The Barrow Neurological Institute is proud of its reputation as a medical research facility and is home to some of the most sophisticated research programs outside of an academic setting in the Southwestern United States. Researchers in the Barrow Neurosurgery Research Center are devoted to learning more about the causes of and treatments for a wide range of disorders, such as stroke, aneurysms, spinal cord injury, and hydrocephalus. Our research has led to treatments that are being used around the world. Within the Department are neurosurgeons who subspecialize in cerebrovascular and skull base, functional and stereotactic, pediatric, spine, tumor, and endovascular neurosurgery.
Physicians, scientists, and expert clinical staff come together with a commitment to developing new techniques for the prevention, diagnosis, treatment, and rehabilitation of neurological illnesses and injuries. The leadership of internationally respected physicians keeps Barrow at the forefront of neuroscience. The compassionate expertise of its extensive staff of nurses, technologists, therapists and support personnel is evident in every aspect of care provided.
Our mission is to advance the knowledge and practice of medicine in neuroscience through basic and clinical research, education of medical professionals, and innovation in clinical techniques and technology.
Submissions from 2007
Nonconvulsive Status Epilepticus in Patients Suffering Spontaneous Subarachnoid Hemorrhage, Andrew S. Little, John F. Kerrigan, Cameron G. McDougall, Joseph M. Zabramski, Felipe C. Albuquerque, Peter Nakaji, and Robert F. Spetzler
Anterior Motor Strip Displacement in a Boy With Right Frontal Gray Matter Heterotopia Undergoing Epilepsy Surgery, Andrew S. Little, Yu tze Ng, John F. Kerrigan, David M. Treiman, Evan Fram, and Harold L. Rekate
The role of neurosurgery in status epilepticus., Yu-Tze Ng, Ruth E Bristol, Dewi V Schrader, and Kris A Smith
Distal aneurysms of basilar perforating and circumferential arteries. Report of three cases, Rene O. Sanchez-Mejia and Michael T. Lawton
Complications of lumboperitoneal shunts, Vincent Y. Wang, Nicholas M. Barbaro, Michael T. Lawton, Lawrence Pitts, Sandeep Kunwar, Andrew T. Parsa, Nalin Gupta, and Michael W. McDermott
Postoperative hydrocephalus in patients undergoing decompressive hemicraniectomy for ischemic or hemorrhagic stroke., Allen Waziri, David J Fusco, Stephan A Mayer, Guy M McKhann, and E Sander Connolly
Interleukin-6 upregulates expression of KDR and stimulates proliferation of human cerebrovascular smooth muscle cells, Jianhua S. Yao, Wenwu Zhai, Yongfeng Fan, Michael T. Lawton, Nicholas M. Barbaro, William L. Young, and Guo Yuan Yang
Arteriovenous malformation, William L. Young, Pui-Yan Kwok, Ludmila Pawlikowska, Michael T. Lawton, Helen Kim, Pirro G. Hysi, and Douglas A. Marchuk
Submissions from 2006
Estimating the hemodynamic impact of interventional treatments of aneurysms: Numerical simulation with experimental validation: Technical case report, Gabriel Acevedo-Bolton, Liang Der Jou, Bradley P. Dispensa, Michael T. Lawton, Randall T. Higashida, Alastair J. Martin, William L. Young, and David Saloner
Long-Term Follow-Up of Giant Serpentine Mca Aneurysm Treated With EC-IC Bypass and Proximal Occlusion, S. Amin-Hanjani, P. R. Chen, Steve W. Chang, and Robert F. Spetzler
