The Barrow Neurological Institute is proud of its reputation as a medical research facility and is home to some of the most sophisticated research programs outside of an academic setting in the Southwestern United States. Researchers in the Barrow Neurosurgery Research Center are devoted to learning more about the causes of and treatments for a wide range of disorders, such as stroke, aneurysms, spinal cord injury, and hydrocephalus. Our research has led to treatments that are being used around the world. Within the Department are neurosurgeons who subspecialize in cerebrovascular and skull base, functional and stereotactic, pediatric, spine, tumor, and endovascular neurosurgery.
Physicians, scientists, and expert clinical staff come together with a commitment to developing new techniques for the prevention, diagnosis, treatment, and rehabilitation of neurological illnesses and injuries. The leadership of internationally respected physicians keeps Barrow at the forefront of neuroscience. The compassionate expertise of its extensive staff of nurses, technologists, therapists and support personnel is evident in every aspect of care provided.
Our mission is to advance the knowledge and practice of medicine in neuroscience through basic and clinical research, education of medical professionals, and innovation in clinical techniques and technology.
Submissions from 2025
Hippocampal Atrophy on Magnetic Resonance Imaging as a Surrogate Marker for Clinical Benefit and Neurodegeneration in Early Symptomatic Alzheimer's Disease: Synthesis of Evidence from Observational and Interventional Trials, Susan Abushakra, P Murali Doraiswamy, John A. Hey, Duygu Tosun, Frederik Barkhof, Jerome Barakos, Jeffrey Petrella, J Patrick Kesslak, Aidan Power, Marwan Sabbagh, Anton Porsteinsson, Sharon Cohen, Serge Gauthier, Craig Ritchie, David Watson, Emer McSweeney, Merce Boada, Earvin Liang, Luc Bracoud, Rosalind McLaine, Susan Flint, Jean F. Schaefer, Jeremy Yu, Margaret Bray, Suzanne Hendrix, Sam Dickson, Abe Durrant, Adem Albayrak, and Martin Tolar
Clinical Efficacy, Safety and Imaging Effects of Oral Valiltramiprosate in APOEε4/ε4 Homozygotes with Early Alzheimer's Disease: Results of the Phase III, Randomized, Double-Blind, Placebo-Controlled, 78-Week APOLLOE4 Trial, Susan Abushakra, Aidan Power, David Watson, Anton Porsteinsson, Marwan Sabbagh, Emer MacSweeney, Sharon Cohen, Mercè Boada Rovira, P Murali Doraiswamy, Earvin Liang, Susan Flint, J Patrick Kesslak, Rosalind McLaine, Adem Albayrak, Jean Schaefer, Jeremy Yu, Luke Tolar, Sam Dickson, John A. Hey, and Martin Tolar
Perspective: Minimally clinically important "symptomatic" benefit associated with disease modification resulting from anti-amyloid immunotherapy, John Alam and Marwan N. Sabbagh
LiveDrive AI: A Pilot Study of a Machine Learning-Powered Diagnostic System for Real-Time, Non-Invasive Detection of Mild Cognitive Impairment, Firas Al-Hindawi, Peter Serhan, Yonas E. Geda, Francis Tsow, Teresa Wu, and Erica Forzani
Dispersion-based cognitive intra-individual variability in former American football players: Association with traumatic encephalopathy syndrome, repetitive head impacts, and biomarkers, Caroline Altaras, Monica T. Ly, Olivia Schultz, William B. Barr, Sarah J. Banks, Jennifer V. Wethe, Yorghos Tripodis, Charles H. Adler, Laura J. Balcer, Charles Bernick, Henrik Zetterberg, Kaj Blennow, Nicholas Ashton, Elaine Peskind, Robert C. Cantu, Michael J. Coleman, Alexander P. Lin, Inga K. Koerte, Sylvain Bouix, Daniel Daneshvar, David W. Dodick, Yonas E. Geda, Douglas L. Katz, Jason L. Weller, Jesse Mez, Joseph N. Palmisano, Brett Martin, Jeffrey L. Cummings, Eric M. Reiman, Martha E. Shenton, and Robert A. Stern
Cholesterol-modifying strategies for Alzheimer disease: promise or fallacy?, Katia Azarfar, Boris Decourt, Brandon Sanchez Camacho, John Joshua Lawrence, Tania R. Omondi, and Marwan N. Sabbagh
ALSUntangled #77: Psilocybin., Bhavya Bakshi, Sandeep Yerraguntla, Carmel Armon, Paul Barkhaus, Tulio Bertorini, Robert Bowser, Sarah Breevoort, Mark Bromberg, Andrew Brown, Gregory T Carter, Vincent Chang, Jesse Crayle, Timothy Fullam, Maxwell Greene, Terry Heiman-Patterson, Carlayne Jackson, Sartaj Jhooty, Elise Mallon, Javier Mascias Cadavid, Christopher J Mcdermott, Gary Pattee, Kaitlyn Pierce, Dylan Ratner, Yuyao Sun, Olivia Wang, Paul Wicks, Martina Wiedau, and Richard Bedlack
Physical activity and the outcome of cognitive trajectory: a machine learning approach, Bettina Barisch-Fritz, Jay Shah, Jelena Krafft, Yonas E. Geda, Teresa Wu, Alexander Woll, and Janina Krell-Roesch
Physical fitness and incident mild cognitive impairment: a systematic review, Matteo Bergmann, Yonas Endale Geda, Klaus Boes, Alexander Woll, and Janina Krell-Roesch
