The Barrow Neurological Institute is proud of its reputation as a medical research facility and is home to some of the most sophisticated research programs outside of an academic setting in the Southwestern United States. Researchers in the Barrow Neurosurgery Research Center are devoted to learning more about the causes of and treatments for a wide range of disorders, such as stroke, aneurysms, spinal cord injury, and hydrocephalus. Our research has led to treatments that are being used around the world. Within the Department are neurosurgeons who subspecialize in cerebrovascular and skull base, functional and stereotactic, pediatric, spine, tumor, and endovascular neurosurgery.
Physicians, scientists, and expert clinical staff come together with a commitment to developing new techniques for the prevention, diagnosis, treatment, and rehabilitation of neurological illnesses and injuries. The leadership of internationally respected physicians keeps Barrow at the forefront of neuroscience. The compassionate expertise of its extensive staff of nurses, technologists, therapists and support personnel is evident in every aspect of care provided.
Our mission is to advance the knowledge and practice of medicine in neuroscience through basic and clinical research, education of medical professionals, and innovation in clinical techniques and technology.
Submissions from 2019
ALS Drug Development Guidances and Trial Guidelines: Consensus and Opportunities for Alignment, Jinsy A. Andrews, Lucie I. Bruijn, and Jeremy M. Shefner
The reproducibility of urinary ions in manganese exposed workers, Marissa G. Baker, Yvonne S. Lin, Christopher D. Simpson, Laura M. Shireman, Susan Searles Nielsen, Brad A. Racette, and Noah Seixas
A clinical trial of enteral Levetiracetam for acute seizures in pediatric cerebral malaria, Gretchen L. Birbeck, Susan T. Herman, Edmund V. Capparelli, Fraction K. Dzinjalamala, Samah G. Abdel Baki, MacPherson Mallewa, Neema M. Toto, Douglas G. Postels, Joseph C. Gardiner, Terrie E. Taylor, and Karl B. Seydel
Excessive Daytime Sleepiness in Major Dementia Syndromes, Angelica Boeve, Tanis J. Ferman, Jeremiah Aakre, Erik St. Louis, Michael Silber, Mary Machulda, Julie Fields, Neill Graff-Radford, Michelle Mielke, Yonas Geda, David Jones, Jonathon Graff-Radford, David Knopman, Ronald Petersen, and Brad Boeve
Does Informant-Based Reporting of Cognitive Symptoms Predict Amyloid Positivity on Positron Emission Tomography?, Hannah E. Brunet, Justin B. Miller, Jiong Shi, Briana Chung, Bryce Taylor Munter, and Marwan Noel Sabbagh
Diagnosing and Treating Depression in Patients with Alzheimer’s Disease, Anna D. Burke, Danielle Goldfarb, Padmaja Bollam, and Sehar Khokher
Sirtuin 3 Promotes Microglia Migration by Upregulating Cx3Cr1, Runjing Cao, Shiping Li, Junxiang Yin, Li Guo, and Jiong Shi
Clinical Outcomes Following Awake and Asleep Deep Brain Stimulation for Parkinson Disease, Tsinsue Chen, Zaman Mirzadeh, Kristina M. Chapple, Margaret Lambert, Holly A. Shill, Guillermo Moguel-Cobos, Alexander I. Tröster, Rohit Dhall, and Francisco A. Ponce
Pediatric and adult H3 K27M-mutant diffuse midline glioma treated with the selective DRD2 antagonist ONC201, Andrew S. Chi, Rohinton S. Tarapore, Matthew D. Hall, Nicole Shonka, Sharon Gardner, Yoshie Umemura, Ashley Sumrall, Ziad Khatib, Sabine Mueller, Cassie Kline, Wafik Zaky, Soumen Khatua, Shiao-Pei Weathers, Yazmin Odia, Toba N. Niazi, Doured Daghistani, Irene Cherrick, David Korones, Matthias A. Karajannis, Xiao-Tang Kong, Jane Minturn, Angela Waanders, Isabel Arillaga-Romany, Tracy Batchelor, Patrick Y. Wen, Krystal Merdinger, Lee Schalop, Martin Stogniew, Joshua E. Allen, Wolfgang Oster, and Minesh P. Mehta
Long-Term Storage Effects on Stability of Aβ, Aβ, and Total Tau Proteins in Human Plasma Samples Measured with Immunomagnetic Reduction Assays, Ming-Jang Chiu, Lih-Fen Lue, Marwan N. Sabbagh, Ta-Fu Chen, H H. Chen, and Shieh-Yueh Yang
