ε4 is associated with younger age at ischemic stroke onset but not with stroke outcome

Cecilia Lagging, From the Department of Laboratory Medicine (C.L., T.M.S., A.P., C.J.), Institute of Biomedicine, the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Clinical Genetics and Genomics (C.L., A.P., C.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Bioinformatics Core Facility (E.L.), University of Gothenburg, Sweden; Department of Clinical Sciences Lund (M.S., A.L.), Neurology, Lund University, Sweden; Department of Neurology and Rehabilitation Medicine (M.S.), Neurology, Skåne University Hospital, Malmö, Sweden; Department of Neurology (J.W.C.), Baltimore VA Medical Center and University of Maryland School of Medicine, Baltimore, MD; Department of Neurology (K.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Clinical Neuroscience (K.J.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy University of Gothenburg, Sweden; Neurosciences (R.L.), Experimental Neurology, KU Leuven-University of Leuven; VIB-Center for Brain & Disease Research (R.L.); Department of Neurology (R.L.), University Hospitals Leuven, Belgium; Department of Neurology (C.-L.P.), Washington University School of Medicine in St. Louis; J. Philip Kistler Stroke Research Center (N.S.R.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston; Stroke Division (V.T.), Florey Institute of Neuroscience and Mental Health, University of Melbourne, Heidelberg, Victoria, Australia; Department of Neurology (V.T.), Austin Health, Heidelberg, Victoria, Australia; Department of Neurology and Rehabilitation (D.W.), University of Cincinnati College of Medicine, OH; Faculty of Health (J.M.M.), University of Technology Sydney, Sydney, Australia; Hunter Medical Research Centre (J.M.M.), Newcastle, Australia; and Department of Neurology and Rehabilitation Medicine (A.L.), Neurology, Skåne University Hospital, Lund, Sweden. cecilia.lagging@gu.se.
Erik Lorentzen, From the Department of Laboratory Medicine (C.L., T.M.S., A.P., C.J.), Institute of Biomedicine, the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Clinical Genetics and Genomics (C.L., A.P., C.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Bioinformatics Core Facility (E.L.), University of Gothenburg, Sweden; Department of Clinical Sciences Lund (M.S., A.L.), Neurology, Lund University, Sweden; Department of Neurology and Rehabilitation Medicine (M.S.), Neurology, Skåne University Hospital, Malmö, Sweden; Department of Neurology (J.W.C.), Baltimore VA Medical Center and University of Maryland School of Medicine, Baltimore, MD; Department of Neurology (K.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Clinical Neuroscience (K.J.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy University of Gothenburg, Sweden; Neurosciences (R.L.), Experimental Neurology, KU Leuven-University of Leuven; VIB-Center for Brain & Disease Research (R.L.); Department of Neurology (R.L.), University Hospitals Leuven, Belgium; Department of Neurology (C.-L.P.), Washington University School of Medicine in St. Louis; J. Philip Kistler Stroke Research Center (N.S.R.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston; Stroke Division (V.T.), Florey Institute of Neuroscience and Mental Health, University of Melbourne, Heidelberg, Victoria, Australia; Department of Neurology (V.T.), Austin Health, Heidelberg, Victoria, Australia; Department of Neurology and Rehabilitation (D.W.), University of Cincinnati College of Medicine, OH; Faculty of Health (J.M.M.), University of Technology Sydney, Sydney, Australia; Hunter Medical Research Centre (J.M.M.), Newcastle, Australia; and Department of Neurology and Rehabilitation Medicine (A.L.), Neurology, Skåne University Hospital, Lund, Sweden.
Tara M. Stanne, From the Department of Laboratory Medicine (C.L., T.M.S., A.P., C.J.), Institute of Biomedicine, the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Clinical Genetics and Genomics (C.L., A.P., C.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Bioinformatics Core Facility (E.L.), University of Gothenburg, Sweden; Department of Clinical Sciences Lund (M.S., A.L.), Neurology, Lund University, Sweden; Department of Neurology and Rehabilitation Medicine (M.S.), Neurology, Skåne University Hospital, Malmö, Sweden; Department of Neurology (J.W.C.), Baltimore VA Medical Center and University of Maryland School of Medicine, Baltimore, MD; Department of Neurology (K.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Clinical Neuroscience (K.J.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy University of Gothenburg, Sweden; Neurosciences (R.L.), Experimental Neurology, KU Leuven-University of Leuven; VIB-Center for Brain & Disease Research (R.L.); Department of Neurology (R.L.), University Hospitals Leuven, Belgium; Department of Neurology (C.