The Barrow Neurological Institute is proud of its reputation as a medical research facility and is home to some of the most sophisticated research programs outside of an academic setting in the Southwestern United States. Researchers in the Barrow Neurosurgery Research Center are devoted to learning more about the causes of and treatments for a wide range of disorders, such as stroke, aneurysms, spinal cord injury, and hydrocephalus. Our research has led to treatments that are being used around the world. Within the Department are neurosurgeons who subspecialize in cerebrovascular and skull base, functional and stereotactic, pediatric, spine, tumor, and endovascular neurosurgery.

Physicians, scientists, and expert clinical staff come together with a commitment to developing new techniques for the prevention, diagnosis, treatment, and rehabilitation of neurological illnesses and injuries. The leadership of internationally respected physicians keeps Barrow at the forefront of neuroscience. The compassionate expertise of its extensive staff of nurses, technologists, therapists and support personnel is evident in every aspect of care provided.

Our mission is to advance the knowledge and practice of medicine in neuroscience through basic and clinical research, education of medical professionals, and innovation in clinical techniques and technology.

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Submissions from 2009

Pharmacotherapy of cerebral ischemia, Andrew F. Ducruet, Bartosz T. Grobelny, Brad E. Zacharia, Zachary L. Hickman, Mason L. Yeh, and E Sander Connolly

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Endovascular occlusion of a ruptured transitional aneurysm associated with a developmental venous anomaly, Andrew F. Ducruet, Christopher P. Kellner, E. Sander Connolly, and Philip M. Meyers

The complement cascade as a therapeutic target in intracerebral hemorrhage, Andrew F. Ducruet, Brad E. Zacharia, Zachary L. Hickman, Bartosz T. Grobelny, Mason L. Yeh, Sergey A. Sosunov, and E Sander Connolly

Optimisation and data mining techniques for the screening of epileptic patients, Ya-Ju Fan, Wanpracha A. Chaovalitwongse, Chang-Chia Liu, Rajesh C. Sachdeo, Leonidas Iasemidis, and Panos Pardalos

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Impaired terminal differentiation of hippocampal granule neurons and defective contextual memory in PC3/Tis21 knockout mice, Stefano Farioli-Vecchioli, Daniele Saraulli, Marco Costanzi, Luca Leonardi, Irene Cinà, Laura Micheli, Michele Nutini, Patrizia Longone, S. Paul Oh, Vincenzo Cestari, and Felice Tirone

Evidence for angiotensin-converting enzyme 2 as a therapeutic target for the prevention of pulmonary hypertension, Anderson J. Ferreira, Vinayak Shenoy, Yoriko Yamazato, Srinivas Sriramula, Joseph Francis, Lihui Yuan, Ronald K. Castellano, David A. Ostrov, Suk Paul Oh, Michael J. Katovich, and Mohan K. Raizada

Preoperative antiepileptic drug administration and the incidence of postoperative seizures following bur hole-treated chronic subdural hematoma, Bartosz T. Grobelny, Andrew F. Ducruet, Brad E. Zacharia, Zachary L. Hickman, Kristen N. Andersen, Eric Sussman, Austin Carpenter, and E Sander Connolly

Neuronal RAGE expression modulates severity of injury following transient focal cerebral ischemia, Benjamin G. Hassid, M Nathan Nair, Andrew F. Ducruet, Marc L. Otten, Ricardo J. Komotar, David J. Pinsky, Ann Marie Schmidt, Shi Fang Yan, and E Sander Connolly

Decreased mRNA expression of tight junction proteins in lumbar spinal cords of patients with ALS, J. S. Henkel, D. R. Beers, S. Wen, R. Bowser, and S. H. Appel

A Novel Fluorescent α-Conotoxin For The Study Of α7 Nicotinic Acetylcholine Receptors, Arik J. Hone, Paul Whiteaker, Sean Christensen, Yingxian Xiao, Erin L. Meyer, and J. Michael McIntosh

