The Barrow Neurological Institute is proud of its reputation as a medical research facility and is home to some of the most sophisticated research programs outside of an academic setting in the Southwestern United States. Researchers in the Barrow Neurosurgery Research Center are devoted to learning more about the causes of and treatments for a wide range of disorders, such as stroke, aneurysms, spinal cord injury, and hydrocephalus. Our research has led to treatments that are being used around the world. Within the Department are neurosurgeons who subspecialize in cerebrovascular and skull base, functional and stereotactic, pediatric, spine, tumor, and endovascular neurosurgery.
Physicians, scientists, and expert clinical staff come together with a commitment to developing new techniques for the prevention, diagnosis, treatment, and rehabilitation of neurological illnesses and injuries. The leadership of internationally respected physicians keeps Barrow at the forefront of neuroscience. The compassionate expertise of its extensive staff of nurses, technologists, therapists and support personnel is evident in every aspect of care provided.
Our mission is to advance the knowledge and practice of medicine in neuroscience through basic and clinical research, education of medical professionals, and innovation in clinical techniques and technology.
Submissions from 2012
Advanced Technical Skills are Required for Microsurgical Clipping of Posterior Communicating Artery Aneurysms in the Endovascular Era, Nader Sanai, Nolan Caldwell, Dario J. Englot, and Michael T. Lawton
Magnetic Resonance Imaging Volumetric Assessment of the Extent of Contrast Enhancement and Resection in Oligodendroglial Tumors: Clinical Article, Tejas Sankar, Nina Z. Moore, Joshua Johnson, Lynn S. Ashby, Adrienne C. Scheck, William R. Shapiro, Kris A Smith, Robert F Spetzler, and Mark C Preul
Concussions in Soccer: Use Your Head - but not as a Weapon, Volker K.H. Sonntag
Lumbar and Cervical Disc Herniations: A Common Problem Many Solutions, Volker K.H. Sonntag
Navigation and MRI During Surgery: Spine Advances, Volker K.H. Sonntag
The Asymptomatic Degenerative Cervical Disc: A Dilemma, Volker K.H. Sonntag
The Quiet Revolution: Retractorless Surgery for Complex Vascular and Skull Base Lesions - Clinical Article, Robert F. Spetzler and Nader Sanai
Basilar Artery Thrombosis After Reduction of Cervical Spondyloptosis: A Cautionary Report - Case Report, Luis M. Tumialán and Nicholas Theodore
Spontaneous Intracranial Hypotension: A Case Study, Tammy L. Tyree and Randall W. Porter
Cervical and Lumbar Spinal Arthroplasty: Clinical Review, Timothy D. Uschold, David J. Fusco, R. Germain, L. M. Tumialan, and Steve W. Chang
Duplicated Pituitary Gland and Odontoid Process. A Case Report, Yousef Usta, F. Sakha, William L. White, Andrew S. Little, and L. Knecht
The Far-Lateral Approach and its Variations, Gregory J. Velat and Robert F. Spetzler
Microrna Expression Profile and Differentially-Expressed Genes in Prolactinomas Following Bromocriptine Treatment, Chengde Wang, Zhipeng Su, Nader Sanai, Xiangyang Xue, Lijun Lu, Yunxiang Chen, Jinsen Wu, Weiming Zheng, Qichuan Zhuge, and Zhe Bao Wu
Minocycline- and tetracycline-class antibiotics are protective against partial seizures in vivo, Doris D. Wang, Dario J. Englot, Paul A. Garcia, Michael T. Lawton, and William L. Young
Brain-derived neurotrophic factor Val66Met polymorphism predicts worse functional outcome after surgery in patients with unruptured brain arteriovenous malformation, Erick M. Westbroek, Ludmila Pawlikowska, Michael T. Lawton, Charles E. McCulloch, William L. Young, and Helen Kim
Rapid ventricular pacing: A novel technique to decrease cardiac output for giant basilar aneurysm surgery, Joseph R. Whiteley, Rebecca Payne, Cesar Rodriguez-Diaz, Dilantha B. Ellegala, and Scott T. Reeves