Brain photobiomodulation: a potential treatment in Alzheimer's and Parkinson's diseases, Guillaume Blivet, Benjamin Touchon, Hugo Cavadore, Sara Guillemin, Frédéric Pain, Michael Weiner, Marwan Sabbagh, Cécile Moro, and Jacques Touchon
Risk of Developing Alzheimer Disease in Relation to Common Infections, Alejandra Camacho-Soto, Irene Faust, Osvaldo J. Laurido-Soto, Jordan A. Killion, Natalie Senini, Brittany Krzyzanowski, and Brad A. Racette
Transthyretin abnormalities in amyotrophic lateral sclerosis: High molecular weight species in cerebrospinal fluid and stromal deposits in choroid plexus, Mahlon Collins, Heather Kwapiszeski, Jiyan An, Deyri Garcia, Danielle Peller, Shafeeq Ladha, Robert Bowser, and Nadine Bakkar
Utilizing T1-weighted MRI intensity indices to evaluate in-vivo neurotoxicity in a South African cohort with environmental manganese exposure, Susan R. Criswell, Irene Faust, Susan Searles Nielsen, Wendy W. Dlamini, Gill Nelson, Jay R. Turner, Joshua S. Shimony, Jason Lenox-Krug, Jordan A. Killion, T Noah Hutson, and Brad A. Racette
Large-scale proteomics project seeks cures for neurodegenerative diseases, Boris Decourt, Marwan N. Sabbagh, and Michelle M. Mielke
Mapping the Landscape of Diaschisis in Traumatic Brain Injury: A Scoping Review, Madison Evans, Cigdem Tosun, Ruchira M. Jha, Prajwal Ciryam, Volodymyr Gerzanich, and J Marc Simard
2024 Update of the RECOVER-Adult Long COVID Research Index., Linda N Geng, Kristine M Erlandson, Mady Hornig, Rebecca Letts, Caitlin Selvaggi, Hassan Ashktorab, Ornina Atieh, Logan Bartram, Hassan Brim, Shari B Brosnahan, Jeanette Brown, Mario Castro, Alexander Charney, Peter Chen, Steven G Deeks, Nathaniel Erdmann, Valerie J Flaherman, Maher A Ghamloush, Paul Goepfert, Jason D Goldman, Jenny E Han, Rachel Hess, Ellie Hirshberg, Susan E Hoover, Stuart D Katz, J Daniel Kelly, Jonathan D Klein, Jerry A Krishnan, Joyce Lee-Iannotti, Emily B Levitan, Vincent C Marconi, Torri D Metz, Matthew E Modes, Janko Ž Nikolich, Richard M Novak, Igho Ofotokun, Megumi J Okumura, Sairam Parthasarathy, Thomas F Patterson, Michael J Peluso, Athena Poppas, Orlando Quintero Cardona, Jake Scott, Judd Shellito, Zaki A Sherif, Nora G Singer, Barbara S Taylor, Tanayott Thaweethai, Monica Verduzco-Gutierrez, Juan Wisnivesky, Grace A McComsey, Leora I Horwitz, and Andrea S Foulkes
Efficacy and Safety of OnabotulinumtoxinA for the Treatment of Pediatric Upper and Lower Limb Spasticity: Results From 2 Open-Label, Long-term Extension Trials, Mark Gormley, Darcy Fehlings, Heakyung Kim, Marcin Bonikowski, Marta Banach, Fatma Gul, Jill Meilahn, Brad Racette, Nuoyu Huang, Xiaomeng Niu, Lynn M. James, and Rozalina Dimitrova
Cholinergic dysfunction in occupational manganese exposure, T Noah Hutson, Susan Searles Nielsen, Natalie Senini, John O'Donnell, Hubert P. Flores, Tamara Hershey, Joel S. Perlmutter, Anil Kumar Soda, Stephen M. Moerlein, Zhude Tu, Michael Kasper, Lianne Sheppard, Brad A. Racette, and Susan R. Criswell
Cerebrospinal Creatine Kinase BB Isoenzyme: A Biomarker for Predicting Outcome After Cardiac Arrest, Nicholas J. Johnson, Nassim Matin, Amita Singh, Arielle P. Davis, Hsuan-Chien Liao, James A. Town, David L. Tirschwell, Michael G. Nash, W T. Longstreth, and Sandeep P. Khot
Frailty in prodromal Parkinson's disease in Medicare beneficiaries, George K. Karway, Jordan A. Killion, Irene M. Faust, Kassu M. Beyene, Brad A. Racette, and Alejandra Camacho-Soto
Karway et al. respond to "Enhancing uptake of antidiabetic drugs to reduce cardiometabolic risk and dementia burden", George K. Karway, Jordan A. Killion, and Brad A. Racette
Regional variability of the impact of cardiometabolic diseases on incident dementia in United States Medicare beneficiaries, George K. Karway, Brittany Krzyzanowski, Jordan A. Killion, Irene M. Faust, Osvaldo J. Laurido-Soto, Marwan N. Sabbagh, and Brad A. Racette
Linking Symptom Inventories Using Semantic Textual Similarity, Eamonn Kennedy, Shashank Vadlamani, Hannah M. Lindsey, Kelly S. Peterson, Kristen Dams O'Connor, Ronak Agarwal, Houshang H. Amiri, Raeda K. Andersen, Talin Babikian, David A. Baron, Erin D. Bigler, Karen Caeyenberghs, Lisa Delano-Wood, Seth G. Disner, Ekaterina Dobryakova, Blessen C. Eapen, Rachel M. Edelstein, Carrie Esopenko, Helen M. Genova, Elbert Geuze, Naomi J. Goodrich-Hunsaker, Jordan Grafman, Asta K. Håberg, Cooper B. Hodges, Kristen R. Hoskinson, Elizabeth S. Hovenden, Andrei Irimia, Neda Jahanshad, Ruchira M. Jha, Finian Keleher, and Kimbra Kenney
