Ectomesenchymal Hamartoma (Benign "ectomesenchymoma") of the VIIIth Nerve: Case Report

Authors

Paul J. Apostolides
Robert F. Spetzler, Barrow Neurological InstituteFollow
Peter C. Johnson

Department

neurosurgery

Document Type

Article

Abstract

WE REPORT A previously undescribed hamartoma of the VIIIth nerve, consisting of adipose tissue, Schwann cells associated with myelinated nerve fibers, well-differentiated smooth and striated muscle fibers, and rare ganglion cells. The tumor was found in a 35-year-old Caucasian female who presented with right-sided hearing loss. The mass, which we designate an “ectomesenchymal” hamartoma, most likely developed from pluripotent neural crest cells (“ectomesenchyme”), which are capable of differentiating into a variety of neuroectodermal and mesenchymal cell types. The development of the neural crest, the concept of “ectomesenchyme,” and the histogenesis of this tumor are reviewed. Copyright © by the Congress of Neurological Surgeons.

Publication Date

1995

Publication Title

Neurosurgery

ISSN

0148-396X

Volume

37

Issue

6

First Page

1204

Last Page

1207

Digital Object Identifier (DOI)

10.1227/00006123-199512000-00022

Recommended Citation

Apostolides, Paul J.; Spetzler, Robert F.; and Johnson, Peter C., "Ectomesenchymal Hamartoma (Benign "ectomesenchymoma") of the VIIIth Nerve: Case Report" (1995). Neurosurgery. 140.
https://scholar.barrowneuro.org/neurosurgery/140