The Barrow Neurological Institute is proud of its reputation as a medical research facility and is home to some of the most sophisticated research programs outside of an academic setting in the Southwestern United States. Researchers in the Barrow Neurosurgery Research Center are devoted to learning more about the causes of and treatments for a wide range of disorders, such as stroke, aneurysms, spinal cord injury, and hydrocephalus. Our research has led to treatments that are being used around the world. Within the Department are neurosurgeons who subspecialize in cerebrovascular and skull base, functional and stereotactic, pediatric, spine, tumor, and endovascular neurosurgery.
Physicians, scientists, and expert clinical staff come together with a commitment to developing new techniques for the prevention, diagnosis, treatment, and rehabilitation of neurological illnesses and injuries. The leadership of internationally respected physicians keeps Barrow at the forefront of neuroscience. The compassionate expertise of its extensive staff of nurses, technologists, therapists and support personnel is evident in every aspect of care provided.
Our mission is to advance the knowledge and practice of medicine in neuroscience through basic and clinical research, education of medical professionals, and innovation in clinical techniques and technology.
Submissions from 2003
Management of Acute Cerebellar Infarction: One Institution's Experience, Antonino Raco, Emanuela Caroli, Alessandra Isidori, Tommaso Vangelista, Maurizio Salvati, Michael T. Lawton, Daniel L. Barrow, R. Loch Macdonald, and Christopher S. Ogilvy
Extensive experience with dural sinus thrombosis, Scott W. Soleau, Richard Schmidt, Steve Stevens, Anne Osborn, Joel D. MacDonald, J. Max Findlay, H. Hunt Batjer, Daniel L. Barrow, Michael T. Lawton, Ferdinando Buonanno, and Christopher S. Ogilvy
Honored Guest Presentation: the Neurosurgeon as Mentor and Student, Volker K.H. Sonntag
The natural history of hemangioblastomas of the central nervous system in patients with von Hippel-Lindau disease., John E Wanebo, Russell R Lonser, Gladys M Glenn, and Edward H Oldfield
Surgical management of brainstem hemangioblastomas in patients with von Hippel-Lindau disease., Robert J Weil, Russell R Lonser, Hetty L DeVroom, John E Wanebo, and Edward H Oldfield
Submissions from 2002
Physiology and Pathophysiology of Cortico-Basal Ganglia-Thalamocortical Loops: Theoretical and Practical Aspects, Konstantin V. Baev, Karl A. Greene, Frederick F. Marciano, Johan E.S. Samanta, Andrew G. Shetter, Kris A. Smith, Mark A. Stacy, and Robert F. Spetzler
Association between subarachnoid hemorrhage outcomes and number of cases treated at California hospitals, Naomi S. Bardach, Shoujun Zhao, Daryl R. Gress, Michael T. Lawton, and S Claiborne Johnston
Spontaneous thrombosis of a residual arteriovenous malformation in eloquent cortex after surgery: Case report, Bernard R. Bendok, Christopher C. Getch, Mir Jafer Ali, Todd Parish, H. Hunt Batjer, Michael T. Lawton, Robert A. Solomon, and Christopher S. Ogilvy
Blood use in cerebrovascular neurosurgery, Daniel E. Couture, Dilantha B. Ellegala, Aaron S. Dumont, Paul D. Mintz, and Neal F. Kassell
Surgical Management of Atypical Cavernous Malformations, Vivek Deshmukh, Felipe C. Albuquerque, and Robert F. Spetzler
