The Barrow Neurological Institute is proud of its reputation as a medical research facility and is home to some of the most sophisticated research programs outside of an academic setting in the Southwestern United States. Researchers in the Barrow Neurosurgery Research Center are devoted to learning more about the causes of and treatments for a wide range of disorders, such as stroke, aneurysms, spinal cord injury, and hydrocephalus. Our research has led to treatments that are being used around the world. Within the Department are neurosurgeons who subspecialize in cerebrovascular and skull base, functional and stereotactic, pediatric, spine, tumor, and endovascular neurosurgery.

Physicians, scientists, and expert clinical staff come together with a commitment to developing new techniques for the prevention, diagnosis, treatment, and rehabilitation of neurological illnesses and injuries. The leadership of internationally respected physicians keeps Barrow at the forefront of neuroscience. The compassionate expertise of its extensive staff of nurses, technologists, therapists and support personnel is evident in every aspect of care provided.

Our mission is to advance the knowledge and practice of medicine in neuroscience through basic and clinical research, education of medical professionals, and innovation in clinical techniques and technology.

Follow

Submissions from 2001

Conus perimedullary arteriovenous fistula with intracranial drainage: Case report, G. Edward Vates, Alfredo Quiñones-Hinojosa, Van V. Halbach, and Michael T. Lawton

Quantitative analysis of the transcondylar approach to the foramen magnum., John E Wanebo and M R Chicoine

Optimization of Gamma knife treatment planning via guided evolutionary simulated annealing., P Zhang, D Dean, A Metzger, and C Sibata

Transpetrosal Approaches, Geoffrey Zubay, Randall W. Porter, and Robert F. Spetzler

Submissions from 2000

Interposition Short Vein Grafts, P. W. Detwiler, Randall W. Porter, Joseph M. Zabramski, and Robert F. Spetzler

Endoscopic Spine Surgery, C. A. Dickman, P. W. Detweiler, and Randall W. Porter

The Role of Pedicle Screw Fixation for Lumbar Spinal Stabilization and Fusion, C. A. Dickman, P. W. Detwiler, and Randall W. Porter

Pediatric Cervical Spine Injuries: Report of 102 Cases and Review of the Literature, Mohammed A. Eleraky, Nicholas Theodore, Mark Adams, Harold L. Rekate, and Volker K.H. Sonntag

Intracranial Aneurysms and Arterial Hypertension: A Review and Hypothesis, Servet Inci and Robert F. Spetzler

Intraoperative magnetic resonance image guidance in neurosurgery., J S Lewin, A Metzger, and W R Selman

Endovascular treatment of cerebral artery aneurysms during pregnancy: Report of three cases, P. M. Meyers, V. V. Halbach, A. M. Malek, C. C. Phatouros, C. F. Dowd, M. T. Lawton, T. E. Lempert, and R. T. Higashida

Surgical Approaches to the Brain Stem, Randall W. Porter, Paul W. Detwiler, and Robert F. Spetzler

Surgical Technique for Resection Cavernous Malformations of the Brain Stem, Randall W. Porter, Paul W. Detwiler, and Robert F. Spetzler

Link

Results of transsphenoidal surgery for Cushing's disease in patients with no histologically confirmed tumor, J. M. Sheehan, M. Beatriz Lopes, J. P. Sheehan, D. Ellegala, K. M. Webb, Jr Laws, and W. F. Chandler

Link

Radiosurgery for Cushing's disease after failed transsphenoidal surgery, J. M. Sheehan, M. L. Vance, J. P. Sheehan, D. B. Ellegala, and Jr Laws

Fenestration of the posteroinferior cerebellar artery: Case report, P. V. Theodosopoulos and M. T. Lawton

Extreme Lateral Supracerebellar Infratentorial Approach to the Posterolateral Mesencephalon: Technique and Clinical Experience, A. Giancarlo Vishteh, Carlos A. David, Frederick F. Marciano, Ernesto Coscarella, and Robert F. Spetzler

