu, Michael F Waters, Md Nasrul Hoda, and Andrew F. Ducruet
Impact of COVID-19 on the cerebrovascular system and the prevention of RBC lysis., N Akhter, S Ahmad, F A Alzahrani, S A Dar, M Wahid, S Haque, K Bhatia, S Sr Almalki, R A Alharbi, and A A A Sindi
Letter: An International Investigation Into the COVID-19 Pandemic and Workforce Depletion in Highly Specialized Neurointerventional Units - Insights From Stroke Thrombectomy and Aneurysm Registry and Endovascular Neurosurgery Research Group, Ali Alawieh, Sami Al Kasab, Eyad Almallouhi, Michael R. Levitt, Pascal M. Jabbour, Ahmad Sweid, Robert M. Starke, Vasu Saini, Kyle M. Fargen, Stacey Q. Wolfe, Adam S. Arthur, Nitin Goyal, Isabel Fragata, Ilko Maier, Charles Matouk, Brian M. Howard, Jonathan A. Grossberg, Michael Cawley, Peter Kan, Muhammad Hafeez, Justin Singer, R Webster Crowley, Krishna C. Joshi, Waleed Brinjikji, Luis E. Savastano, Christopher S. Ogilvy, Santiago Gomez-Paz, Elad Levy, Muhammad Waqas, Maxim Mokin, Erol Veznedaroglu, and Mandy Binning
International experience of mechanical thrombectomy during the COVID-19 pandemic: insights from STAR and ENRG, Sami Al Kasab, Eyad Almallouhi, Ali Alawieh, Michael R. Levitt, Pascal Jabbour, Ahmad Sweid, Robert M. Starke, Vasu Saini, Stacey Q. Wolfe, Kyle M. Fargen, Adam S. Arthur, Nitin Goyal, Abhi Pandhi, Isabel Fragata, Ilko Maier, Charles Matouk, Jonathan A. Grossberg, Brian M. Howard, Peter Kan, Muhammad Hafeez, Clemens M. Schirmer, R Webster Crowley, Krishna C. Joshi, Stavropoula I. Tjoumakaris, Shakeel Chowdry, William Ares, Christopher Ogilvy, Santiago Gomez-Paz, Ansaar T. Rai, Maxim Mokin, Waldo Guerrero, and Min S. Park
Hypothalamic perineuronal net assembly is required for sustained diabetes remission induced by fibroblast growth factor 1 in rats, Kimberly M. Alonge, Zaman Mirzadeh, Jarrad M. Scarlett, Aric F. Logsdon, Jenny M. Brown, Elaine Cabrales, Christina K. Chan, Karl J. Kaiyala, Marie A. Bentsen, William A. Banks, Miklos Guttman, Thomas N. Wight, Gregory J. Morton, and Michael W. Schwartz
Quantitative Electroencephalography After Pediatric Anterior Circulation Stroke, Brian L. Appavu, M'hamed H. Temkit, Stephen T. Foldes, Brian T. Burrows, Austin M. Jacobson, Tara K. Mangum, Varina L. Boerwinkle, Iris Marku, Todd A. Abruzzo, and Phillip D. Adelson
Selective inversion recovery quantitative magnetization transfer imaging: Toward a 3 T clinical application in multiple sclerosis., Francesca Bagnato, Giulia Franco, Fei Ye, Run Fan, Patricia Commiskey, Seth A Smith, Junzhong Xu, and Richard Dortch
The role of hnRNPs in frontotemporal dementia and amyotrophic lateral sclerosis, Alexander Bampton, Lauren M. Gittings, Pietro Fratta, Tammaryn Lashley, and Ariana Gatt
ALSUntangled 56: “ten red flags”-things to be wary of in alternative or off-label products, Richard Bedlack, Carmel Armon, Paul Barkhaus, Benjamin Barnes, Michael Benatar, Michael Bereman, Robert Bowser, Mark Bromberg, Lev Brylev, James Caress, Greg Carter, Amy Chen, Nick Cole, Jesse Crayle, Merit Cudkocwicz, Eva Feldman, Americo Fernandes, Stephen Goutman, Volkan Granit, Lawrence Hayward, Carlayne Jackson, Leanne Jiang, Pamela Kittrell, Stephen Kolb, Nicholas Maragakis, Christopher McDermott, Kathy Mitchell, Natasha Olby, Lyle Ostrow, Sabrina Paganoni, and Gary Pattee
Analysis of postprocessing steps for residue function dependent dynamic susceptibility contrast (DSC)-MRI biomarkers and their clinical impact on glioma grading for both 1.5 and 3T., Laura C Bell, A. Stokes, and C. Quarles
Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission, Marie A. Bentsen, Dylan M. Rausch, Zaman Mirzadeh, Kenjiro Muta, Jarrad M. Scarlett, Jenny M. Brown, Vicente Herranz-Pérez, Arian F. Baquero, Jonatan Thompson, Kimberly M. Alonge, Chelsea L. Faber, Karl J. Kaiyala, Camdin Bennett, Charles Pyke, Cecilia Ratner, Kristoffer L. Egerod, Birgitte Holst, Thomas H. Meek, Burak Kutlu, Yu Zhang, Thomas Sparso, Kevin L. Grove, Gregory J. Morton, Birgitte R. Kornum, José-Manuel García-Verdugo, Anna Secher, Rasmus Jorgensen, Michael W. Schwartz, and Tune H. Pers
Assessing White Matter Pathology in Early-Stage Parkinson Disease Using Diffusion MRI: A Systematic Review, Maurizio Bergamino, Elizabeth G. Keeling, Virendra R. Mishra, Ashley M. Stokes, and Ryan R. Walsh
Radicava / edaravone findings in biomarkers from ALS (REFINE ALS): Protocol and study design, James Berry, Benjamin Brooks, Angela Genge, Terry Heiman-Patterson, Stanley Appel, Michael Benatar, Robert Bowser, Merit Cudkowicz, Clifton Gooch, Jeremy Shefner, Jurjen Westra, Wendy Agnese, Charlotte Merrill, Sally Nelson, and Stephen Apple
Resting-state functional MRI connectivity impact on epilepsy surgery plan and surgical candidacy: prospective clinical work, Varina L. Boerwinkle, Lucia Mirea, William D. Gaillard, Bethany L. Sussman, Diana Larocque, Alexandra Bonnell, Jennifer S. Ronecker, Matthew M. Troester, John F. Kerrigan, Stephen T. Foldes, Brian Appavu, Randa Jarrar, Korwyn Williams, Angus A. Wilfong, and P David Adelson
Range of Motion Testing of a Novel 3D-Printed Synthetic Spine Model., Michael A Bohl, Sarah McBryan, Anna G U S Newcomb, Jennifer N Lehrman, Brian P. Kelly, Peter Nakaji, Steve W Chang, Juan S. Uribe, Jay D Turner, and U Kumar Kakarla
Innovative Long-Dose Neurorehabilitation for Balance and Mobility in Chronic Stroke: A Preliminary Case Series, Catherine Boissoneault, Tyler Grimes, Dorian K. Rose, Michael F. Waters, Anna Khanna, Somnath Datta, and Janis J. Daly
ALSUntangled 51: RCH4., Robert Bowser and ALSUntangled Group
ALSUntangled 53: Carnitine supplements., Robert Bowser and ALSUntangled Group
ALSUntangled 58: Azathioprine., Robert Bowser and ALSUntangled Group
ALSUntangled No. 52: Glutathione., Robert Bowser and ALSUntangled Group
ALSUntangled No. 54: "LEAP2BFIT"., Robert Bowser and ALSUntangled Group
Multicenter postmarket analysis of the neuroform atlas stent for stent-assisted coil embolization of intracranial aneurysms, J. K. Burkhardt, V. Srinivasan, A. Srivatsan, F. Albuquerque, A. F. Ducruet, B. Hendricks, B. A. Gross, B. T. Jankowitz, A. J. Thomas, C. S. Ogilvy, G. A. Maragkos, A. Enriquez-Marulanda, R. W. Crowley, M. R. Levitt, L. J. Kim, C. J. Griessenauer, C. M. Schirmer, S. Dalal, K. Piper, M. Mokin, E. A. Winkler, A. A. Abla, C. McDougall, L. Birnbaum, J. Mascitelli, M. Litao, O. Tanweer, H. Riina, J. Johnson, S. Chen, and P. Kan
Tissue sodium content in patients with systemic lupus erythematosus: association with disease activity and markers of inflammation., D A Carranza-León, A Oeser, A Marton, P Wang, J C Gore, J Titze, C M Stein, C P Chung, and M J Ormseth
Middle Meningeal Artery Embolization for Chronic Subdural Hematoma, Joshua S. Catapano, Candice L. Nguyen, Andre A. Wakim, Felipe C. Albuquerque, and Andrew F. Ducruet
Acute modulation of the limbic network with low and high-frequency stimulation of the human fornix, Ganne Chaitanya, Emilia Toth, Diana Pizarro, Leonidas Iasemidis, Teresa A. Murray, Kristen Riley, and Sandipan Pati
