The Barrow Neurological Institute is proud of its reputation as a medical research facility and is home to some of the most sophisticated research programs outside of an academic setting in the Southwestern United States. Researchers in the Barrow Neurosurgery Research Center are devoted to learning more about the causes of and treatments for a wide range of disorders, such as stroke, aneurysms, spinal cord injury, and hydrocephalus. Our research has led to treatments that are being used around the world. Within the Department are neurosurgeons who subspecialize in cerebrovascular and skull base, functional and stereotactic, pediatric, spine, tumor, and endovascular neurosurgery.
Physicians, scientists, and expert clinical staff come together with a commitment to developing new techniques for the prevention, diagnosis, treatment, and rehabilitation of neurological illnesses and injuries. The leadership of internationally respected physicians keeps Barrow at the forefront of neuroscience. The compassionate expertise of its extensive staff of nurses, technologists, therapists and support personnel is evident in every aspect of care provided.
Our mission is to advance the knowledge and practice of medicine in neuroscience through basic and clinical research, education of medical professionals, and innovation in clinical techniques and technology.
Submissions from 2002
Proposed use of prophylactic decompressive craniectomy in poor-grade aneurysmal subarachnoid hemorrhage patients presenting with associated large Sylvian hematomas, Edward R. Smith, Bob S. Carter, Christopher S. Ogilvy, Steven L. Giannotta, Michael T. Lawton, J. Mocco, E. Sander Connolly, and Robert A. Solomon
Cavernous Malformations Presenting With Seizures: Therapeutic Options and Outcome, Kris A. Smith, Sam Javedan, Joseph M. Zabramski, David E. Blum, and Robert F. Spetzler
Stereotactic radiosurgery for pediatric intracranial arteriovenous malformations: The University of California at San Francisco experience, Matthew D. Smyth, Penny K. Sneed, Samuel F. Ciricillo, Michael S. Edwards, William M. Wara, David A. Larson, Michael T. Lawton, Philip H. Gutin, and Michael W. McDermott
Modified Classification of Spinal Cord Vascular Lesions, Robert F. Spetzler, Paul W. Detwiler, Howard A. Riina, and Randall W. Porter
N-butyl cyanoacrylate embolization of cerebral arteriovenous malformations: Results of a prospective, randomized, multi-center trial, Thomas A. Tomsick, Phillip Purdy, Michael Horowitz, Thomas Kopitnik, Duke Samson, Jacques Dion, Gregory Joseph, Robert Dawson, David Owens, Danial Barrow, John Barr, Stephen Powers, Kevin Cockroft, Brian Holmes, Maria Sumas, Robert Wallace, Thomas Masaryk, John Perl, Douglas Chyatte, John M. Tew, Harry Van Loveren, Mario Zuccarello, Michael Marks, Alexander Norbash, Gary Steinberg, Van Halbach, Randall Higashida, Christopher Dowd, Michael Lawton, Charles Wilson, Cameron McDougall, and Robert Spetzler
Cervicomedullary junction compression caused by vertebral artery dolichoectasia and requiring surgical treatment. Case report, Eroboghene E. Ubogu, Cheré M. Chase, Margaret A. Verrees, Andrew K. Metzger, and Osama O. Zaidat
Magnetic source imaging demonstrates altered cortical distribution of function in patients with arteriovenous malformations, G. Edward Vates, Michael T. Lawton, Charles B. Wilson, Michael W. McDermott, Van V. Halbach, Timothy P.L. Roberts, Howard A. Rowley, Juha Jääskeläinen, Juha Hernesniemi, Jyrki Mäkelä, Nobuhiro Mikuni, Nobuo Hashimoto, Shahram Partovi, Robert F. Spetzler, Richard E. Latchaw, Oliver Ganslandt, and Rudolf Fahlbusch
Bow hunter stroke caused by cervical disc herniation. Case report, G Edward Vates, Kevin C. Wang, David Bonovich, Christopher F. Dowd, and Michael T. Lawton
