The Barrow Neurological Institute is proud of its reputation as a medical research facility and is home to some of the most sophisticated research programs outside of an academic setting in the Southwestern United States. Researchers in the Barrow Neurosurgery Research Center are devoted to learning more about the causes of and treatments for a wide range of disorders, such as stroke, aneurysms, spinal cord injury, and hydrocephalus. Our research has led to treatments that are being used around the world. Within the Department are neurosurgeons who subspecialize in cerebrovascular and skull base, functional and stereotactic, pediatric, spine, tumor, and endovascular neurosurgery.

Physicians, scientists, and expert clinical staff come together with a commitment to developing new techniques for the prevention, diagnosis, treatment, and rehabilitation of neurological illnesses and injuries. The leadership of internationally respected physicians keeps Barrow at the forefront of neuroscience. The compassionate expertise of its extensive staff of nurses, technologists, therapists and support personnel is evident in every aspect of care provided.

Our mission is to advance the knowledge and practice of medicine in neuroscience through basic and clinical research, education of medical professionals, and innovation in clinical techniques and technology.

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Submissions from 2011

Arteriovenous Malformations and Associated Aneurysms, Kaith Almefty and Robert F. Spetzler

Cotton-Clipping Technique to Repair Intraoperative Aneurysm Neck Tear: A Technical Note, Daniel L. Barrow and Robert F. Spetzler

Brain arteriovenous malformation multiplicity predicts the diagnosis of hereditary hemorrhagic telangiectasia: quantitative assessment, Aditya Bharatha, Marie E. Faughnan, Helen Kim, Tony Pourmohamad, Timo Krings, Pinar Bayrak-Toydemir, Ludmila Pawlikowska, Charles E. McCulloch, Michael T. Lawton, Christopher F. Dowd, William L. Young, and Karel G. Terbrugge

Temporal stability of dysmorphic fusiform aneurysms of the intracranial internal carotid artery, Loic Boussel, Vitaliy Rayz, Alastair Martin, Michael Lawton, Randall Higashida, Wade S. Smith, William L. Young, and David Saloner

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Surgical management and outcome of schwannomas in the craniocervical region, Daniel D. Cavalcanti, Nikolay L. Martirosyan, Ketan Verma, Sam Safavi-Abbasi, Randall W. Porter, Nicholas Theodore, Volker K. Sonntag, Curtis A. Dickman, and Robert F. Spetzler

A Prospective Study of Nonfunctioning Pituitary Adenomas: Presentation Management and Clinical Outcome, Lukui Chen, William L. White, Robert F. Spetzler, and Bainan Xu

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Neurogenetics and clinical evidence for the putative activation of the brain reward circuitry by a neuroadaptagen: proposing an addiction candidate gene panel map, Thomas J. Chen, Kenneth Blum, Amanda L. Chen, Abdalla Bowirrat, William B. Downs, Margret A. Madigan, Roger L. Waite, John A. Bailey, Mallory Kerner, Swetha Yeldandi, Neil Majmundar, John Giordano, Siohban Morse, David Miller, Frank Fornari, and Eric R. Braverman

Pott Disease in a 13-Month-Old: Case Report, Giac Consigilieri, Udaya Kumar Kakarla, and Nicholas Theodore

Improving surgical outpatient efficiency through mobile phone text messaging, Mark A. Corrigan, Seamus M. McHugh, Rory K. Murphy, Paul Dhillon, Abid Shah, Immanuel Hennessy, Athar Sheikh, Elaine Lehane, and Arnold S. Hill

Classification schemes for arteriovenous malformations, Jason M. Davies, Helen Kim, William L. Young, and Michael T. Lawton

The contralateral transcingulate approach: operative technique and results with vascular lesions, Jason Davies, Rabih G. Tawk, and Michael T. Lawton

Development of an adhesive surgical ward round checklist; a technique to improve patient safety, P. Dhillon, R. K.J. Murphy, H. Ali, Z. Burukan, M. A. Corrigan, A. Sheikh, and A. D.K. Hill

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The 2011 Egyptian Revolution: a neurosurgical perspective, Mohamed El-Fiki and Gail Rosseau

