The Barrow Neurological Institute is proud of its reputation as a medical research facility and is home to some of the most sophisticated research programs outside of an academic setting in the Southwestern United States. Researchers in the Barrow Neurosurgery Research Center are devoted to learning more about the causes of and treatments for a wide range of disorders, such as stroke, aneurysms, spinal cord injury, and hydrocephalus. Our research has led to treatments that are being used around the world. Within the Department are neurosurgeons who subspecialize in cerebrovascular and skull base, functional and stereotactic, pediatric, spine, tumor, and endovascular neurosurgery.

Physicians, scientists, and expert clinical staff come together with a commitment to developing new techniques for the prevention, diagnosis, treatment, and rehabilitation of neurological illnesses and injuries. The leadership of internationally respected physicians keeps Barrow at the forefront of neuroscience. The compassionate expertise of its extensive staff of nurses, technologists, therapists and support personnel is evident in every aspect of care provided.

Our mission is to advance the knowledge and practice of medicine in neuroscience through basic and clinical research, education of medical professionals, and innovation in clinical techniques and technology.

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Submissions from 2014

Interleukin-7 Expression and its Effect on Natural Killer Cells in Patients With Multiple Sclerosis, Ning Su, Samuel X. Shi, Xiaodong Zhu, Aimee Borazanci, Fu-Dong Shi, and Yan Gan

Cx3Cr1 Deficiency Suppresses Activation and Neurotoxicity of Microglia/Macrophage in Experimental Ischemic Stroke, Zhiwei Tang, Yan Gan, Qiang Liu, Jun Xiang Yin, Qingwei Liu, Jiong Shi, and Fu-Dong Shi

A Solitary Hemangioblastoma Located on the Trochlear Nerve, Zhiwei Tang, Chongqian Wang, and Jiong Shi

Differences in Cerebrospinal Fluid Biomarkers between Clinically Diagnosed Idiopathic Normal Pressure Hydrocephalus and Alzheimer's Disease, Andrew Tsai, Michael Malek-Ahmadi, Vickram Kahlon, and Marwan N. Sabbagh

Early and persistent 'extreme delta brush' in a patient with anti-NMDA receptor encephalitis, Stephen VanHaerents, Alexandra Stillman, Violiza Inoa, David Eric Searls, and Susan T. Herman

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A rare sequence variant in intron 1 of THAP1 is associated with primary dystonia, Satya R. Vemula, Jianfeng Xiao, Yu Zhao, Robert W. Bastian, Joel S. Perlmutter, Brad A. Racette, Randal C. Paniello, Zbigniew K. Wszolek, Ryan J. Uitti, Jay A. Van Gerpen, Peter Hedera, Daniel D. Truong, Andrew Blitzer, Monika Rudzińska, Dragana Momčilović, Hyder A. Jinnah, Karen Frei, Ronald F. Pfeiffer, and Mark S. LeDoux

Association of lifetime intellectual enrichment with cognitive decline in the older population, Prashanthi Vemuri, Timothy G. Lesnick, Scott A. Przybelski, Mary Machulda, David S. Knopman, Michelle M. Mielke, Rosebud O. Roberts, Yonas E. Geda, Walter A. Rocca, Ronald C. Petersen, and Clifford R. Jack

Concussion 101: The Current State of Concussion Education Programs, Richard W. Williamson, Deborah Gerhardstein, Javier F. Cardenas, Daniel B. Michael, Nicholas Theodore, and Natalie Rosseauk

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Disparities in deep brain stimulation surgery among insured elders with Parkinson disease, Allison W. Willis, Mario Schootman, Nathan Kung, Xiao-Yu Wang, Joel S. Perlmutter, and Brad A. Racette

Hypercaloric Enteral Nutrition in Patients With Amyotrophic Lateral Sclerosis: A Randomised Double-Blind Placebo-Controlled Phase 2 Trial, Anne Marie Wills, Jane Hubbard, Eric A. Macklin, Jonathan Glass, Rup Tandan, Ericka P. Simpson, Benjamin Brooks, Deborah Gelinas, Hiroshi Mitsumoto, Tahseen Mozaffar, Gregory P. Hanes, Shafeeq S. Ladha, Terry Heiman-Patterson, Jonathan Katz, Jau Shin Lou, Katy Mahoney, Daniela Grasso, Robert Lawson, Hong Yu, and et al.