Intracranial metastasis of a primary scalp angiosarcoma: Case illustration, Dilantha B. Ellegala, Christopher Kligora, Scott Vandenberg, Aaron Dumont, and Mark E. Shaffrey
Use of FloSeal hemostatic sealant in transsphenoidal pituitary surgery: Technical note, Dilantha B. Ellegala, Nicholas F. Maartens, Edward R. Laws, Marc R. Mayberg, Ivan S. Ciric, Kalmon D. Post, and William F. Chandler
Mathematical modeling of noise and discovery of genetic expression classes in gliomas, Hassan M. Fathallah-Shaykh, Mo Rigen, Li-Juan Zhao, Kanti Bansal, Bin He, Herbert H. Engelhard, Leonard Cerullo, Kelvin Von Roenn, Richard Byrne, Lorenzo Munoz, Gail L. Rosseau, Roberta Glick, Terry Lichtor, and Elia DiSavino
Diffusion-weighted magnetic resonance imaging in patients with subarachnoid hemorrhage, Hiromu Hadeishi, Akifumi Suzuki, Nobuyuki Yasui, Jun Hatazawa, Eku Shimosegawa, Issam A. Awad, Michael T. Lawton, Christopher S. Ogilvy, Sherwin E. Hua, and Daniele Rigamonti
Characteristics of brain arteriovenous malformations with coexisting aneurysms: a comparison of two referral centers, Alexander X. Halim, Vineeta Singh, S Claiborne Johnston, Randall T. Higashida, Christopher F. Dowd, Van V. Halbach, Michael T. Lawton, Daryl R. Gress, Charles E. McCulloch, and William L. Young
Interactive Stereoscopic Virtual Reality: A New Tool for Neurosurgical Education, Jeffrey S. Henn, G. Michael Lemole, Mauro A.T. Ferreira, L. Fernando Gonzalez, Mark Schornak, Mark C. Preul, and Robert F. Spetzler
Cooling abolishes neuronal network synchronization in rat hippocampal slices., Sam P Javedan, Robert S Fisher, Hans G Eder, Kris A Smith, and Jie Wu
Interactive use of cerebral angiography and magnetoencephalography in arteriovenous malformations: Technical note, Toshifumi Kamiryo, Joshua Cappell, Eugene Kronberg, Henry H. Woo, Jafar J. Jafar, Rodolfo R. Llinás, Peter K. Nelson, Duke S. Samson, Marc R. Mayberg, Daniel L. Barrow, Michael T. Lawton, Göran Edner, and Kaj Ericson
Microsurgical fenestration of the lamina terminalis reduces the incidence of shunt-dependent hydrocephalus after aneurysmal subarachnoid hemorrhage, Ricardo J. Komotar, Alessandro Olivi, Daniele Rigamonti, Rafael J. Tamargo, E. Sander Connolly, Daniel L. Barrow, Michael T. Lawton, and J. Max Findlay
Cerebral Revascularization Performed Using Posterior Inferior Cerebellar Artery-Posterior Inferior Cerebellar Artery Bypass: Report of Four Cases and Literature Review, G. Michael Lemole, Jeffrey Henn, Sam Javedan, Vivek Deshmukh, and Robert F. Spetzler
Serum von Willebrand factor, matrix metalloproteinase-9, and vascular endothelial growth factor levels predict the onset of cerebral vasospasm after aneurysmal subarachnoid hemorrhage, Matthew J. McGirt, John R. Lynch, Robert Blessing, David S. Warner, Allan H. Friedman, Daniel T. Laskowitz, Michael T. Lawton, Issam A. Awad, J. Max Findlay, and Robert M. Friedlander
The long-term significance of microscopic dural invasion in 354 patients with pituitary adenomas treated with transsphenoidal surgery, Björn P. Meij, Maria-Beatriz S. Lopes, Dilantha B. Ellegala, Tord D. Alden, and Edward R. Laws
Optic nerve arteriovenous malformation causing optic apoplexy: Case report, Yoshihiro Muragaki, Hiroshi Ujiie, Masayuki Ohno, Osami Kubo, Tomokatsu Hori, Michael T. Lawton, Gary K. Steinberg, and Marc P. Sindou
Cavernous Malformations: Genetics Molecular Biology and Familial Forms, Emiliano Passacantilli, Joseph M. Zabramski, Giuseppe Lanzino, and Robert F. Spetzler
