The Barrow Neurological Institute is proud of its reputation as a medical research facility and is home to some of the most sophisticated research programs outside of an academic setting in the Southwestern United States. Researchers in the Barrow Neurosurgery Research Center are devoted to learning more about the causes of and treatments for a wide range of disorders, such as stroke, aneurysms, spinal cord injury, and hydrocephalus. Our research has led to treatments that are being used around the world. Within the Department are neurosurgeons who subspecialize in cerebrovascular and skull base, functional and stereotactic, pediatric, spine, tumor, and endovascular neurosurgery.

Physicians, scientists, and expert clinical staff come together with a commitment to developing new techniques for the prevention, diagnosis, treatment, and rehabilitation of neurological illnesses and injuries. The leadership of internationally respected physicians keeps Barrow at the forefront of neuroscience. The compassionate expertise of its extensive staff of nurses, technologists, therapists and support personnel is evident in every aspect of care provided.

Our mission is to advance the knowledge and practice of medicine in neuroscience through basic and clinical research, education of medical professionals, and innovation in clinical techniques and technology.

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Submissions from 2014

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Angioglioma misdiagnosed as encephalomalacia on magnetic resonance imaging for over a decade, Shinjini Kundu, Lea Alhilali, Lananh Nguyen, and Saeed Fakhran

Distinguishing the Tremor of Parkinson's Disease From Essential Tremor: Finger Displacement, Abraham N. Lieberman, Rohit Dhall, Sara Dhanani, Naomi Salins, Arshia Sadreddin, Guillermo Moguel-Cobos, Di Pan, Anthony Santiago, George Prigatano, Narayanan Krishnamurthi, and Alexander Tröster

Finger Displacement in Parkinson Disease: Up Down Sideways, Abraham N. Lieberman, Rohit Dhall, Naomi Salins, Arshia Sadreddin, Guillermo Moguel-Cobos, John Karis, and Narayanan Krishnamurthi

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Current status of endovascular procedures in management of ischemic stroke in China, Li-Ping Liu, Lawrence K. Wong, David Z. Wang, and Zhong-Rong Miao

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Risk assessment of deep-vein thrombosis after acute stroke: a prospective study using clinical factors, Li-Ping Liu, Hua-Guang Zheng, David Z. Wang, Yi-Long Wang, Mohammed Hussain, Hai-Xin Sun, An-Xin Wang, Xing-Quan Zhao, Ke-Hui Dong, Chun-Xue Wang, Wen He, Bin Ning, and Yong-Jun Wang

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Screening for early detection of parkinsonism using a self-administered questionnaire: a cross-sectional epidemiologic study, Jessica I. Lundin, Harvey Checkoway, Susan R. Criswell, Angela J. Hobson, Rachel C. Harris, Laura M. Swisher, Bradley A. Evanoff, and Brad A. Racette

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Formulations of hormone therapy and risk of Parkinson's disease, Jessica I. Lundin, Thanh G. Ton, Andrea Z. LaCroix, W T. Longstreth, Gary M. Franklin, Phillip D. Swanson, Terri Smith-Weller, Brad A. Racette, and Harvey Checkoway

Associations between estimated glomerular filtration rate and stroke outcomes in diabetic versus nondiabetic patients., Yang Luo, Xianwei Wang, Kunihiro Matsushita, Chunxue Wang, Xingquan Zhao, Bo Hu, Liping Liu, Hao Li, Gaifen Liu, Qian Jia, Yilong Wang, and Yongjun Wang

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Biochemical assessment of precuneus and posterior cingulate gyrus in the context of brain aging and Alzheimer's disease, Chera L. Maarouf, Tyler A. Kokjohn, Douglas G. Walker, Charisse M. Whiteside, Walter M. Kalback, Alexis Whetzel, Lucia I. Sue, Geidy Serrano, Sandra A. Jacobson, Marwan N. Sabbagh, Eric M. Reiman, Thomas G. Beach, and Alex E. Roher