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Sparse and Distributed Coding of Episodic Memory in Neurons of the Human Hippocampus, John T. Wixted, Larry R. Squire, Yoonhee Jang, Megan H. Papesh, Stephen D. Goldinger, Joel R. Kuhn, Kris A. Smith, David M. Treiman, and Peter N. Steinmetz

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Evaluation of tentorial length and angle in sleep-wake disturbances after mild traumatic brain injury, Karl Yaeger, Lea Alhilali, and Saeed Fakhran

Pertussis Toxin Modulates Microglia and T Cell Profile to Protect Experimental Autoimmune Encephalomyelitis, Jun Xiang Yin, Zhiwei Tang, Yan Gan, Lejun Li, Fu-Dong Shi, Stephen Coons, and Jiong Shi

Association of Amyloid Burden Brain Atrophy and Memory Deficits in Aged Apolipoprotein Epsilon-4 Mice, Junxiang Yin, Gregory H. Turner, Stephen W. Coons, Marwan Maalouf, Eric M. Reiman, and Jiong Shi

Submissions from 2013

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Neurodegeneration: The first IBRO-Middle east neuroscience conference, Abdu Adem, Omar El Agnaf, and Marwan N. Sabbagh

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Evaluation of a limited three-slice head CT protocol for monitoring patients with ventriculoperitoneal shunts, Lea M. Alhilali, Andreea C. Dohatcu, and Saeed Fakhran

Evaluation of the intervertebral disk angle for the assessment of anterior cervical diskoligamentous injury., L M Alhilali and S Fakhran

Estrogen receptor mutation in a girl with primary amenorrhea., M Asadi, S Ghafouri-Fard, D Zare-Abdollahi, A Ebrahim-Habibi, and N Matin

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Phase III Randomized Trial Comparing the Efficacy of Cediranib as Monotherapy and in Combination With Lomustine Versus Lomustine Alone in Patients With Recurrent Glioblastoma, Tracy T. Batchelor, Paul Mulholland, Bart Neyns, L. Burt Nabors, Mario Campone, Antje Wick, Warren Mason, Tom Mikkelsen, Surasak Phuphanich, Lynn S. Ashby, John DeGroot, Rao Gattamaneni, Lawrence Cher, Mark Rosenthal, Franz Payer, Juliane M. Jürgensmeier, Rakesh K. Jain, A. Gregory Sorensen, John Xu, and et al.

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Submandibular gland biopsy for the diagnosis of parkinson disease, Thomas G. Beach, Charles H. Adler, Brittany N. Dugger, Geidy Serrano, Jose Hidalgo, Jonette Henry-Watson, Holly A. Shill, Lucia I. Sue, Marwan N. Sabbagh, and Haruhiko Akiyama

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Successes and failures for drugs in late-stage development for alzheimer's disease, Camryn Berk and Marwan N. Sabbagh

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Clinical reasoning: an 85-year-old man with paresthesias and an unsteady gait, Aaron L. Berkowitz, Ruchira M. Jha, Joshua P. Klein, and Anthony A. Amato

The Established Status Epilepticus Trial 2013, Thomas Bleck, Hannah Cock, James Chamberlain, James Cloyd, Jason Connor, Jordan Elm, Nathan Fountain, Elizabeth Jones, Daniel Lowenstein, Shlomo Shinnar, Robert Silbergleit, David M. Treiman, Eugen Trinka, and Jaideep Kapur

