The Barrow Neurological Institute is proud of its reputation as a medical research facility and is home to some of the most sophisticated research programs outside of an academic setting in the Southwestern United States. Researchers in the Barrow Neurosurgery Research Center are devoted to learning more about the causes of and treatments for a wide range of disorders, such as stroke, aneurysms, spinal cord injury, and hydrocephalus. Our research has led to treatments that are being used around the world. Within the Department are neurosurgeons who subspecialize in cerebrovascular and skull base, functional and stereotactic, pediatric, spine, tumor, and endovascular neurosurgery.
Physicians, scientists, and expert clinical staff come together with a commitment to developing new techniques for the prevention, diagnosis, treatment, and rehabilitation of neurological illnesses and injuries. The leadership of internationally respected physicians keeps Barrow at the forefront of neuroscience. The compassionate expertise of its extensive staff of nurses, technologists, therapists and support personnel is evident in every aspect of care provided.
Our mission is to advance the knowledge and practice of medicine in neuroscience through basic and clinical research, education of medical professionals, and innovation in clinical techniques and technology.
Submissions from 2020
Trial of sodium phenylbutyrate-taurursodiol for amyotrophic lateral sclerosis, Sabrina Paganoni, Eric A. Macklin, Suzanne Hendrix, James D. Berry, Michael A. Elliott, Samuel Maiser, Chafic Karam, James B. Caress, Margaret A. Owegi, Adam Quick, James Wymer, Stephen A. Goutman, Daragh Heitzman, Terry Heiman-Patterson, Carlayne E. Jackson, Colin Quinn, Jeffrey D. Rothstein, Edward J. Kasarskis, Jonathan Katz, Liberty Jenkins, Shafeeq Ladha, Timothy M. Miller, Stephen N. Scelsa, Tuan H. Vu, Christina N. Fournier, Jonathan D. Glass, Kristin M. Johnson, Andrea Swenson, Namita A. Goyal, Gary L. Pattee, and Patricia L. Andres
Newer Immunotherapies for the Treatment of Acute Neuromuscular Disease in the Critical Care Unit, Alok Patel, Fiona Lynch, and Starane A. Shepherd
Associations between high triglycerides and arterial stiffness in a population-based sample: Kardiovize Brno 2030 study, Iuliia Pavlovska, Sarka Kunzova, Juraj Jakubik, Jana Hruskova, Maria Skladana, Irma Magaly Rivas-Serna, Jose R. Medina-Inojosa, Francisco Lopez-Jimenez, Robert Vysoky, Yonas E. Geda, Gorazd B. Stokin, and Juan P. González-Rivas
Continuous EEG findings in patients with COVID-19 infection admitted to a New York academic hospital system, Jacob Pellinen, Elizabeth Carroll, Daniel Friedman, Michael Boffa, Patricia Dugan, David E. Friedman, Deana Gazzola, Amy Jongeling, Alcibiades J. Rodriguez, and Manisha Holmes
Degenerative dementia with proximal radial and lower vertical spatial neglect, Kulrithra Pisanuwongrak, Parunyou Julayanont, and Kenneth M. Heilman
ACI-24 vaccine in adults with Down syndrome, Michael S. Rafli, William C. Mobley, Brian G. Skotko, Marwan N. Sabbagh, Anna D. Burke, Shauna Yuan, Robert A. Rissman, Ronelyn Chavez, Saskia Delpretti, Oliver Sol, Greg Beth, Julian JG Gray, Antonio Melo dos Santos, Valerie Hliva, Marija Vukicevic, Marie Kosco-Vilbois, Andrea Pfeifer, and Howard H. Feldman
Alzheimer’s Disease Drug Development Pipeline 2020, Marwan N. Sabbagh
Rationale for Early Diagnosis of Mild Cognitive Impairment (MCI) supported by Emerging Digital Technologies, Marwan N. Sabbagh, M. Boada, S. Borson, M. Chilukuri, P. M. Doraiswamy, B. Dubois, J. Ingram, A. Iwata, A. P. Porsteinsson, K. L. Possin, G. D. Rabinovici, B. Vellas, S. Chao, A. Vergallo, and H. Hampel
Early Detection of Mild Cognitive Impairment (MCI) in Primary Care, Marwan N. Sabbagh, M. Boada, S. Borson, M. Chilukuri, B. Dubois, J. Ingram, A. Iwata, A. P. Porsteinsson, K. L. Possin, G. D. Rabinovici, B. Vellas, S. Chao, A. Vergallo, and H. Hampel