Magnetic resonance imaging/spectroscopy of an intraaxial epidermoid: Similarity to an abscess: Case illustration, Cornelia S. Von Koch, Geoffrey Young, Cynthia T. Chin, and Michael T. Lawton
Magnetic resonance imaging/spectroscopy of an intraaxial epidermoid: similarity to an abscess. Case illustration, Cornelia S. von Koch, Geoffrey Young, Cynthia T. Chin, and Michael T. Lawton
Supratentorial Cavernous Malformations, John E. Wanebo, Giuseppe Lanzino, Joseph M. Zabramski, and Robert F. Spetzler
Anesthetic management of deep hypothermic circulatory arrest for cerebral aneurysm clipping, William L. Young, Michael T. Lawton, Dhanesh K. Gupta, and Tomoki Hashimoto
Submissions from 2001
Vertebral Artery Revascularization, Felipe C. Albuquerque and Robert F. Spetzler
The tandem bypass: Subclavian artery-to-middle cerebral artery bypass with dacron and saphenous vein grafts. Technical case report, Kurtis I. Auguste, Alfredo Quiones-Hinojosa, and Michael T. Lawton
Biomechanical Effects of Progressive Anterior Cervical Decompression, Tzu Yung Chen, Neil R. Crawford, Volker K.H. Sonntag, and Curtis A. Dickman
Current multimodality management of infectious intracranial aneurysms, Jay Y. Chun, Wade Smith, V. Van Halbach, Randall T. Higashida, Charles B. Wilson, and Michael T. Lawton
Biomechanics of Grade I Degenerative Lumbar Spondylolisthesis. Part 1: In Vitro Model, N. R. Crawford, S. Cagli, Volker K.H. Sonntag, and C. A. Dickman
Cranioorbital fibrous dysplasia: with emphasis on visual impairment and current surgical management., A. S. Dumont, P. T. Boulos, J. A. Jane, D. B. Ellegala, S. A. Newman, and J. A. Jane
Acute spinal cord injury, part I: Pathophysiologic mechanisms, Randall J. Dumont, David O. Okonkwo, Subodh Verma, R. John Hurlbert, Paul T. Boulos, Dilantha B. Ellegala, and Aaron S. Dumont
Acute spinal cord injury, part II: Contemporary pharmacotherapy, Randall J. Dumont, Subodh Verma, David O. Okonkwo, R. John Hurlbert, Paul T. Boulos, Dilantha B. Ellegala, and Aaron S. Dumont
Assessment of Silent Embolism From Carotid Endarterectomy by Use of Diffusion-Weighted Imaging: Work in Progress, K. P.N. Forbes, Holly A. Shill, P. M. Britt, Joseph M. Zabramski, R. F. Spetzler, and J. E. Heiserman
Abnormal balance in the angiopoietin-tie2 system in human brain arteriovenous malformations, T Hashimoto, T Lam, N J. Boudreau, A W. Bollen, M T. Lawton, and W L. Young
Evidence of increased endothelial cell turnover in brain arteriovenous malformations, Tomoki Hashimoto, Ricardo Mesa-Tejada, Christopher M. Quick, Andrew W. Bollen, Shailendra Joshi, John Pile-Spellman, Michael T. Lawton, and William L. Young
C-reactive protein levels and viable Chlamydia pneumoniae in carotid artery atherosclerosis, S. Claiborne Johnston, Louis M. Messina, Warren S. Browner, Michael T. Lawton, Caroline Morris, and Deborah Dean
Intraoperative MR systems. Low-field approaches, J S. Lewin and A K. Metzger
Pituitary Abscess [3] (multiple letters), N. F. Maartens, D. B. Ellegala, M. B.S. Lopes, G. E. Vates, and C. B. Wilson
Optimizing brain tumor resection. Low-field interventional MR imaging, A K. Metzger and J S. Lewin
Quantification of cerebral perfusion with "real-time" contrast-enhanced ultrasound, Se Joong Rim, Howard Leong-Poi, Jonathan R. Lindner, Daniel Couture, Dilantha Ellegala, Holland Mason, Marcel Durieux, Neal F. Kassel, and Sanjiv Kaul
Spontaneous Intracraniai Hypotension Mimicking Aneurysmal Subarachnoid Hemorrhage, Wouter I. Schievink, Eelco F.M. Wijdicks, Fredric B. Meyer, and Volker K.H. Sonntag
Surgical Management of Foramen Magnum Tumors, Robert F. Spetzler and Jeffrey S. Herrn
Decision Making in Degenerative Cervical Spine Surgery, N. Theodore and Volker K.H. Sonntag