Prospective analysis of prevalence, distribution, and rate of recovery of left ventricular systolic dysfunction in patients with subarachnoid hemorrhage, Nader Banki, Alexander Kopelnik, Poyee Tung, Michael T. Lawton, Daryl Gress, Barbara Drew, Michael Dae, Elyse Foster, William Parmley, and Jonathan Zaroff
The Evolution of Endovascular Treatment for Intracranial Arteriovenous Malformations, Ruth E. Bristol, Felipe C. Albuquerque, and Cameron G. McDougall
Return to Contact Sports After Spinal Surgery, Mark G. Burnett and Volker K.H. Sonntag
Computed tomographic angiography for the evaluation of aneurysmal subarachnoid hemorrhage., Shaun D Carstairs, David A Tanen, Timothy D Duncan, Olaf B Nordling, John E Wanebo, Thomas R Paluska, Nicholas Theodore, and Robert H Riffenburgh
Outcome of Oculomotor Nerve Palsy From Posterior Communicating Artery Aneurysms: Comparison of Clipping and Coiling, Peng R. Chen, Sepideh Amin-Hanjani, Felipe C. Albuquerque, Cameron McDougall, Joseph M. Zabramski, and Robert F. Spetzler
MMP-9 expression is associated with leukocytic but not endothelial markers in brain arteriovenous malformations, Yongmei Chen, Yongfeng Fan, K. Y.Trudy Poon, Achal S. Achrol, Michael T. Lawton, Yiqian Zhu, Charles E. McCulloch, Tomoki Hashimoto, Chanhung Lee, Nicholas M. Barbaro, Andrew W. Bollen, Guo Yuan Yang, and William L. Young
Interleukin-6 involvement in brain arteriovenous malformations, Yongmei Chen, Ludmila Pawlikowska, Jianhua S. Yao, Fanxia Shen, Wenwu Zhai, Achal S. Achrol, Michael T. Lawton, Pui Yan Kwok, Guo Yuan Yang, and William L. Young
Posterior interhemispheric approach: Surgical technique, application to vascular lesions, and benefits of gravity retraction, John H. Chi and Michael T. Lawton
The "yo-yo" technique to prevent cerebrospinal fluid rhinorrhea after anterior clinoidectomy for proximal internal carotid artery aneurysms, John H. Chi, Michael Sughrue, Sandeep Kunwar, and Michael T. Lawton
Conus Medullaris Syndrome Without Lower-Extremity Involvement in L-1 Burst Fractures: Report of Four Cases, Dean Chou, Roger Hartl, and Volker K.H. Sonntag
Dynamic Characteristics of the Intact Fused and Prosthetic-Replaced Cervical Disk, Michael C. Dahl, Jeffrey P. Rouleau, Stephen M. Papadopoulos, David J. Nuckley, and Randal P. Ching
Long-Term Clinical and Angiographic Follow-Up of Unclippable Wrapped Intracranial Aneurysms, Vivek R. Deshmukh, Udaya Kumar Kakarla, Eberval Gadelha Figueiredo, Joseph M. Zabramski, and Robert F. Spetzler
Neuromonitoring in neurological critical care, Ian F. Dunn, Dilantha B. Ellegala, Zachary N. Litvack, and Dong H. Kim
Delayed re-opening of an STA-MCA bypass graft, I. F. Dunn, D. B. Ellegala, and A. L. Day
Neurosurgery at the crossroads: integrated multidisciplinary management of 449 patients with brain arteriovenous malformations, Rose Du, Michael W. McDermott, Christopher F. Dowd, William L. Young, and Michael T. Lawton
Durability of Aneurysm Embolization With Matrix Detachable Coils, David Fiorella, Felipe C. Albuquerque, and Cameron G. McDougall
Hypernatremia predicts adverse cardiovascular and neurological outcomes after SAH, Landis A. Fisher, Nerissa Ko, Jacob Miss, Poyee P. Tung, Alexander Kopelnik, Nader M. Banki, David Gardner, Wade S. Smith, Michael T. Lawton, and Jonathan G. Zaroff
Are Cavernous Sinus Hemangiomas and Cavernous Malformations Different Entities?, L. Fernando Gonzalez, Gregory P. Lekovic, Jennifer Eschbacher, Stephen Coons, Randall W. Porter, and Robert F. Spetzler
Contrast ultrasonographic assessment of cerebral perfusion in patients undergoing decompressive craniectomy for traumatic brain injury, Peter Heppner, Dilantha B. Ellegala, Marcel Durieux, John A. Jane, and Jonathan R. Lindner
