Endoscopic Intraventricular Biopsy of Infundibular Langerhans Cell Histiocytosis: Case Report

Department

neurosurgery

Document Type

Article

Abstract

OBJECTIVE: Surgical biopsy of isolated infundibular lesions is indicated in patients who are symptomatic or whose imaging suggests a treatable lesion. Early therapy can prevent irreversible neurological or endocrinological damage and, potentially, metastasis. These considerations justify the small risk associated with surgery. CLINICAL PRESENTATION: A 5-year-old boy presented with diabetes insipidus and an enhancing lesion of the pituitary stalk without evidence of extracranial disease. INTERVENTION: The lesion was biopsied via an endoscopic intraventricular approach without complications. Pathological examination revealed Langerhans cell histiocytosis. CONCLUSION: Endoscopic intraventricular biopsy can be considered as a less invasive alternative to craniotomy in patients with infundibular lesions protruding superiorly into the third ventricle. Copyright © by the Congress of Neurological Surgeons.

Publication Date

2009

Publication Title

Neurosurgery

ISSN

0148-396X

Volume

65

Issue

1

First Page

E214

Last Page

E215

Digital Object Identifier (DOI)

10.1227/01.NEU.0000346650.68447.95

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