A neurocytoma and an associated lenticulostriate artery aneurysm presenting with intraventricular hemorrhage: case report, G E. Vates, K A. Arthur, S G. Ojemann, F Williams, and M T. Lawton
Conus perimedullary arteriovenous fistula with intracranial drainage: Case report, G. Edward Vates, Alfredo Quiñones-Hinojosa, Van V. Halbach, and Michael T. Lawton
Quantitative analysis of the transcondylar approach to the foramen magnum., John E Wanebo and M R Chicoine
Optimization of Gamma knife treatment planning via guided evolutionary simulated annealing., P Zhang, D Dean, A Metzger, and C Sibata
Transpetrosal Approaches, Geoffrey Zubay, Randall W. Porter, and Robert F. Spetzler
Submissions from 2000
Interposition Short Vein Grafts, P. W. Detwiler, Randall W. Porter, Joseph M. Zabramski, and Robert F. Spetzler
Endoscopic Spine Surgery, C. A. Dickman, P. W. Detweiler, and Randall W. Porter
The Role of Pedicle Screw Fixation for Lumbar Spinal Stabilization and Fusion, C. A. Dickman, P. W. Detwiler, and Randall W. Porter
Pediatric Cervical Spine Injuries: Report of 102 Cases and Review of the Literature, Mohammed A. Eleraky, Nicholas Theodore, Mark Adams, Harold L. Rekate, and Volker K.H. Sonntag
Intracranial Aneurysms and Arterial Hypertension: A Review and Hypothesis, Servet Inci and Robert F. Spetzler
Intraoperative magnetic resonance image guidance in neurosurgery., J S Lewin, A Metzger, and W R Selman
Endovascular treatment of cerebral artery aneurysms during pregnancy: Report of three cases, P. M. Meyers, V. V. Halbach, A. M. Malek, C. C. Phatouros, C. F. Dowd, M. T. Lawton, T. E. Lempert, and R. T. Higashida
Surgical Approaches to the Brain Stem, Randall W. Porter, Paul W. Detwiler, and Robert F. Spetzler
Surgical Technique for Resection Cavernous Malformations of the Brain Stem, Randall W. Porter, Paul W. Detwiler, and Robert F. Spetzler
Results of transsphenoidal surgery for Cushing's disease in patients with no histologically confirmed tumor, J. M. Sheehan, M. Beatriz Lopes, J. P. Sheehan, D. Ellegala, K. M. Webb, Jr Laws, and W. F. Chandler
Radiosurgery for Cushing's disease after failed transsphenoidal surgery, J. M. Sheehan, M. L. Vance, J. P. Sheehan, D. B. Ellegala, and Jr Laws
Fenestration of the posteroinferior cerebellar artery: Case report, P. V. Theodosopoulos and M. T. Lawton
Extreme Lateral Supracerebellar Infratentorial Approach to the Posterolateral Mesencephalon: Technique and Clinical Experience, A. Giancarlo Vishteh, Carlos A. David, Frederick F. Marciano, Ernesto Coscarella, and Robert F. Spetzler
Submissions from 1999
Long-Term Survival of a Patient With Invasive Cranial Base Rhinocerebral Mucormycosis Treated With Combined Endovascular Surgical and Medical Therapies: Case Report, Cargill H. Alleyne, A. Giancarlo Vishteh, Robert F. Spetzler, and Paul W. Detwiler
Late Angiographic Follow-Up Review of Surgically Treated Aneurysms, Carlos A. David, A. Giancarlo Vishteh, Robert F. Spetzler, Michael Lemole, Michael T. Lawton, and Shahram Partovi
Sporadic Unifocal Infantile Myofibromatosis Involving the Skull: Case Report, Pall W. Detwiler, Randall W. Porter, Stephen W. Coons, Robert F. Spetzler, Carlos A. Carrion, and Harold L. Rekate
Evaluating patients with vertebrobasilar transient ischemic attacks, J. Haase, I. B. Magnussen, C. S. Ogilvy, R. G. Ojemann, F. B. Meyer, D. O. Quest, M. T. Lawton, C. G. McDougall, R. F. Spetzler, D. Samson, A. Takahashi, T. Yoshimoto, J. I. Ausman, F. T. Charbel, G. Debrum, V. Aletich, and M. Dujovny
Subdural Hematoma From a Type I Spinal Arteriovenous Malformation: Case Report, Patrick P. Han, Nicholas Theodore, Randall W. Porter, Paul W. Detwiler, Michael T. Lawton, and Robert F. Spetzler