Complications of Halo Fixation in the Elderly, Eric M. Horn, Nicholas Theodore, Iman Feiz-Erfan, Gregory P. Lekovic, Curtis A. Dickman, and Volker K.H. Sonntag
Co-occurrence of a cavernous malformation and contralateral moyamoya, G. A. Kerchner, W. Smith, M. T. Lawton, and V. Singh
Principles of cerebral oxygenation and blood flow in the neurological critical care unit, Dong H. Kim, Ian F. Dunn, Dilantha B. Ellegala, Jonathan F. Fox, and Dong H. Kim
Resolution of an Infectious Pseudoaneurysm in a Cervical Petrous Carotid Vein Bypass Graft After Covered Stent Placement: Case Report, Louis J. Kim, Felipe C. Albuquerque, Cameron G. McDougall, and Robert F. Spetzler
Postembolization Neurological Deficits in Cerebral Arteriovenous Malformations: Stratification by Arteriovenous Malformation Grade, Louis J. Kim, Felipe C. Albuquerque, Robert F. Spetzler, and Cameron G. McDougall
Predictors of left ventricular regional wall motion abnormalities after subarachnoid hemorrhage, Avinash Kothavale, Nader M. Banki, Alexander Kopelnik, Sirisha Yarlagadda, Michael T. Lawton, Nerissa Ko, Wade S. Smith, Barbara Drew, Elyse Foster, and Jonathan G. Zaroff
Double reimplantation technique to reconstruct arterial bifurcations with giant aneurysms, Michael T. Lawton and Alfredo Quiñones-Hinojosa
The supratonsillar approach to the inferior cerebellar peduncle: Anatomy, surgical technique, and clinical application to cavernous malformations, Michael T. Lawton, Alfredo Quiñones-Hinojosa, and Peter Jun
Intraoperative Rupture of Brainstem Cavernous Malformation: Case Report, Gregory P. Lekovic, L. Fernando Gonzalez, Vini G. Khurana, and Robert F. Spetzler
Apolipoprotein E epsilon 2 is associated with new hemorrhage risk in brain arteriovenous malformations, Ludmila Pawlikowska, K Y. Poon, Achal S. Achrol, Charles E. McCulloch, Connie Ha, Kristen Lum, Jonathan G. Zaroff, Nerissa U. Ko, S Claiborne Johnston, Stephen Sidney, Douglas A. Marchuk, Michael T. Lawton, Pui-Yan Kwok, and William L. Young
The extended retrosigmoid approach: An alternative to radical cranial base approaches for posterior fossa lesions, Alfredo Quiñones-Hinojosa, Edward F. Chang, and Michael T. Lawton
Hemorrhage of Cavernous Malformations During Pregnancy and in the Peripartum Period: Causal or Coincidence? Case Report and Review of the Literature, Sam Safavi-Abbasi, Iman Feiz-Erfan, Robert F. Spetzler, Louis Kim, Şeref Doǧan, Randall W. Porter, and Volker K.H. Sonntag
Pediatric intracranial aneurysms: Durability of treatment following microsurgical and endovascular management, Nader Sanai, Alfredo Quinones-Hinojosa, Nalin M. Gupta, Victor Perry, Peter P. Sun, Charles B. Wilson, and Michael T. Lawton
Superior outcomes in children compared with adults after microsurgical resection of brain arteriovenous malformations, René O. Sanchez-Mejia, Sravana K. Chennupati, Nalin Gupta, Heather Fullerton, William L. Young, and Michael T. Lawton
Sacral epithelioid angiosarcoma associated with a bleeding diathesis and spinal epidural hematoma: Case report, Rene O. Sanchez-Mejia, Steven G. Ojemann, Jeff Simko, Uzair B. Chaudhary, Jay Levy, and Michael T. Lawton
The Use of Computerized Image Guidance in Lumbar Disk Arthroplasty, Harvey E. Smith, Alexander R. Vaccaro, Philip S. Yuan, Stephen M. Papadopoulos, and Rick Sasso
Brain arteriovenous malformation in children, Sung Park Tae, Michael T. Lawton, René O. Sanchez-Mejia, Heather Fullerton, Nalin Gupta, and William L. Young