Biomechanics of C-7 transfacet screw fixation: Laboratory investigation, Eric M. Horn, Phillip M. Reyes, Seungwon Baek, Mehmet Senoglu, Nicholas Theodore, Volker K.H. Sonntag, and Neil R. Crawford

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Cortical α7 nicotinic acetylcholine receptor and β-amyloid levels in early Alzheimer disease, Milos D. Ikonomovic, Lynn Wecker, Eric E. Abrahamson, Joanne Wuu, Scott E. Counts, Stephen D. Ginsberg, Elliott J. Mufson, and Steven T. DeKosky

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Optimized, unequal pulse spacing in multiple echo sequences improves refocusing in magnetic resonance, Elizabeth R. Jenista, Ashley M. Stokes, Rosa Tamara Branca, and Warren S. Warren

Neurological and neurobehavioral assessment of experimental subarachnoid hemorrhage, Hyojin Jeon, Jinglu Ai, Mohamed Sabri, Asma Tariq, Xueyuan Shang, Gang Chen, and R. Loch Macdonald

Altered subcellular distribution of c-Abl in alzheimer's disease, Zheng Jing, John Caltagarone, and Robert Bowser

Mechanism-based clustering of genome-wide RNA levels: Roles of transcription and transcript-degradation rates, Sungchul Ji, W. Art Chaovalitwongse, Nina Fefferman, Wonsuk Yoo, and Jose E. Perez-Ortin

Boosting enrollment in neurology trials with Local Identification and Outreach Networks (LIONs)., W N Kernan, C M Viscoli, D Demarco, B Mendes, K Shrauger, J L Schindler, J C McVeety, A Sicklick, D Moalli, P Greco, D M Bravata, S Eisen, L Resor, K Sena, D Story, L M Brass, K L Furie, L Gutmann, E Hinnau, M Gorman, A M Lovejoy, S E Inzucchi, L H Young, and R I Horwitz

Widespread microbial invasion of the chorioamniotic membranes is a consequence and not a cause of intra-amniotic infection, Mi Jeong Kim, Roberto Romero, Maria Teresa Gervasi, Jung Sun Kim, Wonsuk Yoo, Deug Chan Lee, Pooja Mittal, Offer Erez, Juan Pedro Kusanovic, Sonia S. Hassan, and Chong Jai Kim

The complement cascade: new avenues in stroke therapy, Ricardo J. Komotar, Robert M. Starke, Eric J. Arias, Matthew C. Garrett, Marc L. Otten, Maxwell B. Merkow, Benjamin Hassid, J Mocco, Michael E. Sughrue, Grace H. Kim, William J. Mack, Andrew F. Ducruet, and E Sander Connolly

Requirement Of Aqp4 For Antidepressive Efficiency Of Fluoxetine: Implication In Adult Hippocampal Neurogenesis, Hui Kong, Luo Lin Sha, Yi Fan, Ming Xiao, Jian Hua Ding, Jie Wu, and Gang Hu

Chemistry And Pharmacology Of Nicotinic Ligands Based On 6-[5-(Azetidin-2-Ylmethoxy)Pyridin-3-Yl]Hex-5-Yn-1-Ol (Amop-H-Oh) For Possible Use In Depression, Alan P. Kozikowski, J. Brek Eaton, Krishna Mohan Bajjuri, Sheela K. Chellappan, Yihua Chen, Sudhakar Karadi, Rong He, Barbara Caldarone, Michael Manzano, Po Wai Yuen, and Ronald J. Lukas

Subventricular Zone Neural Progenitors From Rapid Brain Autopsies Of Elderly Subjects With And Without Neurodegenerative Disease, Brian W. Leonard, Diego Mastroeni, Andrew Grover, Qiang Liu, Kechun Yang, Ming Gao, Jie Wu, David Pootrakul, Simone A. van, Elly M. Hol, and Joseph Rogers

