The neural basis of attaining conscious awareness of sad mood.

Document Type

Article

Abstract

The neural processes associated with becoming aware of sad mood are not fully understood. We examined the dynamic process of becoming aware of sad mood and recovery from sad mood. Sixteen healthy subjects underwent fMRI while participating in a sadness induction task designed to allow for variable mood induction times. Individualized regressors linearly modeled the time periods during the attainment of self-reported sad and baseline "neutral" mood states, and the validity of the linearity assumption was further tested using independent component analysis. During sadness induction the dorsomedial and ventrolateral prefrontal cortices, and anterior insula exhibited a linear increase in the blood oxygen level-dependent (BOLD) signal until subjects became aware of a sad mood and then a subsequent linear decrease as subjects transitioned from sadness back to the non-sadness baseline condition. These findings extend understanding of the neural basis of conscious emotional experience.

Medical Subject Headings

Adolescent; Adult; Affect; Awareness; Brain; Brain Mapping; Cerebrovascular Circulation; Female; Humans; Linear Models; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Oxygen; Self Report; Young Adult

Publication Date

9-1-2015

Publication Title

Brain Imaging Behav

ISSN

1931-7565

Volume

9

Issue

3

First Page

574

Last Page

587

PubMed ID

25234799

Digital Object Identifier (DOI)

10.1007/s11682-014-9318-8

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