The Barrow Neurological Institute is proud of its reputation as a medical research facility and is home to some of the most sophisticated research programs outside of an academic setting in the Southwestern United States. Researchers in the Barrow Neurosurgery Research Center are devoted to learning more about the causes of and treatments for a wide range of disorders, such as stroke, aneurysms, spinal cord injury, and hydrocephalus. Our research has led to treatments that are being used around the world. Within the Department are neurosurgeons who subspecialize in cerebrovascular and skull base, functional and stereotactic, pediatric, spine, tumor, and endovascular neurosurgery.
Physicians, scientists, and expert clinical staff come together with a commitment to developing new techniques for the prevention, diagnosis, treatment, and rehabilitation of neurological illnesses and injuries. The leadership of internationally respected physicians keeps Barrow at the forefront of neuroscience. The compassionate expertise of its extensive staff of nurses, technologists, therapists and support personnel is evident in every aspect of care provided.
Our mission is to advance the knowledge and practice of medicine in neuroscience through basic and clinical research, education of medical professionals, and innovation in clinical techniques and technology.
Submissions from 2013
Minimally Invasive Transforaminal Lumbar Interbody Fusions and Fluoroscopy: A Low-Dose Protocol to Minimize Ionizing Radiation, Justin C. Clark, Gary Jasmer, Frederick F. Marciano, and Luis M. Tumialán
Defining the Limits of the Occipital Transtentorial Keyhole Approach, Justin C. Clark and Robert F. Spetzler
Rhythmical and Periodic Eeg Patterns do not Predict Short-Term Outcome in Critically Ill Patients With Subarachnoid Hemorrhage, Amy Z. Crepeau, John F. Kerrigan, Paula Gerber, Gunjan Parikh, Heidi Jahnke, Peter Nakaji, Andrew S. Little, and Kevin E. Chapman
Mechanical Thrombectomy as First-Line Treatment for Venous Sinus Thrombosis: Technical Considerations and Preliminary Results Using the Angiojet Device, Shervin R. Dashti, Yin C. Hu, Tom Yao, David Fiorella, Alim P. Mitha, Felipe C. Albuquerque, and Cameron G. McDougall
Perioperative management of coagulation in nontraumatic intracerebral hemorrhage, Vincent Degos, Erick M. Westbroek, Michael T. Lawton, J. Claude Hemphill, Gregory J. Del Zoppo, and William L. Young
The Evolution of Endovascular Treatment of Carotid Cavernous Fistulas: A Single-Center Experience, Andrew F. Ducruet, Felipe C. Albuquerque, R. Webster Crowley, and Cameron G. McDougall
Reconstructive Endovascular Treatment of a Ruptured Vertebral Artery Dissecting Aneurysm Using the Pipeline Embolization Device, Andrew F. Ducruet, R. Webster Crowley, Felipe C. Albuquerque, and Cameron G. McDougall
Long-term clinical and radiographic stability after clip reconstruction of a midbasilar dissecting mycotic aneurysm., David J Fusco, Walter J Jermakowicz, Giacomo D Consiglieri, and Robert F Spetzler
Temporal lobe arteriovenous malformations: anatomical subtypes, surgical strategy, and outcomes, Andreu Gabarrós Canals, Ana Rodríguez-Hernández, William L. Young, and Michael T. Lawton
Histopathological Features of the Outer Membrane of Chronic Subdural Hematoma and Correlation With Clinical and Radiological Features, Gurpreet S. Gandhoke, Mohammad Kaif, Lawrence Choi, Richard W. Williamson, and Peter Nakaji