Multimodality Treatment of Conus Medullaris Arteriovenous Malformations: 2 Decades of Experience With Combined Endovascular and Microsurgical Treatments, David A. Wilson, Adib A. Abla, Timothy D. Uschold, Cameron G. McDougall, Felipe C. Albuquerque, and Robert F. Spetzler
Long-term radiosurgical control of subtotally resected adult pineocytomas., David A Wilson, Al-Wala Awad, David Brachman, Stephen W Coons, Heyoung McBride, Emad Youssef, Peter Nakaji, Andrew G Shetter, Kris A Smith, Robert F Spetzler, and Nader Sanai
Survival and Functional Outcome After Surgical Resection of Intramedullary Spinal Cord Metastases, David A. Wilson, David J. Fusco, Timothy D. Uschold, Robert F. Spetzler, and Steve W. Chang
A Simple and Quantitative Method to Predict Symptomatic Vasospasm After Subarachnoid Hemorrhage Based on Computed Tomography: Beyond the Fisher Scale, David A. Wilson, Peter Nakaji, Adib A. Abla, Timothy D. Uschold, David J. Fusco, Mark E. Oppenlander, Felipe C. Albuquerque, Cameron G. McDougall, Joseph M. Zabramski, and Robert F. Spetzler
Cerebral atrophy is associated with development of chronic subdural haematoma, Andrew Il Yang, David S. Balser, Artem Mikheev, Shani Offen, Jason H. Huang, James Babb, Henry Rusinek, and Uzma Samadani
Localization of dense intracranial electrode arrays using magnetic resonance imaging, Andrew I. Yang, Xiuyuan Wang, Werner K. Doyle, Eric Halgren, Chad Carlson, Thomas L. Belcher, Sydney S. Cash, Orrin Devinsky, and Thomas Thesen
The natural history and clinical presentation of cervical spondylotic myelopathy, Chester K. Yarbrough, Rory K. Murphy, Wilson Z. Ray, and Todd J. Stewart
Direct conversion of fibroblasts to functional neurons, M Yashar, S Kalani, and Nikolay Martirosyan
Submissions from 2011
Delayed Presentation of Traumatic Cerebral and Dural Arteriovenous Fistulae After a BB Gun Accident in a Pediatric Patient: Case Report, Adib A. Abla, Felipe C. Albuquerque, Nicholas Theodore, and Robert F. Spetzler
Advances in the Treatment and Outcome of Brainstem Cavernous Malformation Surgery: A Single-Center Case Series of 300 Surgically Treated Patients, Adib A. Abla, Gregory P. Lekovic, Jay D. Turner, Jean G. De Oliveira, Randall W. Porter, and Robert F. Spetzler
Simultaneous posterior communicating artery aneurysm clipping and selective amygdalohippocampectomy via direct lateral access through the mesial temporal lobe to the basal cisterns., Adib A Abla, Kris A Smith, and Peter Nakaji
Comparison of two antibiotic-impregnated ventricular catheters: a prospective sequential series trial., Adib A Abla, Joseph M Zabramski, Heidi Jahnke, David J Fusco, and Peter Nakaji
A Novel Technique of Odontoidoplasty and C1 Arch Reconstruction: Anatomical and Biomechanical Basis, Abhishek Agarwal, Phillip M. Reyes, Ulises Garcia-Gonzalez, Daniel D. Cavalcanti, Steve W. Chang, Nicholas Theodore, Volker K.H. Sonntag, Robert F. Spetzler, Mark C. Preul, and Neil R. Crawford
Arteriovenous Malformations and Associated Aneurysms, Kaith Almefty and Robert F. Spetzler
Cotton-Clipping Technique to Repair Intraoperative Aneurysm Neck Tear: A Technical Note, Daniel L. Barrow and Robert F. Spetzler
Brain arteriovenous malformation multiplicity predicts the diagnosis of hereditary hemorrhagic telangiectasia: quantitative assessment, Aditya Bharatha, Marie E. Faughnan, Helen Kim, Tony Pourmohamad, Timo Krings, Pinar Bayrak-Toydemir, Ludmila Pawlikowska, Charles E. McCulloch, Michael T. Lawton, Christopher F. Dowd, William L. Young, and Karel G. Terbrugge
Temporal stability of dysmorphic fusiform aneurysms of the intracranial internal carotid artery, Loic Boussel, Vitaliy Rayz, Alastair Martin, Michael Lawton, Randall Higashida, Wade S. Smith, William L. Young, and David Saloner
Surgical management and outcome of schwannomas in the craniocervical region, Daniel D. Cavalcanti, Nikolay L. Martirosyan, Ketan Verma, Sam Safavi-Abbasi, Randall W. Porter, Nicholas Theodore, Volker K. Sonntag, Curtis A. Dickman, and Robert F. Spetzler