Anatomical and biomechanical analyses of the unique and consistent locations of sacral insufficiency fractures, Nathan J. Linstrom, Joseph E. Heiserman, Keith E. Kortman, Neil R. Crawford, Seungwon Baek, Russell L. Anderson, Alan M. Pitt, John P. Karis, Jeff S. Ross, Gregory P. Lekovic, and Bruce L. Dean

A Novel Nicotinic Acetylcholine Receptor Subtype In Basal Forebrain Cholinergic Neurons With High Sensitivity To Amyloid Peptides, Qiang Liu, Yao Huang, Fenqin Xue, Alain Simard, Jamie DeChon, Guohui Li, Jianliang Zhang, Linda Lucero, Min Wang, Michael Sierks, Gang Hu, Yongchang Chang, Ronald J. Lukas, and Jie Wu

Knowledge-based variable selection for learning rules from proteomic data, Jonathan L. Lustgarten, Shyam Visweswaran, Robert P. Bowser, William R. Hogan, and Vanathi Gopalakrishnan

Intraoperative magnesium infusion during carotid endarterectomy: a double-blind placebo-controlled trial, William J. Mack, Christopher P. Kellner, Daniel H. Sahlein, Andrew F. Ducruet, Grace H. Kim, J Mocco, Joseph Zurica, Ricardo J. Komotar, Raqeeb Haque, Robert Sciacca, Donald O. Quest, Robert A. Solomon, E Sander Connolly, and Eric J. Heyer

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Tight long-term dynamic doxycycline responsive nigrostriatal GDNF using a single rAAV vector, Fredric P. Manfredsson, Corinna Burger, Aaron C. Rising, Kheir Zuobi-Hasona, Layla F. Sullivan, Alfred S. Lewin, Julia Huang, Emily Piercefield, Nicholas Muzyczka, and Ronald J. Mandel

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Gene therapy for neurological disorders: Challenges and future prospects for the use of growth factors for the treatment of Parkinson's disease, Fredric P. Manfredsson, Michael S. Okun, and Ronald J. Mandel

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AAV9: A potential blood-brain barrier buster, Fredric P. Manfredsson, Aaron C. Rising, and Ronald J. Mandel

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Nigrostriatal rAAV-mediated GDNF overexpression induces robust weight loss in a rat model of age-related obesity, Fredric P. Manfredsson, Nihal Tumer, Benedek Erdos, Tessa Landa, Christopher S. Broxson, Layla F. Sullivan, Aaron C. Rising, Kevin D. Foust, Yi Zhang, Nicholas Muzyczka, Oleg S. Gorbatyuk, Philip J. Scarpace, and Ronald J. Mandel

Nicotinic Acetylcholine Receptor α7 Subunits With A C2 Cytoplasmic Loop Yellow Fluorescent Protein Insertion Form Functional Receptors, Teresa A. Murray, Qiang Liu, Paul Whiteaker, Jie Wu, and Ronald J. Lukas

An investigation of EEG dynamics in an animal model of temporal lobe epilepsy using the maximum Lyapunov exponent, Sandeep P. Nair, Deng-Shan Shiau, Jose C. Principe, Leonidas D. Iasemidis, Panos M. Pardalos, Wendy M. Norman, Paul R. Carney, Kevin M. Kelly, and J Chris Sackellares

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Roles of macrophages in flow-induced outward vascular remodeling, Yoshitsugu Nuki, Melissa M. Matsumoto, Eric Tsang, William L. Young, Nico van Rooijen, Chie Kurihara, and Tomoki Hashimoto

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Elastase-induced intracranial aneurysms in hypertensive mice, Yoshitsugu Nuki, Tsung Ling Tsou, Chie Kurihara, Miyuki Kanematsu, Yasuhisa Kanematsu, and Tomoki Hashimoto