Thymectomy may not be associated with clinical improvement in MuSK myasthenia gravis, Katherine M. Clifford, Lisa D. Hobson-Webb, Michael Benatar, Ted M. Burns, Carolina Barnett, Nicholas J. Silvestri, James F. Howard, Amy Visser, Brian A. Crum, Richard Nowak, Rachel Beekman, Aditya Kumar, Katherine Ruzhansky, I-Hweii Amy Chen, Michael T. Pulley, Shannon M. Laboy, Melissa A. Fellman, Diantha B. Howard, Noah A. Kolb, Shane M. Greene, Mamatha Pasnoor, Mazen M. Dimachkie, Richard J. Barohn, and Michael K. Hehir
Mifepristone Treatment in Four Cases of Primary Bilateral Macronodular Adrenal Hyperplasia (BMAH)., Pejman Cohan, Honey E East, Sandi-Jo Galati, Jennifer U Mercado, Precious J Lim, Michele Lamerson, James J Smith, Anne L Peters, and Kevin C J Yuen
MRI Signal Intensity and Parkinsonism in Manganese-Exposed Workers, Susan R. Criswell, Susan Searles Nielsen, Mark N. Warden, Hubert P. Flores, Jason Lenox-Krug, Sophia Racette, Lianne Sheppard, Harvey Checkoway, and Brad A. Racette
Alzheimer's disease drug development pipeline: 2019, Jeffrey Cummings, Garam Lee, Aaron Ritter, Marwan Sabbagh, and Kate Zhong
Ophthalmic simulated surgical competency assessment rubric (Sim-OSSCAR) for trabeculectomy, William H. Dean, John Buchan, Fisseha Admassu, Min J. Kim, Karl C. Golnik, Andrew McNaught, and Matthew Burton
Ophthalmic Simulated Surgical Competency Assessment Rubric for manual small-incision cataract surgery, William H. Dean, Neil L. Murray, John C. Buchan, Karl Golnik, Min J. Kim, and Matthew J. Burton
Fornix-region deep brain stimulation–induced memory flashbacks in Alzheimer’s disease, Wissam Deeb, Bryan Salvato, Leonardo Almeida, Kelly D. Foote, Robert Amaral, Jurgen Germann, Paul B. Rosenberg, David F. Tang-Wai, David A. Wolk, Anna D. Burke, Stephen Salloway, Marwan N. Sabbagh, M. Mallar Chakravarty, Gwenn S. Smith, Constantine G. Lyketsos, Andres M. Lozano, and Michael S. Okun
Brain Lewy-Type Synucleinopathy Density is Associated With a Lower Prevalence of Atherosclerotic Cardiovascular Disease Risk Factors in Patients With Parkinson's Disease, Erika D. Driver-Dunckley, Nan Zhang, Charles H. Adler, Geidy E. Serrano, Lucia I. Sue, Holly A. Shill, Shyamal H. Mehta, Christine M. Belden, Edward Y. Zamrini, Kathryn Davis, and Thomas G. Beach
Tau Immunoreactivity in Peripheral Tissues of Human Aging and Select Tauopathies, Brittany N. Dugger, Brittany R. Hoffman, Alex Scroggins, Geidy E. Serrano, Charles H. Adler, Holly A. Shill, Christine M. Belden, Marwan N. Sabbagh, John N. Caviness, Erika Driver Dunckley, and Thomas G. Beach
The Current State of Molecular Testing in the Treatment of Patients With Solid Tumors 2019, Wafik S. El-Deiry, Richard M. Goldberg, Heinz Josef Lenz, Anthony F. Shields, Geoffrey T. Gibney, Antoinette R. Tan, Jubilee Brown, Burton Eisenberg, Elisabeth I. Heath, Surasak Phuphanich, Edward Kim, Andrew J. Brenner, and John L. Marshall
Regional Neuropathology Distribution and Verbal Fluency Impairments in Parkinson's Disease, Rasheda El-Nazer, Charles H. Adler, Thomas G. Beach, Christine M. Belden, Jonathan Artz, Holly A. Shill, Erika Driver-Dunckley, Shyamal H. Mehta, Marwan N. Sabbagh, Geidy E. Serrano, Lucia I. Sue, Edward Zamrini, and Jared F. Benge
Transplant and risk of Parkinson disease, Jessica Fan, Susan Searles Nielsen, Irene M. Faust, and Brad A. Racette
Age-Related Atrophy and Compensatory Neural Networks in Reading Comprehension, Megan C. Fitzhugh, B. Blair Braden, Marwan N. Sabbagh, Corianne Rogalsky, and Leslie C. Baxter
Brain-Derived Neurotrophic Factor and Its Associations with Metabolism and Physical Activity in a Latino Sample, Rodrigo Fonseca-Portilla, Janina Krell-Roesch, Gabriel Q. Shaibi, Richard J. Caselli, Lawrence J. Mandarino, Nan Zhang, Joseph G. Hentz, Dawn K. Coletta, Elena Anna De Filippis, Sara Dawit, and Yonas E. Geda
Quality improvement in neurology: Mild cognitive impairment quality measurement set, Norman L. Foster, Mark W. Bondi, Rohit Das, Mary Foss, Linda A. Hershey, Steve Koh, Rebecca Logan, Carol Poole, Joseph W. Shega, Ajay Sood, Niranjan Thothala, Meredith Wicklund, Melissa Yu, Amy Bennett, and David Wang