Early Detection of Mild Cognitive Impairment (MCI) in an At-Home Setting, Marwan N. Sabbagh, M. Boada, S. Borson, P. M. Doraiswamy, B. Dubois, J. Ingram, A. Iwata, A. P. Porsteinsson, K. L. Possin, G. D. Rabinovici, B. Vellas, S. Chao, A. Vergallo, and H. Hampel
Effects of a combined transcranial magnetic stimulation (TMS) and cognitive training intervention in patients with Alzheimer's disease, Marwan Sabbagh, Carl Sadowsky, Babak Tousi, Marc E. Agronin, Gustavo Alva, Carmel Armon, Charles Bernick, Andrew P. Keegan, Stella Karantzoulis, Eyal Baror, Moran Ploznik, and Alvaro Pascual-Leone
Editorial: Alzheimer's Disease Drug Development Pipeline 2020, M N. Sabbagh
Brain Volume: An Important Determinant of Functional Outcome After Acute Ischemic Stroke, Markus D. Schirmer, Kathleen L. Donahue, Marco J. Nardin, Adrian V. Dalca, Anne-Katrin Giese, Mark R. Etherton, Steven J. Mocking, Elissa C. McIntosh, John W. Cole, Lukas Holmegaard, Katarina Jood, Jordi Jimenez-Conde, Steven J. Kittner, Robin Lemmens, James F. Meschia, Jonathan Rosand, Jaume Roquer, Tatjana Rundek, Ralph L. Sacco, Reinhold Schmidt, Pankaj Sharma, Agnieszka Slowik, Tara M. Stanne, Achala Vagal, Johan Wasselius, Daniel Woo, Stephen Bevan, Laura Heitsch, Chia-Ling Phuah, Daniel Strbian, and Turgut Tatlisumak
A Phase 2, Double-Blind, Randomized, Dose-Ranging Trial Of Reldesemtiv In Patients With ALS, Jeremy M. Shefner, Jinsy A. Andrews, Angela Genge, Carlayne Jackson, Noah Lechtzin, Timothy M. Miller, Bettina M. Cockroft, Lisa Meng, Jenny Wei, Andrew A. Wolff, Fady I. Malik, Cynthia Bodkin, Benjamin R. Brooks, James Caress, Annie Dionne, Dominic Fee, Stephen A. Goutman, Namita A. Goyal, Orla Hardiman, Ghazala Hayat, Terry Heiman-Patterson, Daragh Heitzman, Robert D. Henderson, Wendy Johnston, Chafic Karam, Matthew C. Kiernan, Stephen J. Kolb, Lawrence Korngut, Shafeeq Ladha, Genevieve Matte, and Jesus S. Mora
Challenges and Opportunities with Causal Discovery Algorithms: Application to Alzheimer’s Pathophysiology, Xinpeng Shen, Sisi Ma, Prashanthi Vemuri, Gyorgy Simon, Michael W. Weiner, Paul Aisen, Ronald Petersen, Clifford R. Jack, Andrew J. Saykin, William Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, John Morris, Leslie M. Shaw, Zaven Khachaturian, Greg Sorensen, Maria Carrillo, Lew Kuller, Marc Raichle, Steven Paul, Peter Davies, Howard Fillit, Franz Hefti, David Holtzman, M. Marcel Mesulam, William Potter, and Peter Snyder
Alzheimer's disease beyond amyloid: Strategies for future therapeutic interventions, Jiong Shi, Marwan N. Sabbagh, and Bruno Vellas
Auditory Mapping With MEG: An Update on the Current State of Clinical Research and Practice With Considerations for Clinical Practice Guidelines, Vladimir Shvarts and Jyrki P. Mäkelä
Well Water and Parkinson's Disease in Medicare Beneficiaries: A Nationwide Case-Control Study, Maya R. Silver, Brad A. Racette, Umber Dube, Irene M. Faust, and Susan Searles Nielsen
Accuracy of ICD-10-CM claims-based definitions for epilepsy and seizure type, Jason R. Smith, Felipe J.S. Jones, Brandy E. Fureman, Jeffrey R. Buchhalter, Susan T. Herman, Neishay Ayub, Christopher McGraw, Sydney S. Cash, Daniel B. Hoch, and Lidia M.V.R. Moura
A telescope GWAS analysis strategy, based on SNPs-genes-pathways ensamble and on multivariate algorithms, to characterize late onset Alzheimer’s disease, Margherita Squillario, Giulia Abate, Federico Tomasi, Veronica Tozzo, Annalisa Barla, Daniela Uberti, Michael W. Weiner, Paul Aisen, Ronald Petersen, Jack R. Clifford, William Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, Andrew J. Saykin, John Morris, Leslie M. Shaw, Zaven Khachaturian, Greg Sorensen, Maria Carrillo, Lew Kuller, Marc Raichle, Steven Paul, Peter Davies, Howard Fillit, Franz Hefti, Davie Holtzman, and M. Marcel Mesulam
Coining the Pablo Picasso Syndrome, Ritika Suri and Ashhar Ali