A Prospective Study of Nonfunctioning Pituitary Adenomas: Presentation Management and Clinical Outcome, Lukui Chen, William L. White, Robert F. Spetzler, and Bainan Xu
Pott Disease in a 13-Month-Old: Case Report, Giac Consigilieri, Udaya Kumar Kakarla, and Nicholas Theodore
Improving surgical outpatient efficiency through mobile phone text messaging, Mark A. Corrigan, Seamus M. McHugh, Rory K. Murphy, Paul Dhillon, Abid Shah, Immanuel Hennessy, Athar Sheikh, Elaine Lehane, and Arnold S. Hill
Classification schemes for arteriovenous malformations, Jason M. Davies, Helen Kim, William L. Young, and Michael T. Lawton
The contralateral transcingulate approach: operative technique and results with vascular lesions, Jason Davies, Rabih G. Tawk, and Michael T. Lawton
Development of an adhesive surgical ward round checklist; a technique to improve patient safety, P. Dhillon, R. K.J. Murphy, H. Ali, Z. Burukan, M. A. Corrigan, A. Sheikh, and A. D.K. Hill
The 2011 Egyptian Revolution: a neurosurgical perspective, Mohamed El-Fiki and Gail Rosseau
Predictors of seizure freedom in the surgical treatment of supratentorial cavernous malformations, Dario J. Englot, Seunggu J. Han, Michael T. Lawton, and Edward F. Chang
Language and motor mapping during resection of brain arteriovenous malformations: Indications, feasibility, and utility, Andreu Gabarrós, William L. Young, Michael W. McDermott, and Michael T. Lawton
Transarterial Onyx Embolization of Sacral Chordoma: Case Report and Review of the Literature, Yin C. Hu, C. Benjamin Newman, Randall W. Porter, and Felipe C. Albuquerque
Craniofacial Approaches to Large Juvenile Angiofibromas: Clinical Article, M. Yashar S. Kalani, Maziyar A. Kalani, Samuel Kalb, Felipe C. Albuquerque, Cameron G. Mcdougall, Peter Nakaji, Robert F. Spetzler, Randall W. Porter, and Iman Feiz-Erfan
Tumoral Calcinosis Presenting as a Deformity of the Thoracic Spine: Case Report, M. Yashar S. Kalani, Nikolay L. Martirosyan, Andrew S. Little, Udaya Kumar Kakarla, and Nicholas Theodore
Analysis of demographics, risk factors, clinical presentation, and surgical treatment modalities for the ossified posterior longitudinal ligament, Samuel Kalb, Nikolay L. Martirosyan, Luis Perez-Orribo, M Yashar Kalani, and Nicholas Theodore
Commentary on "Microporous Polysaccharide Hemospheres (MPH) for Cerebral Hemostasis: A Preliminary Report", James Kalyvas and Robert F. Spetzler
Critical roles of macrophages in the formation of intracranial aneurysm, Yasuhisa Kanematsu, Miyuki Kanematsu, Chie Kurihara, Yoshiteru Tada, Tsung Ling Tsou, Nico Van Rooijen, Michael T. Lawton, William L. Young, Elena I. Liang, Yoshitsugu Nuki, and Tomoki Hashimoto
Stereotactic radiosurgery for chordoma: a report from the North American Gamma Knife Consortium, Hideyuki Kano, Fawaad O. Iqbal, Jason Sheehan, David Mathieu, Zachary A. Seymour, Ajay Niranjan, John C. Flickinger, Douglas Kondziolka, Bruce E. Pollock, Gail Rosseau, Penny K. Sneed, Michael W. McDermott, and L Dade Lunsford
Parafalcine and midline arteriovenous malformations: surgical strategy, techniques, and outcomes, Yong Bae Kim, William L. Young, and Michael T. Lawton
Accurate state estimation from uncertain data and models: an application of data assimilation to mathematical models of human brain tumors, Eric J. Kostelich, Yang Kuang, Joshua M. McDaniel, Nina Z. Moore, Nikolay L. Martirosyan, and Mark C. Preul
History and current state of neurosurgery at the Medical University of South Carolina, Vibhor Krishna, Yasmeen Rauf, Sunil Patel, Steve Glazier, Phanor Perot, and Dilantha B. Ellegala
Biomechanics of Thoracic Short Versus Long Fixation After 3-Column Injury: Laboratory Investigation, Bruno C.R. Lazaro, Fatih Ersay Deniz, Leonardo B.C. Brasiliense, Phillip M. Reyes, Anna G.U. Sawa, Nicholas Theodore, Volker K.H. Sonntag, and Neil R. Crawford
Prophylactic Antibiotic Trends in Transsphenoidal Surgery for Pituitary Lesions, Andrew S. Little and William L. White