Time saved in activities of daily living and whole-brain volume: Post hoc analysis of a randomized feasibility trial of gamma oscillation treatment in participants with mild or moderate Alzheimer's disease, Ralph Kern, Benjamin Haaland, Jessie Nicodemus-Johnson, Samuel Dickson, Matthew Morgan, Joshua R. Christensen, Marwan N. Sabbagh, Lily Lee, Mihaly Hajós, Julia Riddle, Chandran V. Seshagiri, Christian Howell, Craig Mallinckrodt, and Suzanne Hendrix
White matter hyperintensity severity modifies gut metabolite association with cognitive outcomes, Naruchorn Kijpaisalratana, Chia-Ling Phuah, Zsuzsanna Ament, Varun M. Bhave, Ana-Lucia Garcia-Guarniz, Jonathan Duskin, Catharine A. Couch, M Ryan Irvin, and W Taylor Kimberly
Efficacy and safety of avalglucosidase alfa in patients with late-onset Pompe disease after 145 weeks of treatment during the COMET trial, Priya S. Kishnani, Jordi Díaz-Manera, Sergey Illarioshkin, Ans T. van der Ploeg, Paula R. Clemens, John W. Day, Antonio Toscano, Hani Kushlaf, Shafeeq Ladha, Shahram Attarian, Gerson Carvalho, Anna Kostera-Pruszczyk, Sevim Erdem-Özdamar, Ozlem Goker-Alpan, Tahseen Mozaffar, Volker Straub, Mark Roberts, Kristina An Haack, Olivier Huynh-Ba, Swathi Tammireddy, Magali Periquet, Nathan Thibault, Tianyue Zhou, Mazen M. Dimachkie, and Benedikt Schoser
Physical and Cognitive Activities and Trajectories of AD Neuroimaging Biomarkers: Longitudinal Analysis in the Mayo Clinic Study of Aging, Janina Krell-Roesch, Jeremy A. Syrjanen, Allison L. Hansen, Prashanthi Vemuri, Eugene L. Scharf, Julie A. Fields, Walter K. Kremers, Val J. Lowe, Jonathan Graff-Radford, Clifford R. Jack, Ronald C. Petersen, Susan B. Racette, Alexander Woll, Maria Vassilaki, and Yonas E. Geda
Associations of Mid- and Late-Life Physical Activities With New-Onset Depression and Anxiety Among Older Adults, Janina Krell-Roesch, Jeremy A. Syrjanen, Walter K. Kremers, Bettina Barisch-Fritz, Jelena Krafft, DeJarra Johnson, Julie A. Fields, Ronald C. Petersen, Alexander Woll, Maria Vassilaki, and Yonas E. Geda
Multicenter Expanded Access Protocol for Research Through Access to Trehalose in People With Amyotrophic Lateral Sclerosis, Brooke Krivickas, Erica Scirocco, Elisa Giacomelli, Saloni Sharma, Molly Benson, Mackenzie Keegan, Jennifer Kulesa-Kelley, Lori B. Chibnik, Gabriella Casagrande, Lindsay Heyd, Marianne Chase, Kristin Drake, Silpa Mohapatra, Jennifer Linn Hagar, Meredith Gibbons Hasenoehrl, Derek Dagostino, Alexander V. Sherman, Alex Leite, Hong Yu, Jesse Rosenthal, Timothy Miller, Alexandra McCaffrey, Kelly Gwathmey, Eduardo Locatelli, Elham Bayat, Daragh Heitzman, Eufrosina Young, Namita A. Goyal, Jackie Whitesell, Kevin Felice, and Hristelina Ilieva
Ambient Trichloroethylene Exposure and Parkinson Disease Risk in Medicare Beneficiaries, Brittany Krzyzanowski, Kassu Mehari Beyene, Jay R. Turner, and Brad A. Racette
Cropland associated with risk of Parkinson's disease in the northern Great Plains, Brittany Krzyzanowski, Kassu M. Beyene, Susan Searles Nielsen, Jordan A. Killion, and Brad A. Racette
Developmental deletion of amyloid precursor protein precludes transcriptional and proteomic responses to brain injury, Valentina Lacovich, Maria Čarna, Sebastian J. Novotný, Shanshan Wang, Kateřina Texlová, Kristina Locker Kovačovicova, Neda Dragišić, Daniel Havas, Brian P. Head, Yonas E. Geda, Clara Limbäck-Stokin, and Gorazd Bernard Stokin
Validation of automated detection of REM sleep without atonia using in-laboratory and in-home recordings., Daniel J Levendowski, Lana M Chahine, Simon J G Lewis, Thomas J Finstuen, Andrea Galbiati, Chris Berka, Sherri Mosovsky, Hersh Parikh, Jack Anderson, Christine M Walsh, Joyce K Lee-Iannotti, Thomas C Neylan, Luigi Ferini Strambi, Bradley F Boeve, and Erik K St Louis
Serious Neurologic Adverse Events in Tofersen Clinical Trials for Amyotrophic Lateral Sclerosis, Alexandra Lovett, Sowmya Chary, Suma Babu, Gaëlle Bruneteau, Jonathan D. Glass, Merete Karlsborg, Shafeeq Ladha, Keith Mayl, Christopher McDermott, Robert C. Bucelli, Adriano Chiò, Toby A. Ferguson, Thos Cochrane, Stephanie Fradette, Karen Smirnakis, Jennifer Inra, Sohail Malek, and Laura Fanning
Blarcamesine for the treatment of Early Alzheimer's Disease: Results from the ANAVEX2-73-AD-004 Phase IIB/III trial, Stephen Macfarlane, Timo Grimmer, Ken Teo, Terence J. O'Brien, Michael Woodward, Jennifer Grunfeld, Alastair Mander, Amy Brodtmann, Bruce J. Brew, Philip Morris, Cathy Short, Susan Kurrle, Rosalyn Lai, Sneha Bharadwaj, Peter Drysdale, Jonathan Sturm, Simon J. Lewis, David Barton, Chris Kalafatis, Saif Sharif, Richard Perry, Nicholas Mannering, J Emer MacSweeney, Stephen Pearson, Craig Evans, Vivek Krishna, Alex Thompson, Malathy Munisamy, Neel Bhatt, Aliya Asher, and Sandra Connell