Submissions from 1999

Long-Term Survival of a Patient With Invasive Cranial Base Rhinocerebral Mucormycosis Treated With Combined Endovascular Surgical and Medical Therapies: Case Report, Cargill H. Alleyne, A. Giancarlo Vishteh, Robert F. Spetzler, and Paul W. Detwiler

Late Angiographic Follow-Up Review of Surgically Treated Aneurysms, Carlos A. David, A. Giancarlo Vishteh, Robert F. Spetzler, Michael Lemole, Michael T. Lawton, and Shahram Partovi

Sporadic Unifocal Infantile Myofibromatosis Involving the Skull: Case Report, Pall W. Detwiler, Randall W. Porter, Stephen W. Coons, Robert F. Spetzler, Carlos A. Carrion, and Harold L. Rekate

Evaluating patients with vertebrobasilar transient ischemic attacks, J. Haase, I. B. Magnussen, C. S. Ogilvy, R. G. Ojemann, F. B. Meyer, D. O. Quest, M. T. Lawton, C. G. McDougall, R. F. Spetzler, D. Samson, A. Takahashi, T. Yoshimoto, J. I. Ausman, F. T. Charbel, G. Debrum, V. Aletich, and M. Dujovny

Subdural Hematoma From a Type I Spinal Arteriovenous Malformation: Case Report, Patrick P. Han, Nicholas Theodore, Randall W. Porter, Paul W. Detwiler, Michael T. Lawton, and Robert F. Spetzler

Ethmoidal dural arteriovenous fistulae: An assessment of surgical and endovascular management, Michael T. Lawton, Jay Chun, Charles B. Wilson, and Van V. Halbach

Surgical Strategies for Giant Intracranial Aneurysms, Michael T. Lawton and Robert F. Spetzler

Link

Modulation of macrophage and microglial responses to axonal injury in the peripheral and central nervous systems, Daniel A. Lazar, Dilantha B. Ellegala, Anthony M. Avellino, Andrew T. Dailey, Kate Andrus, and Michel Kliot

Spinal dural arteriovenous fistula with an associated feeding artery aneurysm: Case report, Adel M. Malek, Van V. Halbach, Constantine C. Phatouros, Randall T. Higashida, Christopher F. Dowd, Scott Wachhorst, and Michael T. Lawton

CNS Resident Award. Malignant meningiomas frequently lose multiple chromosomal regions in addition to 22q: putative meningioma progression loci identified by comparative genomic hybridization, A K. Metzger, Y A. Minn, D Lieberman, A W. Bollen, C B. Wilson, and B G. Feuerstein

Link

Multiple genetic aberrations including evidence of chromosome 11q13 rearrangement detected in pituitary adenomas by comparative genomic hybridization, A K. Metzger, G Mohapatra, Y A. Minn, A W. Bollen, K Lamborn, F M. Waldman, C B. Wilson, and B G. Feuerstein

Cavernous malformations of the brainstem: experience with 100 patients, R W. Porter, P W. Detwiler, R F. Spetzler, M T. Lawton, J J. Baskin, P T. Derksen, and J M. Zabramski

Pediatric Spine and Spinal Cord Trauma: State of the Art for the Third Millennium, Harold L. Rekate, Nicholas Theodore, Volker K.H. Sonntag, and Curtis A. Dickman

Intraoperative Spinal Angiography, Wouter I. Schievink, A. Giancarlo Vishteh, Cameron G. Mcdougall, and Robert F. Spetzler

Gliomas in rodent whisker barrel cortex: a new tumor model., E W Sherburn, John E Wanebo, P Kim, S K Song, M R Chicoine, and T A Woolsey

Neurological Surgery, Volker K.H. Sonntag, Paul W. Detwiler, and Randall W. Porter

Controversy in Operative Techniques for Cervical Spondylosis Discectomy: Autograft Versus Allograft Versus No Graft, A. Giancarlo Vishteh, J. J. Baskin, and Volker K.H. Sonntag

Submissions from 1998

Ossification of Posterior Longitudinal Ligament in the Cervical Spine: Clinical Manifestations and Surgical Treatment, S. Cagli, C. A. Dickman, and Volker K.H. Sonntag