Surgical Treatment of Brain Stem Cavernous Malformations, Randall Porter, Joseph M. Zabramski, Giuseppe Lanzino, Iman Feiz-Erfan, and Robert F. Spetzler
Gamma knife radiosurgery for trigeminal neuralgia associated with multiple sclerosis., C Leland Rogers, Andrew G Shetter, Francisco A Ponce, Jeffrey A Fiedler, Kris A Smith, and Burton L Speiser
Gamma knife radiosurgery for recurrent trigeminal neuralgia., Andrew G Shetter, C Leland Rogers, Francisco A Ponce, Jeffrey A Fiedler, Kris A Smith, and Burton L Speiser
Surgical salvage of microcatheter-induced aneurysm perforation during coil embolization, John G. Short, William F. Marx, Giuseppe Lanzino, Dilantha B. Ellegala, and Neil F. Kassell
Proposed use of prophylactic decompressive craniectomy in poor-grade aneurysmal subarachnoid hemorrhage patients presenting with associated large Sylvian hematomas, Edward R. Smith, Bob S. Carter, Christopher S. Ogilvy, Steven L. Giannotta, Michael T. Lawton, J. Mocco, E. Sander Connolly, and Robert A. Solomon
Cavernous Malformations Presenting With Seizures: Therapeutic Options and Outcome, Kris A. Smith, Sam Javedan, Joseph M. Zabramski, David E. Blum, and Robert F. Spetzler
Stereotactic radiosurgery for pediatric intracranial arteriovenous malformations: The University of California at San Francisco experience, Matthew D. Smyth, Penny K. Sneed, Samuel F. Ciricillo, Michael S. Edwards, William M. Wara, David A. Larson, Michael T. Lawton, Philip H. Gutin, and Michael W. McDermott
Modified Classification of Spinal Cord Vascular Lesions, Robert F. Spetzler, Paul W. Detwiler, Howard A. Riina, and Randall W. Porter
N-butyl cyanoacrylate embolization of cerebral arteriovenous malformations: Results of a prospective, randomized, multi-center trial, Thomas A. Tomsick, Phillip Purdy, Michael Horowitz, Thomas Kopitnik, Duke Samson, Jacques Dion, Gregory Joseph, Robert Dawson, David Owens, Danial Barrow, John Barr, Stephen Powers, Kevin Cockroft, Brian Holmes, Maria Sumas, Robert Wallace, Thomas Masaryk, John Perl, Douglas Chyatte, John M. Tew, Harry Van Loveren, Mario Zuccarello, Michael Marks, Alexander Norbash, Gary Steinberg, Van Halbach, Randall Higashida, Christopher Dowd, Michael Lawton, Charles Wilson, Cameron McDougall, and Robert Spetzler
Cervicomedullary junction compression caused by vertebral artery dolichoectasia and requiring surgical treatment. Case report, Eroboghene E. Ubogu, Cheré M. Chase, Margaret A. Verrees, Andrew K. Metzger, and Osama O. Zaidat
Magnetic source imaging demonstrates altered cortical distribution of function in patients with arteriovenous malformations, G. Edward Vates, Michael T. Lawton, Charles B. Wilson, Michael W. McDermott, Van V. Halbach, Timothy P.L. Roberts, Howard A. Rowley, Juha Jääskeläinen, Juha Hernesniemi, Jyrki Mäkelä, Nobuhiro Mikuni, Nobuo Hashimoto, Shahram Partovi, Robert F. Spetzler, Richard E. Latchaw, Oliver Ganslandt, and Rudolf Fahlbusch
Bow hunter stroke caused by cervical disc herniation. Case report, G Edward Vates, Kevin C. Wang, David Bonovich, Christopher F. Dowd, and Michael T. Lawton
Magnetic resonance imaging/spectroscopy of an intraaxial epidermoid: Similarity to an abscess: Case illustration, Cornelia S. Von Koch, Geoffrey Young, Cynthia T. Chin, and Michael T. Lawton
Magnetic resonance imaging/spectroscopy of an intraaxial epidermoid: similarity to an abscess. Case illustration, Cornelia S. von Koch, Geoffrey Young, Cynthia T. Chin, and Michael T. Lawton
