The Barrow Neurological Institute is proud of its reputation as a medical research facility and is home to some of the most sophisticated research programs outside of an academic setting in the Southwestern United States. Researchers in the Barrow Neurosurgery Research Center are devoted to learning more about the causes of and treatments for a wide range of disorders, such as stroke, aneurysms, spinal cord injury, and hydrocephalus. Our research has led to treatments that are being used around the world. Within the Department are neurosurgeons who subspecialize in cerebrovascular and skull base, functional and stereotactic, pediatric, spine, tumor, and endovascular neurosurgery.

Physicians, scientists, and expert clinical staff come together with a commitment to developing new techniques for the prevention, diagnosis, treatment, and rehabilitation of neurological illnesses and injuries. The leadership of internationally respected physicians keeps Barrow at the forefront of neuroscience. The compassionate expertise of its extensive staff of nurses, technologists, therapists and support personnel is evident in every aspect of care provided.

Our mission is to advance the knowledge and practice of medicine in neuroscience through basic and clinical research, education of medical professionals, and innovation in clinical techniques and technology.

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Submissions from 1994

Efficacy of Endovascular Treatment of Meningiomas: Evaluation With Matched Samples, B. L. Dean, R. A. Flom, R. C. Wallace, M. H. Khayata, N. A. Obuchowski, J. A. Hodak, Joseph M. Zabramski, and Robert F. Spetzler

Cavernous Malformations of the Brain Stem: A Review of 139 Cases, J. A. Fritschi, H. J. Reulen, Robert F. Spetzler, and Joseph M. Zabramski

Repair of Vertebral Artery Injury During Anterior Cervical Decompression, John G. Golfinos, Curtis A. Dickman, Joseph M. Zabramski, Volker K.H. Sonntag, and Robert F. Spetzler

Transverse Atlantal Ligament Disruption Associated With Odontoid Fractures, Karl A. Greene, Curtis A. Dickman, Frederick F. Marciano, Janine Drabier, Burton P. Drayer, and Volker K.H. Sonntag

Cardiopulmonary Bypass Hypothermic Circulatory Arrest and Barbiturate Cerebral Protection for the Treatment of Giant Vertebrobasilar Aneurysms in Children, Karl A. Greene, Frederick F. Marciano, Mark G. Hamilton, James M. Herman, Harold L. Rekate, and Robert F. Spetzler

Cervical Corpectomy and Plate Fixation for Postlaminectomy Kyphosis, J. M. Herman and Volker K.H. Sonntag

Titanium Dural Clip Testing. Technical Note, D. I. Levy and Volker K.H. Sonntag

Delayed Postoperative Tethering of the Cervical Spinal Cord, Kris A. Smith and H. L. Rekate

Submissions from 1993

Surgical Resection of Intramedullary Spinal Cord Cavernous Malformations, J. A. Anson and Robert F. Spetzler

Endarterectomy of the Intradural Vertebral Artery Via the Far Lateral Approach, John A. Anson and Robert F. Spetzler

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A denaturing gradient gel electrophoresis assay for sensitive detection of p53 mutations, J S. Beck, A E. Kwitek, P H. Cogen, A K. Metzger, G M. Duyk, and V C. Sheffield

Giant Serpentine Middle Cerebral Artery Aneurysm Treated By Extracranial- Intracranial Bypass: Case Report, K. A. Greene, J. A. Anson, and Robert F. Spetzler

Self-Inflicted Orbital and Intracranial Injury With a Retained Foreign Body Associated With Psychotic Depression: Case Report and Review, Karl A. Greene, Curtis A. Dickman, Kris A. Smith, Eugene J. Kinder, and Joseph M. Zabramski

Intracranial Pressure Reduction By a Central Alpha-2 Adrenoreceptor Agonist After Subarachnoid Hemorrhage, John M. McCormick, Patrick W. McCormick, Joseph M. Zabramski, and Robert F. Spetzler

Restoration of useful hearing after microvascular decompression of the cochlear nerve, G L. Rosseau, P J. Jannetta, B Hirsch, M B. Møller, and A R. Møller