Medulloblastoma Presenting With Tentorial "Dural-Tail" Sign: is the "Dural-Tail" Sign Specific for Meningioma?, Paul W. Detwiler, Jeffrey S. Henn, Randall W. Porter, Michael T. Lawton, William L. White, and Robert F. Spetzler

Vascular Decompression of a Vertebral Artery Loop Producing Cervical Radiculopathy, Paul W. Detwiler, Randall W. Porter, Timothy R. Harrington, Volker K.H. Sonntag, and Robert F. Spetzler

Return of Olfaction After Gross Total Resection of an Olfactory Groove Meningioma: Case Report, Mark Gerber, A. Giancarlo Vishteh, and Robert F. Spetzler

Hypothermic Circulatory Arrest in Neurovascular Surgery: Evolving Indications and Predictors of Patient Outcome, Michael T. Lawton, Peter A. Raudzens, Joseph M. Zabramski, and Robert F. Spetzler

Management of Posttraumatic Syringomyelia Using an Expansile Duraplasty, Allan D.O. Levi and Volker K.H. Sonntag

Brain Protection for Cerebral Aneurysm Surgery, W. I. Schievink and Joseph M. Zabramski

Surgical of Superficial Siderosis Associated With a Treatment Spinal Arteriovenous Malformation, Wouter I. Schievink, Paul J. Apostolides, and Robert F. Spetzler

Rupture of a Previously Documented Small Asymptomatic Intracranial Aneurysm in a Patient With Autosomal Dominant Polycystic Kidney Disease, Wouter I. Schievink, Virginia Prendergast, and Joseph M. Zabramski

Enhanced endogenous antioxidant activity and inhibition of cerebral vasospasm in rabbits by pretreatment with a nontoxic endotoxin analog, monophosphoryl lipid A., T Toyoda, A L Kwan, M Bavbek, N F Kassell, John E Wanebo, and K S Lee

Long-Term Graft Patency Rates and Clinical Outcomes After Revascularization for Symptomatic Traumatic Internal Carotid Artery Dissection, A. Giancarlo Vishteh, Frederick F. Marciano, Carlos A. David, Wouter I. Schievink, Joseph M. Zabramski, and Robert F. Spetzler

Thoracoscopic Approaches to the Thoracic Spine, M. Visocchi, R. Masferrer, Volker K.H. Sonntag, and C. A. Dickman

Systemic administration of the endothelin-A receptor antagonist TBC 11251 attenuates cerebral vasospasm after experimental subarachnoid hemorrhage: dose study and review of endothelin-based therapies in the literature on cerebral vasospasm., John E Wanebo, A S Arthur, H G Louis, K West, N F Kassell, K S Lee, and G A Helm

Orbitozygomatic Craniotomy: Technical Note, Joseph M. Zabramski, Talat Kiriş, Suresh K. Sankhla, Josep Cabiol, and Robert F. Spetzler

Submissions from 1997

Embolization and radiosurgery for AVMs, P J. Apostolides, M T. Lawton, K A. Smith, and R F. Spetzler

Reversed-Flow Saphenous Vein Grafts for Cerebral Revascularization: Technical Note, Carlos A. David, Joseph M. Zabramski, and Robert F. Spetzler

Foramen Magnum Meningiomas, C. A. David and Robert F. Spetzler

De Novo Formation of a Central Nervous System Cavernous Malformation: Implications for Predicting Risk of Hemorrhage. Case Report and Review of the Literature, Paul W. Detwiler, Randall W. Porter, Joseph M. Zabramski, and Robert F. Spetzler

Detection of delayed cerebral vasospasm, after rupture of intracranial aneurysms, by magnetic resonance angiography, P W. Detwiler, R Porter, M T. Lawton, and R F. Spetzler

Degenerative Lumbar Spinal Instability: Technical Aspects of Operative Treatment, D. G. Karahalios, P. J. Apostolides, and Volker K.H. Sonntag

Neurosurgery at the Barrow Neurological Institute, Shelley A. Kick, Volker K.H. Sonntag, and Robert F. Spetzler

Management of arteriovenous malformations: Part II, S Kobayashi, K Hongo, S N. Bhagwati, Z H. Rappaport, M T. Lawton, and R F. Spetzler