-L.P.), Washington University School of Medicine in St. Louis; J. Philip Kistler Stroke Research Center (N.S.R.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston; Stroke Division (V.T.), Florey Institute of Neuroscience and Mental Health, University of Melbourne, Heidelberg, Victoria, Australia; Department of Neurology (V.T.), Austin Health, Heidelberg, Victoria, Australia; Department of Neurology and Rehabilitation (D.W.), University of Cincinnati College of Medicine, OH; Faculty of Health (J.M.M.), University of Technology Sydney, Sydney, Australia; Hunter Medical Research Centre (J.M.M.), Newcastle, Australia; and Department of Neurology and Rehabilitation Medicine (A.L.), Neurology, Skåne University Hospital, Lund, Sweden.
Annie Pedersen, From the Department of Laboratory Medicine (C.L., T.M.S., A.P., C.J.), Institute of Biomedicine, the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Clinical Genetics and Genomics (C.L., A.P., C.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Bioinformatics Core Facility (E.L.), University of Gothenburg, Sweden; Department of Clinical Sciences Lund (M.S., A.L.), Neurology, Lund University, Sweden; Department of Neurology and Rehabilitation Medicine (M.S.), Neurology, Skåne University Hospital, Malmö, Sweden; Department of Neurology (J.W.C.), Baltimore VA Medical Center and University of Maryland School of Medicine, Baltimore, MD; Department of Neurology (K.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Clinical Neuroscience (K.J.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy University of Gothenburg, Sweden; Neurosciences (R.L.), Experimental Neurology, KU Leuven-University of Leuven; VIB-Center for Brain & Disease Research (R.L.); Department of Neurology (R.L.), University Hospitals Leuven, Belgium; Department of Neurology (C.-L.P.), Washington University School of Medicine in St. Louis; J. Philip Kistler Stroke Research Center (N.S.R.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston; Stroke Division (V.T.), Florey Institute of Neuroscience and Mental Health, University of Melbourne, Heidelberg, Victoria, Australia; Department of Neurology (V.T.), Austin Health, Heidelberg, Victoria, Australia; Department of Neurology and Rehabilitation (D.W.), University of Cincinnati College of Medicine, OH; Faculty of Health (J.M.M.), University of Technology Sydney, Sydney, Australia; Hunter Medical Research Centre (J.M.M.), Newcastle, Australia; and Department of Neurology and Rehabilitation Medicine (A.L.), Neurology, Skåne University Hospital, Lund, Sweden.
Martin Söderholm, From the Department of Laboratory Medicine (C.L., T.M.S., A.P., C.J.), Institute of Biomedicine, the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Clinical Genetics and Genomics (C.L., A.P., C.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Bioinformatics Core Facility (E.L.), University of Gothenburg, Sweden; Department of Clinical Sciences Lund (M.S., A.L.), Neurology, Lund University, Sweden; Department of Neurology and Rehabilitation Medicine (M.S.), Neurology, Skåne University Hospital, Malmö, Sweden; Department of Neurology (J.W.C.), Baltimore VA Medical Center and University of Maryland School of Medicine, Baltimore, MD; Department of Neurology (K.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Clinical Neuroscience (K.J.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy University of Gothenburg, Sweden; Neurosciences (R.L.), Experimental Neurology, KU Leuven-University of Leuven; VIB-Center for Brain & Disease Research (R.L.); Department of Neurology (R.L.), University Hospitals Leuven, Belgium; Department of Neurology (C.-L.P.), Washington University School of Medicine in St. Louis; J. Philip Kistler Stroke Research Center (N.S.R.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston; Stroke Division (V.T.), Florey Institute of Neuroscience and Mental Health, University of Melbourne, Heidelberg, Victoria, Australia; Department of Neurology (V.T.), Austin Health, Heidelberg, Victoria, Australia; Department of Neurology and Rehabilitation (D.W.), University of Cincinnati College of Medicine, OH; Faculty of Health (J.M.M.), University of Technology Sydney, Sydney, Australia; Hunter Medical Research Centre (J.M.M.), Newcastle, Australia; and Department of Neurology and Rehabilitation Medicine (A.L.), Neurology, Skåne University Hospital, Lund, Sweden.