The impact of adjuvant stereotactic radiosurgery on atypical meningioma recurrence following aggressive microsurgical resection., Douglas A Hardesty, Andrew B Wolf, David G Brachman, Heyoung L McBride, Emad Youssef, Peter Nakaji, Randall W Porter, Kris A Smith, Robert F Spetzler, and Nader Sanai
Interactions between programmable shunt valves and the iPad 3 with Smart Cover, Yizheng He, Rory K. Murphy, Jarod L. Roland, and David D. Limbrick
Mini supraorbital approach to inferior frontal lobe cavernous malformations: case series, Michael E. Ivan and Michael T. Lawton
Cerebral herniation as a complication of chest tube drainage of cerebrospinal fluid after injury to the spine, M Yashar Kalani, Aristotelis Filippidis, Nikolay L. Martirosyan, and Nicholas Theodore
Cerebral revascularization and carotid artery resection at the skull base for treatment of advanced head and neck malignancies, M Yashar Kalani, Samuel Kalb, Nikolay L. Martirosyan, Salvatore C. Lettieri, Robert F. Spetzler, Randall W. Porter, and Iman Feiz-Erfan
Bypass and Flow Reduction for Complex Basilar and Vertebrobasilar Junction Aneurysms, M. Yashar S. Kalani, Joseph M. Zabramski, Peter Nakaji, and Robert F. Spetzler
Middle cerebral artery aneurysms, Michael T. Lawton
Repair of Cerebrospinal Fluid Fistula From an Invasive Skull Base Prolactinoma Using a Septal Mucosal Vascularized Flap: Technical Case Report, Andrew S. Little
Prospective validation of a patient-reported nasal quality-of-life tool for endonasal skull base surgery: The Anterior Skull Base Nasal Inventory-12, Andrew S. Little, Daniel Kelly, John Milligan, Chester Griffiths, Gail Rosseau, Daniel M. Prevedello, Ricardo Carrau, Heidi Jahnke, Charlene Chaloner, Judith O'Leary, Kristina Chapple, Peter Nakaji, and William L. White
Endoscopic Endonasal Transmaxillary Approach and Endoscopic Sublabial Transmaxillary Approach: Surgical Decision-Making and Implications of the Nasolacrimal Duct, Andrew S. Little, Peter Nakaji, and John Milligan
Multilevel Anterior Cervical Discectomy and Fusion With and Without Rhbmp-2: A Comparison of Dysphagia Rates and Outcomes in 150 Patients - Clinical Article, Daniel C. Lu, Luis M. Tumialán, and Dean Chou
Electromagnetic Stereotactic Navigation for External Ventricular Drain Placement in the Intensive Care Unit, Mark Mahan, Robert F. Spetzler, and Peter Nakaji
Comparative analysis of isocentric 3-dimensional C-arm fluoroscopy and biplanar fluoroscopy for anterior screw fixation in odontoid fractures, Nikolay L. Martirosyan, Samuel Kalb, Daniel D. Cavalcanti, Richard A. Lochhead, Timothy D. Uschold, Amanda Loh, and Nicholas Theodore
Multimodality Management of Vertebral Artery Injury Sustained During Cervical or Craniocervical Surgery, Peter Hanks Maughan, Andrew F. Ducruet, Ali M. Elhadi, Nikolay L. Martirosyan, Mark P. Garrett, Raza Mushtaq, Felipe C. Albuquerque, and Nicholas Theodore
Gamma knife surgery for a hemangioma of the cavernous sinus in a child, Rory K. Murphy, Matthew R. Reynolds, David B. Mansur, and Matthew D. Smyth
Surgical management and clinical outcomes of multiple-level symptomatic herniated thoracic discs, Mark E. Oppenlander, Justin C. Clark, James Kalyvas, and Curtis A. Dickman
Deep arteriovenous malformations in the basal ganglia, thalamus, and insula: Microsurgical management, techniques, and results, Matthew B. Potts, William L. Young, and Michael T. Lawton
Current management and surgical outcomes of medically intractable epilepsy, Wyatt L. Ramey, Nikolay L. Martirosyan, Corinne M. Lieu, Hasnain A. Hasham, G Michael Lemole, and Martin E. Weinand