Phosphodiesterase 9A Inhibition Facilitates Corticostriatal Transmission in Wild-Type and Transgenic Rats That Model Huntington's Disease, Shreaya Chakroborty, Fredric P. Manfredsson, Alexander M. Dec, Peter W. Campbell, Grace E. Stutzmann, Vahri Beaumont, and Anthony R. West
Time-delimited signaling of MET receptor tyrosine kinase regulates cortical circuit development and critical period plasticity., Ke Chen, Xiaokuang Ma, Antoine Nehme, Jing Wei, Yan Cui, Yuehua Cui, Dezhong Yao, Jie Wu, Trent Anderson, Deveroux Ferguson, Pat Levitt, and Shenfeng Qiu
Long-term post-mortem studies following neurturin gene therapy in patients with advanced Parkinson's disease, Yaping Chu, Raymond T. Bartus, Fredric P. Manfredsson, C. Warren Olanow, and Jeffrey H. Kordower
TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis, Francesca Cignarella, Fabia Filipello, Bryan Bollman, Claudia Cantoni, Alberto Locca, Robert Mikesell, Melissa Manis, Adiljan Ibrahim, Li Deng, Bruno A. Benitez, Carlos Cruchaga, Danilo Licastro, Kathie Mihindukulasuriya, Oscar Harari, Michael Buckland, David M. Holtzman, Arnon Rosenthal, Tina Schwabe, Ilaria Tassi, and Laura Piccio
RBM45 associates with nuclear stress bodies and forms nuclear inclusions during chronic cellular stress and in neurodegenerative diseases, Mahlon Collins, Yang Li, and Robert Bowser
Rapid whole-brain quantitative magnetization transfer imaging using 3D selective inversion recovery sequences., Matthew J Cronin, Junzhong Xu, Francesca Bagnato, Daniel F Gochberg, John C Gore, and Richard Dortch
A comparison of AAV-vector production methods for gene therapy and preclinical assessment, Marcus Davidsson, Matilde Negrini, Swantje Hauser, Alexander Svanbergsson, Marcus Lockowandt, Giuseppe Tomasello, Fredric P. Manfredsson, and Andreas Heuer
Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis., Ramita Dewan, Ruth Chia, Jinhui Ding, Richard A Hickman, Thor D Stein, Yevgeniya Abramzon, Sarah Ahmed, Marya S Sabir, Makayla K Portley, Arianna Tucci, Kristina Ibáñez, F N U Shankaracharya, Pamela Keagle, Giacomina Rossi, Paola Caroppo, Fabrizio Tagliavini, Maria L Waldo, Per M Johansson, Christer F Nilsson, James B Rowe, Luisa Benussi, Giuliano Binetti, Roberta Ghidoni, Edwin Jabbari, Coralie Viollet, Jonathan D Glass, Andrew B Singleton, Vincenzo Silani, Owen A Ross, Mina Ryten, Ali Torkamani, Toshiko Tanaka, Luigi Ferrucci, Susan M Resnick, Stuart Pickering-Brown, Christopher B Brady, Neil Kowal, John A Hardy, Vivianna Van Deerlin, Jean Paul Vonsattel, Matthew B Harms, Huw R Morris, Raffaele Ferrari, John E Landers, Adriano Chiò, J Raphael Gibbs, Clifton L Dalgard, Sonja W Scholz, Bryan J Traynor, and Robert Bowser
Neuron loss associated with age but not Alzheimer's disease pathology in the chimpanzee brain: Aging in chimpanzee brain, Melissa K. Edler, Emily L. Munger, Richard S. Meindl, William D. Hopkins, John J. Ely, Joseph M. Erwin, Elliott J. Mufson, Patrick R. Hof, Chet C. Sherwood, and Mary Ann Raghanti
Single-cell RNA-seq analysis of human CSF microglia and myeloid cells in neuroinflammation, Ekaterina Esaulova, Claudia Cantoni, Irina Shchukina, Konstantin Zaitsev, Robert C. Bucelli, Gregory F. Wu, Maxim N. Artyomov, Anne H. Cross, and Brian T. Edelson
Diffusion Tensor Tractrography Visualizes Partial Nerve Laceration Severity as Early as 1 Week After Surgical Repair in a Rat Model Ex Vivo., Angel F Farinas, Isaac V Manzanera Esteve, Alonda C Pollins, Nancy L Cardwell, Mark D Does, Richard Dortch, and Wesley P Thayer