John W. Cole, From the Department of Laboratory Medicine (C.L., T.M.S., A.P., C.J.), Institute of Biomedicine, the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Clinical Genetics and Genomics (C.L., A.P., C.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Bioinformatics Core Facility (E.L.), University of Gothenburg, Sweden; Department of Clinical Sciences Lund (M.S., A.L.), Neurology, Lund University, Sweden; Department of Neurology and Rehabilitation Medicine (M.S.), Neurology, Skåne University Hospital, Malmö, Sweden; Department of Neurology (J.W.C.), Baltimore VA Medical Center and University of Maryland School of Medicine, Baltimore, MD; Department of Neurology (K.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Clinical Neuroscience (K.J.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy University of Gothenburg, Sweden; Neurosciences (R.L.), Experimental Neurology, KU Leuven-University of Leuven; VIB-Center for Brain & Disease Research (R.L.); Department of Neurology (R.L.), University Hospitals Leuven, Belgium; Department of Neurology (C.-L.P.), Washington University School of Medicine in St. Louis; J. Philip Kistler Stroke Research Center (N.S.R.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston; Stroke Division (V.T.), Florey Institute of Neuroscience and Mental Health, University of Melbourne, Heidelberg, Victoria, Australia; Department of Neurology (V.T.), Austin Health, Heidelberg, Victoria, Australia; Department of Neurology and Rehabilitation (D.W.), University of Cincinnati College of Medicine, OH; Faculty of Health (J.M.M.), University of Technology Sydney, Sydney, Australia; Hunter Medical Research Centre (J.M.M.), Newcastle, Australia; and Department of Neurology and Rehabilitation Medicine (A.L.), Neurology, Skåne University Hospital, Lund, Sweden.
Katarina Jood, From the Department of Laboratory Medicine (C.L., T.M.S., A.P., C.J.), Institute of Biomedicine, the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Clinical Genetics and Genomics (C.L., A.P., C.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Bioinformatics Core Facility (E.L.), University of Gothenburg, Sweden; Department of Clinical Sciences Lund (M.S., A.L.), Neurology, Lund University, Sweden; Department of Neurology and Rehabilitation Medicine (M.S.), Neurology, Skåne University Hospital, Malmö, Sweden; Department of Neurology (J.W.C.), Baltimore VA Medical Center and University of Maryland School of Medicine, Baltimore, MD; Department of Neurology (K.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Clinical Neuroscience (K.J.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy University of Gothenburg, Sweden; Neurosciences (R.L.), Experimental Neurology, KU Leuven-University of Leuven; VIB-Center for Brain & Disease Research (R.L.); Department of Neurology (R.L.), University Hospitals Leuven, Belgium; Department of Neurology (C.-L.P.), Washington University School of Medicine in St. Louis; J. Philip Kistler Stroke Research Center (N.S.R.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston; Stroke Division (V.T.), Florey Institute of Neuroscience and Mental Health, University of Melbourne, Heidelberg, Victoria, Australia; Department of Neurology (V.T.), Austin Health, Heidelberg, Victoria, Australia; Department of Neurology and Rehabilitation (D.W.), University of Cincinnati College of Medicine, OH; Faculty of Health (J.M.M.), University of Technology Sydney, Sydney, Australia; Hunter Medical Research Centre (J.M.M.), Newcastle, Australia; and Department of Neurology and Rehabilitation Medicine (A.L.), Neurology, Skåne University Hospital, Lund, Sweden.
Robin Lemmens, From the Department of Laboratory Medicine (C.L., T.M.S., A.P., C.J.), Institute of Biomedicine, the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Clinical Genetics and Genomics (C.L., A.P., C.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Bioinformatics Core Facility (E.L.), University of Gothenburg, Sweden; Department of Clinical Sciences Lund (M.S., A.L.), Neurology, Lund University, Sweden; Department of Neurology and Rehabilitation Medicine (M.S.), Neurology, Skåne University Hospital, Malmö, Sweden; Department of Neurology (J.W.C.), Baltimore VA Medical Center and University of Maryland School of Medicine, Baltimore, MD; Department of Neurology (K.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Clinical Neuroscience (K.J.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy University of Gothenburg, Sweden; Neurosciences (R.L.), Experimental Neurology, KU Leuven-University of Leuven; VIB-Center for Brain & Disease Research (R.L.); Department of Neurology (R.L.), University Hospitals Leuven, Belgium; Department of Neurology (C.-L.P.), Washington University School of Medicine in St. Louis; J. Philip Kistler Stroke Research Center (N.S.R.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston; Stroke Division (V.T.), Florey Institute of Neuroscience and Mental Health, University of Melbourne, Heidelberg, Victoria, Australia; Department of Neurology (V.T.), Austin Health, Heidelberg, Victoria, Australia; Department of Neurology and Rehabilitation (D.W.), University of Cincinnati College of Medicine, OH; Faculty of Health (J.M.M.), University of Technology Sydney, Sydney, Australia; Hunter Medical Research Centre (J.M.M.), Newcastle, Australia; and Department of Neurology and Rehabilitation Medicine (A.L.), Neurology, Skåne University Hospital, Lund, Sweden.