Development of Modified Japanese Versions of Questionnaires to Assess Physical and Cognitively Stimulating Activities, Shoya Matsumoto, Tomomi Satoh, Mitsuru Shinohara, Reo Kawano, Keisuke Suzuki, Janina Krell-Roesch, Michio Ide, Hirotaka Watada, Masahiro Akishita, Hidenori Arai, Izumi Kondo, Yonas E. Geda, and Naoyuki Sato
Visual-Guided Transillumination Method for Accurate Percutaneous Tracheal Tube Placement, Diane C. McLaughlin, Michael P. Schaller, Julian Bösel, and Mohamad Chmayssani
Visual-Guided Transillumination Method for Accurate Percutaneous Tracheal Tube Placement, Diane C. McLaughlin, Michael P. Schaller, Julian Bösel, and Mohamad Chmayssani
Polygenic Vulnerability to Intracranial Hypertension, Hemorrhage Progression, and Outcome in Traumatic Brain Injury, Margaux E. Miller, Benjamin E. Zusman, Chia-Ling Phuah, Erin McNally, David O. Okonkwo, Matthew Pease, Shashvat M. Desai, Anupama Rani, Nasathapot Namphol, Aditya Kumar, Raemier A. Javelosa, Adam T. Eberle, Semeon Afework, Joshua Catapano, Charles S. Cox, Patrick M. Kochanek, Yvette P. Conley, Ava M. Puccio, and Ruchira M. Jha
Exploring the neuroprotective potential of immunosuppressants in Parkinson's disease, Huiam M. Mubarak, Brad A. Racette, Jordan A. Killion, Irene M. Faust, Osvaldo J. Laurido-Soto, Sai Anmisha Doddamreddy, and Susan Searles Nielsen
Physical activity and gait in patients with idiopathic normal pressure hydrocephalus: a literature review, Kathrin Oebel, Tobias Moeller, Julie Etingold, Till Brombach, Sana Aslam, Justin L. Hoskin, Yonas E. Geda, Alexander Woll, and Janina Krell-Roesch
Efficacy and Safety of Zilucoplan in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial, Sabrina Paganoni, Christina N. Fournier, Eric A. Macklin, Lori B. Chibnik, Melanie Quintana, Benjamin R. Saville, Michelle A. Detry, Matteo Vestrucci, Joe Marion, Anna McGlothlin, Senda Ajroud-Driss, Marianne Chase, Lindsay Pothier, Brittney A. Harkey, Hong Yu, Alexander V. Sherman, Jeremy M. Shefner, Meghan Hall, Gale Kittle, James D. Berry, Suma Babu, Jinsy Andrews, Derek Dagostino, Eric Tustison, Elisa Giacomelli, Erica Scirocco, Gustavo Alameda, Eduardo Locatelli, Doreen Ho, Adam Quick, and Jonathan Katz
Sleep Promotion in the Hospitalized Elderly., Sairam Parthasarathy, Monisha Das Ireland, and Joyce Lee-Iannotti
A Longitudinal Investigation of Prediabetes, Diabetes, HbA1c and Cognitive Trajectories Among Cognitively Unimpaired Individuals, Anna Pink, Janina Krell-Roesch, Jeremy A. Syrjanen, Maria Vassilaki, Julie A. Fields, Bernhard Iglseder, Elmar Aigner, Walter K. Kremers, Clifford R. Jack, Susan B. Racette, Ronald C. Petersen, and Yonas E. Geda
The longitudinal association between dyslipidemia and cognitive trajectory, Anna Pink, Janina Krell-Roesch, Jeremy A. Syrjanen, Maria Vassilaki, Julie A. Fields, Bernhard Iglseder, Elmar Aigner, Walter K. Kremers, Clifford R. Jack, Susan B. Racette, Ronald C. Petersen, and Yonas E. Geda
Fosgonimeton in mild-to-moderate Alzheimer's disease, Anton P. Porsteinsson, Marwan Sabbagh, Pierre N. Tariot, Kevin J. Church, Javier San Martin, Kai-Bin C. Ooi, Simon Daggett, Michael D. Hale, Richard Holub, and Hans J. Moebius
Characterizing Neurobehavioral Dysregulation Among Former American Football Players: Findings From the DIAGNOSE CTE Research Project, Surya V. Pulukuri, Tessa R. Fagle, Diana Trujillo-Rodriguez, Suzan van Amerongen, Charles Bernick, Yonas E. Geda, Jennifer V. Wethe, Elaine R. Peskind, Douglas I. Katz, Michael L. Alosco, Joseph N. Palmisano, Yorghos Tripodis, Charles H. Adler, Laura J. Balcer, Eric M. Reiman, Martha E. Shenton, Jeffrey L. Cummings, and Robert A. Stern
Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer's disease, Farid Rajabli, Penelope Benchek, Giuseppe Tosto, Nicholas Kushch, Jin Sha, Katrina Bazemore, Congcong Zhu, Wan-Ping Lee, Jacob Haut, Kara L. Hamilton-Nelson, Nicholas R. Wheeler, Yi Zhao, John J. Farrell, Michelle A. Grunin, Yuk Yee Leung, Pavel P. Kuksa, Donghe Li, Eder Lucio da Fonseca, Jesse B. Mez, Ellen L. Palmer, Jagan Pillai, Richard M. Sherva, Yeunjoo E. Song, Xiaoling Zhang, Takeshi Ikeuchi, Taha Iqbal, Omkar Pathak, Otto Valladares, Dolly Reyes-Dumeyer, Amanda B. Kuzma, and Erin Abner
Electrophysiology in disorders of consciousness, Mohamed Ridha, Aditya Kumar, and Jan Claassen
Left Ventricular Hypertrophy and Ischemic Lesions After Intracerebral Hemorrhage, Mohamed Ridha, Marialaura Simonetto, Fernanda Carvalho Poyraz, Evan Hess, Aditya Kumar, Seyedmehdi Payabvash, Sachin Agarwal, Shivani Ghoshal, Jan Claassen, E Sander Connolly, Soojin Park, Marwah Abdalla, and David Roh