Malignant peripheral nerve sheath tumors. A clinicopathologic study of 28 cases., John E Wanebo, J M Malik, S R VandenBerg, H J Wanebo, N Driesen, and J A Persing

Improved Transdural Exposure and Temporary Occlusion of the Petrous Internal Carotid Artery for Cavernous Sinus Surgery: Technical Note, T. M. Wascher, Robert F. Spetzler, and Joseph M. Zabramski

Submissions from 1992

Timing relationships for secondary ischemia in rodents: the effect of venous obstruction., M F Angel, K R Knight, C G Mellow, John E Wanebo, L R Amiss, and R M Morgan

Involvement of multiple chromosome 17p loci in medulloblastoma tumorigenesis, P H. Cogen, L Daneshvar, A K. Metzger, G Duyk, M S. Edwards, and V C. Sheffield

Isolation and characterization of Y chromosome DNA probes., S B Farah, D C Gruenert, J A Lepercq, J Chueh, A Metzger, E L Sartorato, R V Lebo, and M S Golbus

Facet Fracture-Dislocation Injuries of the Cervical Spine, Mark N. Hadley, Brian C. Fitzpatrick, Volker K.H. Sonntag, and Carol M. Browner

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Tumour resection by stereotactic laser endoscopy, F Hor, M Desgeorges, and G L. Rosseau

Thromboendarterectomy of the Symptomatic Occluded Internal Carotid Artery, P. W. McCormick, Robert F. Spetzler, J. E. Bailes, Joseph M. Zabramski, and J. L. Frey

Current prognosis in fetal ventriculomegaly., G L Rosseau, D C McCullough, and A L Joseph

Relationship of Perfusion Pressure and Size to Risk of Hemorrhage From Arteriovenous Malformations, Robert F. Spetzler, R. W. Hargraves, P. W. McCormick, Joseph M. Zabramski, R. A. Flom, and R. S. Zimmerman

Caspar Plate Fixation for the Treatment of Complex Hangman's Fractures, Gerald F. Tuite, Stephen M. Papadopoulos, and Volker K.H. Sonntag

Submissions from 1991

Timing relationships for secondary ischemia in rodents: the effect of arteriovenous obstruction., M F Angel, K R Knight, M J Biavati, C G Mellow, John E Wanebo, L R Amiss, and R M Morgan

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Loss of heterozygosity for chromosome 22 DNA sequences in human meningioma, P H. Cogen, L Daneshvar, A M. Bowcock, A K. Metzger, and L L. Cavalli-Sforza

Failure of Transluminal Angioplasty in the Treatment of Myointimal Hyperplasia of the Internal Carotid Artery: Case Report, F. Culicchia, Robert F. Spetzler, and R. A. Flom

Combined Approach for Lesions Involving the Cerebellopontine Angle and Skull Base: Experience With 20 Cases - Preliminary Report, C. Phillip Daspit, Robert F. Spetzler, and Conrad T.e. Pappas

Pediatric Spinal Cord Injury Without Radiographic Abnormalities: Report of 26 Cases and Review of the Literature, Curtis A. Dickman, Joseph M. Zabramski, Mark N. Hadley, Harold L. Rekate, and Volker K. Volker

A new technique for explantation and in vitro cultivation of chicken embryos, J D. Dugan, M T. Lawton, B Glaser, and H Brem

Clivus chordoma: a report of 12 recent cases and review of the literature, J W. Harbour, M T. Lawton, G R. Criscuolo, M J. Holliday, D E. Mattox, and D M. Long

Pediatric Intracranial Aneurysms: Simple and Complex Cases, J. M. Herman, H. L. Rekate, and Robert F. Spetzler

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Identification of a germ-line mutation in the p53 gene in a patient with an intracranial ependymoma, A K. Metzger, V C. Sheffield, G Duyk, L Daneshvar, M S. Edwards, and P H. Cogen

Failed back surgery syndrome: 5-year follow-up after spinal cord stimulator implantation, R. B. North, M. G. Ewend, M. T. Lawton, D. H. Kidd, and S. Piantadosi