Chia-Ling Phuah, From the Department of Laboratory Medicine (C.L., T.M.S., A.P., C.J.), Institute of Biomedicine, the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Clinical Genetics and Genomics (C.L., A.P., C.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Bioinformatics Core Facility (E.L.), University of Gothenburg, Sweden; Department of Clinical Sciences Lund (M.S., A.L.), Neurology, Lund University, Sweden; Department of Neurology and Rehabilitation Medicine (M.S.), Neurology, Skåne University Hospital, Malmö, Sweden; Department of Neurology (J.W.C.), Baltimore VA Medical Center and University of Maryland School of Medicine, Baltimore, MD; Department of Neurology (K.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Clinical Neuroscience (K.J.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy University of Gothenburg, Sweden; Neurosciences (R.L.), Experimental Neurology, KU Leuven-University of Leuven; VIB-Center for Brain & Disease Research (R.L.); Department of Neurology (R.L.), University Hospitals Leuven, Belgium; Department of Neurology (C.-L.P.), Washington University School of Medicine in St. Louis; J. Philip Kistler Stroke Research Center (N.S.R.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston; Stroke Division (V.T.), Florey Institute of Neuroscience and Mental Health, University of Melbourne, Heidelberg, Victoria, Australia; Department of Neurology (V.T.), Austin Health, Heidelberg, Victoria, Australia; Department of Neurology and Rehabilitation (D.W.), University of Cincinnati College of Medicine, OH; Faculty of Health (J.M.M.), University of Technology Sydney, Sydney, Australia; Hunter Medical Research Centre (J.M.M.), Newcastle, Australia; and Department of Neurology and Rehabilitation Medicine (A.L.), Neurology, Skåne University Hospital, Lund, Sweden.
Natalia S. Rost, From the Department of Laboratory Medicine (C.L., T.M.S., A.P., C.J.), Institute of Biomedicine, the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Clinical Genetics and Genomics (C.L., A.P., C.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Bioinformatics Core Facility (E.L.), University of Gothenburg, Sweden; Department of Clinical Sciences Lund (M.S., A.L.), Neurology, Lund University, Sweden; Department of Neurology and Rehabilitation Medicine (M.S.), Neurology, Skåne University Hospital, Malmö, Sweden; Department of Neurology (J.W.C.), Baltimore VA Medical Center and University of Maryland School of Medicine, Baltimore, MD; Department of Neurology (K.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Clinical Neuroscience (K.J.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy University of Gothenburg, Sweden; Neurosciences (R.L.), Experimental Neurology, KU Leuven-University of Leuven; VIB-Center for Brain & Disease Research (R.L.); Department of Neurology (R.L.), University Hospitals Leuven, Belgium; Department of Neurology (C.-L.P.), Washington University School of Medicine in St. Louis; J. Philip Kistler Stroke Research Center (N.S.R.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston; Stroke Division (V.T.), Florey Institute of Neuroscience and Mental Health, University of Melbourne, Heidelberg, Victoria, Australia; Department of Neurology (V.T.), Austin Health, Heidelberg, Victoria, Australia; Department of Neurology and Rehabilitation (D.W.), University of Cincinnati College of Medicine, OH; Faculty of Health (J.M.M.), University of Technology Sydney, Sydney, Australia; Hunter Medical Research Centre (J.M.M.), Newcastle, Australia; and Department of Neurology and Rehabilitation Medicine (A.L.), Neurology, Skåne University Hospital, Lund, Sweden.