Rapidly progressive dementia-associated N-type voltage-gated calcium channel antibody encephalopathy, Smathorn Thakolwiboon, Amputch Karukote, Gyeongmo Sohn, Walter R. Duarte-Celada, and Parunyou Julayanont
Olfactory gyrus intracerebral hemorrhage in a patient with COVID-19 infection, Sai Si Thu, Nassim Matin, and Steven R. Levine
Aducanumab, gantenerumab, BAN2401, and ALZ-801 - The first wave of amyloid-targeting drugs for Alzheimer's disease with potential for near term approval, Martin Tolar, Susan Abushakra, John A. Hey, Anton Porsteinsson, and Marwan Sabbagh
The path forward in Alzheimer's disease therapeutics: Reevaluating the amyloid cascade hypothesis, Martin Tolar, Susan Abushakra, and Marwan Sabbagh
Large Infarct Volume Post Thrombectomy: Characteristics, Outcomes, and Predictors, Daniel A. Tonetti, Shashvat M. Desai, Joseph Hudson, Bradley A. Gross, Ruchira M. Jha, Bradley J. Molyneaux, Brian T. Jankowitz, Tudor G. Jovin, and Ashutosh P. Jadhav
Benefit and risk of early intravenous heparin after thrombolysis in patients with acute ischemic stroke., Xu Tong, Yibin Cao, Wenzhi Wang, David Z. Wang, Yongjun Wang, and Yilong Wang
Relationship of amyloid beta and neurofibrillary tau deposition in Neurodegeneration in Aging Down Syndrome (NiAD) study at baseline, D. L. Tudorascu, C. M. Laymon, M. Zammit, D. S. Minhas, S. J. Anderson, P. A. Ellison, S. Zaman, B. M. Ances, M. Sabbagh, S. C. Johnson, C. A. Mathis, W. E. Klunk, B. L. Handen, B. T. Christian, and A. D. Cohen
DCE-MRI perfusion predicts pseudoprogression in metastatic melanoma treated with immunotherapy, Yoshie Umemura, Diane Wang, Kyung K. Peck, Jessica Flynn, Zhigang Zhang, Robin Fatovic, Erik S. Anderson, Kathryn Beal, Alexander N. Shoushtari, Thomas Kaley, and Robert J. Young
Brain amyloid, cortical thickness, and changes in activities of daily living, Maria Vassilaki, Jeremiah A. Aakre, Walter K. Kremers, Timothy G. Lesnick, Michelle M. Mielke, Yonas E. Geda, Mary M. Machulda, David S. Knopman, Lesley Butler, Martin Traber, Prashanthi Vemuri, Val J. Lowe, Clifford R. Jack, Rosebud O. Roberts, and Ronald C. Petersen
Medical Doctors and Dementia: A Longitudinal Study, Maria Vassilaki, Jeremy A. Syrjanen, Walter K. Kremers, Philip T. Hagen, David S. Knopman, Michelle M. Mielke, Yonas E. Geda, Rabe E. Alhurani, Mary M. Machulda, Rosebud O. Roberts, and Ronald C. Petersen
Original research: Second IVIg course in Guillain-Barré syndrome with poor prognosis: the non-randomised ISID study., Christine Verboon, Bianca van den Berg, David R Cornblath, Esmee Venema, Kenneth C Gorson, Michael P Lunn, Hester Lingsma, Peter Van den Bergh, Thomas Harbo, Kathleen Bateman, Yann Pereon, Søren H Sindrup, Susumu Kusunoki, James Miller, Zhahirul Islam, Hans-Peter Hartung, Govindsinh Chavada, Bart C Jacobs, Richard A C Hughes, Pieter A van Doorn, and Shafeeq S. Ladha
Subthalamic nucleus deep brain stimulation with a multiple independent constant current-controlled device in Parkinson's disease (INTREPID): a multicentre, double-blind, randomised, sham-controlled study., Jerrold L Vitek, Roshini Jain, Lilly Chen, Alexander I Tröster, Lauren E Schrock, Paul A House, Monique L Giroux, Adam O Hebb, Sierra M Farris, Donald M Whiting, Timothy A Leichliter, Jill L Ostrem, Marta San Luciano, Nicholas Galifianakis, Leo Verhagen Metman, Sepehr Sani, Jessica A Karl, Mustafa S Siddiqui, Stephen B Tatter, Ihtsham Ul Haq, Andre G Machado, Michal Gostkowski, Michele Tagliati, Adam N Mamelak, Michael S Okun, Kelly D Foote, Guillermo Moguel-Cobos, Francisco A Ponce, Rajesh Pahwa, Jules M Nazzaro, Cathrin M Buetefisch, Robert E Gross, Corneliu C Luca, Jonathan R Jagid, Gonzalo J Revuelta, Istvan Takacs, Michael H Pourfar, Alon Y Mogilner, Andrew P Duker, George T Mandybur, Joshua M Rosenow, Scott E Cooper, Michael C Park, Suketu M Khandhar, Mark Sedrak, Fenna T Phibbs, Julie G Pilitsis, Ryan J Uitti, and Philip A Starr