Endoscope-Assisted Microvascular Decompression for Trigeminal Neuralgia: Technical Case Report, Charles Teo, Peter Nakaji, and Ralph J. Mobbs
Pediatric intracranial aneurysms: A different perspective, Enrique C.G. Ventureyra, Nader Sanai, Nalin M. Gupta, and Michael T. Lawton
Management of cranial base chondrosarcomas., John E Wanebo, Ruth E Bristol, Randall W Porter, Stephen W Coons, and Robert F Spetzler
Surgical remission of pituitary adenomas confined to the neurohypophysis in Cushing's disease., Robert J Weil, Alexander O Vortmeyer, Lynnette K Nieman, Hetty L Devroom, John E Wanebo, and Edward H Oldfield
Cardiovascular predictors of in-patient mortality after subarachnoid hemorrhage, Sirisha Yarlagadda, Pam Rajendran, Jacob C. Miss, Nader M. Banki, Alexander Kopelnik, Alan H. Wu, Nerissa Ko, Adrian W. Gelb, Michael T. Lawton, Wade S. Smith, William L. Young, and Jonathan G. Zaroff
Adrenoceptor polymorphisms and the risk of cardiac injury and dysfunction after subarachnoid hemorrhage, Jonathan G. Zaroff, Ludmila Pawlikowska, Jacob C. Miss, Sirisha Yarlagadda, Connie Ha, Achal Achrol, Pui-Yan Kwok, Charles E. McCulloch, Michael T. Lawton, Nerissa Ko, Wade Smith, and William L. Young
Expression of hypoxia-inducible factor-1 and vascular endothelial growth factor in response to venous hypertension, Yiqian Zhu, Michael T. Lawton, Rose Du, Yamin Shwe, Yongmei Chen, Fanxia Shen, William L. Young, and Guo Yuan Yang
Submissions from 2005
Tumor necrosis factor-alpha-238G>A promoter polymorphism is associated with increased risk of new hemorrhage in the natural course of patients with brain arteriovenous malformations, Achal S. Achrol, Ludmila Pawlikowska, Charles E. McCulloch, K Y. Poon, Connie Ha, Jonathan G. Zaroff, S Claiborne Johnston, Chanhung Lee, Michael T. Lawton, Stephen Sidney, Douglas A. Marchuk, Pui-Yan Kwok, and William L. Young
Nonsaccular aneurysms of the azygos anterior cerebral artery, Kurtis I. Auguste, Marcus L. Ware, and Michael T. Lawton
Indications for Surgical Fusion of the Cervical and Lumbar Motion Segment, Nicholas C. Bambakidis, Iman Feiz-Erfan, Jeffrey D. Klopfenstein, and Volker K.H. Sonntag
Acute neurocardiogenic injury after subarachnoid hemorrhage, Nader M. Banki, Alexander Kopelnik, Michael W. Dae, Jacob Miss, Poyee Tung, Michael T. Lawton, Barbara J. Drew, Elyse Foster, Wade Smith, William W. Parmley, and Jonathan G. Zaroff
Adjacent Level Degeneration After Anterior Cervical Fusion: A Clinical Review, Juan C. Bartolomei, Nicholas Theodore, and Volker K.H. Sonntag
Supratentorial Arteriovenous Malformations, Richard E. Clatterbuck, Frank P.K. Hsu, and Robert F. Spetzler
Incidence of Superficial Sylvian Vein Compromise and Postoperative Effects on CT Imaging After Surgical Clipping of Middle Cerebral Artery Aneurysms, Bruce L. Denn, Robert C. Wallace, Joseph M. Zabramski, Alan M. Pitt, C. Roger Bird, and Robert F. Spetzler
Use of "Bonnet" Bypass With Radial Artery Interposition Graft in a Patient With Recurrent Cranial Base Carcinoma: Technical Report of Two Cases and Review of the Literature, Vivek R. Deshmukh, Randall W. Porter, and Robert F. Spetzler
Interobserver variability in grading of brain arteriovenous malformations using the Spetzler-Martin system, Rose Du, Christopher F. Dowd, S Clairborne Johnston, William L. Young, and Michael T. Lawton
Ruptured cerebral aneurysms, Dilantha B. Ellegala and Arthur L. Day