Acute Hemorrhage Following Gamma Knife Radiosurgery to a Clival Meningioma, Matthew R. Reynolds, Ammar H. Hawasli, Rory K. Murphy, Wilson Z. Ray, Joseph R. Simpson, Robert E. Drzymala, and Keith M. Rich
Posterior inferior cerebellar artery aneurysms, Ana Rodríguez-Hernández, Ahmed J. Awad, and Michael T. Lawton
Superior cerebellar artery-posterior cerebral artery bypass: In situ bypass for posterior cerebral artery revascularization - Technical note, Ana Rodríguez-Hernández, Christina Huang, and Michael T. Lawton
Superior cerebellar artery-posterior cerebral artery bypass: in situ bypass for posterior cerebral artery revascularization, Ana Rodríguez-Hernández, Christina Huang, and Michael T. Lawton
Contralateral transcallosal approach to basal ganglia cavernous malformation: 3-dimensional operative video, Ana Rodríguez-Hernández and Michael T. Lawton
Distal aneurysms of intracranial arteries: Application of numerical nomenclature, predilection for cerebellar arteries, and results of surgical management, Ana Rodríguez-Hernández, Zsolt Zador, Ruben Rodríguez-Mena, and Michael T. Lawton
The development of a virtual simulator for training neurosurgeons to perform and perfect endoscopic endonasal transsphenoidal surgery, Gail Rosseau, Julian Bailes, Rolando del Maestro, Anne Cabral, Nusrat Choudhury, Olivier Comas, Patricia Debergue, Gino De Luca, Jordan Hovdebo, Di Jiang, Denis Laroche, Andre Neubauer, Valerie Pazos, Francis Thibault, and Robert Diraddo
The evolution of image guidance in transsphenoidal pituitary surgery, Gail L. Rosseau
Flow Diverter Effect on Cerebral Aneurysm Hemodynamics: an in Vitro Comparison of Telescoping Stents and the Pipeline, Breigh N. Roszelle, L. Fernando Gonzalez, M. Haithem Babiker, Justin Ryan, Felipe C. Albuquerque, and David H. Frakes
Treatment of recurrent, multiloculated, obstructive hydrocephalus with suprahepatic peritoneal catheter placement, Nathan C. Rowland, Michael C. Huang, Michael T. Lawton, Jonathan Carter, John Maa, and Michael W. McDermott
Intraoperative rerupture during surgical treatment of aneurysmal subarachnoid hemorrhage is not associated with an increased risk of vasospasm, Sunil A. Sheth, Daniel Hausrath, Adam L. Numis, Michael T. Lawton, and S Andrew Josephson
Atlantoaxial Stabilization: A Minimally Invasive Alternative, Volker K.H. Sonntag
No Movement No Cyst, Volker K.H. Sonntag
Pedicle Screw Fixation Made Safer By the Use of Computed Tomography-Guided Intraoperative Navigation, Volker K.H. Sonntag
The Barrow Ruptured Aneurysm Trial: 3-Year Results: Clinical Article, Robert F. Spetzler, Cameron G. McDougall, Felipe C. Albuquerque, Joseph M. Zabramski, Nancy K. Hills, Shahram Partovi, Peter Nakaji, and Robert C. Wallace
Subaxial cervical juxtafacet cysts: single institution surgical experience and literature review., Timothy Uschold, Jaykar Panchmatia, David J Fusco, Adib A Abla, Randall W Porter, and Nicholas Theodore
A Statistical Method for Predicting Seizure Onset Zones From Human Single-Neuron Recordings, André B. Valdez, Erin N. Hickman, David M. Treiman, Kris A Smith, and Peter N. Steinmetz
Brain surgery in the bush: Adapting techniques and technology to fit the developing world, Jan Vargas, Emanuel Mayegga, Emmanuel Nuwas, Dilantha B. Ellegala, Elisa J. Kucia, and Joyce Nicholas
G Protein-Coupled Receptor 124 (GPR124) Gene Polymorphisms and Risk of Brain Arteriovenous Malformation, Shantel Weinsheimer, Ari D. Brettman, Ludmila Pawlikowska, D Christine Wu, Michael R. Mancuso, Frank Kuhnert, Michael T. Lawton, Stephen Sidney, Jonathan G. Zaroff, Charles E. McCulloch, William L. Young, Calvin Kuo, and Helen Kim