Supratentorial Cavernous Malformations, John E. Wanebo, Giuseppe Lanzino, Joseph M. Zabramski, and Robert F. Spetzler
Anesthetic management of deep hypothermic circulatory arrest for cerebral aneurysm clipping, William L. Young, Michael T. Lawton, Dhanesh K. Gupta, and Tomoki Hashimoto
Submissions from 2001
Vertebral Artery Revascularization, Felipe C. Albuquerque and Robert F. Spetzler
The tandem bypass: Subclavian artery-to-middle cerebral artery bypass with dacron and saphenous vein grafts. Technical case report, Kurtis I. Auguste, Alfredo Quiones-Hinojosa, and Michael T. Lawton
Biomechanical Effects of Progressive Anterior Cervical Decompression, Tzu Yung Chen, Neil R. Crawford, Volker K.H. Sonntag, and Curtis A. Dickman
Current multimodality management of infectious intracranial aneurysms, Jay Y. Chun, Wade Smith, V. Van Halbach, Randall T. Higashida, Charles B. Wilson, and Michael T. Lawton
Biomechanics of Grade I Degenerative Lumbar Spondylolisthesis. Part 1: In Vitro Model, N. R. Crawford, S. Cagli, Volker K.H. Sonntag, and C. A. Dickman
Cranioorbital fibrous dysplasia: with emphasis on visual impairment and current surgical management., A. S. Dumont, P. T. Boulos, J. A. Jane, D. B. Ellegala, S. A. Newman, and J. A. Jane
Acute spinal cord injury, part I: Pathophysiologic mechanisms, Randall J. Dumont, David O. Okonkwo, Subodh Verma, R. John Hurlbert, Paul T. Boulos, Dilantha B. Ellegala, and Aaron S. Dumont
Acute spinal cord injury, part II: Contemporary pharmacotherapy, Randall J. Dumont, Subodh Verma, David O. Okonkwo, R. John Hurlbert, Paul T. Boulos, Dilantha B. Ellegala, and Aaron S. Dumont
Assessment of Silent Embolism From Carotid Endarterectomy by Use of Diffusion-Weighted Imaging: Work in Progress, K. P.N. Forbes, Holly A. Shill, P. M. Britt, Joseph M. Zabramski, R. F. Spetzler, and J. E. Heiserman
Abnormal balance in the angiopoietin-tie2 system in human brain arteriovenous malformations, T Hashimoto, T Lam, N J. Boudreau, A W. Bollen, M T. Lawton, and W L. Young
Evidence of increased endothelial cell turnover in brain arteriovenous malformations, Tomoki Hashimoto, Ricardo Mesa-Tejada, Christopher M. Quick, Andrew W. Bollen, Shailendra Joshi, John Pile-Spellman, Michael T. Lawton, and William L. Young
C-reactive protein levels and viable Chlamydia pneumoniae in carotid artery atherosclerosis, S. Claiborne Johnston, Louis M. Messina, Warren S. Browner, Michael T. Lawton, Caroline Morris, and Deborah Dean
Intraoperative MR systems. Low-field approaches, J S. Lewin and A K. Metzger
Pituitary Abscess [3] (multiple letters), N. F. Maartens, D. B. Ellegala, M. B.S. Lopes, G. E. Vates, and C. B. Wilson
Optimizing brain tumor resection. Low-field interventional MR imaging, A K. Metzger and J S. Lewin
Quantification of cerebral perfusion with "real-time" contrast-enhanced ultrasound, Se Joong Rim, Howard Leong-Poi, Jonathan R. Lindner, Daniel Couture, Dilantha Ellegala, Holland Mason, Marcel Durieux, Neal F. Kassel, and Sanjiv Kaul
Spontaneous Intracraniai Hypotension Mimicking Aneurysmal Subarachnoid Hemorrhage, Wouter I. Schievink, Eelco F.M. Wijdicks, Fredric B. Meyer, and Volker K.H. Sonntag
Surgical Management of Foramen Magnum Tumors, Robert F. Spetzler and Jeffrey S. Herrn
Decision Making in Degenerative Cervical Spine Surgery, N. Theodore and Volker K.H. Sonntag