Predictors of seizure freedom in the surgical treatment of supratentorial cavernous malformations, Dario J. Englot, Seunggu J. Han, Michael T. Lawton, and Edward F. Chang

Language and motor mapping during resection of brain arteriovenous malformations: Indications, feasibility, and utility, Andreu Gabarrós, William L. Young, Michael W. McDermott, and Michael T. Lawton

Transarterial Onyx Embolization of Sacral Chordoma: Case Report and Review of the Literature, Yin C. Hu, C. Benjamin Newman, Randall W. Porter, and Felipe C. Albuquerque

Craniofacial Approaches to Large Juvenile Angiofibromas: Clinical Article, M. Yashar S. Kalani, Maziyar A. Kalani, Samuel Kalb, Felipe C. Albuquerque, Cameron G. Mcdougall, Peter Nakaji, Robert F. Spetzler, Randall W. Porter, and Iman Feiz-Erfan

Tumoral Calcinosis Presenting as a Deformity of the Thoracic Spine: Case Report, M. Yashar S. Kalani, Nikolay L. Martirosyan, Andrew S. Little, Udaya Kumar Kakarla, and Nicholas Theodore

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Analysis of demographics, risk factors, clinical presentation, and surgical treatment modalities for the ossified posterior longitudinal ligament, Samuel Kalb, Nikolay L. Martirosyan, Luis Perez-Orribo, M Yashar Kalani, and Nicholas Theodore

Commentary on "Microporous Polysaccharide Hemospheres (MPH) for Cerebral Hemostasis: A Preliminary Report", James Kalyvas and Robert F. Spetzler

Critical roles of macrophages in the formation of intracranial aneurysm, Yasuhisa Kanematsu, Miyuki Kanematsu, Chie Kurihara, Yoshiteru Tada, Tsung Ling Tsou, Nico Van Rooijen, Michael T. Lawton, William L. Young, Elena I. Liang, Yoshitsugu Nuki, and Tomoki Hashimoto

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Stereotactic radiosurgery for chordoma: a report from the North American Gamma Knife Consortium, Hideyuki Kano, Fawaad O. Iqbal, Jason Sheehan, David Mathieu, Zachary A. Seymour, Ajay Niranjan, John C. Flickinger, Douglas Kondziolka, Bruce E. Pollock, Gail Rosseau, Penny K. Sneed, Michael W. McDermott, and L Dade Lunsford

Parafalcine and midline arteriovenous malformations: surgical strategy, techniques, and outcomes, Yong Bae Kim, William L. Young, and Michael T. Lawton

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Accurate state estimation from uncertain data and models: an application of data assimilation to mathematical models of human brain tumors, Eric J. Kostelich, Yang Kuang, Joshua M. McDaniel, Nina Z. Moore, Nikolay L. Martirosyan, and Mark C. Preul

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History and current state of neurosurgery at the Medical University of South Carolina, Vibhor Krishna, Yasmeen Rauf, Sunil Patel, Steve Glazier, Phanor Perot, and Dilantha B. Ellegala

Biomechanics of Thoracic Short Versus Long Fixation After 3-Column Injury: Laboratory Investigation, Bruno C.R. Lazaro, Fatih Ersay Deniz, Leonardo B.C. Brasiliense, Phillip M. Reyes, Anna G.U. Sawa, Nicholas Theodore, Volker K.H. Sonntag, and Neil R. Crawford

Prophylactic Antibiotic Trends in Transsphenoidal Surgery for Pituitary Lesions, Andrew S. Little and William L. White

Short-Duration Single-Agent Antibiotic Prophylaxis for Meningitis in Trans-Sphenoidal Surgery, Andrew S. Little and William L. White

MR imaging of partially thrombosed cerebral aneurysms: Characteristics and evolution, Alastair J. Martin, S. W. Hetts, W. P. Dillon, R. T. Higashida, V. Halbach, C. F. Dowd, M. T. Lawton, and D. Saloner

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Epidermal electronics, Nikolay Martirosyan and M Yashar Kalani