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Roles of matrix metalloproteinases in flow-induced outward vascular remodeling, Ryo Ota, Chie Kurihara, Tsung-Ling Tsou, William L. Young, Yerem Yeghiazarians, Mayland Chang, Shahriar Mobashery, Atsuhiro Sakamoto, and Tomoki Hashimoto

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Brainstem Alzheimer's-like pathology in the triple transgenic mouse model of Alzheimer's disease, Cassia R. Overk, Christy M. Kelley, and Elliott J. Mufson

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Striatal readministration of rAAV vectors reveals an immune response against AAV2 capsids that can be circumvented, Carmen S. Peden, Fredric P. Manfredsson, Sharon K. Reimsnider, Amy E. Poirier, Corinna Burger, Nicholas Muzyczka, and Ronald J. Mandel

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Decreased brain-derived neurotrophic factor depends on amyloid aggregation state in transgenic mouse models of Alzheimer's disease, Shiyong Peng, Diego J. Garzon, Monica Marchese, William Klein, Stephen D. Ginsberg, Beverly M. Francis, Howard T.J. Mount, Elliott J. Mufson, Ahmad Salehi, and Margaret Fahnestock

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β-amyloid deposition and functional impairment in the retina of the APPswe/PS1ΔE9 transgenic mouse model of Alzheimer's disease, Sylvia E. Perez, Stephen Lumayag, Beatrix Kovacs, Elliott J. Mufson, and Shunbin Xu

Nicotine And Inflammatory Neurological Disorders, Wen Hua Piao, Denise Campagnolo, Carlos Dayao, Ronald J. Lukas, Jie Wu, and Fu Dong Shi

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The Arp2/3 complex and WASp are required for apical trafficking of Delta into microvilli during cell fate specification of sensory organ precursors, Akhila Rajan, An Chi Tien, Claire M. Haueter, Karen L. Schulze, and Hugo J. Bellen

Atlantoaxial rotatory subluxation with ligamentous disruption: A blomechanical comparison of current fusion methods, Rogério Rocha, Anna G.U. Sawa, Seungwon Baek, Sam Safavi-Abbasi, Fadimatou Hattendorf, Volker K.H. Sonntag, and Neil R. Crawford

C3a receptor antagonist attenuates brain injury after intracerebral hemorrhage, Michal A. Rynkowski, Grace H. Kim, Matthew C. Garrett, Brad E. Zacharia, Marc L. Otten, Sergei A. Sosunov, Ricardo J. Komotar, Benjamin G. Hassid, Andrew F. Ducruet, John D. Lambris, and E Sander Connolly

Measuring resetting of brain dynamics at epileptic seizures: application of global optimization and spatial synchronization techniques, Shivkumar Sabesan, Niranjan Chakravarthy, Kostas Tsakalis, Panos Pardalos, and Leon Iasemidis

Anterior circulation mouse model of subarachnoid hemorrhage, Mohammed Sabri, Hyojin Jeon, Jinglu Ai, Asma Tariq, Xueyuan Shang, Gang Chen, and R. Loch Macdonald

Hydrogen Peroxide Mobilizes Ca2+ Through Two Distinct Mechanisms In Rat Hepatocytes, Hirohiko Sato, Teruko Takeo, Qiang Liu, Kyoko Nakano, Tomohiro Osanai, Sechiko Suga, Makoto Wakui, and Jie Wu

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Advances in the application of technology to epilepsy: The CIMIT/NIO epilepsy innovation summit, Steven C. Schachter, John Guttag, John Guttag, Steven J. Schiff, Donald L. Schomer, Donald L. Schomer, Massoud Akhtari, Eric M. Bailey, Shirn L. Baptiste, Gregory L. Barkley, John M. Beggs, Renée Béland, Walter Besio, Devin K. Binder, Paolo Bonato, Edward Bromfield, Peter Brunner, Chad Carlson, Sydney S. Cash, Andrew J. Cole, Olivier Commowick, Orrin Devinsky, Werner K. Doyle, Ross Dunseath, Jerome J. Engel, Emad Eskandar, Felipe Fregni, Mark G. Frei, Jacqueline French, Karen Gale, Anne Gallagher, and Nina Graves