Vincent Thijs, From the Department of Laboratory Medicine (C.L., T.M.S., A.P., C.J.), Institute of Biomedicine, the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Clinical Genetics and Genomics (C.L., A.P., C.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Bioinformatics Core Facility (E.L.), University of Gothenburg, Sweden; Department of Clinical Sciences Lund (M.S., A.L.), Neurology, Lund University, Sweden; Department of Neurology and Rehabilitation Medicine (M.S.), Neurology, Skåne University Hospital, Malmö, Sweden; Department of Neurology (J.W.C.), Baltimore VA Medical Center and University of Maryland School of Medicine, Baltimore, MD; Department of Neurology (K.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Clinical Neuroscience (K.J.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy University of Gothenburg, Sweden; Neurosciences (R.L.), Experimental Neurology, KU Leuven-University of Leuven; VIB-Center for Brain & Disease Research (R.L.); Department of Neurology (R.L.), University Hospitals Leuven, Belgium; Department of Neurology (C.-L.P.), Washington University School of Medicine in St. Louis; J. Philip Kistler Stroke Research Center (N.S.R.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston; Stroke Division (V.T.), Florey Institute of Neuroscience and Mental Health, University of Melbourne, Heidelberg, Victoria, Australia; Department of Neurology (V.T.), Austin Health, Heidelberg, Victoria, Australia; Department of Neurology and Rehabilitation (D.W.), University of Cincinnati College of Medicine, OH; Faculty of Health (J.M.M.), University of Technology Sydney, Sydney, Australia; Hunter Medical Research Centre (J.M.M.), Newcastle, Australia; and Department of Neurology and Rehabilitation Medicine (A.L.), Neurology, Skåne University Hospital, Lund, Sweden.
Daniel Woo, From the Department of Laboratory Medicine (C.L., T.M.S., A.P., C.J.), Institute of Biomedicine, the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Clinical Genetics and Genomics (C.L., A.P., C.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Bioinformatics Core Facility (E.L.), University of Gothenburg, Sweden; Department of Clinical Sciences Lund (M.S., A.L.), Neurology, Lund University, Sweden; Department of Neurology and Rehabilitation Medicine (M.S.), Neurology, Skåne University Hospital, Malmö, Sweden; Department of Neurology (J.W.C.), Baltimore VA Medical Center and University of Maryland School of Medicine, Baltimore, MD; Department of Neurology (K.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Clinical Neuroscience (K.J.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy University of Gothenburg, Sweden; Neurosciences (R.L.), Experimental Neurology, KU Leuven-University of Leuven; VIB-Center for Brain & Disease Research (R.L.); Department of Neurology (R.L.), University Hospitals Leuven, Belgium; Department of Neurology (C.-L.P.), Washington University School of Medicine in St. Louis; J. Philip Kistler Stroke Research Center (N.S.R.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston; Stroke Division (V.T.), Florey Institute of Neuroscience and Mental Health, University of Melbourne, Heidelberg, Victoria, Australia; Department of Neurology (V.T.), Austin Health, Heidelberg, Victoria, Australia; Department of Neurology and Rehabilitation (D.W.), University of Cincinnati College of Medicine, OH; Faculty of Health (J.M.M.), University of Technology Sydney, Sydney, Australia; Hunter Medical Research Centre (J.M.M.), Newcastle, Australia; and Department of Neurology and Rehabilitation Medicine (A.L.), Neurology, Skåne University Hospital, Lund, Sweden.
Jane M. Maguire, From the Department of Laboratory Medicine (C.L., T.M.S., A.P., C.J.), Institute of Biomedicine, the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Clinical Genetics and Genomics (C.L., A.P., C.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Bioinformatics Core Facility (E.L.), University of Gothenburg, Sweden; Department of Clinical Sciences Lund (M.S., A.L.), Neurology, Lund University, Sweden; Department of Neurology and Rehabilitation Medicine (M.S.), Neurology, Skåne University Hospital, Malmö, Sweden; Department of Neurology (J.W.C.), Baltimore VA Medical Center and University of Maryland School of Medicine, Baltimore, MD; Department of Neurology (K.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Clinical Neuroscience (K.J.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy University of Gothenburg, Sweden; Neurosciences (R.L.), Experimental Neurology, KU Leuven-University of Leuven; VIB-Center for Brain & Disease Research (R.L.); Department of Neurology (R.L.), University Hospitals Leuven, Belgium; Department of Neurology (C.-L.P.), Washington University School of Medicine in St. Louis; J. Philip Kistler Stroke Research Center (N.S.R.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston; Stroke Division (V.T.), Florey Institute of Neuroscience and Mental Health, University of Melbourne, Heidelberg, Victoria, Australia; Department of Neurology (V.T.), Austin Health, Heidelberg, Victoria, Australia; Department of Neurology and Rehabilitation (D.W.), University of Cincinnati College of Medicine, OH; Faculty of Health (J.M.M.), University of Technology Sydney, Sydney, Australia; Hunter Medical Research Centre (J.M.M.), Newcastle, Australia; and Department of Neurology and Rehabilitation Medicine (A.L.), Neurology, Skåne University Hospital, Lund, Sweden.