Management of arteriovenous malformations: Part II., S. Kobayashi, K. Hongo, S. N. Bhagwati, Z. H. Rappaport, M. T. Lawton, and R. F. Spetzler

Technical aspects and recent trends in the management of large and giant midbasilar artery aneurysms, Michael T. Lawton, C. Phillip Daspit, and Robert F. Spetzler

Juvenile Active Ossifying Fibroma: Report of Four Cases, Michael T. Lawton, Joseph E. Heiserman, Stephen W. Coons, Bruce D. Ragsdale, and Robert F. Spetzler

Redefined role of angiogenesis in the pathogenesis of dural arteriovenous malformations, Michael T. Lawton, Ronald Jacobowitz, and Robert F. Spetzler

Presigmoid approaches to skull base lesions, M T. Lawton, C P. Daspit, and R F. Spetzler

Treatment for Intracranial Dural Arteriovenous Malformations: A Meta- Analysis From the English Language Literature, Ceasar P. Lucas, Joseph M. Zabramski, Robert F. Spetzler, and Ronald Jacobowitz

Linkage of the Locus for Cerebral Cavernous Hemangiomas to Human Chromosome 7Q in Four Families of Mexican-American Descent, M. H. Polymeropoulos, O. Hurko, F. Hsu, J. Rubenstein, S. Basnet, K. Lane, H. Dietz, Robert F. Spetzler, and D. Rigamonti

Concurrent aneurysm rupture and thrombosis of high grade internal carotid artery stenosis: Report of two cases, Randall W. Porter, Michael T. Lawton, Mark G. Hamilton, and Robert F. Spetzler

Operative Approaches for Intractable Temporal Lobe Epilepsy, Kris A. Smith and Andrew G. Shetter

Discussion on Newly Diagnosed Rheumatoid With Lower Cranial Nerve Abnormalities, Volker K.H. Sonntag

Neurosurgical Spine Fellowships: the Phoenix Model, Volker K.H. Sonntag

Bone Flap Fixation: A New Technique, Robert F. Spetzler

Attenuation of cerebral vasospasm by systemic administration of an endothelin-A receptor antagonist, TBC 11251, in a rabbit model of subarachnoid hemorrhage., John E Wanebo, H G Louis, A S Arthur, J Zhou, N F Kassell, K S Lee, and G A Helm

Submissions from 1996

Link

Intracranial chondroma arising from the cranial vault: CT and MR appearance, K Abdelhamid, L R. Camras, E M. Nijensohn, G L. Rosseau, and L J. Cerullo

Characteristics and Surgical Treatment of Dolichoectatic and Fusiform Aneurysms, John A. Anson, Michael T. Lawton, and Robert F. Spetzler

Threaded Steinmann Pin Fusion of the Craniovertebral Junction, Paul J. Apostolides, Curtis A. Dickman, John G. Golfinos, Stephen M. Papadopoulos, and Volker K.H. Sonntag

Intra-Aortic Balloon Pump Counterpulsation in the Management of Concomitant Cerebral Vasospasm and Cardiac Failure After Subarachnoid Hemorrhage: Technical Case Report, Paul J. Apostolides, Karl A. Greene, Joseph M. Zabramski, John W. Fitzgerald, and Robert F. Spetzler

Dorsal Laminectomy in the Adult Mouse: A Model for Nervous System Research, Dilantha B. Ellegala, J. Channing Tassone, Anthony M. Avellino, Cynthia A. Pekow, Michael L. Cunningham, and Michel Kliot

Titanium aneurysm clips: Part II--Seizure and electroencephalographic studies in implanted rabbits, R S. Fisher, T Ehsan, K Smith, M T. Lawton, W D. Bichard, and R F. Spetzler

Spinal epidural hematoma [6], D. Foo, M. T. Lawton, V. K.H. Sonntag, and C. A. Dickman

Transpetrosal and Combination Approaches to Skull Base Lesions, Michael T. Lawton, C. P. Daspit, and Robert F. Spetzler