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Use of in vivo near-infrared laser confocal endomicroscopy with indocyanine green to detect the boundary of infiltrative tumor, Nikolay L. Martirosyan, Daniel D. Cavalcanti, Jennifer M. Eschbacher, Peter M. Delaney, Adrienne C. Scheck, Mohammed G. Abdelwahab, Peter Nakaji, Robert F. Spetzler, and Mark C. Preul

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Aplasia of the anterior arch of atlas associated with multiple congenital disorders: case report, Nikolay L. Martirosyan, Daniel D. Cavalcanti, M Yashar Kalani, Peter H. Maughan, and Nicholas Theodore

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Blood supply and vascular reactivity of the spinal cord under normal and pathological conditions, Nikolay L. Martirosyan, Jeanne S. Feuerstein, Nicholas Theodore, Daniel D. Cavalcanti, Robert F. Spetzler, and Mark C. Preul

Angiopoietin-like 4 (ANGPTL4) gene polymorphisms and risk of brain arteriovenous malformations, Bahar Mikhak, Shantel Weinsheimer, Ludmila Pawlikowska, Annie Poon, Pui-Yan Kwok, Michael T. Lawton, Yongmei Chen, Jonathan G. Zaroff, Stephen Sidney, Charles E. McCulloch, William L. Young, and Helen Kim

Surgical Approaches to Intramedullary Cavernous Malformations of the Spinal Cord, Alim P. Mitha, Jay D. Turner, and Robert F. Spetzler

The financial imperative of physicians to control demand of laboratory testing, R. K.J. Murphy, S. McHugh, N. O'Farrell, B. Dougherty, A. Sheikh, M. Corrigan, and A. D.K. Hill

Acute Transient Cortical Blindness Due to Seizure Following Cerebral Angiography, C. Benjamin Newman, Courtney M. Schusse, Yin C. Hu, Cameron G. McDougall, and Felipe C. Albuquerque

Endoscopic resection of intrathoracic tumors: experience with and long-term results for 26 patients., Francisco A Ponce, Brendan D Killory, Scott D Wait, Nicholas Theodore, and Curtis A Dickman

The most cited works in Parkinson's disease., Francisco A Ponce and Andres M Lozano

The Surgical Management of Parkinson's Disease, Francisco A. Ponce and Andres M. Lozano

Arteriovenous malformations: classification to cure., Francisco A Ponce and Robert F Spetzler

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Decompressive craniectomy: Technical note, T. M. Quinn, J. J. Taylor, J. A. Magarik, E. Vought, M. S. Kindy, and D. B. Ellegala

Flash fluorescence with indocyanine green videoangiography to identify the recipient artery for bypass with distal middle cerebral artery aneurysms: operative technique, Ana Rodríguez-Hernández and Michael T. Lawton

Aneurysms associated with non-moyamoya collateral arterial networks: report of three cases and review of literature, Ana Rodríguez-Hernández, Daniel C. Lu, Susanna Miric, and Michael T. Lawton

Segmental anatomy of cerebellar arteries: a proposed nomenclature. Laboratory investigation, Ana Rodríguez-Hernández, Albert L. Rhoton, and Michael T. Lawton

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Normal pressure hydrocephalus, Gail Rosseau

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Pituitary tumors and transsphenoidal surgery, Gail L. Rosseau

Intraoperative confocal microscopy for brain tumors: a feasibility analysis in humans., Nader Sanai, Jennifer M Eschbacher, Guido Hattendorf, Stephen W Coons, Mark C Preul, Kris A Smith, Peter Nakaji, and Robert F Spetzler

Intraoperative Confocal Microscopy in the Visualization of 5-Aminolevulinic Acid Fluorescence in Low-Grade Gliomas: Clinical Article, Nader Sanai, Laura A. Snyder, Norissa J. Honea, Stephen W. Coons, Jennifer M. Eschbacher, Kris A. Smith, and Robert F. Spetzler

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Neurosurgical treatment of trigeminal neuralgia, Sophia F. Shakur, Anita Bhansali, Ali Y. Mian, and Gail L. Rosseau

