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Submissions from 2021

The M1311V variant of ATP7A is associated with impaired trafficking and copper homeostasis in models of motor neuron disease, Nadine Bakkar, Alexander Starr, Benjamin E. Rabichow, Ileana Lorenzini, Zachary T. McEachin, Robert Kraft, Matthew Chaung, Sam Macklin-Isquierdo, Taylor Wingfield, Briggs Carhart, Nathan Zahler, Wen Hsuan Chang, Gary J. Bassell, Alexandre Betourne, Nicholas Boulis, Samuel V. Alworth, Justin K. Ichida, Paul R. August, Daniela C. Zarnescu, Rita Sattler, and Robert Bowser

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ALSUntangled #60: light therapy, Richard Bedlack, Paul Barkhaus, Ben Barnes, Michael Bereman, Tulio Bertorini, Gregory Carter, Jesse Crayle, Sky Kihuwa-Mani, Robert Bowser, Pamela Kittrell, Christopher McDermott, Gary Pattee, Kristiana Salmon, and Paul Wicks

Radicava/Edaravone Findings in Biomarkers From Amyotrophic Lateral Sclerosis (REFINE-ALS): Protocol and Study Design, James Berry, Benjamin Brooks, Angela Genge, Terry Heiman-Patterson, Stanley Appel, Michael Benatar, Robert Bowser, Merit Cudkowicz, Clifton Gooch, Jeremy Shefner, Jurjen Westra, Wendy Agnese, Charlotte Merrill, Sally Nelson, and Stephen Apple

Complement C3a receptor-mediated vascular dysfunction: A complex interplay between aging and neurodegeneration, Kanchan Bhatia, Saif Ahmad, Adam Kindelin, and Andrew F. Ducruet

Implications of Oligomeric Amyloid-Beta (oAβ, Andrew A. George, Jaime M Vieira, Cameron Xavier-Jackson, Michael T Gee, John R Cirrito, Heather A Bimonte-Nelson, Marina R Picciotto, Ronald J. Lukas, and Paul Whiteaker

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Association of Variants in the SPTLC1 Gene With Juvenile Amyotrophic Lateral Sclerosis, Janel O. Johnson, Ruth Chia, Danny E. Miller, Rachel Li, Ravindran Kumaran, Yevgeniya Abramzon, Nada Alahmady, Alan E. Renton, Simon D. Topp, J Raphael Gibbs, Mark R. Cookson, Marya S. Sabir, Clifton L. Dalgard, Claire Troakes, Ashley R. Jones, Aleksey Shatunov, Alfredo Iacoangeli, Ahmad Al Khleifat, Nicola Ticozzi, Vincenzo Silani, Cinzia Gellera, Ian P. Blair, Carol Dobson-Stone, John B. Kwok, Emily S. Bonkowski, Robin Palvadeau, Pentti J. Tienari, Karen E. Morrison, Pamela J. Shaw, Ammar Al-Chalabi, Robert H. Brown, and Andrea Calvo

Neutrophil Extracellular Traps Promote the Development of Intracranial Aneurysm Rupture, Masaaki Korai, James Purcell, Yoshinobu Kamio, Kazuha Mitsui, Hajime Furukawa, Kimihiko Yokosuka, Takeshi Miyamoto, Hitomi Sato, Hiroki Sato, Satoru Eguchi, Jinglu Ai, Michael T. Lawton, and Tomoki Hashimoto

Human papillomavirus vaccine guideline adherence among Arizona's Medicaid beneficiaries, Alexis Koskan, Lynne Klasko-Foster, Chad Stecher, Sue Rodriguez, Deborah Helitzer, and Wonsuk Yoo

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TDP-43 proteinopathy alters the ribosome association of multiple mRNAs including the glypican Dally-like protein (Dlp)/GPC6, Erik M. Lehmkuhl, Suvithanandhini Loganathan, Eric Alsop, Alexander D. Blythe, Tina Kovalik, Nicholas P. Mortimore, Dianne Barrameda, Chuol Kueth, Randall J. Eck, Bhavani B. Siddegowda, Archi Joardar, Hannah Ball, Maria E. Macias, Robert Bowser, Kendall Van Keuren-Jensen, and Daniela C. Zarnescu

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ActRIIB:ALK4-Fc alleviates muscle dysfunction and comorbidities in murine models of neuromuscular disorders, Jia Li, Maureen Fredericks, Marishka Cannell, Kathryn Wang, Dianne Sako, Michelle C. Maguire, Rosa Grenha, Katia Liharska, Lavanya Krishnan, Troy Bloom, Elitza P. Belcheva, Pedro A. Martinez, Roselyne Castonguay, Sarah Keates, Mark J. Alexander, Hyunwoo Choi, Asya V. Grinberg, R. Scott Pearsall, Paul Oh, Ravindra Kumar, and Rajasekhar N.V.S. Suragani