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A cellular model of amyloid precursor protein processing and amyloid-β peptide production, Mi Mi P. Macias, Amanda M. Gonzales, Ashley L. Siniard, Aaron W. Walker, Jason J. Corneveaux, Matthew J. Huentelman, Marwan N. Sabbagh, and Boris Decourt

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Comparative analysis of the Alzheimer Questionnaire (AQ) with the CDR sum of boxes, MoCA, and MMSE, Michael Malek-Ahmadi, Kathryn Davis, Christine M. Belden, and Marwan N. Sabbagh

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Treatment options for atypical optic neuritis, Amina Malik, Maryam Ahmed, and Karl Golnik

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Cerebrospinal fluid diversion procedures in the treatment of patients with idiopathic intracranial hypertension, Amina Malik and Karl Golnik

Head trauma and in vivo measures of amyloid and neurodegeneration in a population-based study, Michelle M. Mielke, Rodolfo Savica, Heather J. Wiste, Stephen D. Weigand, Prashanthi Vemuri, David S. Knopman, Val J. Lowe, Rosebud O. Roberts, Mary M. Machulda, Yonas E. Geda, Ronald C. Petersen, and Clifford R. Jack

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Optic nerve cyst-like formation presenting as a delayed complication of optic nerve sheath fenestration, Syeda Maryam Naqvi, Chris Thiagarajah, Karl Golnik, Andrew Lee, Robert Kersten, and Jeffrey Nerad

An Extent of Resection Threshold for Recurrent Glioblastoma and its Risk for Neurological Morbidity: Clinical Article, Mark E. Oppenlander, Andrew B. Wolf, Laura A. Snyder, Robert Bina, Jeffrey R. Wilson, Stephen W. Coons, Lynn S. Ashby, David Brachman, Peter Nakaji, Randall W. Porter, Kris A. Smith, Robert F. Spetzler, and Nader Sanai

Recursive Partitioning Analysis of Prognostic Variables in Newly Diagnosed Anaplastic Oligodendroglial Tumors, Katherine S. Panageas, Anne S. Reiner, Fabio M. Iwamotoa, Timothy F. Cloughesy, Kenneth D. Aldape, Andreana L. Riverab, April F. Eichler, David N. Louis, Nina A. Paleologosc, Barbara J. Fisher, Lynn S. Ashby, J. Gregory Cairncross, Gloria B. Roldán Urgoiti, Patrick Y. Wen, Keith L. Ligon, David Schiff, H. Ian Robins, Brandon G. Rocqued, Marc C. Chamberlain, and et al.

Use of statin during hospitalization improves the outcome after intracerebral hemorrhage., Yue-Song Pan, Jing Jing, Yi-Long Wang, Xing-Quan Zhao, Bo Song, Wen-Juan Wang, David Z. Wang, Gai-Fen Liu, Li-Ping Liu, Chun-Xue Wang, and Yong-Jun Wang

Hypothyroidism and risk of mild cognitive impairment in elderly persons a population-based study, Ajay K. Parsaik, Balwinder Singh, Rosebud O. Roberts, Shane Pankratz, Kelly K. Edwards, Yonas E. Geda, Hossein Gharib, Bradley F. Boeve, David S. Knopman, and Ronald C. Petersen

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Manganism in the 21st century: the Hanninen lecture, Brad A. Racette

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Supply and demand analysis of the current and future US neurology workforce, Brad A. Racette, David M. Holtzman, Timothy M. Dall, and Oksana Drogan

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Florbetaben for PET Imaging of Beta-Amyloid Plaques in the Brain, Danielle Richards and Marwan N. Sabbagh

Diabetes and elevated hemoglobin a1c levels are associated with brain hypometabolism but not amyloid accumulation, Rosebud O. Roberts, David S. Knopman, Ruth H. Cha, Michelle M. Mielke, V. Shane Pankratz, Bradley F. Boeve, Kejal Kantarci, Yonas E. Geda, Clifford R. Jack, Ronald C. Petersen, and Val J. Lowe

Association of diabetes with amnestic and nonamnestic mild cognitive impairment, Rosebud O. Roberts, David S. Knopman, Yonas E. Geda, Ruth H. Cha, V. Shane Pankratz, Luke Baertlein, Bradley F. Boeve, Eric G. Tangalos, Robert J. Ivnik, Michelle M. Mielke, and Ronald C. Petersen

