The Barrow Neurological Institute is proud of its reputation as a medical research facility and is home to some of the most sophisticated research programs outside of an academic setting in the Southwestern United States. Researchers in the Barrow Neurosurgery Research Center are devoted to learning more about the causes of and treatments for a wide range of disorders, such as stroke, aneurysms, spinal cord injury, and hydrocephalus. Our research has led to treatments that are being used around the world. Within the Department are neurosurgeons who subspecialize in cerebrovascular and skull base, functional and stereotactic, pediatric, spine, tumor, and endovascular neurosurgery.
Physicians, scientists, and expert clinical staff come together with a commitment to developing new techniques for the prevention, diagnosis, treatment, and rehabilitation of neurological illnesses and injuries. The leadership of internationally respected physicians keeps Barrow at the forefront of neuroscience. The compassionate expertise of its extensive staff of nurses, technologists, therapists and support personnel is evident in every aspect of care provided.
Our mission is to advance the knowledge and practice of medicine in neuroscience through basic and clinical research, education of medical professionals, and innovation in clinical techniques and technology.
Submissions from 1997
Attenuation of cerebral vasospasm by systemic administration of an endothelin-A receptor antagonist, TBC 11251, in a rabbit model of subarachnoid hemorrhage., John E Wanebo, H G Louis, A S Arthur, J Zhou, N F Kassell, K S Lee, and G A Helm
Submissions from 1996
Intracranial chondroma arising from the cranial vault: CT and MR appearance, K Abdelhamid, L R. Camras, E M. Nijensohn, G L. Rosseau, and L J. Cerullo
Characteristics and Surgical Treatment of Dolichoectatic and Fusiform Aneurysms, John A. Anson, Michael T. Lawton, and Robert F. Spetzler
Threaded Steinmann Pin Fusion of the Craniovertebral Junction, Paul J. Apostolides, Curtis A. Dickman, John G. Golfinos, Stephen M. Papadopoulos, and Volker K.H. Sonntag
Intra-Aortic Balloon Pump Counterpulsation in the Management of Concomitant Cerebral Vasospasm and Cardiac Failure After Subarachnoid Hemorrhage: Technical Case Report, Paul J. Apostolides, Karl A. Greene, Joseph M. Zabramski, John W. Fitzgerald, and Robert F. Spetzler
Dorsal Laminectomy in the Adult Mouse: A Model for Nervous System Research, Dilantha B. Ellegala, J. Channing Tassone, Anthony M. Avellino, Cynthia A. Pekow, Michael L. Cunningham, and Michel Kliot
Titanium aneurysm clips: Part II--Seizure and electroencephalographic studies in implanted rabbits, R S. Fisher, T Ehsan, K Smith, M T. Lawton, W D. Bichard, and R F. Spetzler
Spinal epidural hematoma [6], D. Foo, M. T. Lawton, V. K.H. Sonntag, and C. A. Dickman
Transpetrosal and Combination Approaches to Skull Base Lesions, Michael T. Lawton, C. P. Daspit, and Robert F. Spetzler
The Contralateral Transcallosal Approach: Experience With 32 Patients, Michael T. Lawton, John G. Golfinos, and Robert F. Spetzler
Revascularization and aneurysm surgery: Current techniques, indications, and outcome, Michael T. Lawton, Mark G. Hamilton, Jacques J. Morcos, and Robert F. Spetzler
Titanium Aneurysm Clips: Part I - Mechanical Radiological and Biocompatibility Testing, Michael T. Lawton, James C. Ho, William D. Bichard, Stephen W. Coons, Joseph M. Zabramski, and Robert F. Spetzler
Internal Carotid Artery Sacrifice for Radical Resection of Skull Base Tumors, Michael T. Lawton and Robert F. Spetzler
Titanium aneurysm clips: Part III--Clinical application in 16 patients with subarachnoid hemorrhage, M T. Lawton, J E. Heiserman, V C. Prendergast, J M. Zabramski, and R F. Spetzler
The Anatomical Suitability of the C1-2 Complex for Transarticular Screw Fixation, Christopher G. Paramore, Curtis A. Dickman, and Volker K.H. Sonntag