Generation of two induced pluripotent stem cell (iPSC) lines from an ALS patient with simultaneous mutations in KIF5A and MATR3 genes, David X. Medina, Ashley Boehringer, Marissa Dominick, Ileana Lorenzini, Sara Saez-Atienzar, Erik P. Pioro, Rita Sattler, Bryan Traynor, and Robert Bowser

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Tocilizumab is safe and tolerable and reduces C-reactive protein concentrations in the plasma and cerebrospinal fluid of ALS patients, Carol Milligan, Nazem Atassi, Suma Babu, Richard J. Barohn, James B. Caress, Merit E. Cudkowicz, Armineuza Evora, Gregory A. Hawkins, Marlena Wosiski-Kuhn, Eric A. Macklin, Jeremy M. Shefner, Zachary Simmons, Robert P. Bowser, and Shafeeq S. Ladha

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Evaluation of amyotrophic lateral sclerosis-induced muscle degeneration using magnetic resonance-based relaxivity contrast imaging (RCI), Sudarshan Ragunathan, Laura C. Bell, Natenael Semmineh, Ashley M. Stokes, Jeremy M. Shefner, Robert Bowser, Shafeeq Ladha, and C. Chad Quarles

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ALSUntangled 55: vitamin E (α-tocopherol), Bedlack Richard, Jesse Crayle, Carmel Armon, Paul Barkhaus, Benjamin Barnes, Michael Benatar, Tulio Bertorini, Robert Bowser, Mark Bromberg, Benjamin Brooks, Lev Brylev, James Caress, Greg Carter, Merit Cudkowicz, Jon Glass, Volkan Granit, Michael Graves, Terri Heiman-Patterson, Leann Jiang, Christopher McDermott, Gary Pattee, Erik Pioro, Michael Rivner, Jeffrey Rothstein, Kristiana Salmon, Kim Staats, and Paul Wicks

To Zoom or Not to Zoom: The Should I Travel Index Revisited during the Coronavirus Disease Pandemic, Seward B. Rutkove, Jeremy M. Shefner, Robert Bowser, Martin R. Turner, and Michael Benatar

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Gene expression profiling of brain endothelial cells after experimental subarachnoid haemorrhage, Michael K. Tso, Paul Turgeon, Bert Bosche, Charles K. Lee, Tian Nie, Josephine D’Abbondanza, Jinglu Ai, Philip A. Marsden, and R. Loch Macdonald

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Defining the Caprin-1 Interactome in Unstressed and Stressed Conditions, Lucas Vu, Asmita Ghosh, Chelsea Tran, Walters Aji Tebung, Hadjara Sidibé, Krystine Garcia-Mansfield, Victoria David-Dirgo, Ritin Sharma, Patrick Pirrotte, Robert Bowser, and Christine Vande Velde

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Role of perivascular and meningeal macrophages in outcome following experimental subarachnoid hemorrhage, Hoyee Wan, Shakira Brathwaite, Jinglu Ai, Kullervo Hynynen, and R. Loch Macdonald

Role of perivascular and meningeal macrophages in outcome following experimental subarachnoid hemorrhage, Hoyee Wan, Shakira Brathwaite, Jinglu Ai, Kullervo Hynynen, and R. Loch Macdonald

Blood-spinal cord barrier leakage is independent of motor neuron pathology in ALS, Sarah Waters, Molly E. Swanson, Birger V. Dieriks, Yibin B. Zhang, Natasha L. Grimsey, Helen C. Murray, Clinton Turner, Henry J. Waldvogel, Richard L. Faull, Jiyan An, Robert Bowser, Maurice A. Curtis, Mike Dragunow, and Emma Scotter

Submissions from 2020

C3a receptor antagonist therapy is protective with or without thrombolysis in murine thromboembolic stroke., Saif Ahmad, Chirayu Pandya, Adam Kindelin, Kanchan Bhatia, Rafay Chaudhary, Alok Kumar Dwivedi, Jennifer M Eschbacher, Qiang Liu, Michael F Waters, Md Nasrul Hoda, and Andrew F. Ducruet

Selective inversion recovery quantitative magnetization transfer imaging: Toward a 3 T clinical application in multiple sclerosis., Francesca Bagnato, Giulia Franco, Fei Ye, Run Fan, Patricia Commiskey, Seth A Smith, Junzhong Xu, and Richard Dortch

ALSUntangled 56: “ten red flags”-things to be wary of in alternative or off-label products, Richard Bedlack, Carmel Armon, Paul Barkhaus, Benjamin Barnes, Michael Benatar, Michael Bereman, Robert Bowser, Mark Bromberg, Lev Brylev, James Caress, Greg Carter, Amy Chen, Nick Cole, Jesse Crayle, Merit Cudkocwicz, Eva Feldman, Americo Fernandes, Stephen Goutman, Volkan Granit, Lawrence Hayward, Carlayne Jackson, Leanne Jiang, Pamela Kittrell, Stephen Kolb, Nicholas Maragakis, Christopher McDermott, Kathy Mitchell, Natasha Olby, Lyle Ostrow, Sabrina Paganoni, and Gary Pattee