Endoscopic Resection of Colloid Cysts: Use of a Dual-Instrument Technique and an Anterolateral Approach, David A. Wilson, David J. Fusco, Scott D. Wait, and Peter Nakaji
Malignant transformation of a vestibular schwannoma after gamma knife radiosurgery., Vijay Yanamadala, Richard W Williamson, David J Fusco, Jennifer M Eschbacher, Peter Weisskopf, and Randall W Porter
Retropharyngeal ganglioneuroma: a case report, Andrew I. Yang, Jessica Ozsvath, Pratibha Shukla, and Girish M. Fatterpekar
Submissions from 2012
Visual Impairment After Endovascular Treatment: Does Stent Placement Increase the Incidence?, Felipe C. Albuquerque
Cerebral Cavernous Malformations: From Genes to Proteins to Disease - Clinical Article, Daniel D. Cavalcanti, M. Yashar S. Kalani, Nikolay L. Martirosyan, Justin Eales, Robert F. Spetzler, and Mark C. Preul
Biomechanics of a Fixed-Center of Rotation Cervical Intervertebral Disc Prosthesis, Neil R. Crawford, Seungwon Baek, Anna G.U. Sawa, Sam Safavi-Abbasi, Volker K.H. Sonntag, and Neil Duggal
The Art of Neuroanatomy, Katharine Cronk and Robert F. Spetzler
Technical Considerations in the Endovascular Management of Aneurysms of the Posterior Inferior Cerebellar Artery, R. Webster Crowley, Felipe C. Albuquerque, Andrew F. Ducruet, Richard W. Williamson, and Cameron G. McDougall
Comparative effectiveness of treatments for cerebral arteriovenous malformations: Trends in nationwide outcomes from 2000 to 2009, Jason M. Davies, Vijay Yanamadala, and Michael T. Lawton
Fedor Krause: the first systematic use of X-rays in neurosurgery, Ali M. Elhadi, Samuel Kalb, Nikolay L. Martirosyan, Abhishek Agrawal, and Mark C. Preul
The Journey of Discovering Skull Base Anatomy in Ancient Egypt and the Special Influence of Alexandria, Ali M. Elhadi, Samuel Kalb, Luis Perez-Orribo, Andrew S. Little, Robert F. Spetzler, and Mark C. Preul
Seizure predictors and control after microsurgical resection of supratentorial arteriovenous malformations in 440 patients, Dario J. Englot, William L. Young, Seunggu J. Han, Charles E. McCulloch, Edward F. Chang, and Michael T. Lawton
In Vivo Intraoperative Confocal Microscopy for Real-Time Histopathological Imaging of Brain Tumors: Clinical Article, Jennifer Eschbacher, Nikolay L. Martirosyan, Peter Nakaji, Nader Sanai, Mark C. Preul, Kris A. Smith, Stephen W. Coons, and Robert F. Spetzler
An Anatomical Analysis of the Mini-Modified Orbitozygomatic and Supra-Orbital Approaches, Eberval G. Figueiredo, Puspha Deshmukh, Peter Nakaji, Edson Bor Seng Shu, Neil Crawford, Robert F. Spetzler, and Mark C. Preul
Eagle's Syndrome: Embryology Anatomy and Clinical Management, David J. Fusco, Shahab Asteraki, and Robert F. Spetzl
Anatomical Study on the "Perforator-Free Zone": Reconsidering the Proximal Superior Cerebellar Artery and Basilar Artery Perforators, Ulises Garcia-Gonzalez, Daniel D. Cavalcanti, Abhishek Agrawal, Robert F. Spetzler, and Mark C. Preul
Surgical Treatment of Blister-Like Aneurysms, Mark P. Garrett and Robert F. Spetzler
Silent intralesional microhemorrhage as a risk factor for brain arteriovenous malformation rupture, Yi Guo, Tara Saunders, Hua Su, Helen Kim, Deniz Akkoc, David A. Saloner, Steven W. Hetts, Christopher Hess, Michael T. Lawton, Andrew W. Bollen, Tony Pourmohamad, Charles E. McCulloch, Tarik Tihan, and William L. Young
Ferumoxytol-enhanced MRI to Image Inflammation within Human Brain Arteriovenous Malformations: A Pilot Investigation, David M. Hasan, Matthew Amans, Tarik Tihan, Christopher Hess, Yi Guo, Soonmee Cha, Hua Su, Alastair J. Martin, Michael T. Lawton, Edward A. Neuwelt, David A. Saloner, and William L. Young