Short-Duration Single-Agent Antibiotic Prophylaxis for Meningitis in Trans-Sphenoidal Surgery, Andrew S. Little and William L. White
MR imaging of partially thrombosed cerebral aneurysms: Characteristics and evolution, Alastair J. Martin, S. W. Hetts, W. P. Dillon, R. T. Higashida, V. Halbach, C. F. Dowd, M. T. Lawton, and D. Saloner
Epidermal electronics, Nikolay Martirosyan and M Yashar Kalani
Use of in vivo near-infrared laser confocal endomicroscopy with indocyanine green to detect the boundary of infiltrative tumor, Nikolay L. Martirosyan, Daniel D. Cavalcanti, Jennifer M. Eschbacher, Peter M. Delaney, Adrienne C. Scheck, Mohammed G. Abdelwahab, Peter Nakaji, Robert F. Spetzler, and Mark C. Preul
Aplasia of the anterior arch of atlas associated with multiple congenital disorders: case report, Nikolay L. Martirosyan, Daniel D. Cavalcanti, M Yashar Kalani, Peter H. Maughan, and Nicholas Theodore
Blood supply and vascular reactivity of the spinal cord under normal and pathological conditions, Nikolay L. Martirosyan, Jeanne S. Feuerstein, Nicholas Theodore, Daniel D. Cavalcanti, Robert F. Spetzler, and Mark C. Preul
Angiopoietin-like 4 (ANGPTL4) gene polymorphisms and risk of brain arteriovenous malformations, Bahar Mikhak, Shantel Weinsheimer, Ludmila Pawlikowska, Annie Poon, Pui-Yan Kwok, Michael T. Lawton, Yongmei Chen, Jonathan G. Zaroff, Stephen Sidney, Charles E. McCulloch, William L. Young, and Helen Kim
Surgical Approaches to Intramedullary Cavernous Malformations of the Spinal Cord, Alim P. Mitha, Jay D. Turner, and Robert F. Spetzler
The financial imperative of physicians to control demand of laboratory testing, R. K.J. Murphy, S. McHugh, N. O'Farrell, B. Dougherty, A. Sheikh, M. Corrigan, and A. D.K. Hill
Acute Transient Cortical Blindness Due to Seizure Following Cerebral Angiography, C. Benjamin Newman, Courtney M. Schusse, Yin C. Hu, Cameron G. McDougall, and Felipe C. Albuquerque
The Surgical Management of Parkinson's Disease, Francisco A. Ponce and Andres M. Lozano
Decompressive craniectomy: Technical note, T. M. Quinn, J. J. Taylor, J. A. Magarik, E. Vought, M. S. Kindy, and D. B. Ellegala
Flash fluorescence with indocyanine green videoangiography to identify the recipient artery for bypass with distal middle cerebral artery aneurysms: operative technique, Ana Rodríguez-Hernández and Michael T. Lawton
Aneurysms associated with non-moyamoya collateral arterial networks: report of three cases and review of literature, Ana Rodríguez-Hernández, Daniel C. Lu, Susanna Miric, and Michael T. Lawton
Segmental anatomy of cerebellar arteries: a proposed nomenclature. Laboratory investigation, Ana Rodríguez-Hernández, Albert L. Rhoton, and Michael T. Lawton
Normal pressure hydrocephalus, Gail Rosseau
Pituitary tumors and transsphenoidal surgery, Gail L. Rosseau
Intraoperative confocal microscopy for brain tumors: a feasibility analysis in humans., Nader Sanai, Jennifer M Eschbacher, Guido Hattendorf, Stephen W Coons, Mark C Preul, Kris A Smith, Peter Nakaji, and Robert F Spetzler
Intraoperative Confocal Microscopy in the Visualization of 5-Aminolevulinic Acid Fluorescence in Low-Grade Gliomas: Clinical Article, Nader Sanai, Laura A. Snyder, Norissa J. Honea, Stephen W. Coons, Jennifer M. Eschbacher, Kris A. Smith, and Robert F. Spetzler
Neurosurgical treatment of trigeminal neuralgia, Sophia F. Shakur, Anita Bhansali, Ali Y. Mian, and Gail L. Rosseau
Large Hemangiopericytoma Associated With Arteriovenous Malformations and Dural Arteriovenous Fistulae, M. Yashar S. Kalani, Nikolay L. Martirosyan, Jennifer M. Eschbacher, Peter Nakaji, Felipe C. Albuquerque, and Robert F. Spetzler
Current Indications for Indocyanine Green Angiography, Laura A. Snyder and Robert F. Spetzler
Ossification of the Ligamentum Flavum (Olf): An Increasing Cause of Cervical Myelopathy, Volker K.H. Sonntag
A 3-Tier Classification of Cerebral Arteriovenous Malformations, Robert F. Spetzler and Francisco A. Ponce