Analysis of postprocessing steps for residue function dependent dynamic susceptibility contrast (DSC)-MRI biomarkers and their clinical impact on glioma grading for both 1.5 and 3T., Laura C Bell, A. Stokes, and C. Quarles

Radicava / edaravone findings in biomarkers from ALS (REFINE ALS): Protocol and study design, James Berry, Benjamin Brooks, Angela Genge, Terry Heiman-Patterson, Stanley Appel, Michael Benatar, Robert Bowser, Merit Cudkowicz, Clifton Gooch, Jeremy Shefner, Jurjen Westra, Wendy Agnese, Charlotte Merrill, Sally Nelson, and Stephen Apple

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Range of Motion Testing of a Novel 3D-Printed Synthetic Spine Model., Michael A Bohl, Sarah McBryan, Anna G U S Newcomb, Jennifer N Lehrman, Brian P. Kelly, Peter Nakaji, Steve W Chang, Juan S. Uribe, Jay D Turner, and U Kumar Kakarla

Time-delimited signaling of MET receptor tyrosine kinase regulates cortical circuit development and critical period plasticity., Ke Chen, Xiaokuang Ma, Antoine Nehme, Jing Wei, Yan Cui, Yuehua Cui, Dezhong Yao, Jie Wu, Trent Anderson, Deveroux Ferguson, Pat Levitt, and Shenfeng Qiu

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RBM45 associates with nuclear stress bodies and forms nuclear inclusions during chronic cellular stress and in neurodegenerative diseases, Mahlon Collins, Yang Li, and Robert Bowser

Rapid whole-brain quantitative magnetization transfer imaging using 3D selective inversion recovery sequences., Matthew J Cronin, Junzhong Xu, Francesca Bagnato, Daniel F Gochberg, John C Gore, and Richard Dortch

Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis., Ramita Dewan, Ruth Chia, Jinhui Ding, Richard A Hickman, Thor D Stein, Yevgeniya Abramzon, Sarah Ahmed, Marya S Sabir, Makayla K Portley, Arianna Tucci, Kristina Ibáñez, F N U Shankaracharya, Pamela Keagle, Giacomina Rossi, Paola Caroppo, Fabrizio Tagliavini, Maria L Waldo, Per M Johansson, Christer F Nilsson, James B Rowe, Luisa Benussi, Giuliano Binetti, Roberta Ghidoni, Edwin Jabbari, Coralie Viollet, Jonathan D Glass, Andrew B Singleton, Vincenzo Silani, Owen A Ross, Mina Ryten, Ali Torkamani, Toshiko Tanaka, Luigi Ferrucci, Susan M Resnick, Stuart Pickering-Brown, Christopher B Brady, Neil Kowal, John A Hardy, Vivianna Van Deerlin, Jean Paul Vonsattel, Matthew B Harms, Huw R Morris, Raffaele Ferrari, John E Landers, Adriano Chiò, J Raphael Gibbs, Clifton L Dalgard, Sonja W Scholz, Bryan J Traynor, and Robert Bowser

Diffusion Tensor Tractrography Visualizes Partial Nerve Laceration Severity as Early as 1 Week After Surgical Repair in a Rat Model Ex Vivo., Angel F Farinas, Isaac V Manzanera Esteve, Alonda C Pollins, Nancy L Cardwell, Mark D Does, Richard Dortch, and Wesley P Thayer

Mast Cell Promotes the Development of Intracranial Aneurysm Rupture, Hajime Furukawa, Kosuke Wada, Yoshiteru Tada, Atsushi Kuwabara, Hiroki Sato, Jinglu Ai, Michael T. Lawton, and Tomoki Hashimoto

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Mast Cell Promotes the Development of Intracranial Aneurysm Rupture, Hajime Furukawa, Kosuke Wada, Yoshiteru Tada, Atsushi Kuwabara, Hiroki Sato, Jinglu Ai, Michael T. Lawton, and Tomoki Hashimoto

Dual Effect of 5-HT, Ming Gao, Taleen S Der-Ghazarian, Shuangtao Li, Shenfeng Qiu, Janet L Neisewander, and Jie Wu

Optimizing biomechanics of anterior column realignment for minimally invasive deformity correction., Jakub Godzik, Bernardo de Andrada Pereira, Anna G U S Newcomb, Jennifer N Lehrman, Gregory M Mundis, Randall J Hlubek, Juan S. Uribe, Brian P. Kelly, and Jay D Turner