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Clinicopathologic correlations in 172 cases of rapid eye movement sleep behavior disorder with or without a coexisting neurologic disorder, B. F. Boeve, M. H. Silber, T. J. Ferman, S. C. Lin, E. E. Benarroch, A. M. Schmeichel, J. E. Ahlskog, R. J. Caselli, S. Jacobson, M. Sabbagh, C. Adler, B. Woodruff, T. G. Beach, A. Iranzo, E. Gelpi, J. Santamaria, E. Tolosa, C. Singer, D. C. Mash, C. Luca, I. Arnulf, C. Duyckaerts, C. H. Schenck, M. W. Mahowald, Y. Dauvilliers, N. R. Graff-Radford, Z. K. Wszolek, J. E. Parisi, B. Dugger, M. E. Murray, and D. W. Dickson

Risk factors for dementia with Lewy bodies A case-control study, Brendon P. Boot, Carolyn F. Orr, J. Eric Ahlskog, Tanis J. Ferman, Rosebud Roberts, Vernon S. Pankratz, Dennis W. Dickson, Joseph Parisi, Jeremiah A. Aakre, Yonas E. Geda, David S. Knopman, Ronald C. Petersen, and Bradley F. Boeve

Hypersexuality in Dementia: A Case Presentation With Discussion, Anna D. Burke, Roy Yaari, Pierre N. Tariot, Adam S. Fleisher, Geri R. Hall, and Helle Brand

The Threat of Behavioral Changes in Dementia, Anna D. Burke, Roy Yaari, Pierre N. Tariot, Geri R. Hall, Jan Dougherty, Helle Brand, and Adam S. Fleisher

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The clinical problem of neuropsychiatric signs and symptoms in dementia, Anna Burke, Geri Hall, and Pierre N. Tariot

Managing common complex symptomatic epilepsies: Tumors and trauma, Jorge G. Burneo, Joseph I. Sirven, Lily Wong Kiesel, Charles J. Vecht, Lara Jehi, Steve S. Chung, Joon Uhm, Jeffrey M. Politsky, Edward F. Chang, Aatif M. Husain, William O. Tatum, Kimford J. Meador, Katherine Noe, Dale C. Hesdorffer, Susan T. Herman, Samuel Wiebe, Jerome Engel, Sara Schrader, Karen L. Parko, March A. Dichter, Patrick Kwan, Eric Kossoff, and Michael R. Sperling

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Alzheimer disease periventricular white matter lesions exhibit specific proteomic profile alterations, Eduardo M. Castaño, Chera L. Maarouf, Terence Wu, Maria Celeste Leal, Charisse M. Whiteside, Lih Fen Lue, Tyler A. Kokjohn, Marwan N. Sabbagh, Thomas G. Beach, and Alex E. Roher

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High-Dose Donepezil (23 mg/day) for the Treatment of Moderate and Severe Alzheimer's Disease: Drug Profile and Clinical Guidelines, Jeffrey L. Cummings, David Geldmacher, Martin Farlow, Marwan Sabbagh, Daniel Christensen, and Peter Betz

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BACE1 levels by APOE genotype in non-demented and Alzheimer's post-mortem brains, Boris Decourt, Amanda Gonzales, Thomas G. Beach, Michael Malek-Ahmadi, Aaron Walker, Lucia Sue, Douglas G. Walker, and Marwan N. Sabbagh

Recent Perspectives on APP, Secretases, Endosomal Pathways and How they Influence Alzheimer's Related Pathological Changes in Down Syndrome, Boris Decourt, William Mobley, Eric Reiman, Raj Jatin Shah, and Marwan N. Sabbagh

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Can platelet BACE1 levels be used as a biomarker for Alzheimer's disease? Proof-of-concept study, Boris Decourt, Aaron Walker, Amanda Gonzales, Michael Malek-Ahmadi, Carolyn Liesback, Kathryn J. Davis, Christine M. Belden, Sandra A. Jacobson, and Marwan N. Sabbagh

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Differential processing of amyloid precursor protein in brain and in peripheral blood leukocytes, Elaine Delvaux, Karen Bentley, Victoria Stubbs, Marwan Sabbagh, and Paul D. Coleman