The Evolution of Neurosurgical Instrumentation, Robert F. Spetzler and Rodney Samuelson
Neurons in the Human Hippocampus and Amygdala Respond to Both Low- and High-Level Image Properties, Peter N. Steinmetz, Elaine Cabrales, Michael S. Wilson, Christopher P. Baker, Christopher K. Thorp, Kris A Smith, and David M. Treiman
Giant intracranial aneurysms: evolution of management in a contemporary surgical series, Michael E. Sughrue, David Saloner, Vitaliy L. Rayz, and Michael T. Lawton
Elevated BNP is associated with vasospasm-independent cerebral infarction following aneurysmal subarachnoid hemorrhage, Pam R. Taub, Jeremy D. Fields, Alan H.B. Wu, Jacob C. Miss, Michael T. Lawton, Wade S. Smith, William L. Young, Jonathan G. Zaroff, and Nerissa U. Ko
Progressive vertebral body osteolysis after cervical disc arthroplasty., Luis M Tumialán and Wayne M Gluf
Arthroscopic techniques in minimally invasive spine surgery: closure of the lumbar fascia: surgical technique., Luis M Tumialán, Ryan Ponton, and Anthony I Riccio
Supracerebellar infratentorial endoscopically controlled resection of pineal lesions: case series and operative technique., Timothy Uschold, Adib A Abla, David J Fusco, Ruth E Bristol, and Peter Nakaji
Gene expression profiling of blood in brain arteriovenous malformation patients, Shantel M. Weinsheimer, Huichun Xu, Achal S. Achrol, Boryana Stamova, Charles E. McCulloch, Ludmila Pawlikowska, Yingfang Tian, Nerissa U. Ko, Michael T. Lawton, Gary K. Steinberg, Steven D. Chang, Glen Jickling, Bradley P. Ander, Helen Kim, Frank R. Sharp, and William L. Young
Terminal ventriculostomy as an adjuvant treatment of complex syringomyelia: a case report and review of the literature., David A Wilson, David J Fusco, and Harold L Rekate
Delayed subarachnoid hemorrhage following failed odontoid screw fixation., David A Wilson, David J Fusco, and Nicholas Theodore
Submissions from 2010
Comparison of dural grafts in Chiari decompression surgery: Review of the literature., Adib A Abla, Timothy Link, David J Fusco, David A Wilson, and Volker K H Sonntag
Coiling Versus Clipping for Posterior Communicating Artery Aneurysms Associated With Oculomotor Nerve Palsy: Only Time Will Tell, Felipe C. Albuquerque
Stroke in the "Real World", Felipe C. Albuquerque
Long-term outcome in the repair of spinal cord perimedullary arteriovenous fistulas, L. Antonietti, S. A. Sheth, V. V. Halbach, R. T. Higashida, C. F. Dowd, M. T. Lawton, J. D. English, and Steven W. Hetts
Initial audit of a basic and emergency neurosurgical training program in rural Tanzania, Jonah E. Attebery, Emanuel Mayegga, Robert G. Louis, Rachel Chard, Abednego Kinasha, and Dilantha B. Ellegala
The evolution of the treatment of traumatic cerebrovascular injury during wartime., Randy S Bell, Robert D Ecker, Meryl A Severson, John E Wanebo, Benjamin Crandall, and Rocco A Armonda
Wartime traumatic aneurysms: acute presentation, diagnosis, and multimodal treatment of 64 craniocervical arterial injuries., Randy S Bell, Alexander H Vo, Ryan Roberts, John E Wanebo, and Rocco A Armonda
Computed tomographic angiography in evaluation of superficial temporal to middle cerebral artery bypass., David A Besachio, Jordan I Ziegler, Timothy D Duncan, and John S Wanebo
Stabilization of the Atlantoaxial Joint With C1-C3 Lateral Mass Screw Constructs: Biomechanical Comparison With Standard Technique, Leonardo B.C. Brasiliense, Bruno C.R. Lazaro, Phillip M. Reyes, Douglas Fox, Volker K.H. Sonntag, and Neil R. Crawford
Anterolateral C1-C2 Transarticular Fixation for Atlantoaxial Arthrodesis: Landmarks Working Area and Angles of Approach, Daniel D. Cavalcanti, Abhishek Agrawal, Ulises Garcia-Gonzalez, Neil R. Crawford, Paulo L.M.S. Tavares, Nicholas Theodore, Volker K.H. Sonntag, and Mark C. Preul
The Anatomy of the Callosomarginal Artery: Applications to Microsurgery and Endovascular Surgery, Daniel D. Cavalcanti, Felipe C. Albuquerque, Benjamin F. Silva, Robert F. Spetzler, and Mark C. Preul