The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory, Nicolai Franzmeier, Anna Rubinski, Julia Neitzel, Michael Ewers, Michael W. Weiner, Paul Aisen, Ronald Petersen, Clifford R. Jack, William Jagust, John Q. Trojanowski, Arthur W. Toga, Laurel Beckett, Robert C. Green, Andrew J. Saykin, John Morris, Leslie M. Shaw, Zaven Khachaturian, Greg Sorensen, Lew Kuller, Marcus Raichle, Steven Paul, Peter Davies, Howard Fillit, Franz Hefti, David Holtzman, Marek M. Mesulam, William Potter, Peter Snyder, Adam Schwartz, Tom Montine, Ronald G. Thomas, and Michael Donohue
Combination Therapy for Alzheimer's Disease: Perspectives of the EU/US CTAD Task Force, S. Gauthier, J. Alam, H. Fillit, T. Iwatsubo, H. Liu-Seifert, M. Sabbagh, S. Salloway, C. Sampaio, J. R. Sims, B. Sperling, R. Sperling, K. A. Welsh-Bohmer, J. Touchon, B. Vellas, and P. Aisen
Quantitative Electroencephalogram Trends Predict Recovery in Hypoxic-Ischemic Encephalopathy, Mohammad M. Ghassemi, Edilberto Amorim, Tuka Alhanai, Jong W. Lee, Susan T. Herman, Adithya Sivaraju, Nicolas Gaspard, Lawrence J. Hirsch, Benjamin M. Scirica, Siddharth Biswal, Valdery Moura Junior, Sydney S. Cash, Emery N. Brown, Roger G. Mark, and M. Brandon Westover
A blood-based signature of cerebrospinal fluid Aβ 1–42 status, Benjamin Goudey, Bowen J. Fung, Christine Schieber, Noel G. Faux, Michael W. Weiner, Paul Aisen, Ronald Petersen, Clifford R. Jack, William Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, Andrew J. Saykin, John C. Morris, Leslie M. Shaw, Jeffrey Kaye, Joseph Quinn, Lisa Silbert, Betty Lind, Raina Carter, Sara Dolen, Lon S. Schneider, Sonia Pawluczyk, Mauricio Beccera, Liberty Teodoro, Bryan M. Spann, James Brewer, and Helen Vanderswag
Present Algorithms and Future Treatments for Alzheimer's Disease, George T. Grossberg, Gary Tong, Anna D. Burke, and Pierre N. Tariot
Mifepristone Increases Thyroid Hormone Requirements in Patients With Central Hypothyroidism: A Multicenter Study., Francisco J Guarda, James Findling, Kevin C J Yuen, Maria Fleseriu, and Lisa B Nachtigall
Deep brain stimulation and cognitive outcomes among patients with Parkinson’s disease: A historical cohort study, Allison L. Hansen, Janina Krell-Roesch, Kristin A. Kirlin, Martin M. Limback-Stokin, Kimberly Roesler, Stefanie N. Velgos, Mark K. Lyons, Yonas E. Geda, and Shyamal H. Mehta
Prevalence of Dyskinesia and Off by 30-Minute Intervals Through the Day and Assessment of Daily Episodes of Dyskinesia and Off: Novel Analyses of Diary Data From Gocovri Pivotal Trials, Robert A. Hauser, Daniel E. Kremens, Lawrence W. Elmer, David L. Kreitzman, Ryan R. Walsh, Reed Johnson, Robert Howard, Jack T. Nguyen, and Rajiv Patni
Multimodal Hippocampal Subfield Grading For Alzheimer’s Disease Classification, Kilian Hett, Vinh Thong Ta, Gwenaëlle Catheline, Thomas Tourdias, José V. Manjón, Pierrick Coupé, Michael W. Weiner, Paul Aisen, Ronald Petersen, Clifford R. Jack, William Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, Andrew J. Saykin, John Morris, Leslie M. Shaw, Zaven Khachaturian, Greg Sorensen, Maria Carrillo, Lew Kuller, Marc Raichle, Steven Paul, Peter Davies, Howard Fillit, Franz Hefti, Davie Holtzman, and M. Marcel Mesulam
Genome-wide association analysis of hippocampal volume identifies enrichment of neurogenesis-related pathways, Emrin Horgusluoglu-Moloch, Shannon L. Risacher, Paul K. Crane, Derrek Hibar, Paul M. Thompson, Andrew J. Saykin, Kwangsik Nho, Michael W. Weiner, Paul Aisen, Ronald Petersen, Clifford R. Jack, William Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, John C. Morris, Leslie M. Shaw, Jeffrey Kaye, Joseph Quinn, Lisa Silbert, Betty Lind, Raina Carter, Sara Dolen, Lon S. Schneider, Sonia Pawluczyk, Mauricio Beccera, Liberty Teodoro, and Bryan M. Spann
