Takayasu's arteritis: Is it a reversible disease? Case Report and Literature Review

Authors

Vishnumurthy Shushrutha Hedna, Department of Neurology, University of Florida, Archer Road, Gainesville, Florida, 32611, USA.
Akhil Patel
Sharathchandra Bidari
Melissa Elder
Brian L. Hoh
Anthony Yachnis
Michael F. Waters

Document Type

Article

Abstract

BACKGROUND: Takayasu's arteritis (TA) is a rare and potentially devastating condition leading to prolonged morbidity and even death. CASE DESCRIPTION: We report an 18-year-old female presenting with an acute ischemic stroke treated with intravenous thrombolysis and subsequent endovascular therapy (ET) with excellent results followed by chronic treatment with immunosuppressants after a formal diagnosis of TA. Following immunosupression, improvement was noted in critical stenoses of the extracranial large vessels. CONCLUSION: These observations underscore the importance of early initiation of therapy to halt or even reverse vascular pathology, though frequent follow up is mandatory as relapse is common. In this article we provide brief review of the current literature on TA related to pathophysiology, criterion for diagnosis, therapy, and follow up.

Keywords

Acute stroke, Takayasu's arteritis, endovascular treatment, reversibility, stenosis

Publication Date

1-1-2012

Publication Title

Surgical neurology international

E-ISSN

2152-7806

Volume

3

First Page

132

PubMed ID

23227437

Digital Object Identifier (DOI)

10.4103/2152-7806.102947

Recommended Citation

Hedna, Vishnumurthy Shushrutha; Patel, Akhil; Bidari, Sharathchandra; Elder, Melissa; Hoh, Brian L.; Yachnis, Anthony; and Waters, Michael F., "Takayasu's arteritis: Is it a reversible disease? Case Report and Literature Review" (2012). Translational Neuroscience. 1345.
https://scholar.barrowneuro.org/neurobiology/1345