Large Hemangiopericytoma Associated With Arteriovenous Malformations and Dural Arteriovenous Fistulae, M. Yashar S. Kalani, Nikolay L. Martirosyan, Jennifer M. Eschbacher, Peter Nakaji, Felipe C. Albuquerque, and Robert F. Spetzler

Current Indications for Indocyanine Green Angiography, Laura A. Snyder and Robert F. Spetzler

Ossification of the Ligamentum Flavum (Olf): An Increasing Cause of Cervical Myelopathy, Volker K.H. Sonntag

A 3-Tier Classification of Cerebral Arteriovenous Malformations, Robert F. Spetzler and Francisco A. Ponce

The Evolution of Neurosurgical Instrumentation, Robert F. Spetzler and Rodney Samuelson

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Neurons in the Human Hippocampus and Amygdala Respond to Both Low- and High-Level Image Properties, Peter N. Steinmetz, Elaine Cabrales, Michael S. Wilson, Christopher P. Baker, Christopher K. Thorp, Kris A Smith, and David M. Treiman

Giant intracranial aneurysms: evolution of management in a contemporary surgical series, Michael E. Sughrue, David Saloner, Vitaliy L. Rayz, and Michael T. Lawton

Elevated BNP is associated with vasospasm-independent cerebral infarction following aneurysmal subarachnoid hemorrhage, Pam R. Taub, Jeremy D. Fields, Alan H.B. Wu, Jacob C. Miss, Michael T. Lawton, Wade S. Smith, William L. Young, Jonathan G. Zaroff, and Nerissa U. Ko

Progressive vertebral body osteolysis after cervical disc arthroplasty., Luis M Tumialán and Wayne M Gluf

Arthroscopic techniques in minimally invasive spine surgery: closure of the lumbar fascia: surgical technique., Luis M Tumialán, Ryan Ponton, and Anthony I Riccio

Supracerebellar infratentorial endoscopically controlled resection of pineal lesions: case series and operative technique., Timothy Uschold, Adib A Abla, David J Fusco, Ruth E Bristol, and Peter Nakaji

Gene expression profiling of blood in brain arteriovenous malformation patients, Shantel M. Weinsheimer, Huichun Xu, Achal S. Achrol, Boryana Stamova, Charles E. McCulloch, Ludmila Pawlikowska, Yingfang Tian, Nerissa U. Ko, Michael T. Lawton, Gary K. Steinberg, Steven D. Chang, Glen Jickling, Bradley P. Ander, Helen Kim, Frank R. Sharp, and William L. Young

Terminal ventriculostomy as an adjuvant treatment of complex syringomyelia: a case report and review of the literature., David A Wilson, David J Fusco, and Harold L Rekate

Delayed subarachnoid hemorrhage following failed odontoid screw fixation., David A Wilson, David J Fusco, and Nicholas Theodore

Submissions from 2010

Comparison of dural grafts in Chiari decompression surgery: Review of the literature., Adib A Abla, Timothy Link, David J Fusco, David A Wilson, and Volker K H Sonntag

Coiling Versus Clipping for Posterior Communicating Artery Aneurysms Associated With Oculomotor Nerve Palsy: Only Time Will Tell, Felipe C. Albuquerque

Stroke in the "Real World", Felipe C. Albuquerque

Long-term outcome in the repair of spinal cord perimedullary arteriovenous fistulas, L. Antonietti, S. A. Sheth, V. V. Halbach, R. T. Higashida, C. F. Dowd, M. T. Lawton, J. D. English, and Steven W. Hetts

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Initial audit of a basic and emergency neurosurgical training program in rural Tanzania, Jonah E. Attebery, Emanuel Mayegga, Robert G. Louis, Rachel Chard, Abednego Kinasha, and Dilantha B. Ellegala

The evolution of the treatment of traumatic cerebrovascular injury during wartime., Randy S Bell, Robert D Ecker, Meryl A Severson, John E Wanebo, Benjamin Crandall, and Rocco A Armonda

Wartime traumatic aneurysms: acute presentation, diagnosis, and multimodal treatment of 64 craniocervical arterial injuries., Randy S Bell, Alexander H Vo, Ryan Roberts, John E Wanebo, and Rocco A Armonda