Nicotinic acetylcholine receptor agonists for the treatment of Alzheimer's dementia: An update, Justin L. Hoskin, Yazan Al-Hasan, and Marwan Noel Sabbagh
Tau immunotherapies for Alzheimer's disease, Justin L. Hoskin, Marwan Noel Sabbagh, Yazan Al-Hasan, and Boris Decourt
Downstream Polymorphisms Are Associated with Intracranial Hypertension and Statistically Interact with Polymorphisms in a Prospective Cohort of Severe Traumatic Brain Injury, Ruchira M. Jha, Shashvat M. Desai, Benjamin E. Zusman, Theresa A. Koleck, Ava M. Puccio, David O. Okonkwo, Seo-Young Park, Lori A. Shutter, Patrick M. Kochanek, and Yvette P. Conley
Arresting edema: Important after anoxic brain injury?, Ruchira M. Jha and Jonathan Elmer
Transcranial dopplers after cardiac arrest: Should we ride this wave?, Ruchira M. Jha and Jonathan Elmer
Pathophysiology and treatment of cerebral edema in traumatic brain injury, Ruchira M. Jha, Patrick M. Kochanek, and J Marc Simard
Vertical and Radial Attentional Neglect in Corticobasal Syndrome, Parunyou Julayanont, David W. Burks, and Kenneth M. Heilman
Polypharmacy in an Elderly Population: Enhancing Medication Management Through the Use of Clinical Decision Support Software Platforms, Dorothy Keine, Mark Zelek, John Q. Walker, and Marwan N. Sabbagh
Bilateral Recurrent Dysplastic Cerebellar Gangliocytoma (Lhermitte-Duclos Disease) in Cowden Syndrome: A Case Report and Literature Review, Umang Khandpur, Kristin Huntoon, Matthew Smith-Cohn, Andrew Shaw, and James Bradley Elder
Dose-intensified chemoradiation is associated with altered patterns of failure and favorable survival in patients with newly diagnosed glioblastoma, Michelle M. Kim, Corey Speers, Pin Li, Matthew Schipper, Larry Junck, Denise Leung, Daniel Orringer, Jason Heth, Yoshie Umemura, Daniel E. Spratt, Daniel R. Wahl, Yue Cao, Theodore S. Lawrence, and Christina I. Tsien
Functional activity and neuropsychiatric symptoms in normal aging and mild cognitive impairment: The Mayo clinic study of aging, Janina Krell-Roesch, Leah P. Cerhan, Mary M. MacHulda, Rosebud O. Roberts, Michelle M. Mielke, David S. Knopman, Jeremy A. Syrjanen, Teresa J. Christianson, Ronald C. Petersen, and Yonas E. Geda
Association of non-exercise physical activity in mid- and late-life with cognitive trajectories and the impact of APOE ε4 genotype status: the Mayo Clinic Study of Aging, Janina Krell-Roesch, Jeremy A. Syrjanen, Maria Vassilaki, Bettina Barisch-Fritz, Sandra Trautwein, Klaus Boes, Alexander Woll, Walter K. Kremers, Mary M. Machulda, Michelle M. Mielke, David S. Knopman, Ronald C. Petersen, and Yonas E. Geda
Quantity and quality of mental activities and the risk of incident mild cognitive impairment, Janina Krell-Roesch, Jeremy A. Syrjanen, Maria Vassilaki, Mary M. MacHulda, Michelle M. Mielke, David S. Knopman, Walter K. Kremers, Ronald C. Petersen, and Yonas E. Geda
Cortical β-amyloid burden, neuropsychiatric symptoms, and cognitive status: the Mayo Clinic Study of Aging, Janina Krell-Roesch, Maria Vassilaki, Michelle M. Mielke, Walter K. Kremers, Val J. Lowe, Prashanthi Vemuri, Mary M. Machulda, Teresa J. Christianson, Jeremy A. Syrjanen, Gorazd B. Stokin, Lesley M. Butler, Martin Traber, Clifford R. Jack, David S. Knopman, Rosebud O. Roberts, Ronald C. Petersen, and Yonas E. Geda
Use of a Geographic Information System to create treatment groups for group-randomized community trials: The Minnesota Heart Health Program., Brittany Krzyzanowski, Steven M Manson, Milton Mickey Eder, Len Kne, Niki Oldenburg, Kevin Peterson, Alan T Hirsch, Russell V Luepker, and Sue Duval
Use of a Geographic Information System to create treatment groups for group-randomized community trials: The Minnesota Heart Health Program, Brittany Krzyzanowski, Steven M. Manson, Milton Mickey Eder, Len Kne, Niki Oldenburg, Kevin Peterson, Alan T. Hirsch, Russell V. Luepker, and Sue Duval
Assessing Postconcussive Reaction Time Using Transport-Based Morphometry of Diffusion Tensor Images., S Kundu, A Ghodadra, S Fakhran, L M Alhilali, and G K Rohde