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Mu-opioid receptor A118G polymorphism in healthy volunteers affects hypothalamic-pituitary-adrenal axis adrenocorticotropic hormone stress response to metyrapone, Elizabeth Ducat, Brenda Ray, Gavin Bart, Yoshie Umemura, Jack Varon, Ann Ho, and Mary Jeanne Kreek

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Symptomatic white matter changes in mild traumatic brain injury resemble pathologic features of early Alzheimer dementia, Saeed Fakhran, Karl Yaeger, and Lea Alhilali

Yield of CT angiography and contrast-enhanced MR imaging in patients with dizziness., S Fakhran, L Alhilali, and B F Branstetter

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Effects of donepezil 23 mg on Severe Impairment Battery domains in patients with moderate to severe Alzheimer's disease: Evaluating the impact of baseline severity, Steven Ferris, Jeffrey Cummings, Daniel Christensen, Rachelle Doody, Martin Farlow, Marwan Sabbagh, Liang Liu, Joan MacKell, and Randi Fain

Neuro-otology. Preface., Terry D Fife

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Posttraumatic Vertigo and Dizziness, Terry D. Fife and Christopher Giza

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Apolipoprotein E ε4 and age effects on florbetapir positron emission tomography in healthy aging and Alzheimer disease, Adam S. Fleisher, Kewei Chen, Xiaofen Liu, Napatkamon Ayutyanont, Auttawut Roontiva, Pradeep Thiyyagura, Hillary Protas, Abhinay D. Joshi, Marwan Sabbagh, Carl H. Sadowsky, Reisa A. Sperling, Christopher M. Clark, Mark A. Mintun, Michael J. Pontecorvo, R. Edward Coleman, P. M. Doraiswamy, Keith A. Johnson, Alan P. Carpenter, Daniel M. Skovronsky, and Eric M. Reiman

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Antiepileptic drug treatment: new drugs and new strategies, Jacqueline A. French and Deana M. Gazzola

Caloric intake, aging, and mild cognitive impairment: A population-based study, Yonas E. Geda, Marion Ragossnig, Lewis A. Roberts, Rosebud O. Roberts, V. Shane Pankratz, Teresa J.H. Christianson, Michelle M. Mielke, James A. Levine, Bradley F. Boeve, Ondřej Sochor, Eric G. Tangalos, David S. Knopman, and Ronald C. Petersen

Neuropsychiatric symptoms in Alzheimer's disease: Past progress and anticipation of the future, Yonas E. Geda, Lon S. Schneider, Laura N. Gitlin, David S. Miller, Gwenn S. Smith, Joanne Bell, Jovier Evans, Michael Lee, Anton Porsteinsson, Krista L. Lanctôt, Paul B. Rosenberg, David L. Sultzer, Paul T. Francis, Henry Brodaty, Prasad P. Padala, Chiadikaobi U. Onyike, Luis Agüera Ortiz, Sonia Ancoli-Israel, Donald L. Bliwise, Jennifer L. Martin, Michael V. Vitiello, Kristine Yaffe, Phyllis C. Zee, Nathan Herrmann, Robert A. Sweet, Clive Ballard, Ni A. Khin, Cara Alfaro, Patrick S. Murray, Susan Schultz, and Constantine G. Lyketsos

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Neuro-ophthalmology around the world, Karl C. Golnik

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Reply: Intentional extreme anisometropic pseudophakic monovision, Karl C. Golnik

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Parkinson disease is not associated with C9ORF72 repeat expansions, Matthew B. Harms, Drexel Neumann, Bruno A. Benitez, Breanna Cooper, David Carrell, Brad A. Racette, Joel S. Perlmutter, Alison Goate, and Carlos Cruchaga

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SMG1 identified as a regulator of Parkinson's disease-associated alpha-synuclein through siRNA screening., Adrienne Henderson-Smith, Donald Chow, Bessie Meechoovet, Meraj Aziz, Sandra A. Jacobson, Holly A. Shill, Marwan N. Sabbagh, John N. Caviness, Charles H. Adler, Erika D. Driver-Dunckley, Thomas G. Beach, Hongwei Yin, and Travis Dunckley