Safety considerations of semaglutide in the potential treatment of Alzheimer's disease: A pooled analysis of semaglutide in adults aged ≥ 65 years, Marwan Sabbagh, Cristina Boschini, Sharon Cohen, Magnus Fugger, Frank Jessen, Sune Dandanell, Sue D. Pedersen, Luis Rafael Tarazona, and Vanita R. Aroda
Repurposing glucagon-like peptide-1 receptor agonists for the treatment of neurodegenerative disorders, Marwan N. Sabbagh, Jeffrey L. Cummings, Clive Ballard, Wiesje M. van der Flier, Michael T. Heneka, Jens Juul Holst, Lotte Bjerre Knudsen, Stephen Salloway, Malú Gámez Tansey, and Daniel J. Drucker
Rebuttal letter on behalf of all authors in response to the Letter to the Editor, Marwan Noel Sabbagh
Alzheimer's disease: Clinical trials to watch, Marwan Noel Sabbagh, Jessica Kennedy, Jad Majeed, and Boris Decourt
Characterizing the Journey of Early Alzheimer's Disease in Patients Initiating Lecanemab Treatment in the United States: A Real-World Evidence Study, Marwan N. Sabbagh, Chenyue Zhao, Malena Mahendran, Se Ryeong Jang, François Laliberté, Hideki Toyosaki, Kaixin Zhang, Feride Frech, and Kavita V. Nair
Sex Differences in Long COVID., Dimpy P Shah, Tanayott Thaweethai, Elizabeth W Karlson, Hector Bonilla, Benjamin D Horne, Janet M Mullington, Juan P Wisnivesky, Mady Hornig, Daniel J Shinnick, Jonathan D Klein, Nathaniel B Erdmann, Shari B Brosnahan, Joyce K Lee-Iannotti, Torri D Metz, Christine Maughan, Ighovwerha Ofotokun, Harrison T Reeder, Lauren E Stiles, Aasma Shaukat, Rachel Hess, Hassan Ashktorab, Logan Bartram, Ingrid V Bassett, Jacqueline H Becker, Hassan Brim, Alexander W Charney, Tananshi Chopra, Rebecca G Clifton, Steven G Deeks, Kristine M Erlandson, Daniel S Fierer, Valerie J Flaherman, Vivian Fonseca, Jennifer C Gander, Sally L Hodder, Vanessa L Jacoby, Pavitra Kotini-Shah, Jerry A Krishnan, Andre Kumar, Bruce D Levy, David Lieberman, Jenny J Lin, Jeffrey N Martin, Grace A McComsey, Talal Moukabary, Megumi J Okumura, Michael J Peluso, Clifford J Rosen, George Saade, Pankil K Shah, Zaki A Sherif, Barbara S Taylor, Katherine R Tuttle, Alfredo E Urdaneta, Julie A Wallick, Zanthia Wiley, David Zhang, Leora I Horwitz, Andrea S Foulkes, and Nora G Singer
Predicting cognitive decline from neuropsychiatric symptoms and Alzheimer's disease biomarkers: A machine learning approach to a population-based data, Jay Shah, Janina Krell-Roesch, Erica Forzani, David S. Knopman, Cliff R. Jack, Ronald C. Petersen, Yiming Che, Teresa Wu, and Yonas E. Geda
A Mouse Model of Temporal Lobe Contusion, J Marc Simard, Cigdem Tosun, Orest Tsymbalyuk, Mitchell Moyer, Kaspar Keledjian, Natalya Tsymbalyuk, Adedayo Olaniran, Madison Evans, Jenna Langbein, Ziam Khan, Matthew Kreinbrink, Prajwal Ciryam, Jesse A. Stokum, Ruchira M. Jha, Alexander Ksendzovsky, and Volodymyr Gerzanich
MyEveryCise: A method for everyday exercise using 'an activity of daily living' as a cue, Hirobumi Tada, Mitsuru Shinohara, Asuka Teramoto, Shosuke Satake, Janina Krell-Roesch, Shoya Matsumoto, Minoru Yamada, Tomomi Satoh, Reo Kawano, Keisuke Suzuki, Izumi Kondo, Masahiro Akishita, Hidenori Arai, Yonas E. Geda, Hirotaka Watada, and Naoyuki Sato
Correction to: Gender-based violence in the context of armed conflict in the Amhara Region, Northern Ethiopia, Desalew Salew Tewabe, Muluken Azage, Gizachew Yismaw Wubetu, Sisay Awoke Fenta, Mulugeta Dile Worke, Amanu Mekonen Asres, Wallelign Alemnew Getnet, Genet Gedamu Kassie, Yonatan Menber, Alemtsehay Mekonnen Munea, Taye Zeru, Selamawit Alemayehu Bekele, Sadiya Osman Abdulahi, Tigist Biru Adamne, Hiwot Debebe Belete, Belay Bezabih Beyene, Melkamu Abte, Tesfaye B. Mersha, Abel Fekadu Dadi, Daniel A. Enquobahrie, Souci M. Frissa, and Yonas E. Geda
Predicting Post-Mortem α-Synuclein Pathology by the Combined Presence of Probable REM sleep behavior disorder and Hyposmia., Cécilia Tremblay, Charles H Adler, Holly A Shill, Erika Driver-Dunckley, Shyamal Mehta, Parichita Choudhury, Christine Belden, David R Shprecher, Joyce K Lee-Iannotti, Alireza Atri, Geidy E Serrano, and Thomas G Beach
Nonamyloid-beta active immunization for the treatment of Alzheimer's disease, Olivia Triplett, Nicole Varda, Boris Decourt, and Marwan N. Sabbagh
Active Immunization Targeting Amyloid β for the Treatment of Alzheimer's Disease, Olivia Triplett, Nicole Varda, Boris Decourt, Rodrigo Vasconcellos, and Marwan N. Sabbagh
Incidence and potential predictors of first pass effect within 30 min of groin puncture: An exploratory single-center study, Tshibambe Nathanael Tshimbombu, Shashvat Desai, Yaswanth Chintaluru, Paige Banyas, Angelina Cooper, Andrew Ducruet, Felipe C. Albuquerque, and Ashutosh Jadhav