A Novel Joint Brain Network Analysis Using Longitudinal Alzheimer’s Disease Data, Suprateek Kundu, Joshua Lukemire, Yikai Wang, Ying Guo, Michael W. Weiner, Norbert Schuff, Howard J. Rosen, Bruce L. Miller, Thomas Neylan, Jacqueline Hayes, Shannon Finley, Paul Aisen, Zaven Khachaturian, Ronald G. Thomas, Michael Donohue, Sarah Walter, Devon Gessert, Tamie Sather, Gus Jiminez, Leon Thal, James Brewer, Helen Vanderswag, Adam Fleisher, Melissa Davis, Rosemary Morrison, Ronald Petersen, Clifford R. Jack, Matthew Bernstein, Bret Borowski, Jeff Gunter, Matt Senjem, and Prashanthi Vemuri
ε4 is associated with younger age at ischemic stroke onset but not with stroke outcome, Cecilia Lagging, Erik Lorentzen, Tara M. Stanne, Annie Pedersen, Martin Söderholm, John W. Cole, Katarina Jood, Robin Lemmens, Chia-Ling Phuah, Natalia S. Rost, Vincent Thijs, Daniel Woo, Jane M. Maguire, Arne Lindgren, and Christina Jern
Cerebellar Syndrome in a Man Treated With Natalizumab: From the National Multiple Sclerosis Society Case Conference Proceedings, David A. Lapides, Prem P. Batchala, Joseph H. Donahue, Robert P. Lisak, Ethan I. Meltzer, Ram N. Narayan, Avi Nath, Teresa C. Frohman, Kathleen Costello, Myla D. Goldman, Scott S. Zamvil, and Elliot M. Frohman
Clinical drug development for dementia with Lewy bodies: past and present, Garam Lee, Jeffrey Cummings, Boris Decourt, James B. Leverenz, and Marwan N. Sabbagh
Predicting Alzheimer’s disease progression using multi-modal deep learning approach, Garam Lee, Kwangsik Nho, Byungkon Kang, Kyung Ah Sohn, Dokyoon Kim, Michael W. Weiner, Paul Aisen, Ronald Petersen, Clifford R. Jack, William Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, Andrew J. Saykin, John Morris, Leslie M. Shaw, Zaven Khachaturian, Greg Sorensen, Maria Carrillo, Lew Kuller, Marc Raichle, Steven Paul, Peter Davies, Howard Fillit, Franz Hefti, Davie Holtzman, M. Marcel Mesulam, and William Potter
Nicotine Bitartrate Reduces Falls and Freezing of Gait in Parkinson Disease: A Reanalysis, Abraham N. Lieberman, Thurmon E. Lockhart, Markey C. Olson, Victoria A. Hussain, Christopher W. Frames, Arshia Sadreddin, Margaret McCauley, and Elizabeth Ludington
Sirtuin 3 Mediates Tau Deacetylation, Shiping Li, Junxiang Yin, Megan Nielsen, Thomas G. Beach, Li Guo, and Jiong Shi
Higher Hemoglobin A1c Level Is Associated With Poor Outcome of Intracerebral Hemorrhage, Huihui Liu, Xia Meng, Chun-Feng Liu, David Wang, Huaguang Zheng, Hao Li, Liping Liu, Yilong Wang, Yongjun Wang, and Yuesong Pan
Advance in Plasma AD Core Biomarker Development: Current Findings from Immunomagnetic Reduction-Based SQUID Technology, Lih Fen Lue, Yu Min Kuo, and Marwan Sabbagh
Age-Dependent Relationship Between Plasma Aβ40 and Aβ42 and Total Tau Levels in Cognitively Normal Subjects, Lih-Fen Lue, Ming-Chyi Pai, Ta-Fu Chen, Chaur-Jong Hu, Li-Kai Huang, Wei-Che Lin, Chau-Chung Wu, Jian-Shing Jeng, Kaj Blennow, Marwan N. Sabbagh, Sui-Hing Yan, Pei-Ning Wang, Shieh-Yueh Yang, Hiroyuki Hatsuta, Satoru Morimoto, Akitoshi Takeda, Yoshiaki Itoh, Jun Liu, Haiqun Xie, and Ming-Jang Chiu
Corrigendum: Age-Dependent Relationship Between Plasma Aβ40 and Aβ42 and Total Tau Levels in Cognitively Normal Subjects, Lih-Fen Lue, Ming-Chyi Pai, Ta-Fu Chen, Chaur-Jong Hu, Li-Kai Huang, Wei-Che Lin, Chau-Chung Wu, Jian-Shing Jeng, Kaj Blennow, Marwan N. Sabbagh, Sui-Hing Yan, Pei-Ning Wang, Shieh-Yueh Yang, Hiroyuki Hatsuta, Satoru Morimoto, Akitoshi Takeda, Yoshiaki Itoh, Jun Liu, Haiqun Xie, and Ming-Jang Chiu
Faster Cognitive Decline in Dementia Due to Alzheimer Disease With Clinically Undiagnosed Lewy Body Disease, Michael Malek-Ahmadi, Thomas G. Beach, Edward Zamrini, Charles H. Adler, Marwan N. Sabbagh, Holly A. Shill, Sandra A. Jacobson, Christine M. Belden, Richard J. Caselli, Brian K. Woodruff, Steven Z. Rapscak, Geoffrey L. Ahern, Jiong Shi, John N. Caviness, Erika Driver-Dunckley, Shyamal H. Mehta, David R. Shprecher, Bryan M. Spann, Pierre Tariot, and et al.