Computed tomographic angiography in evaluation of superficial temporal to middle cerebral artery bypass., David A Besachio, Jordan I Ziegler, Timothy D Duncan, and John S Wanebo

Stabilization of the Atlantoaxial Joint With C1-C3 Lateral Mass Screw Constructs: Biomechanical Comparison With Standard Technique, Leonardo B.C. Brasiliense, Bruno C.R. Lazaro, Phillip M. Reyes, Douglas Fox, Volker K.H. Sonntag, and Neil R. Crawford

Anterolateral C1-C2 Transarticular Fixation for Atlantoaxial Arthrodesis: Landmarks Working Area and Angles of Approach, Daniel D. Cavalcanti, Abhishek Agrawal, Ulises Garcia-Gonzalez, Neil R. Crawford, Paulo L.M.S. Tavares, Nicholas Theodore, Volker K.H. Sonntag, and Mark C. Preul

The Anatomy of the Callosomarginal Artery: Applications to Microsurgery and Endovascular Surgery, Daniel D. Cavalcanti, Felipe C. Albuquerque, Benjamin F. Silva, Robert F. Spetzler, and Mark C. Preul

Supratentorial cavernous malformations in eloquent and deep locations: surgical approaches and outcomes. Clinical article, Edward F. Chang, Rodney A. Gabriel, Matthew B. Potts, Mitchel S. Berger, and Michael T. Lawton

Treatment of Distal Posterior Cerebral Artery Aneurysms: A Critical Appraisal of the Occipital Artery-To-Posterior Cerebral Artery Bypass, Steve W. Chang, Adib A. Abla, Udaya Kumar Kakarla, Eric Sauvageau, Shervin R. Dashti, Peter Nakaji, Joseph M. Zabramski, Felipe C. Albuquerque, Cameron G. McDougall, and Robert F. Spetzler

Four-Level Anterior Cervical Discectomy and Fusion With Plate Fixation: Radiographic and Clinical Results, Steve W. Chang, Udaya Kumar Kakarla, Peter H. Maughan, Jeff DeSanto, Douglas Fox, Nicholas Theodore, Curtis A. Dickman, Stephen M. Papadopoulos, and Volker K.H. Sonntag

Surgical technique of temporary arterial occlusion in the operative management of spinal hemangioblastomas, Aaron J. Clark, Daniel C. Lu, R. Mark Richardson, Tarik Tihan, Andrew T. Parsa, Dean Chou, Nicholas M. Barbaro, Sandeep Kunwar, Philip R. Weinstein, Michael T. Lawton, Mitchel S. Berger, and Michael W. McDermott

Commentary for Recurrent Intracranial Aneurysms After Successful Neck Clipping, Katharine Cronk and Robert F. Spetzler

Vertebral artery-posterior inferior cerebellar artery bypass using a radial artery graft for hemorrhagic dissecting vertebral artery aneurysms: surgical technique and report of 2 cases, Marcus Czabanka, Muhammad Ali, Peter Schmiedek, Peter Vajkoczy, and Michael T. Lawton

Supracerebellar Infratentorial Approach to Cavernous Malformations of the Brainstem: Surgical Variants and Clinical Experience With 45 Patients, Jean G. de Oliveira Santos, Gregory P. Lekovic, Sam Safavi-Abbasi, Cassius V. Reis, Ricardo A. Hanel, Randall W. Porter, Mark C. Preul, and Robert F. Spetzler

Sticking to the rules: Are you documenting your irish medical council registration number?, P. Dhillon, R. Murphy, Z. Burukan, H. Ali, M. Corrigan, A. Sheikh, and A. D.K. Hill

Anterior Selective Amygdalohippocampectomy: Technical Description and Microsurgical Anatomy., Eberval Gadelha Figueiredo, Pushpa Deshmukh, Peter Nakaji, Marcelo U. Crusius, Manoel J. Teixeira, Robert F. Spetzler, and Mark C. Preul

Neuroform Stent Assisted Aneurysm Treatment: Evolving Treatment Strategies Complications and Results of Long Term Follow-Up, David Fiorella, Felipe C. Albuquerque, H. Woo, P. A. Rasmussen, T. J. Masaryk, and C. G. McDougall