A multi-center study of neurofilament assay reliability and inter-laboratory variability, Elizabeth Gray, Patrick Oeckl, Maria D.M. Amador, Ulf Andreasson, Jiyan An, Kaj Blennow, Robert Bowser, Maxim De Schaepdryver, Amanda Heslegrave, Jens Kuhle, Aleksandra Maceski, Marleen Koel-Simmelink, Foudil Lamari, Vittoria Lombardi, Andrea Malaspina, Irina Nilsson, Koen Poesen, François Salachas, Petra Steinacker, Charlotte E. Teunissen, Philip Van Damme, Henrik Zetterberg, Albert Ludolph, Andreas Jeromin, Martin R. Turner, and Markus Otto

Expression profiling of precuneus layer III cathepsin D-immunopositive pyramidal neurons in mild cognitive impairment and Alzheimer's disease: Evidence for neuronal signaling vulnerability., Bin He, Sylvia E Perez, Sang H Lee, Stephen D Ginsberg, Michael Malek-Ahmadi, and Elliott J. Mufson

Longitudinal biomarkers in amyotrophic lateral sclerosis, Fen Huang, Yuda Zhu, Jennifer Hsiao-Nakamoto, Xinyan Tang, Jason C. Dugas, Miriam Moscovitch-Lopatin, Jonathan D. Glass, Robert H. Brown, Shafeeq S. Ladha, David Lacomis, Jeffrey M. Harris, Kimberly Scearce-Levie, Carole Ho, Robert Bowser, and James D. Berry

Smartphone-based meditation for myeloproliferative neoplasm patients: Feasibility study to inform future trials, Jennifer Huberty, Ryan Eckert, Linda Larkey, Jonathan Kurka, Sue A.Rodriguez De Jesus, Wonsuk Yoo, and Ruben Mesa

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Norepinephrine metabolite DOPEGAL activates AEP and pathological Tau aggregation in locus coeruleus., Seong Su Kang, Xia Liu, Eun Hee Ahn, Jie Xiang, Fredric P Manfredsson, Xifei Yang, Hongbo R Luo, L Cameron Liles, David Weinshenker, and Keqiang Ye

ZPR1 prevents R-loop accumulation, upregulates SMN2 expression and rescues spinal muscular atrophy, Annapoorna Kannan, Xiaoting Jiang, Lan He, Saif Ahmad, and Laxman Gangwani

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Overexpression of activin receptor-like kinase 1 in endothelial cells suppresses development of arteriovenous malformations in mouse models of hereditary hemorrhagic telangiectasia, Yong Hwan Kim, Phuong Nhung Vu, Se Woon Choe, Chang Jin Jeon, Helen M. Arthur, Calvin P.H. Vary, Young Jae Lee, and S. Paul Oh

Evaluation of abnormal styloid anatomy as a cause of internal jugular vein compression using a 3D-printed model: a laboratory investigation., Jennifer N Lehrman, Mohan Narayanan, Claudio Cavallo, Anna G U S Newcomb, Xiaochun Zhao, Brian P. Kelly, Neil R Crawford, and Peter Nakaji

Braak Stage, Cerebral Amyloid Angiopathy, and Cognitive Decline in Early Alzheimer's Disease., Michael Malek-Ahmadi, Sylvia E Perez, Kewei Chen, and Elliott J. Mufson

Cocaine potently blocks neuronal α, Ze-Gang Ma, Nan Jiang, Yuan-Bing Huang, Xiao-Kuang Ma, Jason Brek Eaton, Ming Gao, Yong-Chang Chang, Ronald J. Lukas, Paul Whiteaker, Janet Neisewander, and Jie Wu

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Intravenously Administered, Retinoid Activating Nanoparticles Increase Lifespan and Reduce Neurodegeneration in the SOD1, David X. Medina, Eugene P Chung, Collin D Teague, Robert Bowser, and Rachael W Sirianni

TLR4 (Toll-Like Receptor 4) Mediates the Development of Intracranial Aneurysm Rupture., Kazuha Mitsui, Taichi Ikedo, Yoshinobu Kamio, Hajime Furukawa, Michael T. Lawton, and Tomoki Hashimoto

TMEM100 is a key factor for specification of lymphatic endothelial progenitors, Eun Hye Moon, Yong Hwan Kim, Phuong Nhung Vu, Hyunjin Yoo, Kwonho Hong, Young Jae Lee, and S. Paul Oh

The Hitchhiker's Guide to Nucleocytoplasmic Trafficking in Neurodegeneration., Stephen Moore, Benjamin E Rabichow, and Rita Sattler

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Frontal cortex chitinase and pentraxin neuroinflammatory alterations during the progression of Alzheimer's disease., Marta Moreno-Rodriguez, Sylvia E Perez, Muhammad Nadeem, Michael Malek-Ahmadi, and Elliott J. Mufson

Remote Ischemic Post-Conditioning Therapy is Protective in Mouse Model of Traumatic Optic Neuropathy, Muhammad Nadeem, Adam Kindelin, Laura Mahady, Kanchan Bhatia, Md Nasrul Hoda, Andrew F. Ducruet, and Saif Ahmad