Catecholamine Dysregulation in Former American Football Players: Findings From the DIAGNOSE CTE Research Project, Suzan van Amerongen, Elaine R. Peskind, Yorghos Tripodis, Charles H. Adler, Laura J. Balcer, Charles Bernick, Michael L. Alosco, Douglas Katz, Sarah J. Banks, William B. Barr, Robert C. Cantu, David W. Dodick, Yonas E. Geda, Jesse Mez, Jennifer V. Wethe, Jason L. Weller, Daniel H. Daneshvar, Joseph Palmisano, Tess Fagle, Minna Holleck, Bailey Kossow, Surya Pulukuri, Fatima Tuz-Zahra, Elizabeth Colasurdo, Carl Sikkema, Jeffrey Iliff, Ge Li, Martha E. Shenton, Eric M. Reiman, Jeffrey L. Cummings, and Robert A. Stern
Patterns of Factors in the National Institute on Aging Health Disparities Research Framework Domains and Mild Cognitive Impairment Risk, Maria Vassilaki, Jeremiah A. Aakre, Timothy G. Lesnick, Walter K. Kremers, Jonathan Graff-Radford, David S. Knopman, Thomas H. Mosley, B Gwen Windham, Michael E. Griswold, Yonas E. Geda, Val J. Lowe, Clifford R. Jack, Ronald C. Petersen, and Prashanthi Vemuri
Microbial production of short-chain fatty acids attenuates long-term neurologic impairment after traumatic brain injury, Zujian Xiong, Brittany P. Dodson, Matthew B. Rogers, Chaim T. Sneiderman, Keri Janesko-Feldman, Vincent Vagni, Mioara Manole, Xuejun Li, Dhivyaa Rajasundaram, Robert S. Clark, Itay Raphael, Michael J. Morowitz, Eliana Mariño, Patrick M. Kochanek, Ruchira M. Jha, Gary Kohanbash, and Dennis W. Simon
Real-world use of diagnostic tests for mild cognitive impairment, Alzheimer's disease, and other dementias in Medicare fee-for-service beneficiaries, Jessie T. Yan, Allison Dillon, Tong Meng, Viviktha Ramesh, Marwan Noel Sabbagh, Vishakha Sharma, and Sophie Roth
New Diagnosis of Adrenocortical Carcinoma with Stroke Workup, Ruoyan Zhu, Tshibambe Nathanael Tshimbombu, Monica C. Rodriguez, Mercedes Martinez Gil, Kevin C. Yuen, and Paige Banyas
Submissions from 2024
APOLLOE4 Phase 3 study of oral ALZ-801/valiltramiprosate in, Susan Abushakra, Anton P Porsteinsson, Marwan Sabbagh, David Watson, Aidan Power, Earvin Liang, Emer MacSweeney, Merce Boada, Susan Flint, Rosalind McLaine, J Patrick Kesslak, John A Hey, and Martin Tolar
APOLLOE4 Phase 3 study of oral ALZ-801/valiltramiprosate in APOE ε4/ε4 homozygotes with early Alzheimer's disease: Trial design and baseline characteristics, Susan Abushakra, Anton P. Porsteinsson, Marwan Sabbagh, David Watson, Aidan Power, Earvin Liang, Emer MacSweeney, Merce Boada, Susan Flint, Rosalind McLaine, J Patrick Kesslak, John A. Hey, and Martin Tolar
Conjugal Synucleinopathies: A Clinicopathologic Study, Charles H. Adler, Matthew Halverson, Nan Zhang, Holly A. Shill, Erika Driver-Dunckley, Shyamal H. Mehta, Alireza Atri, John N. Caviness, Geidy E. Serrano, David R. Shprecher, Christine M. Belden, Marwan N. Sabbagh, Kathy Long, and Thomas G. Beach
Navigating the Landscape of Plasma Biomarkers in Alzheimer's Disease: Focus on Past, Present, and Future Clinical Applications., Sarrah E Ankeny, Julia R Bacci, Boris Decourt, Marwan N. Sabbagh, and Michelle M Mielke
Stroke and Transient Ischemic Attack., Paige Banyas and Ashutosh Jadhav
Safety and efficacy of arimoclomol in patients with early amyotrophic lateral sclerosis (ORARIALS-01): a randomised, double-blind, placebo-controlled, multicentre, phase 3 trial., Michael Benatar, Thomas Hansen, Dror Rom, Marie A Geist, Thomas Blaettler, William Camu, Magdalena Kuzma-Kozakiewicz, Leonard H van den Berg, Raul Juntas Morales, Adriano Chio, Peter M Andersen, Pierre-Francois Pradat, Dale Lange, Philip Van Damme, Gabriele Mora, Mariusz Grudniak, Matthew Elliott, Susanne Petri, Nicholas Olney, Shafeeq Ladha, Namita A Goyal, Thomas Meyer, Michael G Hanna, Colin Quinn, Angela Genge, Lorne Zinman, Duaa Jabari, Christen Shoesmith, Albert C Ludolph, Christoph Neuwirth, Sharon Nations, Jeremy M Shefner, Martin R Turner, Joanne Wuu, Richard Bennett, Hoang Dang, and Claus Sundgreen
Improved Sleep Correlates with Improved Quality of Life and Motor Symptoms with Foslevodopa/Foscarbidopa., K Ray Chaudhuri, Maurizio F Facheris, Bruno Bergmans, Filip Bergquist, S R Criswell, Jia Jia, Pavnit Kukreja, Yohei Mukai, Amy M Spiegel, Resmi Gupta, Lars Bergmann, and Rajesh Pahwa
Resting-state EEG predicts cognitive decline in a neuropathologically diagnosed longitudinal community autopsied cohort., Alexander Choi, Nan Zhang, Charles H Adler, Thomas G Beach, Holly A Shill, Erika Driver-Dunckley, Shyamal Mehta, Christine Belden, Alireza Atri, Marwan N Sabbagh, and John N Caviness