Evidence of endothelial progenitor cells in the human brain and spinal cord arteriovenous malformations, Peng Gao, Yongmei Chen, Michael T. Lawton, Nicholas M. Barbaro, Guo Yuan Yang, Hua Su, Feng Ling, and William L. Young

Occipitoatlantal Dislocation, Mark P. Garrett, Giacomo Consiglieri, Udaya Kumar Kakarla, Steve W. Chang, and Curtis A. Dickman

Transcranial Minimally Invasive Neurosurgery for Tumors, Mark P. Garrett, Giacomo Consiglieri, and Peter Nakaji

Formation of Painful Seroma and Edema After the Use of Recombinant Human Bone Morphogenetic Protein-2 in Posterolateral Lumbar Spine Fusions, Mark P. Garrett, Udaya Kumar Kakarla, Randall W. Porter, and Volker K.H. Sonntag

Use of Microscope-Integrated Near-Infrared Indocyanine Green Videoangiography in the Surgical Treatment of Spinal Dural Arteriovenous Fistulae, Ricardo A. Hanel, Peter Nakaji, and Robert F. Spetzler

No association between intraoperative hypothermia or supplemental protective drug and neurologic outcomes in patients undergoing temporary clipping during cerebral aneurysm surgery: Findings from the intraoperative hypothermia for aneurysm surgery trial, Bradley J. Hindman, Emine O. Bayman, Wolfgang K. Pfisterer, James C. Torner, Michael M. Todd, W. Clarke, K. Chaloner, P. Davis, M. Howard, D. Tranel, S. Anderson, J. Winn, M. Wichman, R. Peters, M. Hansen, D. Anderson, J. Lang, B. Yoo, H. Adams, G. Clifton, A. Gelb, C. Loftus, A. Schubert, D. Warner, W. Young, R. Frankowski, K. Kieburtz, D. Prough, L. Sternau, J. Marler, C. Moy, and B. Radziszewska

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Neurosurgery and global health: Going far and fast, together, Roger Hrtl and Dilantha B. Ellegala

Perfusion computed tomographic imaging and surgical selection with patients after poor-grade aneurysmal subarachnoid hemorrhage, Abel Po Hao Huang, Sandeep Arora, Max Wintermark, Nerrissa Ko, Yong Kwang Tu, and Michael T. Lawton

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The oculomotor nerve: microanatomical and endoscopic study, Giorgio Iaconetta, Matteo de Notaris, Luigi Maria Cavallo, Arnau Benet, Joaquim Enseñat, Madjid Samii, Enrique Ferrer, Alberto Prats-Galino, and Paolo Cappabianca

Pediatric Intracranial Aneurysms, Brian J. Jian, Steven W. Hetts, Michael T. Lawton, and Nalin Gupta

Endovascular treatment of medically refractory cerebral vasospasm following aneurysmal subarachnoid hemorrhage, P. Jun, N. U. Ko, J. D. English, C. F. Dowd, V. V. Halbach, R. T. Higashida, M. T. Lawton, and Steven W. Hetts

Microsurgical treatment of pediatric intracranial aneurysms: long-term angiographic and clinical outcomes., Udaya K Kakarla, Elisa J Beres, Francisco A Ponce, Steven W Chang, Vivek R Deshmukh, Nicholas C Bambakidis, Joseph M Zabramski, and Robert F Spetzler

Atlas Fractures, Udaya Kumar Kakarla, Steve W. Chang, Nicholas Theodore, and Volker K.H. Sonntag

Placement of Percutaneous Thoracic Pedicle Screws Using Neuronavigation, Udaya Kumar Kakarla, Andrew S. Little, Steve W. Chang, Volker K.H. Sonntag, and Nicholas Theodore

Gamma Knife surgery combined with resection for treatment of a single brain metastasis: preliminary results., M Yashar S Kalani, Aristotelis S Filippidis, Maziyar A Kalani, Nader Sanai, David Brachman, Heyoung L McBride, Andrew G Shetter, and Kris A Smith