The Contralateral Transcallosal Approach: Experience With 32 Patients, Michael T. Lawton, John G. Golfinos, and Robert F. Spetzler

Revascularization and aneurysm surgery: Current techniques, indications, and outcome, Michael T. Lawton, Mark G. Hamilton, Jacques J. Morcos, and Robert F. Spetzler

Titanium Aneurysm Clips: Part I - Mechanical Radiological and Biocompatibility Testing, Michael T. Lawton, James C. Ho, William D. Bichard, Stephen W. Coons, Joseph M. Zabramski, and Robert F. Spetzler

Internal Carotid Artery Sacrifice for Radical Resection of Skull Base Tumors, Michael T. Lawton and Robert F. Spetzler

Titanium aneurysm clips: Part III--Clinical application in 16 patients with subarachnoid hemorrhage, M T. Lawton, J E. Heiserman, V C. Prendergast, J M. Zabramski, and R F. Spetzler

The Anatomical Suitability of the C1-2 Complex for Transarticular Screw Fixation, Christopher G. Paramore, Curtis A. Dickman, and Volker K.H. Sonntag

Submissions from 1995

Ectomesenchymal Hamartoma (Benign "ectomesenchymoma") of the VIIIth Nerve: Case Report, Paul J. Apostolides, Robert F. Spetzler, and Peter C. Johnson

Differential macrophage responses in the peripheral and central nervous system during wallerian degeneration of axons., A M Avellino, D Hart, A T Dailey, M MacKinnon, D Ellegala, and M Kliot

Link

Differential macrophage responses in the peripheral and central nervous system during wallerian degeneration of axons, Anthony M. Avellino, David Hart, Andrew T. Dailey, Michael Mackinnon, Dilantha Ellegala, and Michel Kliot

Novel Heuristics of Functional Neural Networks: Implications for Future Strategies in Functional Neurosurgery, Konstantin V. Baev, Karl A. Greene, Frederick F. Marciano, Andrew G. Shelter, Abraham N. Lieberman, and Robert F. Spetzler

Posterior Skull Base Transfacial Approaches, S. P. Beals, E. F. Joganic, M. G. Hamilton, and Robert F. Spetzler

A Gene Responsible for Cavernous Malformations of the Brain Maps to Chromosome 7Q, Jan Dubovsky, Joseph M. Zabramski, Janice Kurth, Robert F. Spetzler, Steven S. Rich, Harry T. Orr, and James L. Weber

Clinical Use of a Frameless Stereotactic Arm: Results of 325 Cases, J. G. Golfinos, Brian C. Fitzpatrick, L. R. Smith, and Robert F. Spetzler

Neurosurgery in 50 Years, Harold J. Hoffman and Robert F. Spetzler

Ruptured Giant Aneurysm of an Occluded Middle Cerebral Artery in a Severe-Grade Patient: Case Report, Gary E. Kraus, James M. Herman, Frederick F. Marciano, and Robert F. Spetzler

Multimodality Treatment of Deep Arteriovenous Malformations: Thalamus Basal Ganglia and Brain Stem, Michael T. Lawton, Mark G. Hamilton, and Robert F. Spetzler

Radical Resection of Anterior Skull Base Tumors, Michael T. Lawton, M. G. Hamilton, S. P. Beals, E. F. Joganic, and R. F. Spetzler

Surgical Management of Giant Intracranial Aneurysms: Experience With 171 Patients, Michael T. Lawton and Robert F. Spetzler

Surgical management of spinal epidural hematoma: Relationship between surgical timing and neurological outcome, M. T. Lawton, R. W. Porter, J. E. Heiserman, R. Jacobowitz, V. K.H. Sonntag, and C. A. Dickman

Advances in Spinal Instrumentation, C. G. Paramore and Volker K.H. Sonntag

Current challenges in management of cranial base meningiomas., G Rosseau and L Cerullo

Supratentorial-Infraoccipital Approach for Posteromedial Temporal Lobe Lesions, Kris A. Smith and Robert F. Spetzler

Is Fusion Indicated for Lumbar Spinal Disorders?, Volker K.H. Sonntag and Frederick F. Marciano