Computational Approach to Quantifying Hemodynamic Forces in Giant Cerebral Aneurysms
Document Type
Article
Abstract
BACKGROUND AND PURPOSE: The options for treating giant fusiform basilar aneurysms are limited, and the potential impact of planned interventions is difficult to assess. We developed a computational framework to evaluate the impact that interventions might have on hemodynamic conditions. METHODS: A computational fluid dynamics approach was used to determine the velocity field, wall shear stress, and pressure distribution within a model of a basilar artery before and after a simulated occlusion of one vertebral artery. The vascular geometry in a patient with a giant fusiform basilar artery aneurysm was determined by using contrast-enhanced MR angiography, and the numerical simulation approach was used to calculate the flow fields in the presenting geometry and to predict the flow field that would occur if a vertebral artery were occluded. RESULTS: In the model geometry, computational fluid dynamics indicated that there would be a symmetric flow pattern with a strong central stream and large recirculation zones at the walls. After simulated occlusion of one vertebral artery, the primary stream was diverted to one side, resulting in high pressure and increased wall shear stress. For the patient-specific geometry, flow patterns were shown to depend strongly on how much flow there was in each vertebral artery. CONCLUSION: Contrast-enhanced MR angiography is an effective tool for demonstrating the luminal boundaries of large intracranial aneurysms. Computational fluid dynamics is a powerful tool for determining the prevailing flow conditions in vascular territories and for modeling the possible alterations of the flow field that would result from interventional treatments.
Publication Date
10-1-2003
Publication Title
American Journal of Neuroradiology
ISSN
01956108
Volume
24
Issue
9
First Page
1804
Last Page
1810
PubMed ID
14561606
Recommended Citation
Jou, Liang Der; Quick, Christopher M.; Young, William L.; Lawton, Michael T.; Higashida, Randall; Martin, Alastair; and Saloner, David, "Computational Approach to Quantifying Hemodynamic Forces in Giant Cerebral Aneurysms" (2003). Neurosurgery. 870.
https://scholar.barrowneuro.org/neurosurgery/870