Higher risk of progression to dementia in mild cognitive impairment cases who revert to normal, Rosebud O. Roberts, David S. Knopman, Michelle M. Mielke, Ruth H. Cha, V. Shane Pankratz, Teresa J.H. Christianson, Yonas E. Geda, Bradley F. Boeve, Robert J. Ivnik, Eric G. Tangalos, Walter A. Rocca, and Ronald C. Petersen

Association of type 2 diabetes with brain atrophy and cognitive impairment, Rosebud O. Roberts, David S. Knopman, Scott A. Przybelski, Michelle M. Mielke, Kejal Kantarci, Gregory M. Preboske, Matthew L. Senjem, Vernon S. Pankratz, Yonas E. Geda, Bradley F. Boeve, Robert J. Ivnik, Walter A. Rocca, Ronald C. Petersen, and Clifford R. Jack

Neuropathological and biochemical assessments of an Alzheimer’s disease patient treated with the γ-secretase inhibitor semagacestat, Alex E. Roher, Chera L. Maarouf, Tyler A. Kokjohn, Charisse M. Whiteside, Walter M. Kalback, Geidy Serrano, Christine Belden, Carolyn Liebsack, Sandra A. Jacobson, Marwan N. Sabbagh, and Thomas G. Beach

Modeling glial contributions to seizures and epileptogenesis: cation-chloride cotransporters in Drosophila melanogaster., Zeid M Rusan, Olivia Kingsford, and Mark A Tanouye

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Two phase 3 trials of Bapineuzumab in mild-to-moderate Alzheimer's disease, Stephen Salloway, Reisa Sperling, Nick C. Fox, Kaj Blennow, William Klunk, Murray Raskind, Marwan Sabbagh, Lawrence S. Honig, Anton P. Porsteinsson, Steven Ferris, Marcel Reichert, Nzeera Ketter, Bijan Nejadnik, Volkmar Guenzler, Maja Miloslavsky, Daniel Wang, Yuan Lu, Julia Lull, Iulia Cristina Tudor, Enchi Liu, Michael Grundman, Eric Yuen, Ronald Black, and H. Robert Brashear

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Positive florbetapir PET amyloid imaging in a subject with frequent cortical neuritic plaques and frontotemporal lobar degeneration with TDP43-positive inclusions, Geidy E. Serrano, Marwan N. Sabbagh, Lucia I. Sue, Jose A. Hidalgo, Julie A. Schneider, Barry J. Bedell, Vivianna M. Van Deerlin, Eunran Suh, Haruhiko Akiyama, Abhinay D. Joshi, Michael J. Pontecorvo, Mark A. Mintun, and Thomas G. Beach

Pathologic and Imaging Correlates of Cognitive Deficits in Multiple Sclerosis: Changing the Paradigm of Diagnosis and Prognosis, Jiong Shi, Leslie C. Baxter, and Sandra M. Kuniyoshi

Cognitive Impairment in Neurological Diseases: Lessons From Apolipoprotein E, Jiong Shi, Pengcheng Han, and Sandra M. Kuniyoshi

Essential Tremor in the Elderly and Risk for Dementia, Holly A. Shill, Joseph G. Hentz, Sandra A. Jacobson, Christine Belden, Marwan N. Sabbagh, Thomas G. Beach, Erika Driver-Dunckley, and Charles H. Adler

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PET imaging of amyloid with Florbetapir F 18 and PET imaging of dopamine degeneration with 18F-AV-133 (florbenazine) in patients with Alzheimer's disease and Lewy body disorders, Andrew Siderowf, Michael J. Pontecorvo, Holly A. Shill, Mark A. Mintun, Anupa Arora, Abhinay D. Joshi, Ming Lu, Charles H. Adler, Douglas Galasko, Carolyn Liebsack, Daniel M. Skovronsky, and Marwan N. Sabbagh