Effects of MEG-based neurofeedback for hand rehabilitation after tetraplegia: preliminary findings in cortical modulations and grip strength, Stephen T. Foldes, Michael L. Boninger, Douglas J. Weber, and Jennifer L. Collinger
Shift in electrocorticography electrode locations after surgical implantation in children, Stephen T. Foldes, Bryce T. Munter, Brian L. Appavu, John F. Kerrigan, and P David Adelson
Mast Cell Promotes the Development of Intracranial Aneurysm Rupture, Hajime Furukawa, Kosuke Wada, Yoshiteru Tada, Atsushi Kuwabara, Hiroki Sato, Jinglu Ai, Michael T. Lawton, and Tomoki Hashimoto
Dual Effect of 5-HT, Ming Gao, Taleen S Der-Ghazarian, Shuangtao Li, Shenfeng Qiu, Janet L Neisewander, and Jie Wu
T cells producing GM-CSF and IL-13 are enriched in the cerebrospinal fluid of relapsing MS patients, Laura Ghezzi, Claudia Cantoni, Francesca Cignarella, Bryan Bollman, Anne H. Cross, Amber Salter, Daniela Galimberti, Marina Cella, and Laura Piccio
Symmetric dimethylation of poly-GR correlates with disease duration in C9orf72 FTLD and ALS and reduces poly-GR phase separation and toxicity, Lauren M. Gittings, Steven Boeynaems, Daniel Lightwood, Alison Clargo, Sarfaraj Topia, Lisa Nakayama, Claire Troakes, David M. Mann, Aaron D. Gitler, Tammaryn Lashley, and Adrian M. Isaacs
Recent advances in understanding amyotrophic lateral sclerosis and emerging therapies, Lauren M. Gittings and Rita Sattler
Optimizing biomechanics of anterior column realignment for minimally invasive deformity correction., Jakub Godzik, Bernardo de Andrada Pereira, Anna G U S Newcomb, Jennifer N Lehrman, Gregory M Mundis, Randall J Hlubek, Juan S. Uribe, Brian P. Kelly, and Jay D Turner
A multi-center study of neurofilament assay reliability and inter-laboratory variability, Elizabeth Gray, Patrick Oeckl, Maria D.M. Amador, Ulf Andreasson, Jiyan An, Kaj Blennow, Robert Bowser, Maxim De Schaepdryver, Amanda Heslegrave, Jens Kuhle, Aleksandra Maceski, Marleen Koel-Simmelink, Foudil Lamari, Vittoria Lombardi, Andrea Malaspina, Irina Nilsson, Koen Poesen, François Salachas, Petra Steinacker, Charlotte E. Teunissen, Philip Van Damme, Henrik Zetterberg, Albert Ludolph, Andreas Jeromin, Martin R. Turner, and Markus Otto
Expression profiling of precuneus layer III cathepsin D-immunopositive pyramidal neurons in mild cognitive impairment and Alzheimer's disease: Evidence for neuronal signaling vulnerability., Bin He, Sylvia E Perez, Sang H Lee, Stephen D Ginsberg, Michael Malek-Ahmadi, and Elliott J. Mufson
Performance of standardized relative CBV for quantifying regional histologic tumor burden in recurrent high-grade glioma: Comparison against normalized relative CBV using image-localized stereotactic biopsies, J. M. Hoxworth, J. M. Eschbacher, A. C. Gonzales, K. W. Singleton, G. D. Leon, K. A. Smith, A. M. Stokes, Y. Zhou, G. L. Mazza, A. B. Porter, M. M. Mrugala, R. S. Zimmerman, B. R. Bendok, D. P. Patra, C. Krishna, J. L. Boxerman, L. C. Baxter, K. R. Swanson, C. C. Quarles, K. M. Schmainda, and L. S. Hu
Longitudinal biomarkers in amyotrophic lateral sclerosis, Fen Huang, Yuda Zhu, Jennifer Hsiao-Nakamoto, Xinyan Tang, Jason C. Dugas, Miriam Moscovitch-Lopatin, Jonathan D. Glass, Robert H. Brown, Shafeeq S. Ladha, David Lacomis, Jeffrey M. Harris, Kimberly Scearce-Levie, Carole Ho, Robert Bowser, and James D. Berry