Ethmoidal dural arteriovenous fistulae: An assessment of surgical and endovascular management, Michael T. Lawton, Jay Chun, Charles B. Wilson, and Van V. Halbach
Surgical Strategies for Giant Intracranial Aneurysms, Michael T. Lawton and Robert F. Spetzler
Modulation of macrophage and microglial responses to axonal injury in the peripheral and central nervous systems, Daniel A. Lazar, Dilantha B. Ellegala, Anthony M. Avellino, Andrew T. Dailey, Kate Andrus, and Michel Kliot
Spinal dural arteriovenous fistula with an associated feeding artery aneurysm: Case report, Adel M. Malek, Van V. Halbach, Constantine C. Phatouros, Randall T. Higashida, Christopher F. Dowd, Scott Wachhorst, and Michael T. Lawton
CNS Resident Award. Malignant meningiomas frequently lose multiple chromosomal regions in addition to 22q: putative meningioma progression loci identified by comparative genomic hybridization, A K. Metzger, Y A. Minn, D Lieberman, A W. Bollen, C B. Wilson, and B G. Feuerstein
Multiple genetic aberrations including evidence of chromosome 11q13 rearrangement detected in pituitary adenomas by comparative genomic hybridization, A K. Metzger, G Mohapatra, Y A. Minn, A W. Bollen, K Lamborn, F M. Waldman, C B. Wilson, and B G. Feuerstein
Cavernous malformations of the brainstem: experience with 100 patients, R W. Porter, P W. Detwiler, R F. Spetzler, M T. Lawton, J J. Baskin, P T. Derksen, and J M. Zabramski
Pediatric Spine and Spinal Cord Trauma: State of the Art for the Third Millennium, Harold L. Rekate, Nicholas Theodore, Volker K.H. Sonntag, and Curtis A. Dickman
Intraoperative Spinal Angiography, Wouter I. Schievink, A. Giancarlo Vishteh, Cameron G. Mcdougall, and Robert F. Spetzler
Gliomas in rodent whisker barrel cortex: a new tumor model., E W Sherburn, John E Wanebo, P Kim, S K Song, M R Chicoine, and T A Woolsey
Neurological Surgery, Volker K.H. Sonntag, Paul W. Detwiler, and Randall W. Porter
Controversy in Operative Techniques for Cervical Spondylosis Discectomy: Autograft Versus Allograft Versus No Graft, A. Giancarlo Vishteh, J. J. Baskin, and Volker K.H. Sonntag
Submissions from 1998
Ossification of Posterior Longitudinal Ligament in the Cervical Spine: Clinical Manifestations and Surgical Treatment, S. Cagli, C. A. Dickman, and Volker K.H. Sonntag
Medulloblastoma Presenting With Tentorial "Dural-Tail" Sign: is the "Dural-Tail" Sign Specific for Meningioma?, Paul W. Detwiler, Jeffrey S. Henn, Randall W. Porter, Michael T. Lawton, William L. White, and Robert F. Spetzler
Vascular Decompression of a Vertebral Artery Loop Producing Cervical Radiculopathy, Paul W. Detwiler, Randall W. Porter, Timothy R. Harrington, Volker K.H. Sonntag, and Robert F. Spetzler
Return of Olfaction After Gross Total Resection of an Olfactory Groove Meningioma: Case Report, Mark Gerber, A. Giancarlo Vishteh, and Robert F. Spetzler
Hypothermic Circulatory Arrest in Neurovascular Surgery: Evolving Indications and Predictors of Patient Outcome, Michael T. Lawton, Peter A. Raudzens, Joseph M. Zabramski, and Robert F. Spetzler
Management of Posttraumatic Syringomyelia Using an Expansile Duraplasty, Allan D.O. Levi and Volker K.H. Sonntag
Brain Protection for Cerebral Aneurysm Surgery, W. I. Schievink and Joseph M. Zabramski
Surgical of Superficial Siderosis Associated With a Treatment Spinal Arteriovenous Malformation, Wouter I. Schievink, Paul J. Apostolides, and Robert F. Spetzler
Rupture of a Previously Documented Small Asymptomatic Intracranial Aneurysm in a Patient With Autosomal Dominant Polycystic Kidney Disease, Wouter I. Schievink, Virginia Prendergast, and Joseph M. Zabramski
Enhanced endogenous antioxidant activity and inhibition of cerebral vasospasm in rabbits by pretreatment with a nontoxic endotoxin analog, monophosphoryl lipid A., T Toyoda, A L Kwan, M Bavbek, N F Kassell, John E Wanebo, and K S Lee