A prospective study of chronic obstructive pulmonary disease and the risk for mild cognitive impairment, Balwinder Singh, Michelle M. Mielke, Ajay K. Parsaik, Ruth H. Cha, Rosebud O. Roberts, Paul D. Scanlon, Yonas E. Geda, Teresa J. Christianson, V. Shane Pankratz, and Ronald C. Petersen

The Impact of Extent of Resection on Malignant Transformation of Pure Oligodendrogliomas: Clinical Article, Laura A. Snyder, Andrew B. Wolf, Mark E. Oppenlander, Robert Bina, Jeffrey R. Wilson, Lynn S. Ashby, David Brachman, Stephen W. Coons, Robert F. Spetzler, and Nader Sanai

Interleukin-7 Expression and its Effect on Natural Killer Cells in Patients With Multiple Sclerosis, Ning Su, Samuel X. Shi, Xiaodong Zhu, Aimee Borazanci, Fu-Dong Shi, and Yan Gan

Cx3Cr1 Deficiency Suppresses Activation and Neurotoxicity of Microglia/Macrophage in Experimental Ischemic Stroke, Zhiwei Tang, Yan Gan, Qiang Liu, Jun Xiang Yin, Qingwei Liu, Jiong Shi, and Fu-Dong Shi

A Solitary Hemangioblastoma Located on the Trochlear Nerve, Zhiwei Tang, Chongqian Wang, and Jiong Shi

Differences in Cerebrospinal Fluid Biomarkers between Clinically Diagnosed Idiopathic Normal Pressure Hydrocephalus and Alzheimer's Disease, Andrew Tsai, Michael Malek-Ahmadi, Vickram Kahlon, and Marwan N. Sabbagh

Early and persistent 'extreme delta brush' in a patient with anti-NMDA receptor encephalitis, Stephen VanHaerents, Alexandra Stillman, Violiza Inoa, David Eric Searls, and Susan T. Herman

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A rare sequence variant in intron 1 of THAP1 is associated with primary dystonia, Satya R. Vemula, Jianfeng Xiao, Yu Zhao, Robert W. Bastian, Joel S. Perlmutter, Brad A. Racette, Randal C. Paniello, Zbigniew K. Wszolek, Ryan J. Uitti, Jay A. Van Gerpen, Peter Hedera, Daniel D. Truong, Andrew Blitzer, Monika Rudzińska, Dragana Momčilović, Hyder A. Jinnah, Karen Frei, Ronald F. Pfeiffer, and Mark S. LeDoux

Association of lifetime intellectual enrichment with cognitive decline in the older population, Prashanthi Vemuri, Timothy G. Lesnick, Scott A. Przybelski, Mary Machulda, David S. Knopman, Michelle M. Mielke, Rosebud O. Roberts, Yonas E. Geda, Walter A. Rocca, Ronald C. Petersen, and Clifford R. Jack

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Anticoagulation-related reduction of first-ever stroke severity in Chinese patients with atrial fibrillation, Chunjuan Wang, Yilong Wang, Chunxue Wang, Xingquan Zhao, Liping Liu, Gaifen Liu, David Z. Wang, Hao Li, and Yongjun Wang

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Significant underuse of warfarin in patients with nonvalvular atrial fibrillation: results from the China national stroke registry, Chunjuan Wang, Zhonghua Yang, Chunxue Wang, Yilong Wang, Xingquan Zhao, Liping Liu, David Z. Wang, Hao Li, and Yongjun Wang

Practical steps for implementing quality measurement in practice., David Z. Wang, Becky A Schierman, Eric M Cheng, Amy E Sanders, and Richard M Dubinsky

Association between estimated glomerular filtration rate and clinical outcomes in patients with acute ischaemic stroke: results from China National Stroke Registry., Xianwei Wang, Yilong Wang, Chunxue Wang, Xingquan Zhao, Ying Xian, David Z. Wang, Liping Liu, Yang Luo, Gaifen Liu, and Yongjun Wang

Recurrent stroke was associated with poor quality of life in patients with transient ischemic attack or minor stroke: finding from the CHANCE trial., Yi-Long Wang, Yue-Song Pan, Xing-Quan Zhao, David Z. Wang, S Claiborne Johnston, Li-Ping Liu, Xia Meng, An-Xin Wang, Chun-Xue Wang, and Yong-Jun Wang