Submissions from 1995
Ectomesenchymal Hamartoma (Benign "ectomesenchymoma") of the VIIIth Nerve: Case Report, Paul J. Apostolides, Robert F. Spetzler, and Peter C. Johnson
Differential macrophage responses in the peripheral and central nervous system during wallerian degeneration of axons., A M Avellino, D Hart, A T Dailey, M MacKinnon, D Ellegala, and M Kliot
Differential macrophage responses in the peripheral and central nervous system during wallerian degeneration of axons, Anthony M. Avellino, David Hart, Andrew T. Dailey, Michael Mackinnon, Dilantha Ellegala, and Michel Kliot
Novel Heuristics of Functional Neural Networks: Implications for Future Strategies in Functional Neurosurgery, Konstantin V. Baev, Karl A. Greene, Frederick F. Marciano, Andrew G. Shelter, Abraham N. Lieberman, and Robert F. Spetzler
Posterior Skull Base Transfacial Approaches, S. P. Beals, E. F. Joganic, M. G. Hamilton, and Robert F. Spetzler
A Gene Responsible for Cavernous Malformations of the Brain Maps to Chromosome 7Q, Jan Dubovsky, Joseph M. Zabramski, Janice Kurth, Robert F. Spetzler, Steven S. Rich, Harry T. Orr, and James L. Weber
Clinical Use of a Frameless Stereotactic Arm: Results of 325 Cases, J. G. Golfinos, Brian C. Fitzpatrick, L. R. Smith, and Robert F. Spetzler
Neurosurgery in 50 Years, Harold J. Hoffman and Robert F. Spetzler
Ruptured Giant Aneurysm of an Occluded Middle Cerebral Artery in a Severe-Grade Patient: Case Report, Gary E. Kraus, James M. Herman, Frederick F. Marciano, and Robert F. Spetzler
Multimodality Treatment of Deep Arteriovenous Malformations: Thalamus Basal Ganglia and Brain Stem, Michael T. Lawton, Mark G. Hamilton, and Robert F. Spetzler
Radical Resection of Anterior Skull Base Tumors, Michael T. Lawton, M. G. Hamilton, S. P. Beals, E. F. Joganic, and R. F. Spetzler
Surgical Management of Giant Intracranial Aneurysms: Experience With 171 Patients, Michael T. Lawton and Robert F. Spetzler
Surgical management of spinal epidural hematoma: Relationship between surgical timing and neurological outcome, M. T. Lawton, R. W. Porter, J. E. Heiserman, R. Jacobowitz, V. K.H. Sonntag, and C. A. Dickman
Advances in Spinal Instrumentation, C. G. Paramore and Volker K.H. Sonntag
Current challenges in management of cranial base meningiomas., G Rosseau and L Cerullo
Supratentorial-Infraoccipital Approach for Posteromedial Temporal Lobe Lesions, Kris A. Smith and Robert F. Spetzler
Is Fusion Indicated for Lumbar Spinal Disorders?, Volker K.H. Sonntag and Frederick F. Marciano
Submissions from 1994
Efficacy of Endovascular Treatment of Meningiomas: Evaluation With Matched Samples, B. L. Dean, R. A. Flom, R. C. Wallace, M. H. Khayata, N. A. Obuchowski, J. A. Hodak, Joseph M. Zabramski, and Robert F. Spetzler
Cavernous Malformations of the Brain Stem: A Review of 139 Cases, J. A. Fritschi, H. J. Reulen, Robert F. Spetzler, and Joseph M. Zabramski
Repair of Vertebral Artery Injury During Anterior Cervical Decompression, John G. Golfinos, Curtis A. Dickman, Joseph M. Zabramski, Volker K.H. Sonntag, and Robert F. Spetzler
Transverse Atlantal Ligament Disruption Associated With Odontoid Fractures, Karl A. Greene, Curtis A. Dickman, Frederick F. Marciano, Janine Drabier, Burton P. Drayer, and Volker K.H. Sonntag
Cardiopulmonary Bypass Hypothermic Circulatory Arrest and Barbiturate Cerebral Protection for the Treatment of Giant Vertebrobasilar Aneurysms in Children, Karl A. Greene, Frederick F. Marciano, Mark G. Hamilton, James M. Herman, Harold L. Rekate, and Robert F. Spetzler
Cervical Corpectomy and Plate Fixation for Postlaminectomy Kyphosis, J. M. Herman and Volker K.H. Sonntag
Titanium Dural Clip Testing. Technical Note, D. I. Levy and Volker K.H. Sonntag
Delayed Postoperative Tethering of the Cervical Spinal Cord, Kris A. Smith and H. L. Rekate
Submissions from 1993