A neurocytoma and an associated lenticulostriate artery aneurysm presenting with intraventricular hemorrhage: case report, G E. Vates, K A. Arthur, S G. Ojemann, F Williams, and M T. Lawton
Conus perimedullary arteriovenous fistula with intracranial drainage: Case report, G. Edward Vates, Alfredo Quiñones-Hinojosa, Van V. Halbach, and Michael T. Lawton
Quantitative analysis of the transcondylar approach to the foramen magnum., John E Wanebo and M R Chicoine
Optimization of Gamma knife treatment planning via guided evolutionary simulated annealing., P Zhang, D Dean, A Metzger, and C Sibata
Transpetrosal Approaches, Geoffrey Zubay, Randall W. Porter, and Robert F. Spetzler
Submissions from 2000
Interposition Short Vein Grafts, P. W. Detwiler, Randall W. Porter, Joseph M. Zabramski, and Robert F. Spetzler
Endoscopic Spine Surgery, C. A. Dickman, P. W. Detweiler, and Randall W. Porter
The Role of Pedicle Screw Fixation for Lumbar Spinal Stabilization and Fusion, C. A. Dickman, P. W. Detwiler, and Randall W. Porter
Pediatric Cervical Spine Injuries: Report of 102 Cases and Review of the Literature, Mohammed A. Eleraky, Nicholas Theodore, Mark Adams, Harold L. Rekate, and Volker K.H. Sonntag
Intracranial Aneurysms and Arterial Hypertension: A Review and Hypothesis, Servet Inci and Robert F. Spetzler
Intraoperative magnetic resonance image guidance in neurosurgery., J S Lewin, A Metzger, and W R Selman
Endovascular treatment of cerebral artery aneurysms during pregnancy: Report of three cases, P. M. Meyers, V. V. Halbach, A. M. Malek, C. C. Phatouros, C. F. Dowd, M. T. Lawton, T. E. Lempert, and R. T. Higashida
Surgical Approaches to the Brain Stem, Randall W. Porter, Paul W. Detwiler, and Robert F. Spetzler
Surgical Technique for Resection Cavernous Malformations of the Brain Stem, Randall W. Porter, Paul W. Detwiler, and Robert F. Spetzler
Results of transsphenoidal surgery for Cushing's disease in patients with no histologically confirmed tumor, J. M. Sheehan, M. Beatriz Lopes, J. P. Sheehan, D. Ellegala, K. M. Webb, Jr Laws, and W. F. Chandler
Radiosurgery for Cushing's disease after failed transsphenoidal surgery, J. M. Sheehan, M. L. Vance, J. P. Sheehan, D. B. Ellegala, and Jr Laws
Fenestration of the posteroinferior cerebellar artery: Case report, P. V. Theodosopoulos and M. T. Lawton
Extreme Lateral Supracerebellar Infratentorial Approach to the Posterolateral Mesencephalon: Technique and Clinical Experience, A. Giancarlo Vishteh, Carlos A. David, Frederick F. Marciano, Ernesto Coscarella, and Robert F. Spetzler
Submissions from 1999
Long-Term Survival of a Patient With Invasive Cranial Base Rhinocerebral Mucormycosis Treated With Combined Endovascular Surgical and Medical Therapies: Case Report, Cargill H. Alleyne, A. Giancarlo Vishteh, Robert F. Spetzler, and Paul W. Detwiler
Late Angiographic Follow-Up Review of Surgically Treated Aneurysms, Carlos A. David, A. Giancarlo Vishteh, Robert F. Spetzler, Michael Lemole, Michael T. Lawton, and Shahram Partovi
Sporadic Unifocal Infantile Myofibromatosis Involving the Skull: Case Report, Pall W. Detwiler, Randall W. Porter, Stephen W. Coons, Robert F. Spetzler, Carlos A. Carrion, and Harold L. Rekate
Evaluating patients with vertebrobasilar transient ischemic attacks, J. Haase, I. B. Magnussen, C. S. Ogilvy, R. G. Ojemann, F. B. Meyer, D. O. Quest, M. T. Lawton, C. G. McDougall, R. F. Spetzler, D. Samson, A. Takahashi, T. Yoshimoto, J. I. Ausman, F. T. Charbel, G. Debrum, V. Aletich, and M. Dujovny