American clinical neurophysiology society's standardized critical care EEG terminology: 2012 version, L. J. Hirsch, S. M. Laroche, N. Gaspard, E. Gerard, A. Svoronos, S. T. Herman, R. Mani, H. Arif, N. Jette, Y. Minazad, J. F. Kerrigan, P. Vespa, S. Hantus, J. Claassen, G. B. Young, E. So, P. W. Kaplan, M. R. Nuwer, N. B. Fountain, and F. W. Drislane

Genome-wide scan of healthy human connectome discovers SPON1 gene variant influencing dementia severity., Neda Jahanshad, Priya Rajagopalan, Xue Hua, Derrek P Hibar, Talia M Nir, Arthur W Toga, Clifford R Jack, Andrew J Saykin, Robert C Green, Michael W Weiner, Sarah E Medland, Grant W Montgomery, Narelle K Hansell, Katie L McMahon, Greig I de Zubicaray, Nicholas G Martin, Margaret J Wright, Paul M Thompson, and Marwan N. Sabbagh

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Evolution of hypoxic-ischemic injury, Ruchira M. Jha, Aaron L. Berkowitz, and Joshua P. Klein

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The isolation, differentiation, and survival in vivo of multipotent cells from the postnatal rat filum terminale, Ruchira M. Jha, Ryan Chrenek, Laura M. Magnotti, and David L. Cardozo

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The postnatal human filum terminale is a source of autologous multipotent neurospheres capable of generating motor neurons, Ruchira M. Jha, Xiaojin Liu, Ryan Chrenek, Joseph R. Madsen, and David L. Cardozo

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Florbetapir (F18-AV-45) PET to assess amyloid burden in Alzheimer's disease dementia, mild cognitive impairment, and normal aging, Keith A. Johnson, Reisa A. Sperling, Christopher M. Gidicsin, Jeremy S. Carmasin, Jacqueline E. Maye, Ralph E. Coleman, Eric M. Reiman, Marwan N. Sabbagh, Carl H. Sadowsky, Adam S. Fleisher, P. Murali Doraiswamy, Alan P. Carpenter, Christopher M. Clark, Abhinay D. Joshi, Ming Lu, Michel Grundman, Mark A. Mintun, Michel J. Pontecorvo, and Daniel M. Skovronsky

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Extrapyramidal signs by dementia severity in alzheimer disease and dementia with lewy bodies, Berneet Kaur, Danielle J. Harvey, Charles S. Decarli, Lin Zhang, Marwan N. Sabbagh, and John M. Olichney

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Residency education professionalism vignettes, Rabeea Khan, Andrew G. Lee, Karl C. Golnik, and Jaya Paranilam

Evaluation of a practical visual MRI rating scale of brain white matter hyperintensities for clinicians based on largest lesion size regardless of location., K S King, R M Peshock, M W Warren, L Alhilali, K Hulsey, R McColl, M F Weiner, C Ayers, and A Whittemore

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Neurochemical profile of dementia pugilistica, Tyler A. Kokjohn, Chera L. Maarouf, Ian D. Daugs, Jesse M. Hunter, Charisse M. Whiteside, Michael Malek-Ahmadi, Emma Rodriguez, Walter Kalback, Sandra A. Jacobson, Marwan N. Sabbagh, Thomas G. Beach, and Alex E. Roher

Postictal bradyarrhythmia following an isolated seizure in a patient with left hemisphere stroke, Vaishnav Krishnan, Erick Tarula, Matthew P. Anderson, Khalid A. Hanafy, and Susan T. Herman

Is There Room for Non-Dopaminergic Treatment in Parkinson Disease?, Abraham N. Lieberman and Narayanan Krishnamurthi

Anaplastic Astrocytoma Masquerading as Hemorrhagic Stroke, Lejun Li, Junxiang Yin, Yumei Li, Wei Tian, Benyu Qiao, Zhiwei Tang, and Jiong Shi