Decoding the brain through research-the future of brain health, David Z. Wang, Lee H. Schwamm, Tianyi Qian, and Qionghai Dai
Impact of COVID-2019 on stroke services in China: survey from the Chinese Stroke Association, Xia Wang, Menglu Ouyang, Cheryl Carcel, Chen Chen, Lingli Sun, Jie Yang, Yao Zhang, Guofang Chen, Shoujiang You, Yongjun Cao, Lu Ma, Xin Hu, Yi Sui, Craig Anderson, Lili Song, Yongjun Wang, and David Wang
Providing uninterrupted care during COVID-19 pandemic: experience from Beijing Tiantan Hospital, Xiaoyan Wang, Yu Chen, Zixiao Li, David Wang, and Yongjun Wang
China Stroke Statistics 2019: A Report From the National Center for Healthcare Quality Management in Neurological Diseases, China National Clinical Research Center for Neurological Diseases, the Chinese Stroke Association, National Center for Chronic and Non-communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention and Institute for Global Neuroscience and Stroke Collaborations, Yong-Jun Wang, Zi-Xiao Li, Hong-Qiu Gu, Yi Zhai, Yong Jiang, Xing-Quan Zhao, Yi-Long Wang, Xin Yang, Chun-Juan Wang, Xia Meng, Hao Li, Li-Ping Liu, Jing Jing, Jing Wu, An-Ding Xu, Qiang Dong, David Wang, and Ji-Zong Zhao
The association of white matter hyperintensities with stroke outcomes and antiplatelet therapy in minor stroke patients, Yu-Yuan Xu, Li-Xia Zong, Chang-Qing Zhang, Yue-Song Pan, Jing Jing, Xia Meng, Hao Li, Xing-Quan Zhao, Li-Ping Liu, David Wang, Yi-Long Wang, and Yong-Jun Wang
FAM222A encodes a protein which accumulates in plaques in Alzheimer’s disease, Tingxiang Yan, Jingjing Liang, Ju Gao, Luwen Wang, Hisashi Fujioka, Michael W. Weiner, Norbert Schuff, Howard J. Rosen, Bruce L. Miller, David Perry, Paul Aisen, Paul Aisen, Arthur W. Toga, Gustavo Jimenez, Michael Donohue, Devon Gessert, Kelly Harless, Jennifer Salazar, Yuliana Cabrera, Sarah Walter, Lindsey Hergesheimer, Arthur W. Toga, Karen Crawford, Scott Neu, Lon S. Schneider, Sonia Pawluczyk, Mauricio Becerra, Liberty Teodoro, and Bryan M. Spann
Effect of ApoE isoforms on mitochondria in Alzheimer disease, Junxiang Yin, Eric M. Reiman, Thomas G. Beach, Geidy E. Serrano, Marwan N. Sabbagh, Megan Nielsen, Richard J. Caselli, and Jiong Shi
Alterations of the GH/IGF-I Axis and Gut Microbiome after Traumatic Brain Injury: A New Clinical Syndrome?, Kevin C J Yuen, Brent E Masel, Kent L Reifschneider, Melinda Sheffield-Moore, Randall J Urban, and Richard B Pyles
Fellowship Match Outcomes in the U.S. From 2010 to 2017: Analysis of San Francisco Match, Sidra Zafar, Neil M. Bressler, Karl C. Golnik, Divya Srikumaran, Zara Ghous, Samantha Ip, Xinyi Chen, and Fasika A. Woreta
Amyloid accumulation in Down syndrome measured with amyloid load, Matthew D. Zammit, Charles M. Laymon, Tobey J. Betthauser, Karly A. Cody, Dana L. Tudorascu, Davneet S. Minhas, Marwan N. Sabbagh, Sterling C. Johnson, Shahid H. Zaman, Chester A. Mathis, William E. Klunk, Benjamin L. Handen, Ann D. Cohen, and Bradley T. Christian
Purine metabolism regulates DNA repair and therapy resistance in glioblastoma, Weihua Zhou, Yangyang Yao, Andrew J. Scott, Kari Wilder-Romans, Joseph J. Dresser, Christian K. Werner, Hanshi Sun, Drew Pratt, Peter Sajjakulnukit, Shuang G. Zhao, Mary Davis, Barbara S. Nelson, Christopher J. Halbrook, Li Zhang, Francesco Gatto, Yoshie Umemura, Angela K. Walker, Maureen Kachman, Jann N. Sarkaria, Jianping Xiong, Meredith A. Morgan, Alnawaz Rehemtualla, Maria G. Castro, Pedro Lowenstein, Sriram Chandrasekaran, Theodore S. Lawrence, Costas A. Lyssiotis, and Daniel R. Wahl
Clinical time course of COVID-19, its neurological manifestation and some thoughts on its management, Yifan Zhou, Wei Li, David Wang, Ling Mao, Huijuan Jin, Yanan Li, Candong Hong, Shengcai Chen, Jiang Chang, Quanwei He, Mengdie Wang, and Bo Hu
Cerebral Edema in Traumatic Brain Injury: a Historical Framework for Current Therapy, Benjamin E. Zusman, Patrick M. Kochanek, and Ruchira M. Jha