Long-term safety and efficacy of subcutaneous pasireotide in patients with Cushing's disease: interim results from a long-term real-world evidence study., Luca Manetti, Timo Deutschbein, Jochen Schopohl, Kevin C J Yuen, Michael Roughton, Ulrike Kriemler-Krahn, Libuse Tauchmanova, Ricardo Maamari, and Carla Giordano
Oxidative metabolism alterations in the emotional brain of anxiety-prone rats, Chelsea R. McCoy, Mohammad N. Sabbagh, Jonathan P. Huaman, Alicia M. Pickrell, and Sarah M. Clinton
Efficacy and safety of IVIG in CIDP: Combined data of the PRIMA and PATH studies, Ingemar S.J. Merkies, Ivo N. van Schaik, Jean Marc Léger, Vera Bril, Nan van Geloven, Hans Peter Hartung, Richard A. Lewis, Gen Sobue, John Philip Lawo, Billie L. Durn, David R. Cornblath, Jan L. De Bleecker, Claudia Sommer, Wim Robberecht, Mika Saarela, Jerzy Kamienowski, Zbigniew Stelmasiak, Björn Tackenberg, Orell Mielke, A. Sabet, K. George, L. Roberts, R. Carne, S. Blum, R. Henderson, P. Van Damme, J. Demeestere, S. Larue, C. D'Amour, P. Kunc, and M. Valis
Restabilization treatment after intravenous immunoglobulin withdrawal in chronic inflammatory demyelinating polyneuropathy: Results from the pre-randomization phase of the Polyneuropathy And Treatment with Hizentra study, Orell Mielke, Vera Bril, David R. Cornblath, John Philip Lawo, Nan van Geloven, Hans Peter Hartung, Richard A. Lewis, Ingemar S.J. Merkies, Gen Sobue, Billie Durn, Amgad Shebl, Ivo N. van Schaik, A. Sabet, K. George, L. Roberts, R. Carne, S. Blum, R. Henderson, P. Van Damme, J. Demeestere, S. Larue, C. D'Amour, P. Kunc, M. Valis, J. Sussova, T. Kalous, R. Talab, M. Bednar, T. Toomsoo, I. Rubanovits, and K. Gross-Paju
Influence of Analytic Techniques on Comparing Dti-Derived Measurements in Early Stage Parkinson's Disease, Virendra R. Mishra, Karthik R. Sreenivasan, Xiaowei Zhuang, Zhengshi Yang, Dietmar Cordes, and Ryan R. Walsh
PATJ Low Frequency Variants Are Associated With Worse Ischemic Stroke Functional Outcome, Marina Mola-Caminal, Caty Carrera, Carolina Soriano-Tárraga, Eva Giralt-Steinhauer, Rosa M. Díaz-Navarro, Sílvia Tur, Carmen Jiménez, Aina Medina-Dols, Natàlia Cullell, Nuria P. Torres-Aguila, Elena Muiño, Ana Rodríguez-Campello, Angel Ois, Elisa Cuadrado-Godia, Rosa M. Vivanco-Hidalgo, Mar Hernandez-Guillamon, Montse Solé, Pilar Delgado, Alejandro Bustamante, Teresa García-Berrocoso, Maite Mendióroz, Mar Castellanos, Joaquín Serena, Joan Martí-Fàbregas, Tomás Segura, Gemma Serrano-Heras, Victor Obach, Marc Ribó, Carlos A. Molina, José Alvarez-Sabín, and Ernest Palomeras
Type 2 diabetes mellitus, brain atrophy, and cognitive decline, Chris Moran, Richard Beare, Wei Wang, Michele Callisaya, Velandai Srikanth, Michael Weiner, Paul Aisen, Ronald Petersen, Clifford R. Jack, William Jagust, John Q. Trojanowki, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, Andrew J. Saykin, John C. Morris, Enchi Liu, Tom Montine, Anthony Gamst, Ronald G. Thomas, Michael Donohue, Sarah Walter, Devon Gessert, Tamie Sather, Danielle Harvey, John Kornak, Anders Dale, Matthew Bernstein, Joel Felmlee, Nick Fox, and Paul Thompson