Arne Lindgren, From the Department of Laboratory Medicine (C.L., T.M.S., A.P., C.J.), Institute of Biomedicine, the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Clinical Genetics and Genomics (C.L., A.P., C.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Bioinformatics Core Facility (E.L.), University of Gothenburg, Sweden; Department of Clinical Sciences Lund (M.S., A.L.), Neurology, Lund University, Sweden; Department of Neurology and Rehabilitation Medicine (M.S.), Neurology, Skåne University Hospital, Malmö, Sweden; Department of Neurology (J.W.C.), Baltimore VA Medical Center and University of Maryland School of Medicine, Baltimore, MD; Department of Neurology (K.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Clinical Neuroscience (K.J.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy University of Gothenburg, Sweden; Neurosciences (R.L.), Experimental Neurology, KU Leuven-University of Leuven; VIB-Center for Brain & Disease Research (R.L.); Department of Neurology (R.L.), University Hospitals Leuven, Belgium; Department of Neurology (C.-L.P.), Washington University School of Medicine in St. Louis; J. Philip Kistler Stroke Research Center (N.S.R.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston; Stroke Division (V.T.), Florey Institute of Neuroscience and Mental Health, University of Melbourne, Heidelberg, Victoria, Australia; Department of Neurology (V.T.), Austin Health, Heidelberg, Victoria, Australia; Department of Neurology and Rehabilitation (D.W.), University of Cincinnati College of Medicine, OH; Faculty of Health (J.M.M.), University of Technology Sydney, Sydney, Australia; Hunter Medical Research Centre (J.M.M.), Newcastle, Australia; and Department of Neurology and Rehabilitation Medicine (A.L.), Neurology, Skåne University Hospital, Lund, Sweden.
Christina Jern, From the Department of Laboratory Medicine (C.L., T.M.S., A.P., C.J.), Institute of Biomedicine, the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Clinical Genetics and Genomics (C.L., A.P., C.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Bioinformatics Core Facility (E.L.), University of Gothenburg, Sweden; Department of Clinical Sciences Lund (M.S., A.L.), Neurology, Lund University, Sweden; Department of Neurology and Rehabilitation Medicine (M.S.), Neurology, Skåne University Hospital, Malmö, Sweden; Department of Neurology (J.W.C.), Baltimore VA Medical Center and University of Maryland School of Medicine, Baltimore, MD; Department of Neurology (K.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Clinical Neuroscience (K.J.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy University of Gothenburg, Sweden; Neurosciences (R.L.), Experimental Neurology, KU Leuven-University of Leuven; VIB-Center for Brain & Disease Research (R.L.); Department of Neurology (R.L.), University Hospitals Leuven, Belgium; Department of Neurology (C.-L.P.), Washington University School of Medicine in St. Louis; J. Philip Kistler Stroke Research Center (N.S.R.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston; Stroke Division (V.T.), Florey Institute of Neuroscience and Mental Health, University of Melbourne, Heidelberg, Victoria, Australia; Department of Neurology (V.T.), Austin Health, Heidelberg, Victoria, Australia; Department of Neurology and Rehabilitation (D.W.), University of Cincinnati College of Medicine, OH; Faculty of Health (J.M.M.), University of Technology Sydney, Sydney, Australia; Hunter Medical Research Centre (J.M.M.), Newcastle, Australia; and Department of Neurology and Rehabilitation Medicine (A.L.), Neurology, Skåne University Hospital, Lund, Sweden.

Document Type

Article

Medical Subject Headings

Age of Onset; Alleles; Apolipoprotein E2 (genetics); Apolipoprotein E3 (genetics); Apolipoprotein E4 (genetics); Brain Ischemia (epidemiology, genetics, physiopathology); Genome-Wide Association Study; Genotype; Humans; Polymorphism, Single Nucleotide; Prognosis; Severity of Illness Index; Sex Factors; Stroke (epidemiology, genetics, physiopathology)

Publication Date

11-5-2019

Publication Title

Neurology

E-ISSN

1526-632X

Volume

93

Issue

19

First Page

849

Last Page

853

PubMed ID

31619479

Digital Object Identifier (DOI)

10.1212/WNL.0000000000008459

Link to Full Text

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