Submissions from 2019
Unified staging system for Lewy body disorders: Clinicopathologic correlations and comparison to Braak staging, Charles H. Adler, Thomas G. Beach, Nan Zhang, Holly A. Shill, Erika Driver-Dunckley, John N. Caviness, Shyamal H. Mehta, Marwan N. Sabbagh, Geidy E. Serrano, Lucia I. Sue, Christine M. Belden, Jessica Powell, Sandra A. Jacobson, Edward Zamrini, David Shprecher, Kathryn J. Davis, Brittany N. Dugger, and Joseph G. Hentz
ALS Drug Development Guidances and Trial Guidelines: Consensus and Opportunities for Alignment, Jinsy A. Andrews, Lucie I. Bruijn, and Jeremy M. Shefner
The reproducibility of urinary ions in manganese exposed workers, Marissa G. Baker, Yvonne S. Lin, Christopher D. Simpson, Laura M. Shireman, Susan Searles Nielsen, Brad A. Racette, and Noah Seixas
A clinical trial of enteral Levetiracetam for acute seizures in pediatric cerebral malaria, Gretchen L. Birbeck, Susan T. Herman, Edmund V. Capparelli, Fraction K. Dzinjalamala, Samah G. Abdel Baki, MacPherson Mallewa, Neema M. Toto, Douglas G. Postels, Joseph C. Gardiner, Terrie E. Taylor, and Karl B. Seydel
Excessive Daytime Sleepiness in Major Dementia Syndromes, Angelica Boeve, Tanis J. Ferman, Jeremiah Aakre, Erik St. Louis, Michael Silber, Mary Machulda, Julie Fields, Neill Graff-Radford, Michelle Mielke, Yonas Geda, David Jones, Jonathon Graff-Radford, David Knopman, Ronald Petersen, and Brad Boeve
Does Informant-Based Reporting of Cognitive Symptoms Predict Amyloid Positivity on Positron Emission Tomography?, Hannah E. Brunet, Justin B. Miller, Jiong Shi, Briana Chung, Bryce Taylor Munter, and Marwan Noel Sabbagh
Diagnosing and Treating Depression in Patients with Alzheimer’s Disease, Anna D. Burke, Danielle Goldfarb, Padmaja Bollam, and Sehar Khokher
Sirtuin 3 Promotes Microglia Migration by Upregulating Cx3Cr1, Runjing Cao, Shiping Li, Junxiang Yin, Li Guo, and Jiong Shi
Clinical Outcomes Following Awake and Asleep Deep Brain Stimulation for Parkinson Disease, Tsinsue Chen, Zaman Mirzadeh, Kristina M. Chapple, Margaret Lambert, Holly A. Shill, Guillermo Moguel-Cobos, Alexander I. Tröster, Rohit Dhall, and Francisco A. Ponce
Pediatric and adult H3 K27M-mutant diffuse midline glioma treated with the selective DRD2 antagonist ONC201, Andrew S. Chi, Rohinton S. Tarapore, Matthew D. Hall, Nicole Shonka, Sharon Gardner, Yoshie Umemura, Ashley Sumrall, Ziad Khatib, Sabine Mueller, Cassie Kline, Wafik Zaky, Soumen Khatua, Shiao-Pei Weathers, Yazmin Odia, Toba N. Niazi, Doured Daghistani, Irene Cherrick, David Korones, Matthias A. Karajannis, Xiao-Tang Kong, Jane Minturn, Angela Waanders, Isabel Arillaga-Romany, Tracy Batchelor, Patrick Y. Wen, Krystal Merdinger, Lee Schalop, Martin Stogniew, Joshua E. Allen, Wolfgang Oster, and Minesh P. Mehta
Long-Term Storage Effects on Stability of Aβ, Aβ, and Total Tau Proteins in Human Plasma Samples Measured with Immunomagnetic Reduction Assays, Ming-Jang Chiu, Lih-Fen Lue, Marwan N. Sabbagh, Ta-Fu Chen, H H. Chen, and Shieh-Yueh Yang
Thymectomy may not be associated with clinical improvement in MuSK myasthenia gravis, Katherine M. Clifford, Lisa D. Hobson-Webb, Michael Benatar, Ted M. Burns, Carolina Barnett, Nicholas J. Silvestri, James F. Howard, Amy Visser, Brian A. Crum, Richard Nowak, Rachel Beekman, Aditya Kumar, Katherine Ruzhansky, I-Hweii Amy Chen, Michael T. Pulley, Shannon M. Laboy, Melissa A. Fellman, Diantha B. Howard, Noah A. Kolb, Shane M. Greene, Mamatha Pasnoor, Mazen M. Dimachkie, Richard J. Barohn, and Michael K. Hehir
Mifepristone Treatment in Four Cases of Primary Bilateral Macronodular Adrenal Hyperplasia (BMAH)., Pejman Cohan, Honey E East, Sandi-Jo Galati, Jennifer U Mercado, Precious J Lim, Michele Lamerson, James J Smith, Anne L Peters, and Kevin C J Yuen