A new stand-alone cervical anterior interbody fusion device: Biomechanical comparison with established anterior cervical fixation devices, Matti Scholz, Phillip M. Reyes, Philipp Schleicher, Anna G.U. Sawa, Seungwon Baek, Frank Kandziora, Frederick F. Marciano, and Neil R. Crawford

Nicotinic Attenuation Of Central Nervous System Inflammation And Autoimmunity, Fu Dong Shi, Wen Hua Piao, Yen Ping Kuo, Denise I. Campagnolo, Timothy L. Vollmer, and Ronald J. Lukas

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Splice variants of neuronal nitric oxide synthase are present in the rat kidney, Cheryl Smith, Michael Merchant, Andrea Fekete, Ha Long Nyugen, Paul Oh, You Lin Tain, Jon B. Klein, and Chris Baylis

Cyclooxygenase-1 Or -2 - Which One Mediates Lipopolysaccharide-Induced Hypothermia?, Alexandre A. Steiner, John C. Hunter, Sean M. Phipps, Tatiane B. Nucci, Daniela L. Oliveira, Jennifer L. Roberts, Adrienne C. Scheck, Daniel L. Simmons, and Andrej A. Romanovsky

Biomechanical effects of laminoplasty versus laminectomy: Stenosis and stability, Venkat Subramaniam, Robert H. Chamberlain, Nicholas Theodore, Seungwon Baek, Sam Safavi-Abbasi, Mehmet Senoǧlu, Volker K.H. Sonntag, and Neil R. Crawford

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Bioethical considerations in translational research: Primate stroke, Michael E. Sughrue, J. Mocco, Willam J. Mack, Andrew F. Ducruet, Ricardo J. Komotar, Ruth L. Fischbach, Thomas E. Martin, and E. Sander Connolly

Response to open peer commentaries on "Bioethical considerations in translational research: primate stroke", Michael E. Sughrue, J Mocco, Willam J. Mack, Andrew F. Ducruet, Ricardo J. Komotar, Ruth L. Fischbach, Thomas E. Martin, and E Sander Connolly

Real-time imaging of de novo arteriovenous malformation in a mouse model of hereditary hemorrhagic telangiectasia, Ok Park Sung, Mamta Wankhede, Jae Lee Young, Eun Jung Choi, Naime Fliess, Se Woon Choe, Seh Hoon Oh, Glenn Walter, Mohan K. Raizada, Brian S. Sorg, and S. Paul Oh

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A notch updated, An Chi Tien, Akhila Rajan, and Hugo J. Bellen

Pharmacological And Immunochemical Characterization Of α2 Nicotinic Acetylcholine Receptors (Nachrs) In Mouse Brain, Paul Whiteaker, Jennifer A. Wilking, Robert W.B. Brown, Robert J. Brennan, Allan C. Collins, Jon M. Lindstrom, and Jim Boulter

Nicotine Modulates Gabaergic Transmission To Dopaminergic Neurons In Substantia Nigra Pars Compacta, Cheng Xiao, Ke Chun Yang, Chun Yi Zhou, Guo Zhang Jin, Jie Wu, and Jiang Hong Ye

Impact Of Cigarette Smoking In Type 2 Diabetes Development, Xi Tao Xie, Qiang Liu, Jie Wu, and Makoto Wakui

Prevention of pulmonary hypertension by angiotensin-converting enzyme 2 gene transfer, Yoriko Yamazato, Anderson J. Ferreira, Kwon Ho Hong, Srinivas Sriramula, Joseph Francis, Masanobu Yamazato, Lihui Yuan, Chastity N. Bradford, Vinayak Shenoy, Suk P. Oh, Michael J. Katovich, and Mohan K. Raizada