Concussion 101: The Current State of Concussion Education Programs, Richard W. Williamson, Deborah Gerhardstein, Javier F. Cardenas, Daniel B. Michael, Nicholas Theodore, and Natalie Rosseauk

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Disparities in deep brain stimulation surgery among insured elders with Parkinson disease, Allison W. Willis, Mario Schootman, Nathan Kung, Xiao-Yu Wang, Joel S. Perlmutter, and Brad A. Racette

Hypercaloric Enteral Nutrition in Patients With Amyotrophic Lateral Sclerosis: A Randomised Double-Blind Placebo-Controlled Phase 2 Trial, Anne Marie Wills, Jane Hubbard, Eric A. Macklin, Jonathan Glass, Rup Tandan, Ericka P. Simpson, Benjamin Brooks, Deborah Gelinas, Hiroshi Mitsumoto, Tahseen Mozaffar, Gregory P. Hanes, Shafeeq S. Ladha, Terry Heiman-Patterson, Jonathan Katz, Jau Shin Lou, Katy Mahoney, Daniela Grasso, Robert Lawson, Hong Yu, and et al.

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Sparse and Distributed Coding of Episodic Memory in Neurons of the Human Hippocampus, John T. Wixted, Larry R. Squire, Yoonhee Jang, Megan H. Papesh, Stephen D. Goldinger, Joel R. Kuhn, Kris A. Smith, David M. Treiman, and Peter N. Steinmetz

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Evaluation of tentorial length and angle in sleep-wake disturbances after mild traumatic brain injury, Karl Yaeger, Lea Alhilali, and Saeed Fakhran

Pertussis Toxin Modulates Microglia and T Cell Profile to Protect Experimental Autoimmune Encephalomyelitis, Jun Xiang Yin, Zhiwei Tang, Yan Gan, Lejun Li, Fu-Dong Shi, Stephen Coons, and Jiong Shi

Association of Amyloid Burden Brain Atrophy and Memory Deficits in Aged Apolipoprotein Epsilon-4 Mice, Junxiang Yin, Gregory H. Turner, Stephen W. Coons, Marwan Maalouf, Eric M. Reiman, and Jiong Shi

Submissions from 2013

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Neurodegeneration: The first IBRO-Middle east neuroscience conference, Abdu Adem, Omar El Agnaf, and Marwan N. Sabbagh

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Evaluation of a limited three-slice head CT protocol for monitoring patients with ventriculoperitoneal shunts, Lea M. Alhilali, Andreea C. Dohatcu, and Saeed Fakhran

Evaluation of the intervertebral disk angle for the assessment of anterior cervical diskoligamentous injury., L M Alhilali and S Fakhran

Estrogen receptor mutation in a girl with primary amenorrhea., M Asadi, S Ghafouri-Fard, D Zare-Abdollahi, A Ebrahim-Habibi, and N Matin

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Phase III Randomized Trial Comparing the Efficacy of Cediranib as Monotherapy and in Combination With Lomustine Versus Lomustine Alone in Patients With Recurrent Glioblastoma, Tracy T. Batchelor, Paul Mulholland, Bart Neyns, L. Burt Nabors, Mario Campone, Antje Wick, Warren Mason, Tom Mikkelsen, Surasak Phuphanich, Lynn S. Ashby, John DeGroot, Rao Gattamaneni, Lawrence Cher, Mark Rosenthal, Franz Payer, Juliane M. Jürgensmeier, Rakesh K. Jain, A. Gregory Sorensen, John Xu, and et al.