MRI Signal Intensity and Parkinsonism in Manganese-Exposed Workers, Susan R. Criswell, Susan Searles Nielsen, Mark N. Warden, Hubert P. Flores, Jason Lenox-Krug, Sophia Racette, Lianne Sheppard, Harvey Checkoway, and Brad A. Racette
Alzheimer's disease drug development pipeline: 2019, Jeffrey Cummings, Garam Lee, Aaron Ritter, Marwan Sabbagh, and Kate Zhong
Ophthalmic simulated surgical competency assessment rubric (Sim-OSSCAR) for trabeculectomy, William H. Dean, John Buchan, Fisseha Admassu, Min J. Kim, Karl C. Golnik, Andrew McNaught, and Matthew Burton
Ophthalmic Simulated Surgical Competency Assessment Rubric for manual small-incision cataract surgery, William H. Dean, Neil L. Murray, John C. Buchan, Karl Golnik, Min J. Kim, and Matthew J. Burton
Fornix-region deep brain stimulation–induced memory flashbacks in Alzheimer’s disease, Wissam Deeb, Bryan Salvato, Leonardo Almeida, Kelly D. Foote, Robert Amaral, Jurgen Germann, Paul B. Rosenberg, David F. Tang-Wai, David A. Wolk, Anna D. Burke, Stephen Salloway, Marwan N. Sabbagh, M. Mallar Chakravarty, Gwenn S. Smith, Constantine G. Lyketsos, Andres M. Lozano, and Michael S. Okun
Brain Lewy-Type Synucleinopathy Density is Associated With a Lower Prevalence of Atherosclerotic Cardiovascular Disease Risk Factors in Patients With Parkinson's Disease, Erika D. Driver-Dunckley, Nan Zhang, Charles H. Adler, Geidy E. Serrano, Lucia I. Sue, Holly A. Shill, Shyamal H. Mehta, Christine M. Belden, Edward Y. Zamrini, Kathryn Davis, and Thomas G. Beach
Tau Immunoreactivity in Peripheral Tissues of Human Aging and Select Tauopathies, Brittany N. Dugger, Brittany R. Hoffman, Alex Scroggins, Geidy E. Serrano, Charles H. Adler, Holly A. Shill, Christine M. Belden, Marwan N. Sabbagh, John N. Caviness, Erika Driver Dunckley, and Thomas G. Beach
The Current State of Molecular Testing in the Treatment of Patients With Solid Tumors 2019, Wafik S. El-Deiry, Richard M. Goldberg, Heinz Josef Lenz, Anthony F. Shields, Geoffrey T. Gibney, Antoinette R. Tan, Jubilee Brown, Burton Eisenberg, Elisabeth I. Heath, Surasak Phuphanich, Edward Kim, Andrew J. Brenner, and John L. Marshall
Regional Neuropathology Distribution and Verbal Fluency Impairments in Parkinson's Disease, Rasheda El-Nazer, Charles H. Adler, Thomas G. Beach, Christine M. Belden, Jonathan Artz, Holly A. Shill, Erika Driver-Dunckley, Shyamal H. Mehta, Marwan N. Sabbagh, Geidy E. Serrano, Lucia I. Sue, Edward Zamrini, and Jared F. Benge
Transplant and risk of Parkinson disease, Jessica Fan, Susan Searles Nielsen, Irene M. Faust, and Brad A. Racette
Age-Related Atrophy and Compensatory Neural Networks in Reading Comprehension, Megan C. Fitzhugh, B. Blair Braden, Marwan N. Sabbagh, Corianne Rogalsky, and Leslie C. Baxter
Brain-Derived Neurotrophic Factor and Its Associations with Metabolism and Physical Activity in a Latino Sample, Rodrigo Fonseca-Portilla, Janina Krell-Roesch, Gabriel Q. Shaibi, Richard J. Caselli, Lawrence J. Mandarino, Nan Zhang, Joseph G. Hentz, Dawn K. Coletta, Elena Anna De Filippis, Sara Dawit, and Yonas E. Geda
Quality improvement in neurology: Mild cognitive impairment quality measurement set, Norman L. Foster, Mark W. Bondi, Rohit Das, Mary Foss, Linda A. Hershey, Steve Koh, Rebecca Logan, Carol Poole, Joseph W. Shega, Ajay Sood, Niranjan Thothala, Meredith Wicklund, Melissa Yu, Amy Bennett, and David Wang
The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory, Nicolai Franzmeier, Anna Rubinski, Julia Neitzel, Michael Ewers, Michael W. Weiner, Paul Aisen, Ronald Petersen, Clifford R. Jack, William Jagust, John Q. Trojanowski, Arthur W. Toga, Laurel Beckett, Robert C. Green, Andrew J. Saykin, John Morris, Leslie M. Shaw, Zaven Khachaturian, Greg Sorensen, Lew Kuller, Marcus Raichle, Steven Paul, Peter Davies, Howard Fillit, Franz Hefti, David Holtzman, Marek M. Mesulam, William Potter, Peter Snyder, Adam Schwartz, Tom Montine, Ronald G. Thomas, and Michael Donohue