Distinctive Nicotinic Acetylcholine Receptor Functional Phenotypes Of Rat Ventral Tegmental Area Dopaminergic Neurons, Kechun Yang, Jun Hu, Linda Lucero, Qiang Liu, Chao Zheng, Xuechu Zhen, Guozhang Jin, Ronald J. Lukas, and Jie Wu

Mysterious α6-Containing Nachrs: Function Pharmacology And Pathophysiology, Ke Chun Yang, Guo Zhang Jin, and Jie Wu

Kinetics Of Desensitization And Recovery From Desensitization For Human α4Β2-Nicotinic Acetylcholine Receptors Stably Expressed In Sh-Ep1 Cells, Kewei D. Yu, Qiang Liu, Jie Wu, and Ronald J. Lukas

Renal dysfunction as an independent predictor of outcome after aneurysmal subarachnoid hemorrhage: a single-center cohort study, Brad E. Zacharia, Andrew F. Ducruet, Zachary L. Hickman, Bartosz T. Grobelny, Luis Fernandez, J Michael Schmidt, Reshma Narula, Lauren N. Ko, Margot E. Cohen, Stephan A. Mayer, and E Sander Connolly

Complement inhibition as a proposed neuroprotective strategy following cardiac arrest, Brad E. Zacharia, Zachary L. Hickman, Bartosz T. Grobelny, Peter A. DeRosa, Andrew F. Ducruet, and E Sander Connolly

Agonist- And Antagonist-Induced Conformational Changes Of Loop F And Their Contributions To The ρ1 Gaba Receptor Function, Jianliang Zhang, Fenqin Xue, and Yongchang Chang

U18666A A Cholesterol-Inhibition Agent Modulates Human Neuronal Nicotinic Acetylcholine Receptors Heterologously Expressed In Sh-Ep1 Cell Line, Chao Zheng, Meng Ya Wang, Qiang Liu, Makoto Wakui, Paul Whiteaker, Ronald J. Lukas, and Jie Wu

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Postischemic IGF-1 gene transfer promotes neurovascular regeneration after experimental stroke, Wei Zhu, Yongfeng Fan, Qi Hao, Fanxia Shen, Tomoki Hashimoto, Guo-Yuan Yang, Mehdi Gasmi, Raymond T. Bartus, William L. Young, and Yongmei Chen

Molecular And Toxicologic Research In Newborn Hypospadiac Male Rats Following In Utero Exposure To Di-N-Butyl Phthalate (Dbp), Ying Jian Zhu, Jun Tao Jiang, Long Ma, Jie Zhang, Yan Hong, Kai Liao, Qiang Liu, and Guo Hua Liu

Submissions from 2008

IKK/NF-kappaB regulates skeletal myogenesis via a signaling switch to inhibit differentiation and promote mitochondrial biogenesis, Nadine Bakkar, Jingxin Wang, Katherine J. Ladner, Huating Wang, Jason M. Dahlman, Micheal Carathers, Swarnali Acharyya, Michael A. Rudnicki, Andrew D. Hollenbach, and Denis C. Guttridge

Biomechanical comparison of occipitoatlantal screw fixation techniques: Laboratory investigation, Nicholas C. Bambakidis, Iman Feiz-Erfan, Eric M. Horn, L. Fernando Gonzalez, Seungwon Baek, K. Zafer Yüksel, Anna G.U. Brantley, Volker K.H. Sonntag, and Neil R. Crawford

Hypothalamic Hamartomas Associated With Epilepsy: Ultrastructural Features, John Beggs, Satoko Nakada, Kristina Fenoglio, Jie Wu, Stephen Coons, and John F. Kerrigan

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RAX is required for fly neuronal development and mouse embryogenesis, Richard L. Bennett, William L. Blalock, Eun Jung Choi, Young J. Lee, Yanping Zhang, Lei Zhou, S. Paul Oh, and W. Stratford May