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Length-dependent MRI of hereditary neuropathy with liability to pressure palsies., Michael Pridmore, Ryan Castoro, Megan Simmons McCollum, Hakmook Kang, Jun Li, and Richard Dortch

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Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia., Mercedes Prudencio, Jack Humphrey, Sarah Pickles, Anna-Leigh Brown, Sarah E Hill, Jennifer M Kachergus, J Shi, Michael G Heckman, Matthew R Spiegel, Casey Cook, Yuping Song, Mei Yue, Lillian M Daughrity, Yari Carlomagno, Karen Jansen-West, Cristhoper Fernandez de Castro, Michael DeTure, Shunsuke Koga, Ying-Chih Wang, Prasanth Sivakumar, Cristian Bodo, Ana Candalija, Kevin Talbot, Bhuvaneish T Selvaraj, Karen Burr, Siddharthan Chandran, Jia Newcombe, Tammaryn Lashley, Isabel Hubbard, Demetra Catalano, Duyang Kim, Nadia Propp, Samantha Fennessey, Delphine Fagegaltier, Hemali Phatnani, Maria Secrier, Elizabeth Mc Fisher, Björn Oskarsson, Marka van Blitterswijk, Rosa Rademakers, Neil R Graff-Radford, Bradley F Boeve, David S Knopman, Ronald C Petersen, Keith A Josephs, E Aubrey Thompson, Towfique Raj, Michael Ward, Dennis W Dickson, Tania F Gendron, Pietro Fratta, Leonard Petrucelli, and Robert Bowser

Correcting Smad1/5/8, mTOR, and VEGFR2 treats pathology in hereditary hemorrhagic telangiectasia models, Santiago Ruiz, Haitian Zhao, Pallavi Chandakkar, Julien Papoin, Hyunwoo Choi, Aya Nomura-Kitabayashi, Radhika Patel, Matthew Gillen, Li Diao, Prodyot K. Chatterjee, Mingzhu He, Yousef Al-Abed, Ping Wang, Christine N. Metz, S. Paul Oh, Lionel Blanc, Fabien Campagne, and Philippe Marambaud

Identification of a pathogenic intronic KIF5A mutation in an ALS-FTD kindred, Sara Saez-Atienzar, Clifton L. Dalgard, Jinhui Ding, Adriano Chiò, Camile Alba, Dan N. Hupalo, Matthew D. Wilkerson, Robert Bowser, Erik P. Pioro, Richard Bedlack, and Bryan J. Traynor

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Global alterations to the choroid plexus blood-CSF barrier in amyotrophic lateral sclerosis, J. Saul, E. Hutchins, R Reiman, M Saul, L W. Ostrow, B T. Harris, K Van Keuren-Jensen, R Bowser, and N Bakkar

Variations among human lumbar spine segments and their relationships to in vitro biomechanics: A retrospective analysis of 281 motion segments from 85 cadaveric spines, Anna G.U. Sawa, Jennifer N. Lehrman, Neil R. Crawford, and Brian P. Kelly

Systematic assessment of multi-echo dynamic susceptibility contrast MRI using a digital reference object., A. Stokes, Natenael B Semmineh, Ashley Nespodzany, Laura C Bell, and C. Quarles

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YAP-dependent necrosis occurs in early stages of Alzheimer's disease and regulates mouse model pathology., Hikari Tanaka, Hidenori Homma, Kyota Fujita, Kanoh Kondo, Shingo Yamada, Xiaocen Jin, Masaaki Waragai, Gaku Ohtomo, Atsushi Iwata, Kazuhiko Tagawa, Naoki Atsuta, Masahisa Katsuno, Naoki Tomita, Katsutoshi Furukawa, Yuko Saito, Takashi Saito, Ayaka Ichise, Shinsuke Shibata, Hiroyuki Arai, Takaomi Saido, Marius Sudol, Shin-Ichi Muramatsu, Hideyuki Okano, Elliott J. Mufson, Gen Sobue, Shigeo Murayama, and Hitoshi Okazawa

Robotic Spine Surgery: Current State in Minimally Invasive Surgery, Chau D. Vo, Bowen Jiang, Tej D. Azad, Neil R. Crawford, Ali Bydon, and Nicholas Theodore

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Cross-sectional and longitudinal measures of chitinase proteins in amyotrophic lateral sclerosis and expression of CHI3L1 in activated astrocytes., Lucas Vu, Jiyan An, Tina Kovalik, Tania Gendron, Leonard Petrucelli, and Robert Bowser

Patterns and disparities in human papillomavirus (HPV) vaccine uptake for young female adolescents among U.S. States: NIS-teen (2008–2016), Wonsuk Yoo, Alexis Koskan, Matthew Scotch, Heidi Pottinger, Warner K. Huh, and Deborah Helitzer