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Submandibular gland biopsy for the diagnosis of parkinson disease, Thomas G. Beach, Charles H. Adler, Brittany N. Dugger, Geidy Serrano, Jose Hidalgo, Jonette Henry-Watson, Holly A. Shill, Lucia I. Sue, Marwan N. Sabbagh, and Haruhiko Akiyama

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Successes and failures for drugs in late-stage development for alzheimer's disease, Camryn Berk and Marwan N. Sabbagh

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Clinical reasoning: an 85-year-old man with paresthesias and an unsteady gait, Aaron L. Berkowitz, Ruchira M. Jha, Joshua P. Klein, and Anthony A. Amato

The Established Status Epilepticus Trial 2013, Thomas Bleck, Hannah Cock, James Chamberlain, James Cloyd, Jason Connor, Jordan Elm, Nathan Fountain, Elizabeth Jones, Daniel Lowenstein, Shlomo Shinnar, Robert Silbergleit, David M. Treiman, Eugen Trinka, and Jaideep Kapur

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Clinicopathologic correlations in 172 cases of rapid eye movement sleep behavior disorder with or without a coexisting neurologic disorder, B. F. Boeve, M. H. Silber, T. J. Ferman, S. C. Lin, E. E. Benarroch, A. M. Schmeichel, J. E. Ahlskog, R. J. Caselli, S. Jacobson, M. Sabbagh, C. Adler, B. Woodruff, T. G. Beach, A. Iranzo, E. Gelpi, J. Santamaria, E. Tolosa, C. Singer, D. C. Mash, C. Luca, I. Arnulf, C. Duyckaerts, C. H. Schenck, M. W. Mahowald, Y. Dauvilliers, N. R. Graff-Radford, Z. K. Wszolek, J. E. Parisi, B. Dugger, M. E. Murray, and D. W. Dickson

Risk factors for dementia with Lewy bodies A case-control study, Brendon P. Boot, Carolyn F. Orr, J. Eric Ahlskog, Tanis J. Ferman, Rosebud Roberts, Vernon S. Pankratz, Dennis W. Dickson, Joseph Parisi, Jeremiah A. Aakre, Yonas E. Geda, David S. Knopman, Ronald C. Petersen, and Bradley F. Boeve

Hypersexuality in Dementia: A Case Presentation With Discussion, Anna D. Burke, Roy Yaari, Pierre N. Tariot, Adam S. Fleisher, Geri R. Hall, and Helle Brand

The Threat of Behavioral Changes in Dementia, Anna D. Burke, Roy Yaari, Pierre N. Tariot, Geri R. Hall, Jan Dougherty, Helle Brand, and Adam S. Fleisher

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The clinical problem of neuropsychiatric signs and symptoms in dementia, Anna Burke, Geri Hall, and Pierre N. Tariot

Managing common complex symptomatic epilepsies: Tumors and trauma, Jorge G. Burneo, Joseph I. Sirven, Lily Wong Kiesel, Charles J. Vecht, Lara Jehi, Steve S. Chung, Joon Uhm, Jeffrey M. Politsky, Edward F. Chang, Aatif M. Husain, William O. Tatum, Kimford J. Meador, Katherine Noe, Dale C. Hesdorffer, Susan T. Herman, Samuel Wiebe, Jerome Engel, Sara Schrader, Karen L. Parko, March A. Dichter, Patrick Kwan, Eric Kossoff, and Michael R. Sperling

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Alzheimer disease periventricular white matter lesions exhibit specific proteomic profile alterations, Eduardo M. Castaño, Chera L. Maarouf, Terence Wu, Maria Celeste Leal, Charisse M. Whiteside, Lih Fen Lue, Tyler A. Kokjohn, Marwan N. Sabbagh, Thomas G. Beach, and Alex E. Roher

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High-Dose Donepezil (23 mg/day) for the Treatment of Moderate and Severe Alzheimer's Disease: Drug Profile and Clinical Guidelines, Jeffrey L. Cummings, David Geldmacher, Martin Farlow, Marwan Sabbagh, Daniel Christensen, and Peter Betz

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BACE1 levels by APOE genotype in non-demented and Alzheimer's post-mortem brains, Boris Decourt, Amanda Gonzales, Thomas G. Beach, Michael Malek-Ahmadi, Aaron Walker, Lucia Sue, Douglas G. Walker, and Marwan N. Sabbagh