Combination Therapy for Alzheimer's Disease: Perspectives of the EU/US CTAD Task Force, S. Gauthier, J. Alam, H. Fillit, T. Iwatsubo, H. Liu-Seifert, M. Sabbagh, S. Salloway, C. Sampaio, J. R. Sims, B. Sperling, R. Sperling, K. A. Welsh-Bohmer, J. Touchon, B. Vellas, and P. Aisen
Quantitative Electroencephalogram Trends Predict Recovery in Hypoxic-Ischemic Encephalopathy, Mohammad M. Ghassemi, Edilberto Amorim, Tuka Alhanai, Jong W. Lee, Susan T. Herman, Adithya Sivaraju, Nicolas Gaspard, Lawrence J. Hirsch, Benjamin M. Scirica, Siddharth Biswal, Valdery Moura Junior, Sydney S. Cash, Emery N. Brown, Roger G. Mark, and M. Brandon Westover
A blood-based signature of cerebrospinal fluid Aβ 1–42 status, Benjamin Goudey, Bowen J. Fung, Christine Schieber, Noel G. Faux, Michael W. Weiner, Paul Aisen, Ronald Petersen, Clifford R. Jack, William Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, Andrew J. Saykin, John C. Morris, Leslie M. Shaw, Jeffrey Kaye, Joseph Quinn, Lisa Silbert, Betty Lind, Raina Carter, Sara Dolen, Lon S. Schneider, Sonia Pawluczyk, Mauricio Beccera, Liberty Teodoro, Bryan M. Spann, James Brewer, and Helen Vanderswag
Present Algorithms and Future Treatments for Alzheimer's Disease, George T. Grossberg, Gary Tong, Anna D. Burke, and Pierre N. Tariot
Mifepristone Increases Thyroid Hormone Requirements in Patients With Central Hypothyroidism: A Multicenter Study., Francisco J Guarda, James Findling, Kevin C J Yuen, Maria Fleseriu, and Lisa B Nachtigall
Deep brain stimulation and cognitive outcomes among patients with Parkinson’s disease: A historical cohort study, Allison L. Hansen, Janina Krell-Roesch, Kristin A. Kirlin, Martin M. Limback-Stokin, Kimberly Roesler, Stefanie N. Velgos, Mark K. Lyons, Yonas E. Geda, and Shyamal H. Mehta
Prevalence of Dyskinesia and Off by 30-Minute Intervals Through the Day and Assessment of Daily Episodes of Dyskinesia and Off: Novel Analyses of Diary Data From Gocovri Pivotal Trials, Robert A. Hauser, Daniel E. Kremens, Lawrence W. Elmer, David L. Kreitzman, Ryan R. Walsh, Reed Johnson, Robert Howard, Jack T. Nguyen, and Rajiv Patni
Multimodal Hippocampal Subfield Grading For Alzheimer’s Disease Classification, Kilian Hett, Vinh Thong Ta, Gwenaëlle Catheline, Thomas Tourdias, José V. Manjón, Pierrick Coupé, Michael W. Weiner, Paul Aisen, Ronald Petersen, Clifford R. Jack, William Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, Andrew J. Saykin, John Morris, Leslie M. Shaw, Zaven Khachaturian, Greg Sorensen, Maria Carrillo, Lew Kuller, Marc Raichle, Steven Paul, Peter Davies, Howard Fillit, Franz Hefti, Davie Holtzman, and M. Marcel Mesulam
Genome-wide association analysis of hippocampal volume identifies enrichment of neurogenesis-related pathways, Emrin Horgusluoglu-Moloch, Shannon L. Risacher, Paul K. Crane, Derrek Hibar, Paul M. Thompson, Andrew J. Saykin, Kwangsik Nho, Michael W. Weiner, Paul Aisen, Ronald Petersen, Clifford R. Jack, William Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, John C. Morris, Leslie M. Shaw, Jeffrey Kaye, Joseph Quinn, Lisa Silbert, Betty Lind, Raina Carter, Sara Dolen, Lon S. Schneider, Sonia Pawluczyk, Mauricio Beccera, Liberty Teodoro, and Bryan M. Spann
Nicotinic acetylcholine receptor agonists for the treatment of Alzheimer's dementia: An update, Justin L. Hoskin, Yazan Al-Hasan, and Marwan Noel Sabbagh
Tau immunotherapies for Alzheimer's disease, Justin L. Hoskin, Marwan Noel Sabbagh, Yazan Al-Hasan, and Boris Decourt
Downstream Polymorphisms Are Associated with Intracranial Hypertension and Statistically Interact with Polymorphisms in a Prospective Cohort of Severe Traumatic Brain Injury, Ruchira M. Jha, Shashvat M. Desai, Benjamin E. Zusman, Theresa A. Koleck, Ava M. Puccio, David O. Okonkwo, Seo-Young Park, Lori A. Shutter, Patrick M. Kochanek, and Yvette P. Conley
Arresting edema: Important after anoxic brain injury?, Ruchira M. Jha and Jonathan Elmer