TIS21/BTG2 negatively regulates estradiol-stimulated expansion of hematopoietic stem cells by derepressing Akt phosphorylation and inhibiting mTOR signal transduction, Cho Kim Bong, Sook Ryu Min, S. Paul Oh, and Kyoung Lim In

YKL-40, a marker of simian immunodeficiency virus encephalitis, modulates the biological activity of basic fibroblast growth factor, Dafna Bonneh-Barkay, Stephanie J. Bissel, Gouji Wang, Kenneth N. Fish, Georgina C.B. Nicholl, Samuel W. Darko, Rafael Medina-Flores, Michael Murphey-Corb, Premeela A. Rajakumar, Julia Nyaundi, John W. Mellors, Robert Bowser, and Clayton A. Wiley

Perinatal loss of Nkx2-5 results in rapid conduction and contraction defects, Laura E. Briggs, Morihiko Takeda, Adolfo E. Cuadra, Hiroko Wakimoto, Melissa H. Marks, Alexandra J. Walker, Tsugio Seki, Suk P. Oh, Jonathan T. Lu, Colin Sumners, Mohan K. Raizada, Nobuo Horikoshi, Ellen O. Weinberg, Kenji Yasui, Yasuhiro Ikeda, Kenneth R. Chien, and Hideko Kasahara

Negative-feedback regulation of proneural proteins controls the timing of neural precursor division, Pao-Ju Chang, Yun-Ling Hsiao, An-Chi Tien, Yi-Chen Li, and Haiwei Pi

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Galanin hyperinnervation upregulates choline acetyltransferase expression in cholinergic basal forebrain neurons in Alzheimer's disease, Scott E. Counts, Bin He, Shaoli Che, Stephen D. Ginsberg, and Elliott J. Mufson

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Galanin in Alzheimer's disease: Neuroinhibitory or neuroprotective?, S. E. Counts, S. E. Perez, and E. J. Mufson

Biomechanical consequences of cervical spondylectomy versus corpectomy, Şeref Doǧan, Seungwon Baek, Volker K.H. Sonntag, and Neil R. Crawford

Hypersensitivity Of Aquaporin 4-Deficient Mice To 1-Methyl-4-Phenyl-1236-Tetrahydropyrindine And Astrocytic Modulation, Yi Fan, Hui Kong, Xueru Shi, Xiulan Sun, Jianhua Ding, Jie Wu, and Gang Hu

Interactive effect of sulfur and nitrogen on nitrogen accumulation and harvest in oilseed crops differing in nitrogen assimilation potential, I. S. Fazili, A. Jamal, S. Ahmad, Muzain Masoodi, J. S. Khan, and M. Z. Abdin

The pterional-transsylvian approach: An analytical study, Eberval Gadelha Figueiredo, Pushpa Deshmukh, Joseph M. Zabramski, Mark C. Preul, Neil R. Crawford, and Robert F. Spetzler

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The phosphorylation state of Ser-129 in human α-synuclein determines neurodegeneration in a rat model of Parkinson disease, Oleg S. Gorbatyuk, Shoudong Li, Layla F. Sullivan, Weijun Chen, Galina Kondrikova, Fredric P. Manfredsson, Ronald J. Mandel, and Nicholas Muzyczka

Helmet use and associated spinal fractures in motorcycle crash victims, Pamela W. Goslar, Neil R. Crawford, Scott R. Petersen, Jeffrey R. Wilson, and Timothy Harrington

Tnk1/Kos1 knockout mice develop spontaneous tumors, Sarasija Hoare, Kishalay Hoare, Mary K. Reinhard, Young J. Lee, S. Paul Oh, and W. Stratford May