Is the association of weight disorders with perceived health status and life satisfaction independent of physical activity in children and adolescents? The CASPIAN-IV Study, Nazgol Motamed-Gorji, Ramin Heshmat, Mostafa Qorbani, Mohammad Esmaeil Motlagh, Akbar Soltani, Gita Shafiee, Hamid Asayesh, Gelayol Ardalan, Nassim Matin, Armita Mahdavi Gorabi, Mahla Alizadeh, and Roya Kelishadi
Long-term safety and efficacy of eculizumab in generalized myasthenia gravis., Srikanth Muppidi, Kimiaki Utsugisawa, Michael Benatar, Hiroyuki Murai, Richard J Barohn, Isabel Illa, Saiju Jacob, John Vissing, Ted M Burns, John T Kissel, Richard J Nowak, Henning Andersen, Carlos Casasnovas, Jan L de Bleecker, Tuan H Vu, Renato Mantegazza, Fanny L O'Brien, Jing Jing Wang, Kenji P Fujita, and James F Howard
Exosomes Secreted by the Cocultures of Normal and Oxygen-Glucose-Deprived Stem Cells Improve Post-stroke Outcome, Koteswara Rao Nalamolu, Ishwarya Venkatesh, Adithya Mohandass, Jeffrey D. Klopfenstein, David M. Pinson, David Z. Wang, Adinarayana Kunamneni, and Krishna Kumar Veeravalli
Unique Characteristics of Optical Coherence Tomography (OCT) Results and Visual Acuity Testing in Myelin Oligodendrocyte Glycoprotein (MOG) Antibody Positive Pediatric Patients, Ram N. Narayan, Morgan McCreary, Darrel Conger, Cynthia Wang, and Benjamin M. Greenberg
Motor Learning Deficits in Parkinson's Disease (PD) and Their Effect on Training Response in Gait and Balance: A Narrative Review, Markey Olson, Thurmon E. Lockhart, and Abraham N. Lieberman
Safety Tolerability Pharmacokinetics Pharmacodynamics and Exploratory Efficacy of the Novel Enzyme Replacement Therapy Avalglucosidase Alfa (Neogaa) in Treatment-naïve and Alglucosidase Alfa-Treated Patients With Late-Onset Pompe Disease: A Phase 1 Open-Label Multicenter Multinational Ascending Dose Study, Loren D.M. Pena, Richard J. Barohn, Barry J. Byrne, Claude Desnuelle, Ozlem Goker-Alpan, Shafeeq S. Ladha, Pascal Laforêt, Karl Eugen Mengel, Alan Pestronk, Jean Pouget, Benedikt Schoser, Volker Straub, Jaya Trivedi, Philip Van Damme, John Vissing, Peter Young, Katherine Kacena, Raheel Shafi, Beth L. Thurberg, and et al.
Clinical and functional outcomes after total laryngectomy and laryngopharyngectomy: Analysis by tumor subsite, salvage status, and extent of resection, Christopher J. Perdoni, Griffin D. Santarelli, Elliot Y. Koo, Daniel W. Karakla, and Matthew J. Bak
Predicting Progression to Mild Cognitive Impairment, Ronald C. Petersen, Emily S. Lundt, Terry M. Therneau, Stephen D. Weigand, David S. Knopman, Michelle M. Mielke, Rosebud O. Roberts, Val J. Lowe, Mary M. Machulda, Walter K. Kremers, Yonas E. Geda, and Clifford R. Jack
Lewy Body Dementia Association's Research Centers of Excellence Program: Inaugural Meeting Proceedings, Bethany Peterson, Melissa Armstrong, Douglas Galasko, James E. Galvin, Jennifer Goldman, David Irwin, Henry Paulson, Daniel Kaufer, James Leverenz, Angela Lunde, Ian G. McKeith, Andrew Siderowf, Angela Taylor, Katherine Amodeo, Matt Barrett, Kimiko Domoto-Reilly, John Duda, Stephen Gomperts, Holly A. Shill, and et al.