Transcranial dopplers after cardiac arrest: Should we ride this wave?, Ruchira M. Jha and Jonathan Elmer
Pathophysiology and treatment of cerebral edema in traumatic brain injury, Ruchira M. Jha, Patrick M. Kochanek, and J Marc Simard
Vertical and Radial Attentional Neglect in Corticobasal Syndrome, Parunyou Julayanont, David W. Burks, and Kenneth M. Heilman
Polypharmacy in an Elderly Population: Enhancing Medication Management Through the Use of Clinical Decision Support Software Platforms, Dorothy Keine, Mark Zelek, John Q. Walker, and Marwan N. Sabbagh
Bilateral Recurrent Dysplastic Cerebellar Gangliocytoma (Lhermitte-Duclos Disease) in Cowden Syndrome: A Case Report and Literature Review, Umang Khandpur, Kristin Huntoon, Matthew Smith-Cohn, Andrew Shaw, and James Bradley Elder
Dose-intensified chemoradiation is associated with altered patterns of failure and favorable survival in patients with newly diagnosed glioblastoma, Michelle M. Kim, Corey Speers, Pin Li, Matthew Schipper, Larry Junck, Denise Leung, Daniel Orringer, Jason Heth, Yoshie Umemura, Daniel E. Spratt, Daniel R. Wahl, Yue Cao, Theodore S. Lawrence, and Christina I. Tsien
Functional activity and neuropsychiatric symptoms in normal aging and mild cognitive impairment: The Mayo clinic study of aging, Janina Krell-Roesch, Leah P. Cerhan, Mary M. MacHulda, Rosebud O. Roberts, Michelle M. Mielke, David S. Knopman, Jeremy A. Syrjanen, Teresa J. Christianson, Ronald C. Petersen, and Yonas E. Geda
Association of non-exercise physical activity in mid- and late-life with cognitive trajectories and the impact of APOE ε4 genotype status: the Mayo Clinic Study of Aging, Janina Krell-Roesch, Jeremy A. Syrjanen, Maria Vassilaki, Bettina Barisch-Fritz, Sandra Trautwein, Klaus Boes, Alexander Woll, Walter K. Kremers, Mary M. Machulda, Michelle M. Mielke, David S. Knopman, Ronald C. Petersen, and Yonas E. Geda
Quantity and quality of mental activities and the risk of incident mild cognitive impairment, Janina Krell-Roesch, Jeremy A. Syrjanen, Maria Vassilaki, Mary M. MacHulda, Michelle M. Mielke, David S. Knopman, Walter K. Kremers, Ronald C. Petersen, and Yonas E. Geda
Cortical β-amyloid burden, neuropsychiatric symptoms, and cognitive status: the Mayo Clinic Study of Aging, Janina Krell-Roesch, Maria Vassilaki, Michelle M. Mielke, Walter K. Kremers, Val J. Lowe, Prashanthi Vemuri, Mary M. Machulda, Teresa J. Christianson, Jeremy A. Syrjanen, Gorazd B. Stokin, Lesley M. Butler, Martin Traber, Clifford R. Jack, David S. Knopman, Rosebud O. Roberts, Ronald C. Petersen, and Yonas E. Geda
Use of a Geographic Information System to create treatment groups for group-randomized community trials: The Minnesota Heart Health Program., Brittany Krzyzanowski, Steven M Manson, Milton Mickey Eder, Len Kne, Niki Oldenburg, Kevin Peterson, Alan T Hirsch, Russell V Luepker, and Sue Duval
Use of a Geographic Information System to create treatment groups for group-randomized community trials: The Minnesota Heart Health Program, Brittany Krzyzanowski, Steven M. Manson, Milton Mickey Eder, Len Kne, Niki Oldenburg, Kevin Peterson, Alan T. Hirsch, Russell V. Luepker, and Sue Duval
Assessing Postconcussive Reaction Time Using Transport-Based Morphometry of Diffusion Tensor Images., S Kundu, A Ghodadra, S Fakhran, L M Alhilali, and G K Rohde
A Novel Joint Brain Network Analysis Using Longitudinal Alzheimer’s Disease Data, Suprateek Kundu, Joshua Lukemire, Yikai Wang, Ying Guo, Michael W. Weiner, Norbert Schuff, Howard J. Rosen, Bruce L. Miller, Thomas Neylan, Jacqueline Hayes, Shannon Finley, Paul Aisen, Zaven Khachaturian, Ronald G. Thomas, Michael Donohue, Sarah Walter, Devon Gessert, Tamie Sather, Gus Jiminez, Leon Thal, James Brewer, Helen Vanderswag, Adam Fleisher, Melissa Davis, Rosemary Morrison, Ronald Petersen, Clifford R. Jack, Matthew Bernstein, Bret Borowski, Jeff Gunter, Matt Senjem, and Prashanthi Vemuri