Spontaneous Thalamic Hemorrhage as the First Presentation of Anaplastic Astrocytoma: A Case Report, Lejun Li, Junxiang Yin, and Jiong Shi

Transcranial magnetic stimulation for refractory focal status epilepticus in the intensive care unit, Anli Liu, Trudy Pang, Susan Herman, Alvaro Pascual-Leone, and Alexander Rotenberg

Depressive symptoms in healthy apolipoprotein e e4 carriers and noncarriers: A longitudinal study, Dona E.C. Locke, Amylou C. Dueck, Cynthia M. Stonnington, David S. Knopman, Yonas E. Geda, and Richard J. Caselli

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Quantitative appraisal of ventricular cerebrospinal fluid biomarkers in neuropathologically diagnosed Parkinson's disease cases lacking Alzheimer's disease pathology, Chera L. Maarouf, Thomas G. Beach, Charles H. Adler, Michael Malek-Ahmadi, Tyler A. Kokjohn, Brittany N. Dugger, Douglas G. Walker, Holly A. Shill, Sandra A. Jacobson, Marwan N. Sabbagh, and Alex E. Roher

Molecular Differences and Similarities Between Alzheimer's Disease and the 5XFAD Transgenic Mouse Model of Amyloidosis, Chera L. Maarouf, Tyler A. Kokjohn, Charisse M. Whiteside, MiMi P. Macias, Walter M. Kalback, Marwan N. Sabbagh, Thomas G. Beach, Robert Vassar, and Alex E. Roher

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Increased Alzheimer's disease neuropathology is associated with type 2 diabetes and ApoE ε4 carrier status, Michael Malek-Ahmadi, Thomas Beach, Aleksandra Obradov, Lucia Sue, Christine Belden, Kathryn Davis, Douglas G. Walker, Lih Fen Lue, Abdu Adem, and Marwan N. Sabbagh

Prevalence of Hippocampal Sclerosis in a Clinicopathologically Characterized Cohort, Michael Malek-Ahmadi, Vickram Kahlon, Charles H. Adler, Aleksandra Obradov, Kabir Thind, Holly A. Shill, Lucia I. Sue, John N. Caviness, Sandra Jacobson, and Marwan N. Sabbagh

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KIF6 719Arg carrier status association with homocysteine and C-Reactive protein in amnestic mild cognitive impairment and alzheimer's disease patients, Michael Malek-Ahmadi, Amar Patel, and Marwan N. Sabbagh

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Age-associated changes in monocyte and innate immune activation markers occur more rapidly in HIV infected women, Genevieve E. Martin, Maelenn Gouillou, Anna C. Hearps, Thomas A. Angelovich, Allen C. Cheng, Fiona Lynch, Wan-Jung Cheng, Geza Paukovics, Clovis S. Palmer, Richard M. Novak, Anthony Jaworowski, Alan L. Landay, and Suzanne M. Crowe

Assessing the temporal relationship between cognition and gait: Slow gait predicts cognitive decline in the mayo clinic study of aging, Michelle M. Mielke, Rosebud O. Roberts, Rodolfo Savica, Ruth Cha, Dina I. Drubach, Teresa Christianson, Vernon S. Pankratz, Yonas E. Geda, Mary M. Machulda, Robert J. Ivnik, David S. Knopman, Bradley F. Boeve, Walter A. Rocca, and Ronald C. Petersen

Aquatic therapy and alzheimer's disease, Kent W. Myers, Dina Capek, Holly Shill, and Marwan Sabbagh

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A fixed-dose randomized controlled trial of olanzapine for psychosis in Parkinson disease, Michelle J. Nichols, Johanna M. Hartlein, Meredith Ga Eicken, Brad A. Racette, and Kevin J. Black

Characteristics of Falls in the Epilepsy Monitoring Unit: A Retrospective Study, Sandipan Pati, Vishakhadatta M. Kumaraswamy, A. Deep, S. S. Chung, M. Plueger, G. Kiyota, and David M. Treiman