Validation of the RBD Symptom Severity Scale in the North American Prodromal Synucleinopathy Consortium., Parichita Choudhury, Joyce K Lee-Iannotti, Andrea O Busicescu, Pooja Rangan, Maria Livia Fantini, Alon Y Avidan, Donald L Bliwise, S R Criswell, Emmanuel H During, Jonathan E Elliott, Julie A Fields, Jean-Francois Gagnon, Michael J Howell, Daniel E Huddleston, Jennifer McLeland, Emmanuel Mignot, Mitchell G Miglis, Miranda M Lim, Amélie Pelletier, Carlos H Schenck, David Shprecher, Erik K St Louis, Aleksandar Videnovic, Yo-El S Ju, Bradley F Boeve, and Ronald Postuma
Pharmacotherapies for the Treatment of Progressive Supranuclear Palsy: A Narrative Review, Elise E. Dunning, Boris Decourt, Nasser H. Zawia, Holly A. Shill, and Marwan N. Sabbagh
Comorbid neurotrauma increases neurodegenerative-relevant cognitive, motor, and autonomic dysfunction in patients with rapid eye movement sleep behavior disorder: a substudy of the North American Prodromal Synucleinopathy Consortium., Jonathan E Elliott, Brittany R Ligman, Mohini D Bryant-Ekstrand, Allison T Keil, Katherine Powers, Cosette Olivo, Lee E Neilson, Ronald B Postuma, Amélie Pelletier, Jean-François Gagnon, Ziv Gan-Or, Eric Yu, Lang Liu, Erik K St Louis, Leah K Forsberg, Julie A Fields, Owen A Ross, Daniel E Huddleston, Donald L Bliwise, Alon Y Avidan, Michael J Howell, Carlos H Schenck, Jennifer McLeland, S R Criswell, Aleksandar Videnovic, Emmanuel H During, Mitchell G Miglis, David R Shprecher, Joyce K Lee-Iannotti, Bradley F Boeve, Yo-El S Ju, and Miranda M Lim
Varoglutamstat: Inhibiting Glutaminyl Cyclase as a Novel Target of Therapy in Early Alzheimer's Disease., Howard H Feldman, Karen Messer, Yuqi Qiu, Marwan Sabbagh, Douglas Galasko, R Scott Turner, Oscar Lopez, Amanda Smith, January Durant, Jody-Lynn Lupo, Carolyn Revta, Archana Balasubramanian, Kerstin Kuehn-Wache, Tanja Wassmann, Sylvia Schell-Mader, Diane M Jacobs, David P Salmon, Gabriel Léger, Mari L DeMarco, and Frank Weber
Avatrombopag for the treatment of patients with chemotherapy-induced thrombocytopenia: A case series., Robert Galamaga, Stephanie Johnston, and Cassaundra Acosta
Paraneoplastic Calmodulin Kinase-Like Vesicle-Associated Protein (CAMKV) Autoimmune Encephalitis., Michael Gilligan, Connie E Lesnick, Yong Guo, Michael J Bradshaw, Shafeeq S Ladha, Mihaela Nowak, Maulik P Shah, John R Wittenborn, Eati Basal, Shannon Hinson, Binxia Yang, Divyanshu Dubey, John R Mills, Sean J Pittock, Anastasia Zekeridou, and Andrew McKeon
Olfactory tract/bulb metal concentration in Manganese-exposed mineworkers., Luis F Gonzalez-Cuyar, Gill Nelson, Susan Searles Nielsen, Wendy W Dlamini, Amelia Keyser-Gibson, C Dirk Keene, Michael Paulsen, S R Criswell, Natalie Senini, Lianne Sheppard, Shar Samy, Christopher D Simpson, Marissa G Baker, and Brad A Racette
Cerebral Edema Monitoring and Management Strategies: Results from an International Practice Survey., Tatiana Greige, Brian S Tao, Neha S Dangayach, Emily J Gilmore, Christa O'Hana Nobleza, H E Hinson, Sherry H Chou, Ruchira M. Jha, Sarah Wahlster, Meron A Gebrewold, Abhijit V Lele, and Charlene J Ong
A Modified Delphi Consensus Approach to Define Entrustable Professional Activities for Neurocritical Care Advanced Practice Providers, Daniel S. Harrison, Erika J. Sigman, Judy H. Ch'ang, Aarti Sarwal, Abigale Celotto, Alexandra Malone, Ariel Nowicki, Ashley Martin, Bryan Boling, Christa O'Hana Nobleza, Christopher Reeves, David M. Greer, Diane McLaughlin, Elizabeth O'B Woods, Emmaculate Fields, Erica Perets, Gemi E. Jannotta, Jennifer Mears, Kaitlyn Twomey, Kelly A. Rath, Kelly Peronti, Krista M. Garner, Matthew B. Bevers, Nicholas A. Morris, Paola Martinez, Sahar Zafar, Sarah Livesay, Sarah Wahlster, Thomas Lawson, and Catherine S. Albin
A Modified Delphi Consensus Approach to Define Entrustable Professional Activities for Neurocritical Care Advanced Practice Providers, Daniel S. Harrison, Erika J. Sigman, Judy H. Ch'ang, Aarti Sarwal, Abigale Celotto, Alexandra Malone, Ariel Nowicki, Ashley Martin, Bryan Boling, Christa O'Hana Nobleza, Christopher Reeves, David M. Greer, Diane McLaughlin, Elizabeth O'B Woods, Emmaculate Fields, Erica Perets, Gemi E. Jannotta, Jennifer Mears, Kaitlyn Twomey, Kelly A. Rath, Kelly Peronti, Krista M. Garner, Matthew B. Bevers, Nicholas A. Morris, Paola Martinez, Sahar Zafar, Sarah Livesay, Sarah Wahlster, Thomas Lawson, and Catherine S. Albin
Correction: Updated safety results from phase 3 lecanemab study in early Alzheimer's disease, Lawrence S. Honig, Marwan N. Sabbagh, Christopher H. van Dyck, Reisa A. Sperling, Steven Hersch, Andre Matta, Luigi Giorgi, Michelle Gee, Michio Kanekiyo, David Li, Derk Purcell, Shobha Dhadda, Michael Irizarry, and Lynn Kramer
Updated safety results from phase 3 lecanemab study in early Alzheimer's disease, Lawrence S. Honig, Marwan N. Sabbagh, Christopher H. van Dyck, Reisa A. Sperling, Steven Hersch, Andre Matta, Luigi Giorgi, Michelle Gee, Michio Kanekiyo, David Li, Derk Purcell, Shobha Dhadda, Michael Irizarry, and Lynn Kramer