Characterization of genetically defined types of Charcot-Marie-Tooth neuropathies by using magnetic resonance neurography, Dilantha B. Ellegala, Stephen J. Monteith, David Haynor, Thomas D. Bird, Robert Goodkin, and Michel Kliot
The Radical Transbasal Approach for Resection of Anterior and Midline Skull Base Lesions, Iman Feiz-Erfan, Patrick P. Han, Robert F. Spetzler, Eric M. Horn, Jeffrey D. Klopfenstein, Randall W. Porter, Mauro A.T. Ferreira, Stephen P. Beals, Salvatore C. Lettieri, and Edward F. Joganic
Antiplatelet Therapy in Neuroendovascular Therapeutics, David Fiorella, Lucie Thiabolt, Felipe C. Albuquerque, Vivek R. Deshmukh, Cameron G. McDougall, and Peter A. Rasmussen
Long-term hemorrhage risk in children versus adults with brain arteriovenous malformations, Heather J. Fullerton, Achal S. Achrol, S. Claiborne Johnston, Charles E. McCulloch, Randall T. Higashida, Michael T. Lawton, Stephen Sidney, and William L. Young
De Novo Presentation of an Arteriovenous Malformation: Case Report and Review of the Literature, L. Fernando Gonzalez, Ruth E. Bristol, Randall W. Porter, and Robert F. Spetzler
Suppression of MMP-9 by doxycycline in brain arteriovenous malformations, Tomoki Hashimoto, Melissa M. Matsumoto, Jenny F. Li, Michael T. Lawton, and William L. Young
Coexpression of angiogenic factors in brain arteriovenous malformations, Tomoki Hashimoto, Yongqin Wu, Michael T. Lawton, Guo Yuan Yang, Nicholas M. Barbaro, and William L. Young
SCIWORA: An Antiquated Acronym, Eric M. Horn, Nicholas Theodore, and Volker K.H. Sonntag
Biomechanical Comparison of C1-2 Posterior Fixation Techniques., Jonathan S. Hott, James J. Lynch, Robert H. Chamberlain, Volker K.H. Sonntag, and Neil R. Crawford
Orbitozygomatic Approach to Basilar Apex Aneurysms, Frank P.K. Hsu, Richard E. Clatterbuck, and Robert F. Spetzler
Graft harvesting for revascularization in the head and neck., Terence E Johnson, John E Wanebo, Stephen W Bayles, and Charles Y Liu
Chlamydia pneumoniae burden in carotid arteries is associated with upregulation of plaque interleukin-6 and elevated C-reactive protein in serum, S Claiborne Johnston, Hui Zhang, Louis M. Messina, Michael T. Lawton, and Deborah Dean
Correlation between lumenal geometry changes and hemodynamics in fusiform intracranial aneurysms, Liang Der Jou, Gregory Wong, Brad Dispensa, Michael T. Lawton, Randall T. Higashida, William L. Young, and David Saloner
Age and aneurysm position predict patterns of left ventricular dysfunction after subarachnoid hemorrhage, Kiran Khush, Alexander Kopelnik, Poyee Tung, Nader Banki, Michael Dae, Michael Lawton, Wade Smith, Barbara Drew, Elyse Foster, and Jonathan Zaroff
Combined Surgical and Endovascular Treatment of a Recurrent A3-A3 Junction Aneurysm Unsuitable for Stand-Alone Clip Ligation or Coil Occlusion: Technical Note, Louis J. Kim, Felipe C. Albuquerque, Cameron McDougall, and Robert F. Spetzler
Prevalence and implications of diastolic dysfunction after subarachnoid hemorrhage, Alexander Kopelnik, Landis Fisher, Jacob C. Miss, Nader Banki, Poyee Tung, Michael T. Lawton, Nerissa Ko, Wade S. Smith, Barbara Drew, Elyse Foster, and Jonathan Zaroff
Far-Lateral Approach to the Craniocervical Junction, Giuseppe Lanzino, Sergio Paolini, and Robert F. Spetzler
Effect of the neurosurgeon's surgical experience on outcomes from intraoperative aneurysmal rupture, Michael T. Lawton and Rose Du
Effect of presenting hemorrhage on outcome after microsurgical resection of brain arteriovenous malformations, Michael T. Lawton, Rose Du, Mary Nelson Tran, Achal S. Achrol, Charles E. McCulloch, S. Claiborne Johnston, Nancy J. Quinnine, and William L. Young