Diagnosis and Management of Epilepsy Associated With Hypothalamic Hamartoma: An Evidence-Based Systematic Review, Sandipan Pati, Myriam Sollman, Terry D. Fife, and Yu Tze Ng

Mild cognitive impairment due to Alzheimer disease in the community, Ronald C. Petersen, Paul Aisen, Bradley F. Boeve, Yonas E. Geda, Robert J. Ivnik, David S. Knopman, Michelle Mielke, Vernon S. Pankratz, Rosebud Roberts, Walter A. Rocca, Stephen Weigand, Michael Weiner, Heather Wiste, and Clifford R. Jack

Cardiac disease associated with increased risk of nonamnestic cognitive impairment, Rosebud O. Roberts, Yonas E. Geda, David S. Knopman, Ruth H. Cha, V. Shane Pankratz, Bradley F. Boeve, Eric G. Tangalos, Robert J. Ivnik, Michelle M. Mielke, and Ronald C. Petersen

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Bapineuzumab Alters Aβ Composition: Implications for the Amyloid Cascade Hypothesis and Anti-Amyloid Immunotherapy, Alex E. Roher, David H. Cribbs, Ronald C. Kim, Chera L. Maarouf, Charisse M. Whiteside, Tyler A. Kokjohn, Ian D. Daugs, Elizabeth Head, Carolyn Liebsack, Geidy Serrano, Christine Belden, Marwan N. Sabbagh, and Thomas G. Beach

Subjects harboring presenilin familial Alzheimer’s disease mutations exhibit diverse white matter biochemistry alterations, Alex E. Roher, Chera L. Maarouf, Michael Malek-Ahmadi, Jeffrey Wilson, Tyler A. Kokjohn, Ian D. Daugs, Charisse M. Whiteside, Walter M. Kalback, Mi Mi P. Macias, Sandra A. Jacobson, Marwan N. Sabbagh, Bernardino Ghetti, and Thomas G. Beach

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Bright light exposure reduces TH-positive dopamine neurons: implications of light pollution in Parkinson's disease epidemiology, Stefania Romeo, Cristina Viaggi, Daniela Di Camillo, Allison W. Willis, Luca Lozzi, Cristina Rocchi, Marta Capannolo, Gabriella Aloisi, Francesca Vaglini, Rita Maccarone, Matteo Caleo, Cristina Missale, Brad A. Racette, Giovanni U. Corsini, and Roberto Maggio

The association of neuropsychiatric symptoms in MCI with incident dementia and alzheimer disease, Paul B. Rosenberg, Michelle M. Mielke, Brian S. Appleby, Esther S. Oh, Yonas E. Geda, and Constantine G. Lyketsos

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Evaluating the cognitive effects of donepezil 23 mg/d in moderate and severe Alzheimer's disease: Analysis of effects of baseline features on treatment response, Marwan Sabbagh, Jeffrey Cummings, Daniel Christensen, Rachelle Doody, Martin Farlow, Liang Liu, Joan Mackell, and Randi Fain

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KIF6 719Arg allele is associated with statin effects on cholesterol levels in amnestic mild cognitive impairment and Alzheimer's disease patients, Marwan Sabbagh, Michael Malek-Ahmadi, Ian Levenson, and D. Larry Sparks

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The influence of Apolipoprotein E genotype on regional pathology in Alzheimer's disease, Marwan N. Sabbagh, Michael Malek-Ahmadi, Brittany N. Dugger, Katarina Lee, Lucia I. Sue, Geidy Serrano, Douglas G. Walker, Kathryn Davis, Sandra A. Jacobson, and Thomas G. Beach

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Posterior Reversible Encephalopathy Syndrome, Courtney M. Schusse, Alicia L. Peterson, and Jason P. Caplan

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Causes of Imbalance and Abnormal Gait That May Be Misdiagnosed, Holly A. Shill and Terry D. Fife