Long-Term Graft Patency Rates and Clinical Outcomes After Revascularization for Symptomatic Traumatic Internal Carotid Artery Dissection, A. Giancarlo Vishteh, Frederick F. Marciano, Carlos A. David, Wouter I. Schievink, Joseph M. Zabramski, and Robert F. Spetzler
Thoracoscopic Approaches to the Thoracic Spine, M. Visocchi, R. Masferrer, Volker K.H. Sonntag, and C. A. Dickman
Systemic administration of the endothelin-A receptor antagonist TBC 11251 attenuates cerebral vasospasm after experimental subarachnoid hemorrhage: dose study and review of endothelin-based therapies in the literature on cerebral vasospasm., John E Wanebo, A S Arthur, H G Louis, K West, N F Kassell, K S Lee, and G A Helm
Orbitozygomatic Craniotomy: Technical Note, Joseph M. Zabramski, Talat Kiriş, Suresh K. Sankhla, Josep Cabiol, and Robert F. Spetzler
Submissions from 1997
Embolization and radiosurgery for AVMs, P J. Apostolides, M T. Lawton, K A. Smith, and R F. Spetzler
Reversed-Flow Saphenous Vein Grafts for Cerebral Revascularization: Technical Note, Carlos A. David, Joseph M. Zabramski, and Robert F. Spetzler
Foramen Magnum Meningiomas, C. A. David and Robert F. Spetzler
De Novo Formation of a Central Nervous System Cavernous Malformation: Implications for Predicting Risk of Hemorrhage. Case Report and Review of the Literature, Paul W. Detwiler, Randall W. Porter, Joseph M. Zabramski, and Robert F. Spetzler
Detection of delayed cerebral vasospasm, after rupture of intracranial aneurysms, by magnetic resonance angiography, P W. Detwiler, R Porter, M T. Lawton, and R F. Spetzler
Degenerative Lumbar Spinal Instability: Technical Aspects of Operative Treatment, D. G. Karahalios, P. J. Apostolides, and Volker K.H. Sonntag
Neurosurgery at the Barrow Neurological Institute, Shelley A. Kick, Volker K.H. Sonntag, and Robert F. Spetzler
Management of arteriovenous malformations: Part II, S Kobayashi, K Hongo, S N. Bhagwati, Z H. Rappaport, M T. Lawton, and R F. Spetzler
Management of arteriovenous malformations: Part II., S. Kobayashi, K. Hongo, S. N. Bhagwati, Z. H. Rappaport, M. T. Lawton, and R. F. Spetzler
Technical aspects and recent trends in the management of large and giant midbasilar artery aneurysms, Michael T. Lawton, C. Phillip Daspit, and Robert F. Spetzler
Juvenile Active Ossifying Fibroma: Report of Four Cases, Michael T. Lawton, Joseph E. Heiserman, Stephen W. Coons, Bruce D. Ragsdale, and Robert F. Spetzler
Redefined role of angiogenesis in the pathogenesis of dural arteriovenous malformations, Michael T. Lawton, Ronald Jacobowitz, and Robert F. Spetzler
Presigmoid approaches to skull base lesions, M T. Lawton, C P. Daspit, and R F. Spetzler
Treatment for Intracranial Dural Arteriovenous Malformations: A Meta- Analysis From the English Language Literature, Ceasar P. Lucas, Joseph M. Zabramski, Robert F. Spetzler, and Ronald Jacobowitz
Linkage of the Locus for Cerebral Cavernous Hemangiomas to Human Chromosome 7Q in Four Families of Mexican-American Descent, M. H. Polymeropoulos, O. Hurko, F. Hsu, J. Rubenstein, S. Basnet, K. Lane, H. Dietz, Robert F. Spetzler, and D. Rigamonti
Concurrent aneurysm rupture and thrombosis of high grade internal carotid artery stenosis: Report of two cases, Randall W. Porter, Michael T. Lawton, Mark G. Hamilton, and Robert F. Spetzler
Operative Approaches for Intractable Temporal Lobe Epilepsy, Kris A. Smith and Andrew G. Shetter
Discussion on Newly Diagnosed Rheumatoid With Lower Cranial Nerve Abnormalities, Volker K.H. Sonntag
Neurosurgical Spine Fellowships: the Phoenix Model, Volker K.H. Sonntag
Bone Flap Fixation: A New Technique, Robert F. Spetzler