Brain MR radiomics to differentiate cognitive disorders, Sara Ranjbar, Stefanie N. Velgos, Amylou C. Dueck, Yonas E. Geda, and J. Ross Mitchell
Meeting Report: Report on the 9th International Congress of the Growth Hormone Research and IGF Societies, September 14-17, 2018, in Seattle, Washington, USA., Charles T Roberts and Kevin C J Yuen
Movement Disorders in Prionopathies: A Systematic Review, Federico Rodriguez-Porcel, Vinícius Boaratti Ciarlariello, Alok K. Dwivedi, Lilia Lovera, Gustavo Da Prat, Ricardo Lopez-Castellanos, Ritika Suri, Holly Laub, Ruth H. Walker, Orlando Barsottini, José Luiz Pedroso, and Alberto J. Espay
ALS Longitudinal Studies With Frequent Data Collection at Home: Study Design and Baseline Data, Seward B. Rutkove, Kristin Qi, Kerisa Shelton, Julie Liss, Visar Berisha, and Jeremy M. Shefner
Neurology and Therapy: Looking Back on 2018 and Forward to 2019, Marwan Sabbagh and Antonio Bertolotto
Peripheral Biomarkers for Alzheimer's Disease: Update and Progress, Marwan N. Sabbagh and Kaj Blennow
FDA position statement “Early Alzheimer's disease: Developing drugs for treatment, Guidance for Industry”, Marwan N. Sabbagh, Suzanne Hendrix, and John E. Harrison
Cingulate cortex in pre-MCI cognition, Nathalie Sambuchi, Yonas Endale Geda, and Bernard François Michel
Establishing Urinary Leukotriene E4 as a Diagnostic Biomarker for Chronic Rhinosinusitis with Comorbid Asthma and Atopy, Griffin D. Santarelli, Kent K. Lam, and Joseph K. Han
Lewy Body Pathology in Alzheimer's Disease: A Clinicopathological Prospective Study, Rodolfo Savica, Thomas G. Beach, Joseph G. Hentz, Marwan N. Sabbagh, Geidy E. Serrano, Lucia I. Sue, Brittany N. Dugger, Holly A. Shill, Erika Driver-Dunckley, John N. Caviness, Shyamal H. Mehta, Sandra A. Jacobson, Christine M. Belden, Kathryn J. Davis, Edward Zamrini, David R. Shprecher, and Charles H. Adler
Regional Amyloid-β Load and White Matter Abnormalities Contribute to Hypometabolism in Alzheimer’s Dementia, Lucas Porcello Schilling, Tharick A. Pascoal, Eduardo R. Zimmer, Sulantha Mathotaarachchi, Monica Shin, Carlos Roberto de Mello Rieder, Serge Gauthier, André Palmini, Pedro Rosa-Neto, Michael W. Weiner, Paul Aisen, Ronald Petersen, Ronald Clifford R. Jack, William Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, Andrew J. Saykin, John C. Morris, Leslie M. Shaw, Jeffrey Kaye, Joseph Quinn, Lisa Silbert, Betty Lind, Raina Carter, Sara Dolen, Lon S. Schneider, and Sonia Pawluczyk
Radiographic appearance of leptomeningeal disease in patients with EGFR-mutated non-small-cell lung carcinoma treated with tyrosine kinase inhibitors: a case series, Ugur Sener, Nassim Matin, Helena Yu, Andrew Lin, T Jonathan Yang, and Rachna Malani
A Phase III Trial of Tirasemtiv as a Potential Treatment for Amyotrophic Lateral Sclerosis, Jeremy M. Shefner, Merit E. Cudkowicz, Orla Hardiman, Bettina M. Cockroft, Jacqueline H. Lee, Fady I. Malik, Lisa Meng, Stacy A. Rudnicki, Andrew A. Wolff, and Jinsy A. Andrews
Challenges of targeting V600E mutations in adult primary brain tumor patients: a report of two cases, Matthew Smith-Cohn, Christian Davidson, Howard Colman, and Adam L. Cohen
A prospective study on gait dominant normal pressure hydrocephalus., Melissa Song, Abraham Lieberman, Terry D. Fife, Megan Nielsen, Sharon Hayden, Marwan Sabbagh, and Jiong Shi
Altered Functional Network Topology Correlates With Clinical Measures in Very Early-Stage Drug-Naïve Parkinson's Disease, Karthik Sreenivasan, Virendra Mishra, Christopher Bird, Xiaowei Zhuang, Zhengshi Yang, Dietmar Cordes, and Ryan R. Walsh
Impact of Zumba on Cognition and Quality of Life is Independent of APOE4 Carrier Status in Cognitively Unimpaired Older Women: A 6-Month Randomized Controlled Pilot Study, Cynthia M. Stonnington, Janina Krell-Roesch, Dona E.C. Locke, Joseph G. Hentz, Amylou C. Dueck, Yonas E. Geda, Pierre N. Tariot, and Richard J. Caselli
Emergency Preparedness of Secondary School Athletic Programs in Arizona, Tamara C. Valovich and Javier F. Cardenas
Predicting Short-term MCI-to-AD Progression Using Imaging, CSF, Genetic Factors, Cognitive Resilience, and Demographics, Yogatheesan Varatharajah, Vijay K. Ramanan, Ravishankar Iyer, Prashanthi Vemuri, Michael W. Weiner, Paul Aisen, Ronald Petersen, Clifford R. Jack, Andrew J. Saykin, William Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, John Morris, Leslie M. Shaw, Zaven Khachaturian, Greg Sorensen, Maria Carrillo, Lew Kuller, Marc Raichle, Steven Paul, Peter Davies, Howard Fillit, Franz Hefti, David Holtzman, M. Marcel Mesulam, William Potter, and Peter Snyder
Informant-based hearing difficulties and the risk for mild cognitive impairment and dementia, Maria Vassilaki, Jeremiah A. Aakre, David S. Knopman, Walter K. Kremers, Michelle M. Mielke, Yonas E. Geda, Mary M. Machulda, Razan Al Fakir, Chaitanya Undavalli, Rosebud O. Roberts, and Ronald C. Petersen