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Autonomic complaints in patients with restless legs syndrome, Natalya Shneyder, Charles H. Adler, Joseph G. Hentz, Holly Shill, John N. Caviness, Marwan N. Sabbagh, Thomas G. Beach, and Erika Driver-Dunckley

Epilepsy, antiseizure therapy, and sleep cycle parameters, Vladimir Shvarts and Steve Chung

Perampanel: Newly Approved Novel Antiepileptic Medication for Partial-Onset Seizures, Vladimir Shvarts and Steve Chung

Chronic obstructive pulmonary disease and association with mild cognitive impairment: The Mayo Clinic Study of Aging, Balwinder Singh, Ajay K. Parsaik, Michelle M. Mielke, Rosebud O. Roberts, Paul D. Scanlon, Yonas E. Geda, V. Shane Pankratz, Teresa Christianson, Barbara P. Yawn, and Ronald C. Petersen

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Amyloid deposition detected with florbetapir F 18 (18F-AV-45) is related to lower episodic memory performance in clinically normal older individuals, Reisa A. Sperling, Keith A. Johnson, P. Murali Doraiswamy, Eric M. Reiman, Adam S. Fleisher, Marwan N. Sabbagh, Carl H. Sadowsky, Alan Carpenter, Mat D. Davis, Ming Lu, Matthew Flitter, Abhinay D. Joshi, Christopher M. Clark, Michael Grundman, Mark A. Mintun, Daniel M. Skovronsky, and Michael J. Pontecorvo

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Optic nerve sheath fenestration vs cerebrospinal diversion procedures: what is the preferred surgical procedure for the treatment of idiopathic intracranial hypertension failing maximum medical therapy?, Arielle Spitze, Amina Malik, Nagham Al-Zubidi, Karl Golnik, and Andrew G. Lee

Pertussis Toxin Attenuates Experimental Autoimmune Encephalomyelitis by Upregulating Neuronal Vascular Endothelial Growth Factor, Zhiwei Tang, Junxiang Yin, Pengcheng Han, Yan Gan, Stephen W. Coons, Chongqian Wang, Marwan Maalouf, and Jiong Shi

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Health care utilization and costs among patients with ad with and without dysphagia, Haijun Tian, Safiya Abouzaid, Marwan N. Sabbagh, Wei Chen, Susan Gabriel, Kristijan H. Kahler, and Edward Kim

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Mechanisms Models and Biomarkers in Amyotrophic Lateral Sclerosis, Martin R. Turner, Robert Bowser, Lucie Bruijn, Luc Dupuis, Albert Ludolph, Michael McGrath, Giovanni Manfredi, Nicholas Maragakis, Robert G. Miller, Seth L. Pullman, Seward B. Rutkove, Pamela J. Shaw, Jeremy M. Shefner, and Kenneth H. Fischbeck

A Statistical Method for Predicting Seizure Onset Zones From Human Single-Neuron Recordings, André B. Valdez, Erin N. Hickman, David M. Treiman, Kris A Smith, and Peter N. Steinmetz

Recognition of facial emotional expression in amnestic mild cognitive impairment, Alexandra Varjassyová, Daniel Hořínek, Ross Andel, Jana Amlerova, Jan Laczó, Kateřina Sheardová, Hana Magerová, Iva Holmerová, Martin Vyhnálek, Ondřej Bradáč, Yonas E. Geda, and Jakub Hort

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Changes in properties of serine 129 phosphorylated α-synuclein with progression of Lewy-type histopathology in human brains, Douglas G. Walker, Lih Fen Lue, Charles H. Adler, Holly A. Shill, John N. Caviness, Marwan N. Sabbagh, Haruhiko Akiyama, Geidy E. Serrano, Lucia I. Sue, and Thomas G. Beach

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Cognitive functioning before and after surgical resection for hypothalamic hamartoma and epilepsy, Jennifer V. Wethe, George P. Prigatano, Jennifer Gray, Kristina Chapple, Harold L. Rekate, and John F. Kerrigan