Diversity, equity, and inclusion (DEI) in medical education: DEI at the bedside., Tennyson S Jellins, Tyler L Borko, RayLee Otero-Bell, Kelly Arnett, Scott Saunders, Sharon N Poisson, Karen D Orjuela, Setareh Salehi Omran, William J Jones, Michelle Leppert, Ashley Madera, Aaron Carlson, Daniel M Pastula, Brian M Sauer, Amanda L Piquet, and Nicole R Gonzales
Can Long-Term Outcomes of Posttraumatic Headache be Predicted?, Olivia Kingsford, Mustafa Yehya, Glynnis Zieman, and Kerry L Knievel
Concordance and test-retest consistency of sleep biomarker-based neurodegenerative disorder profiling., Daniel J Levendowski, Debby Tsuang, Lana M Chahine, Christine M Walsh, Chris Berka, Joyce K Lee-Iannotti, David Salat, Corrine Fischer, Gandis Mazeika, Bradley F Boeve, Luigi Ferini Strambi, Simon J G Lewis, Thomas C Neylan, and Erik K St Louis
Outcomes associated to the time to treatment with intravenous tenecteplase for acute ischaemic stroke: subgroup analysis of the TRACE-2 randomised controlled clinical trial, Shuya Li, Runqi Wangqin, Yuesong Pan, Aoming Jin, Hao Li, Lee H. Schwamm, Marc Fisher, Bruce C. Campbell, Mark W. Parsons, Ziran Wang, Hongguo Dai, Deyang Li, Runhui Li, Junhai Wang, David Wang, Yilong Wang, Xingquan Zhao, Zixiao Li, Huaguang Zheng, Yunyun Xiong, Xia Meng, and Yongjun Wang
Biomarker Assessment in Parkinson's Disease Dementia and Dementia with Lewy Bodies by the Immunomagnetic Reduction Assay and Clinical Measures., Giovanni R Malaty, Boris Decourt, Holly A Shill, and Marwan N Sabbagh
Considerations for widespread implementation of blood-based biomarkers of Alzheimer's disease., Michelle M Mielke, Matthew Anderson, J Wesson Ashford, Andreas Jeromin, Pei-Jung Lin, Allyson Rosen, Jamie Tyrone, Lawren VandeVrede, Deanna Willis, Oskar Hansson, Ara S Khachaturian, Suzanne E Schindler, Joan Weiss, Richard Batrla, Sasha Bozeat, John R Dwyer, Drew Holzapfel, Daryl Rhys Jones, James F Murray, Katherine A Partrick, Emily Scholler, George Vradenburg, Dylan Young, Joel B Braunstein, Samantha C Burnham, Fabricio Ferreira de Oliveira, Yan Helen Hu, Soeren Mattke, Zul Merali, Mark Monane, Marwan Noel Sabbagh, Eli Shobin, Michael W Weiner, and Chinedu T Udeh-Momoh
Recommendations for clinical implementation of blood-based biomarkers for Alzheimer's disease., Michelle M Mielke, Matthew Anderson, J Wesson Ashford, Andreas Jeromin, Pei-Jung Lin, Allyson Rosen, Jamie Tyrone, Lawren Vandevrede, Deanna R Willis, Oskar Hansson, Ara S Khachaturian, Suzanne E Schindler, Joan Weiss, Richard Batrla, Sasha Bozeat, John R Dwyer, Drew Holzapfel, Daryl Rhys Jones, James F Murray, Katherine A Partrick, Emily Scholler, George Vradenburg, Dylan Young, Joel B Braunstein, Samantha C Burnham, Fabricio Ferreira de Oliveira, Yan Helen Hu, Soeren Mattke, Zul Merali, Mark Monane, Marwan Noel Sabbagh, Eli Shobin, Michael Weiner, and Chinedu T Udeh-Momoh
Multicenter expanded access program for access to investigational products for amyotrophic lateral sclerosis., Dylan V Neel, Clara Baselga-Garriga, Molly Benson, Mackenzie Keegan, Marianne Chase, Derek D'Agostino, Kristin Drake, Jennifer Linn Hagar, Meredith Gibbons Hasenoehrl, Jennifer Kulesa-Kelley, Alex Leite, Silpa Mohapatra, Susanna Marie Portaro, Lindsay M Pothier, Jesse Rosenthal, Alexander V Sherman, Hong Yu, Alexandra McCaffrey, Doreen Ho, Sarah Luppino, Richard Bedlack, Daragh Heitzman, Senda Ajroud-Driss, Jonathan Katz, Kevin Felice, Charles Whitaker, Shafeeq Ladha, Gustavo Alameda, Eduardo Locatelli, Irfan A Qureshi, Michael T Hotchkin, Michael R Hayden, Merit E Cudkowicz, Suma Babu, James D Berry, and Sabrina Paganoni
Amyloid-Directed Antibodies: Past, Present, and Future., Keith Noorda, Kevin Noorda, Marwan N Sabbagh, John Bertelson, Jonathan Singer, and Boris Decourt
A Protocol for the Inclusion of Minoritized Persons in Alzheimer Disease Research From the ADNI3 Diversity Taskforce, Ozioma C. Okonkwo, Monica Rivera Mindt, Miriam T. Ashford, Catherine Conti, Joe Strong, Rema Raman, Michael C. Donohue, Rachel L. Nosheny, Derek Flenniken, Melanie J. Miller, Adam Diaz, Annabelle M. Soto, Beau M. Ances, Maryam R. Beigi, P Murali Doraiswamy, Ranjan Duara, Martin R. Farlow, Hillel T. Grossman, Jacobo E. Mintzer, Christopher Reist, Emily J. Rogalski, Marwan N. Sabbagh, Stephen Salloway, Lon S. Schneider, Raj C. Shah, Ronald C. Petersen, Paul S. Aisen, and Michael W. Weiner
The Influence of CYP2B6 Variants and Administration of Propofol on Patient Outcomes after Traumatic Brain Injury., Katherine O'Meara, Ava M Puccio, Dianxu Ren, Sandra Deslouches, Ruchira M. Jha, David O Okonkwo, and Yvette P Conley