Subdural Hematoma From a Type I Spinal Arteriovenous Malformation: Case Report, Patrick P. Han, Nicholas Theodore, Randall W. Porter, Paul W. Detwiler, Michael T. Lawton, and Robert F. Spetzler
Ethmoidal dural arteriovenous fistulae: An assessment of surgical and endovascular management, Michael T. Lawton, Jay Chun, Charles B. Wilson, and Van V. Halbach
Surgical Strategies for Giant Intracranial Aneurysms, Michael T. Lawton and Robert F. Spetzler
Modulation of macrophage and microglial responses to axonal injury in the peripheral and central nervous systems, Daniel A. Lazar, Dilantha B. Ellegala, Anthony M. Avellino, Andrew T. Dailey, Kate Andrus, and Michel Kliot
Spinal dural arteriovenous fistula with an associated feeding artery aneurysm: Case report, Adel M. Malek, Van V. Halbach, Constantine C. Phatouros, Randall T. Higashida, Christopher F. Dowd, Scott Wachhorst, and Michael T. Lawton
CNS Resident Award. Malignant meningiomas frequently lose multiple chromosomal regions in addition to 22q: putative meningioma progression loci identified by comparative genomic hybridization, A K. Metzger, Y A. Minn, D Lieberman, A W. Bollen, C B. Wilson, and B G. Feuerstein
Multiple genetic aberrations including evidence of chromosome 11q13 rearrangement detected in pituitary adenomas by comparative genomic hybridization, A K. Metzger, G Mohapatra, Y A. Minn, A W. Bollen, K Lamborn, F M. Waldman, C B. Wilson, and B G. Feuerstein
Cavernous malformations of the brainstem: experience with 100 patients, R W. Porter, P W. Detwiler, R F. Spetzler, M T. Lawton, J J. Baskin, P T. Derksen, and J M. Zabramski
Pediatric Spine and Spinal Cord Trauma: State of the Art for the Third Millennium, Harold L. Rekate, Nicholas Theodore, Volker K.H. Sonntag, and Curtis A. Dickman
Intraoperative Spinal Angiography, Wouter I. Schievink, A. Giancarlo Vishteh, Cameron G. Mcdougall, and Robert F. Spetzler
Gliomas in rodent whisker barrel cortex: a new tumor model., E W Sherburn, John E Wanebo, P Kim, S K Song, M R Chicoine, and T A Woolsey
Neurological Surgery, Volker K.H. Sonntag, Paul W. Detwiler, and Randall W. Porter
Controversy in Operative Techniques for Cervical Spondylosis Discectomy: Autograft Versus Allograft Versus No Graft, A. Giancarlo Vishteh, J. J. Baskin, and Volker K.H. Sonntag
Submissions from 1998
Ossification of Posterior Longitudinal Ligament in the Cervical Spine: Clinical Manifestations and Surgical Treatment, S. Cagli, C. A. Dickman, and Volker K.H. Sonntag
Medulloblastoma Presenting With Tentorial "Dural-Tail" Sign: is the "Dural-Tail" Sign Specific for Meningioma?, Paul W. Detwiler, Jeffrey S. Henn, Randall W. Porter, Michael T. Lawton, William L. White, and Robert F. Spetzler
Vascular Decompression of a Vertebral Artery Loop Producing Cervical Radiculopathy, Paul W. Detwiler, Randall W. Porter, Timothy R. Harrington, Volker K.H. Sonntag, and Robert F. Spetzler
Return of Olfaction After Gross Total Resection of an Olfactory Groove Meningioma: Case Report, Mark Gerber, A. Giancarlo Vishteh, and Robert F. Spetzler
Hypothermic Circulatory Arrest in Neurovascular Surgery: Evolving Indications and Predictors of Patient Outcome, Michael T. Lawton, Peter A. Raudzens, Joseph M. Zabramski, and Robert F. Spetzler
Management of Posttraumatic Syringomyelia Using an Expansile Duraplasty, Allan D.O. Levi and Volker K.H. Sonntag