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CRISPR-mediated gene correction links the ATP7A M1311V mutations with amyotrophic lateral sclerosis pathogenesis in one individual., Yeomin Yun, Sung-Ah Hong, Ka-Kyung Kim, Daye Baek, Dongsu Lee, Ashwini M Londhe, Minhyung Lee, Jihyeon Yu, Zachary T McEachin, Gary J Bassell, Robert Bowser, Chadwick M Hales, Sung-Rae Cho, Janghwan Kim, Ae Nim Pae, Eunji Cheong, Sangwoo Kim, Nicholas M Boulis, Sangsu Bae, and Yoon Ha

Submissions from 2019

Neuropathological Correlates Of Amyloid Pet Imaging In Down Syndrome, Eric E. Abrahamson, Elizabeth Head, Ira T. Lott, Benjamin L. Handen, Elliott J. Mufson, Bradley T. Christian, William E. Klunk, and Milos D. Ikonomovic

The Role of Complement C3a Receptor in Stroke, Saif Ahmad, Kanchan Bhatia, Adam Kindelin, and Andrew F. Ducruet

Acetyl-11-keto-β-boswellic acid (AKBA) Attenuates Oxidative Stress, Inflammation, Complement Activation and Cell Death in Brain Endothelial Cells Following OGD/Reperfusion, Saif Ahmad, Shah Alam Khan, Adam Kindelin, Tasha Mohseni, Kanchan Bhatia, Md Nasrul Hoda, and Andrew F. Ducruet

C3a receptor inhibition protects brain endothelial cells against oxygen-glucose deprivation/reperfusion, Saif Ahmad, Adam Kindelin, Shah Alam Khan, Maaz Ahmed, Md Nasrul Hoda, Kanchan Bhatia, and Andrew F. Ducruet

First spine surgery utilizing real-time image-guided robotic assistance, A. Karim Ahmed, Corinna C. Zygourakis, Samuel Kalb, Alex M. Zhu, Camilo A. Molina, Bowen Jiang, Ari M. Blitz, Ali Bydon, Neil R. Crawford, and Nicholas Theodore

Shared polygenic risk and causal inferences in amyotrophic lateral sclerosis, Sara Bandres-Ciga, Alastair J. Noyce, Gibran Hemani, Aude Nicolas, Andrea Calvo, Gabriele Mora, Alessandro Arosio, Marco Barberis, Ilaria Bartolomei, Stefania Battistini, Michele Benigni, Giuseppe Borghero, Maura Brunetti, Stefania Cammarosano, Antonino Cannas, Antonio Canosa, Margherita Capasso, Claudia Caponnetto, Carla Caredda, Paola Carrera, Federico Casale, Sebastiano Cavallaro, Adriano Chiò, Tiziana Colletti, Francesca L. Conforti, Amelia Conte, Lucia Corrado, Emanuela Costantino, Sandra D'Alfonso, Antonio Fasano, and Cinzia Femiano

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Shared polygenic risk and causal inferences in amyotrophic lateral sclerosis, Sara Bandres-Ciga, Alastair J. Noyce, Gibran Hemani, Aude Nicolas, Andrea Calvo, Gabriele Mora, Alessandro Arosio, Marco Barberis, Ilaria Bartolomei, Stefania Battistini, Michele Benigni, Giuseppe Borghero, Maura Brunetti, Stefania Cammarosano, Antonino Cannas, Antonio Canosa, Margherita Capasso, Claudia Caponnetto, Carla Caredda, Paola Carrera, Federico Casale, Sebastiano Cavallaro, Adriano Chiò, Tiziana Colletti, Francesca L. Conforti, Amelia Conte, Lucia Corrado, Emanuela Costantino, Sandra D'Alfonso, Antonio Fasano, Cinzia Femiano, and Carlo Ferrarese

Recent Advances in Basic Research for Brain Arteriovenous Malformation, Leandro Barbosa Do Prado, Chul Han, S. Paul Oh, and Hua Su

Evaluating Multisite Rcbv Consistency From Dsc-Mri Imaging Protocols And Postprocessing Software Across The Nci Quantitative Imaging Network Sites Using A Digital Reference Object (Dro), Laura C. Bell, Natenael Semmineh, Hongyu An, Cihat Eldeniz, Richard Wahl, Kathleen M. Schmainda, Melissa A. Prah, Bradley J. Erickson, Panagiotis Korfiatis, Chengyue Wu, Anna G. Sorace, Thomas E. Yankeelov, Neal Rutledge, Thomas L. Chenevert, Dariya Malyarenko, Yichu Liu, Andrew Brenner, Lel S. Hu, Yuxiang Zhou, Jerrold L. Boxerman, Yi Fen Yen, Jayashree Kalpathy-Cramer, Andrew L. Beers, Mark Muzi, Ananth J. Madhuranthakam, Marco Pinho, Brian Johnson, and C. Chad Quarles

Analysis Of Postprocessing Steps For Residue Function Dependent Dynamic Susceptibility Contrast (Dsc)-Mri Biomarkers And Their Clinical Impact On Glioma Grading For Both 1.5 And 3T, Laura C. Bell, Ashley M. Stokes, and C. Chad Quarles