Smartphone-based meditation for myeloproliferative neoplasm patients: Feasibility study to inform future trials, Jennifer Huberty, Ryan Eckert, Linda Larkey, Jonathan Kurka, Sue A.Rodriguez De Jesus, Wonsuk Yoo, and Ruben Mesa
Directed Connectivity Analysis of the Neuro-Cardio- and Respiratory Systems Reveals Novel Biomarkers of Susceptibility to SUDEP, T Noah Hutson, Farnaz Rezaei, Nicole M. Gautier, Jagadeeswaran Indumathy, Edward Glasscock, and Leonidas Iasemidis
Neurothrombectomy for Acute Ischemic Stroke Across Clinical Trial Design and Technique: A Single Center Pooled Analysis, Tudor G. Jovin, Shashvat M. Desai, Amin Aghaebrahim, Andrew F. Ducruet, Dan-Victor Giurgiutiu, Bradley A. Gross, Maxim Hammer, Brian T. Jankowitz, Mouhammad A. Jumaa, Cynthia Kenmuir, Guillermo Linares, Vivek Reddy, Marcelo Rocha, Matthew Starr, Viktoria Totoraitis, Lawrence Wechsler, Syed Zaidi, and Ashutosh P. Jadhav
Norepinephrine metabolite DOPEGAL activates AEP and pathological Tau aggregation in locus coeruleus., Seong Su Kang, Xia Liu, Eun Hee Ahn, Jie Xiang, Fredric P Manfredsson, Xifei Yang, Hongbo R Luo, L Cameron Liles, David Weinshenker, and Keqiang Ye
ZPR1 prevents R-loop accumulation, upregulates SMN2 expression and rescues spinal muscular atrophy, Annapoorna Kannan, Xiaoting Jiang, Lan He, Saif Ahmad, and Laxman Gangwani
Morphological Changes in Astrocytes by Self-Oxidation of Dopamine to Polydopamine and Quantification of Dopamine through Multivariate Regression Analysis of Polydopamine Images, Anik Karan, Elnaz Khezerlou, Farnaz Rezaei, Leon Iasemidis, and Mark A. DeCoster
Overexpression of activin receptor-like kinase 1 in endothelial cells suppresses development of arteriovenous malformations in mouse models of hereditary hemorrhagic telangiectasia, Yong Hwan Kim, Phuong Nhung Vu, Se Woon Choe, Chang Jin Jeon, Helen M. Arthur, Calvin P.H. Vary, Young Jae Lee, and S. Paul Oh
Evaluation of abnormal styloid anatomy as a cause of internal jugular vein compression using a 3D-printed model: a laboratory investigation., Jennifer N Lehrman, Mohan Narayanan, Claudio Cavallo, Anna G U S Newcomb, Xiaochun Zhao, Brian P. Kelly, Neil R Crawford, and Peter Nakaji
Regional binding of tau and amyloid PET tracers in Down syndrome autopsy brain tissue, L. Lemoine, A. Ledreux, E. J. Mufson, S. E. Perez, G. Simic, E. Doran, I. Lott, S. Carroll, K. Bharani, S. Thomas, A. Gilmore, E. D. Hamlett, A. Nordberg, and A. C. Granholm
Fe Porphyrin-Based SOD Mimic and Redox-Active Compound, (OH)FeTnHex-2-PyP, in a Rodent Ischemic Stroke (MCAO) Model: Efficacy and Pharmacokinetics as Compared to Its Mn Analogue, (HO)MnTnHex-2-PyP, Litao Li, Artak Tovmasyan, Huaxin Sheng, Bin Xu, Romulo S. Sampaio, Julio S. Reboucas, David S. Warner, Ines Batinic-Haberle, and Ivan Spasojevic
Braak Stage, Cerebral Amyloid Angiopathy, and Cognitive Decline in Early Alzheimer's Disease., Michael Malek-Ahmadi, Sylvia E Perez, Kewei Chen, and Elliott J. Mufson
The Future of GDNF in Parkinson's Disease, Fredric P. Manfredsson, Nicole K. Polinski, Thyagarajan Subramanian, Nicholas Boulis, Dustin R. Wakeman, and Ronald J. Mandel
Cocaine potently blocks neuronal α, Ze-Gang Ma, Nan Jiang, Yuan-Bing Huang, Xiao-Kuang Ma, Jason Brek Eaton, Ming Gao, Yong-Chang Chang, Ronald J. Lukas, Paul Whiteaker, Janet Neisewander, and Jie Wu
Intravenously Administered, Retinoid Activating Nanoparticles Increase Lifespan and Reduce Neurodegeneration in the SOD1, David X. Medina, Eugene P Chung, Collin D Teague, Robert Bowser, and Rachael W Sirianni