Spinal cord stimulation for chronic, intractable pain: Superiority of "multi-channel" devices, Richard B. North, Matthew G. Ewend, Michael T. Lawton, and Steven Piantadosi

Atlantoaxial Stabilization in Rheumatoid Arthritis, Stephen M. Papadopoulos, C. A. Dickman, and Volker K.H. Sonntag

Traumatic Atlantooccipital Dislocation With Survival, Stephen M. Papadopoulos, C. A. Dickman, Volker K.H. Sonntag, H. L. Rekate, and Robert F. Spetzler

Gd-DTPA-enhancement magnetic resonance imaging of the cavernous sinus., G Rosseau, A Mark, and D O Davis

Submissions from 1990

The dorsal rat flap: a discussion of the model and the salutary effect of cimetidine on flap survival., M F Angel, John E Wanebo, V Bardakjian, L R Amiss, and R F Morgan

Management Morbidity and Mortability of Poor-Grade Aneurysm Patients, J. E. Bailes, Robert F. Spetzler, M. N. Hadley, and H. Z. Baldwin

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Deletion mapping of the medulloblastoma locus on chromosome 17p, P H. Cogen, L Daneshvar, A K. Metzger, and M S. Edwards

Spinal Epidural Hematoma Associated With Epidural Anesthesia: Complications of Systemic Heparinization in Patients Receiving Peripheral Vascular Thrombolytic Therapy, C. A. Dickman, S. A. Shedd, R. F. Spetzler, A. G. Shetter, and Volker K.H. Sonntag

Submissions from 1989

Familial Cerebral Cavernous Malformations, Robert F. Spetzler

Submissions from 1988

The Association of Venous and Cavernous Malformations - Report of Four Cases and Discussion of the Pathophysiological Diagnostic and Therapeutic Implications, D. Rigamonti and Robert F. Spetzler

Surgical Management of Large AVMS, Robert F. Spetzler and Joseph M. Zabramski

Submissions from 1986

Incidental Subcortical Lesions Identified on Magnetic Resonance Imaging in the Elderly. I. Correlation With Age and Cerebrovascular Risk Factors, Issam A. Awad, Robert F. Spetzler, John A. Hodak, Catherine A. Awad, and Russell Carey

A controlled study of transitional day care for non-chronically-ill patients., I D Glick, L Fleming, N DeChillo, N Meyerkopf, C Jackson, D Muscara, and M Good-Ellis

Neurogenic antinatriuresis during development of acute cardiac tamponade, J L. Osborn and M T. Lawton

Submissions from 1984

Cortical Blood Flow During Extracranial-Intracranial Bypass Surgery, L. Philip Carter, Robert M. Crowell, Volker K.H. Sonntag, and Robert F. Spetzler

Submissions from 1983

Surgical Treatment of an Abscess in a Rathke's Cleft Cyst, Volker K.H. Sonntag, Kathern L. Plenge, Michael S. Balis, Peter A. Raudzens, John A. Hodak, Robert J. Clark, and John D. Waggener

Submissions from 1982

The far lateral transpontomedullary sulcus approach to pontine cavernous malformations: Technical report and surgical results, Adib A. Abla, Arnau Benet, and Michael T. Lawton

Twenty-Year Follow-Up of Flow Reversal and Revascularization for a Giant Serpentine Basilar Artery Aneurysm, M. Yashar S. Kalani, Joseph M. Zabramski, Peter Nakaji, and Robert F. Spetzler

Robotic Autopositioning of the Operating Microscope, Mark E. Oppenlander, Shakeel A. Chowdhry, Brandon Merkl, Guido M. Hattendorf, Peter Nakaji, and Robert F. Spetzler

Indocyanine Green Angiography in the Surgical Management of Cerebral Arteriovenous Malformations: Lessons Learned in 130 Consecutive Cases, Hasan A. Zaidi, Adib A. Abla, Peter Nakaji, Shakeel A. Chowdhry, Felipe C. Albuquerque, and Robert F. Spetzler