Genetic ablation of the Bmpr2 gene in pulmonary endothelium is sufficient to predispose to pulmonary arterial hypertension, Kwon Ho Hong, Young Jae Lee, Eunji Lee, Sung Ok Park, Chul Han, Hideyuki Beppu, En Li, Mohan K. Raizada, Kenneth D. Bloch, and S. Paul Oh

Transfacet screw placement for posterior fixation of C-7: Technical note, Eric M. Horn, Nicholas Theodore, Neil R. Crawford, Nicholas C. Bambakidis, and Volker K.H. Sonntag

αConotoxin Arenatus Ib[V11Lv16D] Is A Potent And Selective Antagonist At Rat And Human Native α7 Nicotinic Acetylcholine Receptors, Neal Innocent, Phil D. Livingstone, Arik Hone, Atsuko Kimura, Tracey Young, Paul Whiteaker, J. Michael McIntosh, and Susan Wonnacott

Voltage-gated K+ channel dysfunction in myocytes from a dog model of subarachnoid hemorrhage, Babak S. Jahromi, Yasuo Aihara, Jinglu Ai, Zhen Du Zhang, Elena Nikitina, and Robert Loch MacDonald

Preserved BK channel function in vasospastic myocytes from a dog model of subarachnoid hemorrhage, Babak S. Jahromi, Yasuo Aihara, Jinglu Ai, Zhen Du Zhang, George Weyer, Elena Nikitina, Reza Yassari, Khaled M. Houamed, and R. Loch MacDonald

Temporal profile of potassium channel dysfunction in cerebrovascular smooth muscle after experimental subarachnoid haemorrhage, Babak S. Jahromi, Yasuo Aihara, Jinglu Ai, Zhen Du Zhang, George Weyer, Elena Nikitina, Reza Yassari, Khaled M. Houamed, and R. Loch Macdonald

Biomechanical comparison of a novel C1 posterior locking plate with the harms technique in a C1-C2 fixation model, Brian P. Kelly, John A. Glaser, and Denis J. DiAngelo

Biomechanical testing of a novel four-rod technique for lumbo-pelvic reconstruction, Brian P. Kelly, Francis H. Shen, John S. Schwab, Vincent Arlet, and Denis J. Diangelo

Gabaa Receptor-Mediated Activation Of L-Type Calcium Channels Induces Neuronal Excitation In Surgically Resected Human Hypothalamic Hamartomas, Do Young Kim, Kristina A. Fenoglio, Timothy A. Simeone, Stephen W. Coons, Jie Wu, Yongchang Chang, John F. Kerrigan, and Jong M. Rho

Protective effect of C5a receptor inhibition after murine reperfused stroke, Grace H. Kim, J Mocco, David K. Hahn, Christopher P. Kellner, Ricardo J. Komotar, Andrew F. Ducruet, William J. Mack, and E Sander Connolly

The role of complement in stroke therapy, Ricardo J. Komotar, Grace H. Kim, Marc L. Otten, Benjamin Hassid, J Mocco, Michael E. Sughrue, Robert M. Starke, William J. Mack, Andrew F. Ducruet, Maxwell B. Merkow, Matthew C. Garrett, and E Sander Connolly

Quantitative analysis of exposure of staged orbitozygomatic and retrosigmoid craniotomies for lesions of the clivus with supratentorial extension., Andrew S. Little, Pakrit Jittapiromsak, Neil R. Crawford, Pushpa Deshmukh, Mark C. Preul, Robert F. Spetzler, and Nicholas C. Bambakidis

Agonist-Induced Hump Current Production In Heterologously-Expressed Human α4β2-Nicotinic Acetylcholine Receptors, Qiang Liu, Ke Wei Yu, Yong Chang, Ronald J. Lukas, and Jie Wu

Using a novel resource to decrease proteomic biomarker identification time., Jonathan L. Lustgarten, Shyam Visweswaran, Himanshu Grover, Chad P. Kimmel, Henrik Ryberg, Robert P. Bowser, Vanathi Gopalakrishnan, and William R. Hogan