Surgical Resection of Intramedullary Spinal Cord Cavernous Malformations, J. A. Anson and Robert F. Spetzler
Endarterectomy of the Intradural Vertebral Artery Via the Far Lateral Approach, John A. Anson and Robert F. Spetzler
A denaturing gradient gel electrophoresis assay for sensitive detection of p53 mutations, J S. Beck, A E. Kwitek, P H. Cogen, A K. Metzger, G M. Duyk, and V C. Sheffield
Giant Serpentine Middle Cerebral Artery Aneurysm Treated By Extracranial- Intracranial Bypass: Case Report, K. A. Greene, J. A. Anson, and Robert F. Spetzler
Self-Inflicted Orbital and Intracranial Injury With a Retained Foreign Body Associated With Psychotic Depression: Case Report and Review, Karl A. Greene, Curtis A. Dickman, Kris A. Smith, Eugene J. Kinder, and Joseph M. Zabramski
Intracranial Pressure Reduction By a Central Alpha-2 Adrenoreceptor Agonist After Subarachnoid Hemorrhage, John M. McCormick, Patrick W. McCormick, Joseph M. Zabramski, and Robert F. Spetzler
Restoration of useful hearing after microvascular decompression of the cochlear nerve, G L. Rosseau, P J. Jannetta, B Hirsch, M B. Møller, and A R. Møller
Malignant peripheral nerve sheath tumors. A clinicopathologic study of 28 cases., John E Wanebo, J M Malik, S R VandenBerg, H J Wanebo, N Driesen, and J A Persing
Improved Transdural Exposure and Temporary Occlusion of the Petrous Internal Carotid Artery for Cavernous Sinus Surgery: Technical Note, T. M. Wascher, Robert F. Spetzler, and Joseph M. Zabramski
Submissions from 1992
Timing relationships for secondary ischemia in rodents: the effect of venous obstruction., M F Angel, K R Knight, C G Mellow, John E Wanebo, L R Amiss, and R M Morgan
Involvement of multiple chromosome 17p loci in medulloblastoma tumorigenesis, P H. Cogen, L Daneshvar, A K. Metzger, G Duyk, M S. Edwards, and V C. Sheffield
Isolation and characterization of Y chromosome DNA probes., S B Farah, D C Gruenert, J A Lepercq, J Chueh, A Metzger, E L Sartorato, R V Lebo, and M S Golbus
Facet Fracture-Dislocation Injuries of the Cervical Spine, Mark N. Hadley, Brian C. Fitzpatrick, Volker K.H. Sonntag, and Carol M. Browner
Tumour resection by stereotactic laser endoscopy, F Hor, M Desgeorges, and G L. Rosseau
Thromboendarterectomy of the Symptomatic Occluded Internal Carotid Artery, P. W. McCormick, Robert F. Spetzler, J. E. Bailes, Joseph M. Zabramski, and J. L. Frey
Current prognosis in fetal ventriculomegaly., G L Rosseau, D C McCullough, and A L Joseph
Relationship of Perfusion Pressure and Size to Risk of Hemorrhage From Arteriovenous Malformations, Robert F. Spetzler, R. W. Hargraves, P. W. McCormick, Joseph M. Zabramski, R. A. Flom, and R. S. Zimmerman
Caspar Plate Fixation for the Treatment of Complex Hangman's Fractures, Gerald F. Tuite, Stephen M. Papadopoulos, and Volker K.H. Sonntag
Submissions from 1991
Timing relationships for secondary ischemia in rodents: the effect of arteriovenous obstruction., M F Angel, K R Knight, M J Biavati, C G Mellow, John E Wanebo, L R Amiss, and R M Morgan
Loss of heterozygosity for chromosome 22 DNA sequences in human meningioma, P H. Cogen, L Daneshvar, A M. Bowcock, A K. Metzger, and L L. Cavalli-Sforza
Failure of Transluminal Angioplasty in the Treatment of Myointimal Hyperplasia of the Internal Carotid Artery: Case Report, F. Culicchia, Robert F. Spetzler, and R. A. Flom
Combined Approach for Lesions Involving the Cerebellopontine Angle and Skull Base: Experience With 20 Cases - Preliminary Report, C. Phillip Daspit, Robert F. Spetzler, and Conrad T.e. Pappas
Pediatric Spinal Cord Injury Without Radiographic Abnormalities: Report of 26 Cases and Review of the Literature, Curtis A. Dickman, Joseph M. Zabramski, Mark N. Hadley, Harold L. Rekate, and Volker K. Volker
A new technique for explantation and in vitro cultivation of chicken embryos, J D. Dugan, M T. Lawton, B Glaser, and H Brem