Thrombotic intracranial aneurysms: Classification scheme and management strategies in 68 patients, Michael T. Lawton, Alfredo Quiñones-Hinojosa, Edward F. Chang, and Timothy Yu
A novel gene mutation (1292 deletion) in a Chinese family with cerebral cavernous malformations, Ying Mao, Yao Zhao, Liang-Fu Zhou, Chuan-Xin Huang, Xue-Fei Shou, Jia-Lei Gong, Michael T. Lawton, and Guo-Yuan Yang
Subarachnoid Hemorrhage Due to Isolated Spinal Artery Aneurysm in Four Patients, Manoj G. Massand, Robert C. Wallace, L. Fernando Gonzalez, Joseph M. Zabramski, and Robert F. Spetzler
Management of Arteriovenous Malformations: A Surgical Perspective, Peter Nakaji, Pankaj Gore, and Robert F. Spetzler
Indications for Surgical Treatment of Arteriovenous Malformations, Peter Nakaji and Robert F. Spetzler
Endoscopic-Assisted Microvascular Decompression of the Cranial Nerves: Operative Technique, Peter Nakaji and Charles Teo
The Bryan Cervical Disc System, Stephen M. Papadopoulos
Polymorphisms in transforming growth factor-beta-related genes ALK1 and ENG are associated with sporadic brain arteriovenous malformations, Ludmila Pawlikowska, Mary N. Tran, Achal S. Achrol, Connie Ha, Esteban Burchard, Shweta Choudhry, Jonathan Zaroff, Michael T. Lawton, Richard Castro, Charles E. McCulloch, Douglas Marchuk, Pui-Yan Kwok, and William L. Young
Revascularization with saphenous vein bypasses for complex intracranial aneurysms, Alfredo Quiñones-Hinojosa, Rose Du, and Michael T. Lawton
In situ bypass in the management of complex intracranial aneurysms: Technique application in 13 patients, Alfredo Quiñones-Hinojosa and Michael T. Lawton
Intraoperative motor mapping of the cerebral peduncle during resection of a midbrain cavernous malformation: Technical case report, Alfredo Quiñones-Hinojosa, Russ Lyon, Rose Du, and Michael T. Lawton
Use of a side branch in a saphenous vein interposition graft for high-flow extracranial-intracranial bypass procedures. Technical note., Dennis J Rivet, John E Wanebo, Gareth A Roberts, and Ralph G Dacey
Pioneers in the development of neurological surgery in Auckland, New Zealand: Robertson, Wrightson, and Mackenzie, Jason P. Sheehan, Jonas M. Sheehan, Dilantha B. Ellegala, and Christopher Furneaux
Microvascular Decompression After Gamma Knife Surgery for Trigeminal Neuralgia: Intraoperative Findings and Treatment Outcomes, Andrew G. Shetter, Joseph M. Zabramski, and Burton L. Speiser
Microsurgical Anatomy and Quantitative Analysis of the Transtemporal- Transchoroidal Fissure Approach to the Ambient Cistern, Rungsak Siwanuwatn, Pushpa Deshmukh, Joseph M. Zabramski, Mark C. Preul, and Robert F. Spetzler
Plasma B-type natriuretic peptide levels are associated with early cardiac dysfunction after subarachnoid hemorrhage, Poyee P. Tung, Elise Olmsted, Alexander Kopelnik, Nader M. Banki, Barbara J. Drew, Nerissa Ko, Michael T. Lawton, Wade Smith, Elyse Foster, William L. Young, and Jonathan G. Zaroff
Angiogenesis in the brain during development: the effects of vascular endothelial growth factor and angiopoietin-2 in an animal model, G Edward Vates, Tomoki Hashimoto, William L. Young, and Michael T. Lawton
The baromodulatory effect of gamma knife irradiation of the hypothalamus in the obese Zucker rat, David A. Vincent, Tord D. Alden, Toshifumi Kamiryo, Beatrice Lopez, Dilantha Ellegala, Jeffrey J. Laurent, Michael Butler, Mary Lee Vance, and Edward R. Laws