Recent Perspectives on APP, Secretases, Endosomal Pathways and How they Influence Alzheimer's Related Pathological Changes in Down Syndrome, Boris Decourt, William Mobley, Eric Reiman, Raj Jatin Shah, and Marwan N. Sabbagh

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Can platelet BACE1 levels be used as a biomarker for Alzheimer's disease? Proof-of-concept study, Boris Decourt, Aaron Walker, Amanda Gonzales, Michael Malek-Ahmadi, Carolyn Liesback, Kathryn J. Davis, Christine M. Belden, Sandra A. Jacobson, and Marwan N. Sabbagh

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Differential processing of amyloid precursor protein in brain and in peripheral blood leukocytes, Elaine Delvaux, Karen Bentley, Victoria Stubbs, Marwan Sabbagh, and Paul D. Coleman

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Mu-opioid receptor A118G polymorphism in healthy volunteers affects hypothalamic-pituitary-adrenal axis adrenocorticotropic hormone stress response to metyrapone, Elizabeth Ducat, Brenda Ray, Gavin Bart, Yoshie Umemura, Jack Varon, Ann Ho, and Mary Jeanne Kreek

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Symptomatic white matter changes in mild traumatic brain injury resemble pathologic features of early Alzheimer dementia, Saeed Fakhran, Karl Yaeger, and Lea Alhilali

Yield of CT angiography and contrast-enhanced MR imaging in patients with dizziness., S Fakhran, L Alhilali, and B F Branstetter

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Effects of donepezil 23 mg on Severe Impairment Battery domains in patients with moderate to severe Alzheimer's disease: Evaluating the impact of baseline severity, Steven Ferris, Jeffrey Cummings, Daniel Christensen, Rachelle Doody, Martin Farlow, Marwan Sabbagh, Liang Liu, Joan MacKell, and Randi Fain

Neuro-otology. Preface., Terry D Fife

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Posttraumatic Vertigo and Dizziness, Terry D. Fife and Christopher Giza

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Apolipoprotein E ε4 and age effects on florbetapir positron emission tomography in healthy aging and Alzheimer disease, Adam S. Fleisher, Kewei Chen, Xiaofen Liu, Napatkamon Ayutyanont, Auttawut Roontiva, Pradeep Thiyyagura, Hillary Protas, Abhinay D. Joshi, Marwan Sabbagh, Carl H. Sadowsky, Reisa A. Sperling, Christopher M. Clark, Mark A. Mintun, Michael J. Pontecorvo, R. Edward Coleman, P. M. Doraiswamy, Keith A. Johnson, Alan P. Carpenter, Daniel M. Skovronsky, and Eric M. Reiman

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Antiepileptic drug treatment: new drugs and new strategies, Jacqueline A. French and Deana M. Gazzola

Caloric intake, aging, and mild cognitive impairment: A population-based study, Yonas E. Geda, Marion Ragossnig, Lewis A. Roberts, Rosebud O. Roberts, V. Shane Pankratz, Teresa J.H. Christianson, Michelle M. Mielke, James A. Levine, Bradley F. Boeve, Ondřej Sochor, Eric G. Tangalos, David S. Knopman, and Ronald C. Petersen

Neuropsychiatric symptoms in Alzheimer's disease: Past progress and anticipation of the future, Yonas E. Geda, Lon S. Schneider, Laura N. Gitlin, David S. Miller, Gwenn S. Smith, Joanne Bell, Jovier Evans, Michael Lee, Anton Porsteinsson, Krista L. Lanctôt, Paul B. Rosenberg, David L. Sultzer, Paul T. Francis, Henry Brodaty, Prasad P. Padala, Chiadikaobi U. Onyike, Luis Agüera Ortiz, Sonia Ancoli-Israel, Donald L. Bliwise, Jennifer L. Martin, Michael V. Vitiello, Kristine Yaffe, Phyllis C. Zee, Nathan Herrmann, Robert A. Sweet, Clive Ballard, Ni A. Khin, Cara Alfaro, Patrick S. Murray, Susan Schultz, and Constantine G. Lyketsos

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Neuro-ophthalmology around the world, Karl C. Golnik

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Reply: Intentional extreme anisometropic pseudophakic monovision, Karl C. Golnik