Macrophage imaging within human cerebral aneurysms wall using ferumoxytol-enhanced MRI: A pilot study, David M. Hasan, Kelly B. Mahaney, Vincent A. Magnotta, David K. Kung, Michael T. Lawton, Tomoki Hashimoto, H. Richard Winn, David Saloner, Alastair Martin, Seymur Gahramanov, Edit Dósa, Edward Neuwelt, and William L. Young
Magnetic resonance imaging-guided focused laser interstitial thermal therapy for subinsular metastatic adenocarcinoma: technical case report, Ammar H. Hawasli, Wilson Z. Ray, Rory K. Murphy, Ralph G. Dacey, and Eric C. Leuthardt
Pediatric intracranial nongalenic pial arteriovenous fistulas: Clinical features, angioarchitecture, and outcomes, Steven W. Hetts, K. Keenan, H. J. Fullerton, W. L. Young, J. D. English, N. Gupta, C. F. Dowd, R. T. Higashida, M. T. Lawton, and V. V. Halbach
Spinal dural arteriovenous fistulas and intrathecal venous drainage: correlation between digital subtraction angiography, magnetic resonance imaging, and clinical findings, Steven W. Hetts, Parham Moftakhar, Joey D. English, Christopher F. Dowd, Randall T. Higashida, Michael T. Lawton, Vanja C. Douglas, and Van V. Halbach
Neuropsychological outcome following minimal access subtemporal selective amygdalohippocampectomy., Stacy W Hill, Shawn D Gale, Caleb Pearson, and Kris A Smith
Reevaluating the imaging definition of tumor progression: perfusion MRI quantifies recurrent glioblastoma tumor fraction, pseudoprogression, and radiation necrosis to predict survival., Leland S Hu, Jennifer M Eschbacher, Joseph E Heiserman, Amylou C Dueck, William R Shapiro, Seban Liu, John P Karis, Kris A Smith, Stephen W Coons, Peter Nakaji, Robert F Spetzler, Burt G Feuerstein, Josef Debbins, and Leslie C Baxter
Perlecan domain v is upregulated in human brain arteriovenous malformation and could mediate the vascular endothelial growth factor effect in lesional tissue, Michael P. Kahle, Boyeon Lee, Tony Pourmohamad, Austin Cunningham, Hua Su, Helen Kim, Yongmei Chen, Charles E. McCulloch, Nicholas M. Barbaro, Michael T. Lawton, William L. Young, and Gregory J. Bix
Microsurgical clipping of an unruptured lenticulostriate aneurysm, M Yashar Kalani, Nikolay L. Martirosyan, Peter Nakaji, and Robert F. Spetzler
Surgical and Endovascular Treatment of Pediatric Spinal Arteriovenous Malformations, M. Yashar S. Kalani, Azam S. Ahmed, Nikolay L. Martirosyan, Katharine Cronk, Karam Moon, Felipe C. Albuquerque, Cameron G. McDougall, Robert F. Spetzler, and Ruth E. Bristol
Spinal Intradural Teratomas: Developmental Programs Gone Awry?, M. Yashar S. Kalani, Sudarshan Iyer, Stephen W. Coons, and Kris A. Smith
Genetics of the degenerated intervertebral disc, Samuel Kalb, Nikolay L. Martirosyan, M Yashar Kalani, Guy G. Broc, and Nicholas Theodore
Evaluation of Operative Procedures for Symptomatic Outcome After Decompression Surgery for Chiari Type I Malformation, Samuel Kalb, Luis Perez-Orribo, Mark Mahan, Nicholas Theodore, Peter Nakaji, and Ruth E. Bristol
Control of MicroRNA-21 expression in colorectal cancer cells by oncogenic epidermal growth factor/Ras signaling and Ets transcription factors, Hanna B. Kern, Brian F. Niemeyer, Janet K. Parrish, Carol A. Kerr, Nasser K. Yaghi, Jason D. Prescott, Arthur Gutierrez-Hartmann, and Paul Jedlicka
Neurosurgery in tanzania: A discussion of culture, socioeconomics, and humanitarians, Abednego Kinasha, Elisa J. Kucia, Jan Vargas, Joseph Kavolus, Jordan Magarik, Dilantha B. Ellegala, and Joyce Nicholas