Neurofilaments in pre-symptomatic ALS and the impact of genotype., Michael Benatar, Joanne Wuu, Vittoria Lombardi, Andreas Jeromin, Robert Bowser, Peter M Andersen, and Andrea Malaspina

Highlights of the 13th International Hereditary Hemorrhagic Telangiectasia Scientific conference, Hyunwoo Choi, Miles B. Conrad, S. Paul Oh, Beth L. Roman, and Andrew J. White

Organized Social Activity, Physical Exercise, and the Risk of Insomnia Symptoms Among Community-Dwelling Older Adults, Yohannes W. Endeshaw and Wonsuk Yoo

Pazopanib may reduce bleeding in hereditary hemorrhagic telangiectasia, Marie E. Faughnan, James R. Gossage, Murali M. Chakinala, S. Paul Oh, Raj Kasthuri, Christopher C.W. Hughes, Justin P. McWilliams, Joseph G. Parambil, Nicholas Vozoris, Jill Donaldson, Gitanjali Paul, Pamela Berry, and Dennis L. Sprecher

Alpha6-Containing Nicotinic Acetylcholine Receptor Is A Highly Sensitive Target Of Alcohol, Fenfei Gao, Dejie Chen, Xiaokuang Ma, Sterling Sudweeks, Jordan T. Yorgason, Ming Gao, Dharshaun Turner, Jason Brek Eaton, J. Michael McIntosh, Ronald J. Lukas, Paul Whiteaker, Yongchang Chang, Scott C. Steffensen, and Jie Wu

Brain-Derived Neurotrophic Factor (Bdnf) And Trkb Hippocampal Gene Expression Are Putative Predictors Of Neuritic Plaque And Neurofibrillary Tangle Pathology, Stephen D. Ginsberg, Michael H. Malek-Ahmadi, Melissa J. Alldred, Yinghua Chen, Kewei Chen, Moses V. Chao, Scott E. Counts, and Elliott J. Mufson

Selective Decline Of Neurotrophin And Neurotrophin Receptor Genes Within Ca1 Pyramidal Neurons And Hippocampus Proper: Correlation With Cognitive Performance And Neuropathology In Mild Cognitive Impairment And Alzheimer'S Disease, Stephen D. Ginsberg, Michael H. Malek-Ahmadi, Melissa J. Alldred, Shaoli Che, Irina Elarova, Yinghua Chen, Freddy Jeanneteau, Thorsten M. Kranz, Moses V. Chao, Scott E. Counts, and Elliott J. Mufson

Biomechanical Evaluation Of Cervicothoracic Junction Fusion Constructs, Jakub Godzik, Jonathan F. Dalton, Eduardo Martinez-del-Campo, Anna G.U.S. Newcomb, Felix Dominguez, Phillip M. Reyes, Nicholas Theodore, Brian P. Kelly, and Neil R. Crawford

Supplemental Rods Are Needed To Maximally Reduce Rod Strain Across The Lumbosacral Junction With Tlif But Not Alif In Long Constructs, Jakub Godzik, Randall J. Hlubek, Anna G.U.S. Newcomb, Jennifer N. Lehrman, Bernardo de Andrada, S. Harrison Farber, Lawrence G. Lenke, Brian P. Kelly, and Jay D. Turner

Impact Of Connector Placement And Design On Bending Stiffness Of Spinal Constructs, Jakub Godzik, Nick Hool, Jonathan F. Dalton, Alexander C. Whiting, Anna G.U.S. Newcomb, Brian P. Kelly, and Neil R. Crawford

Tailoring selection of transforaminal interbody spacers based on biomechanical characteristics and surgical goals: evaluation of an expandable spacer., Jakub Godzik, Jennifer N Lehrman, Anna G U S Newcomb, Ram Kumar Menon, Alexander C Whiting, Brian P. Kelly, and Laura A Snyder

Exosome Release And Cargo In Down Syndrome, Eric D. Hamlett, Angela LaRosa, Elliott J. Mufson, Juan Fortea, Aurélie Ledreux, and Ann Charlotte Granholm

Iliac Screws May Not Be Necessary In Long-Segment Constructs With L5€“S1 Anterior Lumbar Interbody Fusion: Cadaveric Study Of Stability And Instrumentation Strain, Randall J. Hlubek, Jakub Godzik, Anna G.U.S. Newcomb, Jennifer N. Lehrman, Bernardo de Andrada, Michael A. Bohl, Samuel H. Farber, Brian P. Kelly, and Jay D. Turner

Translating Preclinical Mri Methods To Clinical Oncology, David A. Hormuth, Anna G. Sorace, John Virostko, Richard G. Abramson, Zaver M. Bhujwalla, Pedro Enriquez-Navas, Robert Gillies, John D. Hazle, Ralph P. Mason, C. Chad Quarles, Jared A. Weis, Jennifer G. Whisenant, Junzhong Xu, and Thomas E. Yankeelov