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Parkinson disease is not associated with C9ORF72 repeat expansions, Matthew B. Harms, Drexel Neumann, Bruno A. Benitez, Breanna Cooper, David Carrell, Brad A. Racette, Joel S. Perlmutter, Alison Goate, and Carlos Cruchaga

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SMG1 identified as a regulator of Parkinson's disease-associated alpha-synuclein through siRNA screening., Adrienne Henderson-Smith, Donald Chow, Bessie Meechoovet, Meraj Aziz, Sandra A. Jacobson, Holly A. Shill, Marwan N. Sabbagh, John N. Caviness, Charles H. Adler, Erika D. Driver-Dunckley, Thomas G. Beach, Hongwei Yin, and Travis Dunckley

American clinical neurophysiology society's standardized critical care EEG terminology: 2012 version, L. J. Hirsch, S. M. Laroche, N. Gaspard, E. Gerard, A. Svoronos, S. T. Herman, R. Mani, H. Arif, N. Jette, Y. Minazad, J. F. Kerrigan, P. Vespa, S. Hantus, J. Claassen, G. B. Young, E. So, P. W. Kaplan, M. R. Nuwer, N. B. Fountain, and F. W. Drislane

Genome-wide scan of healthy human connectome discovers SPON1 gene variant influencing dementia severity., Neda Jahanshad, Priya Rajagopalan, Xue Hua, Derrek P Hibar, Talia M Nir, Arthur W Toga, Clifford R Jack, Andrew J Saykin, Robert C Green, Michael W Weiner, Sarah E Medland, Grant W Montgomery, Narelle K Hansell, Katie L McMahon, Greig I de Zubicaray, Nicholas G Martin, Margaret J Wright, Paul M Thompson, and Marwan N. Sabbagh

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Evolution of hypoxic-ischemic injury, Ruchira M. Jha, Aaron L. Berkowitz, and Joshua P. Klein

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The isolation, differentiation, and survival in vivo of multipotent cells from the postnatal rat filum terminale, Ruchira M. Jha, Ryan Chrenek, Laura M. Magnotti, and David L. Cardozo

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The postnatal human filum terminale is a source of autologous multipotent neurospheres capable of generating motor neurons, Ruchira M. Jha, Xiaojin Liu, Ryan Chrenek, Joseph R. Madsen, and David L. Cardozo

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Florbetapir (F18-AV-45) PET to assess amyloid burden in Alzheimer's disease dementia, mild cognitive impairment, and normal aging, Keith A. Johnson, Reisa A. Sperling, Christopher M. Gidicsin, Jeremy S. Carmasin, Jacqueline E. Maye, Ralph E. Coleman, Eric M. Reiman, Marwan N. Sabbagh, Carl H. Sadowsky, Adam S. Fleisher, P. Murali Doraiswamy, Alan P. Carpenter, Christopher M. Clark, Abhinay D. Joshi, Ming Lu, Michel Grundman, Mark A. Mintun, Michel J. Pontecorvo, and Daniel M. Skovronsky

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Extrapyramidal signs by dementia severity in alzheimer disease and dementia with lewy bodies, Berneet Kaur, Danielle J. Harvey, Charles S. Decarli, Lin Zhang, Marwan N. Sabbagh, and John M. Olichney

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Residency education professionalism vignettes, Rabeea Khan, Andrew G. Lee, Karl C. Golnik, and Jaya Paranilam

Evaluation of a practical visual MRI rating scale of brain white matter hyperintensities for clinicians based on largest lesion size regardless of location., K S King, R M Peshock, M W Warren, L Alhilali, K Hulsey, R McColl, M F Weiner, C Ayers, and A Whittemore

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Neurochemical profile of dementia pugilistica, Tyler A. Kokjohn, Chera L. Maarouf, Ian D. Daugs, Jesse M. Hunter, Charisse M. Whiteside, Michael Malek-Ahmadi, Emma Rodriguez, Walter Kalback, Sandra A. Jacobson, Marwan N. Sabbagh, Thomas G. Beach, and Alex E. Roher