Clivus chordoma: a report of 12 recent cases and review of the literature, J W. Harbour, M T. Lawton, G R. Criscuolo, M J. Holliday, D E. Mattox, and D M. Long
Pediatric Intracranial Aneurysms: Simple and Complex Cases, J. M. Herman, H. L. Rekate, and Robert F. Spetzler
Identification of a germ-line mutation in the p53 gene in a patient with an intracranial ependymoma, A K. Metzger, V C. Sheffield, G Duyk, L Daneshvar, M S. Edwards, and P H. Cogen
Failed back surgery syndrome: 5-year follow-up after spinal cord stimulator implantation, R. B. North, M. G. Ewend, M. T. Lawton, D. H. Kidd, and S. Piantadosi
Spinal cord stimulation for chronic, intractable pain: Superiority of "multi-channel" devices, Richard B. North, Matthew G. Ewend, Michael T. Lawton, and Steven Piantadosi
Atlantoaxial Stabilization in Rheumatoid Arthritis, Stephen M. Papadopoulos, C. A. Dickman, and Volker K.H. Sonntag
Traumatic Atlantooccipital Dislocation With Survival, Stephen M. Papadopoulos, C. A. Dickman, Volker K.H. Sonntag, H. L. Rekate, and Robert F. Spetzler
Gd-DTPA-enhancement magnetic resonance imaging of the cavernous sinus., G Rosseau, A Mark, and D O Davis
Submissions from 1990
The dorsal rat flap: a discussion of the model and the salutary effect of cimetidine on flap survival., M F Angel, John E Wanebo, V Bardakjian, L R Amiss, and R F Morgan
Management Morbidity and Mortability of Poor-Grade Aneurysm Patients, J. E. Bailes, Robert F. Spetzler, M. N. Hadley, and H. Z. Baldwin
Deletion mapping of the medulloblastoma locus on chromosome 17p, P H. Cogen, L Daneshvar, A K. Metzger, and M S. Edwards
Spinal Epidural Hematoma Associated With Epidural Anesthesia: Complications of Systemic Heparinization in Patients Receiving Peripheral Vascular Thrombolytic Therapy, C. A. Dickman, S. A. Shedd, R. F. Spetzler, A. G. Shetter, and Volker K.H. Sonntag
Submissions from 1989
Familial Cerebral Cavernous Malformations, Robert F. Spetzler
Submissions from 1988
The Association of Venous and Cavernous Malformations - Report of Four Cases and Discussion of the Pathophysiological Diagnostic and Therapeutic Implications, D. Rigamonti and Robert F. Spetzler
Surgical Management of Large AVMS, Robert F. Spetzler and Joseph M. Zabramski
Submissions from 1986
Incidental Subcortical Lesions Identified on Magnetic Resonance Imaging in the Elderly. I. Correlation With Age and Cerebrovascular Risk Factors, Issam A. Awad, Robert F. Spetzler, John A. Hodak, Catherine A. Awad, and Russell Carey
A controlled study of transitional day care for non-chronically-ill patients., I D Glick, L Fleming, N DeChillo, N Meyerkopf, C Jackson, D Muscara, and M Good-Ellis
Neurogenic antinatriuresis during development of acute cardiac tamponade, J L. Osborn and M T. Lawton
Submissions from 1984
Cortical Blood Flow During Extracranial-Intracranial Bypass Surgery, L. Philip Carter, Robert M. Crowell, Volker K.H. Sonntag, and Robert F. Spetzler
Submissions from 1983
Surgical Treatment of an Abscess in a Rathke's Cleft Cyst, Volker K.H. Sonntag, Kathern L. Plenge, Michael S. Balis, Peter A. Raudzens, John A. Hodak, Robert J. Clark, and John D. Waggener
Submissions from 1982
The far lateral transpontomedullary sulcus approach to pontine cavernous malformations: Technical report and surgical results, Adib A. Abla, Arnau Benet, and Michael T. Lawton
Twenty-Year Follow-Up of Flow Reversal and Revascularization for a Giant Serpentine Basilar Artery Aneurysm, M. Yashar S. Kalani, Joseph M. Zabramski, Peter Nakaji, and Robert F. Spetzler
Robotic Autopositioning of the Operating Microscope, Mark E. Oppenlander, Shakeel A. Chowdhry, Brandon Merkl, Guido M. Hattendorf, Peter Nakaji, and Robert F. Spetzler
Indocyanine Green Angiography in the Surgical Management of Cerebral Arteriovenous Malformations: Lessons Learned in 130 Consecutive Cases, Hasan A. Zaidi, Adib A. Abla, Peter Nakaji, Shakeel A. Chowdhry, Felipe C. Albuquerque, and Robert F. Spetzler