Accurate Patient-Specific Machine Learning Models Of Glioblastoma Invasion Using Transfer Learning, L. S. Hu, H. Yoon, J. M. Eschbacher, L. C. Baxter, A. C. Dueck, A. Nespodzany, K. A. Smith, P. Nakaji, Y. Xu, L. Wang, J. P. Karis, A. J. Hawkins-Daarud, K. W. Singleton, P. R. Jackson, B. J. Anderies, B. R. Bendok, R. S. Zimmerman, C. Quarles, A. B. Porter-Umphrey, M. M. Mrugala, A. Sharma, J. M. Hoxworth, M. G. Sattur, N. Sanai, P. E. Koulemberis, C. Krishna, J. R. Mitchell, T. Wu, N. L. Tran, K. R. Swanson, and J. Li

Maternal Choline Supplementation Alters Basal Forebrain Cholinergic Neuron Gene Expression In The Ts65Dn Mouse Model Of Down Syndrome, Christy M. Kelley, Stephen D. Ginsberg, Melissa J. Alldred, Barbara J. Strupp, and Elliott J. Mufson

Enhancing Natural Killer Cells Is Beneficial In Multiple Sclerosis €“ No, Qiang Liu and Fu Dong Shi

Hdac2 Dysregulation In The Nucleus Basalis Of Meynert During The Progression Of Alzheimer'S Disease, L. Mahady, M. Nadeem, M. Malek-Ahmadi, K. Chen, S. E. Perez, and E. J. Mufson

Stapled Egfr Peptide Reduces Inflammatory Breast Cancer And Inhibits Additional Her-Driven Models Of Cancer, Sabrina A. Maisel, Derrick Broka, Benjamin Atwell, Thomas Bunch, Robert Kupp, Shiv K. Singh, Shwetal Mehta, and Joyce Schroeder

Cerebral Amyloid Angiopathy And Neuritic Plaque Pathology Correlate With Cognitive Decline In Elderly Non-Demented Individuals, Michael Malek-Ahmadi, Kewei Chen, Sylvia E. Perez, and Elliott J. Mufson

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Glycolysis Upregulation Is Neuroprotective As A Compensatory Mechanism In Als, Ernesto Manzo, Ileana Lorenzini, Dianne Barrameda, Abigail G. O'Conner, Jordan M. Barrows, Alexander Starr, Tina Kovalik, Benjamin E. Rabichow, Erik M. Lehmkuhl, Dakotah D. Shreiner, Archi Joardar, Jean Charles Liévens, Robert Bowser, Rita Sattler, and Daniela C. Zarnescu

Disruption Of Met Receptor Tyrosine Kinase An Autism Risk Factor Impairs Developmental Synaptic Plasticity In The Hippocampus, Xiaokuang Ma, Ke Chen, Zhongming Lu, Mariel Piechowicz, Qiang Liu, Jie Wu, and Shenfeng Qiu

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Mechanisms Of Cannabinoid Cb 2 Receptor-Mediated Reduction Of Dopamine Neuronal Excitability In Mouse Ventral Tegmental Area, Zegang Ma, Fenfei Gao, Brett Larsen, Ming Gao, Zhihua Luo, Dejie Chen, Xiaokuang Ma, Shenfeng Qiu, Yu Zhou, Junxia Xie, Zheng Xiong Xi, and Jie Wu

Cocaine Potently Blocks Neuronal α3β4 Nicotinic Acetylcholine Receptors In Sh-Sy5Y Cells, Ze gang Ma, Nan Jiang, Yuan bing Huang, Xiao kuang Ma, Jason Brek Eaton, Ming Gao, Yong Chang, Ronald J. Lukas, Paul Whiteaker, Janet Neisewander, and Jie Wu

Lipid And Polymer Blended Polyester Nanoparticles Loaded With Adapalene For Activation Of Retinoid Signaling In The Cns Following Intravenous Administration, David X. Medina, Eugene P. Chung, Robert Bowser, and Rachael W. Sirianni

Adar2 Mislocalization And Widespread Rna Editing Aberrations In C9Orf72-Mediated Als/Ftd, Stephen Moore, Eric Alsop, Ileana Lorenzini, Alexander Starr, Benjamin E. Rabichow, Emily Mendez, Jennifer L. Levy, Camelia Burciu, Rebecca Reiman, Jeannie Chew, Veronique V. Belzil, Dennis W. Dickson, Janice Robertson, Kim A. Staats, Justin K. Ichida, Leonard Petrucelli, Kendall Van Keuren-Jensen, and Rita Sattler

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Nerve Growth Factor Pathobiology During The Progression Of Alzheimer's Disease, Elliott J. Mufson, Scott E. Counts, Stephen D. Ginsberg, Laura Mahady, Sylvia E. Perez, Stephen M. Massa, Frank M. Longo, and Milos D. Ikonomovic