Spinal cord infarction associated with subarachnoid hemorrhage, Vibhor Krishna, Christos Lazaridis, Dilantha Ellegala, Steven Glazier, Mark Kindy, Maria Spampinato, and Julio A. Chalela
Arizona at the Center of the U.S. Immigration Debate: U.S. Supreme Court Rules on Controversial State Immigration Law S.B. 1070, Andrew S. Little
The Anterior Skull Base Nasal Inventory (Ask Nasal Inventory): A Clinical Tool for Evaluating Rhinological Outcomes After Endonasal Surgery for Pituitary and Cranial Base Lesions, Andrew S. Little, Heidi Jahnke, Peter Nakaji, John Milligan, Kristina Chapple, and William L. White
Analysis of the subcomponents and cortical terminations of the perisylvian superior longitudinal fasciculus: a fiber dissection and DTI tractography study, Juan Martino, Philip C. De Witt Hamer, Mitchel S. Berger, Michael T. Lawton, Christine M. Arnold, Enrique Marco de Lucas, and Hugues Duffau
Repair of a median nerve transection injury using multiple nerve transfers, with long-term functional recovery, Rory K. Murphy, Wilson Z. Ray, and Susan E. Mackinnon
Revascularization and Cerebral Hyperperfusion: We Know What but not Why, Peter Nakaji
Clinical status epilepticus due to anaplastic cortical ependymoma., Victoria Ohla, Kris A Smith, and Cornelia Drees
Spinal and paraspinal giant cervical cavernous malformation with postpartum presentation, Mark E. Oppenlander, M Yashar Kalani, and Curtis A. Dickman
Transsylvian-transinsular approaches to the insula and basal ganglia: Operative techniques and results with vascular lesions, Matthew B. Potts, Edward F. Chang, William L. Young, and Michael T. Lawton
Impact of lateral mass anatomic variation on ideal polyaxial screw head mobility: technical considerations, Wilson Z. Ray, Rory K. Murphy, Ian G. Dorward, Eriks A. Lusis, Spiros L. Blackburn, and Todd Stewart
Medial pectoral nerve to axillary nerve neurotization following traumatic brachial plexus injuries: indications and clinical outcomes, Wilson Z. Ray, Rory K. Murphy, Katherine Santosa, Philip J. Johnson, and Susan E. Mackinnon
Perimesencephalic subarachnoid hemorrhage associated with a painless, pupillary-involving third cranial nerve palsy: case report and literature review, Matthew R. Reynolds, Rafael A. Vega, Rory K. Murphy, Michelle M. Miller-Thomas, and Gregory J. Zipfel
Contralateral clipping of middle cerebral artery aneurysms: rationale, indications, and surgical technique, Ana Rodríguez-Hernández, Andreu Gabarrós, and Michael T. Lawton
Bypass for the prevention of ischemic stroke, Ana Rodríguez-Hernández, S Andrew Josephson, Andrew S. Josephson, David Langer, and Michael T. Lawton
Bypass surgery for the prevention of ischemic stroke: current indications and techniques, Ana Rodríguez-Hernández, Scott Andrew Josephson, and Michael T. Lawton
Coment on the study "abordaje contralateral en aneurismas de la arteria cerebral media con segmento M1 largo: A propósito de dos casos" de Arrese et al, Ana Rodríguez-Hernández and Michael T. Lawton
Management of a recurrent coiled giant posterior cerebral artery aneurysm with trapping and thrombectomy: 3-dimensional operative video, Ana Rodríguez-Hernández and Michael T. Lawton
Twiglike middle cerebral arteries, Ana Rodríguez-Hernández, Susanna Miric, and Michael T. Lawton
Current management of middle cerebral artery aneurysms: surgical results with a "clip first" policy, Ana Rodríguez-Hernández, Michael E. Sughrue, Sina Akhavan, Julian Habdank-Kolaczkowski, and Michael T. Lawton
Emerging Operative Strategies in Neurosurgical Oncology, Nader Sanai