Serial Optic Nerve Sheath Diameter via Radiographic Imaging: Correlation With ICP and Outcomes

Authors

Diane McLaughlin, Department of Critical Care (DM), Mayo Clinic, Jacksonville, FL; Department of Neurosurgery MetroHealth (LA), Cleveland; Ohio State University (JG); and The Helene Fuld Health Trust National Institute for Evidence-Based Practice in Nursing and Healthcare (MM), Ohio State University, Columbus.
Lisa Anderson, Department of Critical Care (DM), Mayo Clinic, Jacksonville, FL; Department of Neurosurgery MetroHealth (LA), Cleveland; Ohio State University (JG); and The Helene Fuld Health Trust National Institute for Evidence-Based Practice in Nursing and Healthcare (MM), Ohio State University, Columbus.
Jinhong Guo, Department of Critical Care (DM), Mayo Clinic, Jacksonville, FL; Department of Neurosurgery MetroHealth (LA), Cleveland; Ohio State University (JG); and The Helene Fuld Health Trust National Institute for Evidence-Based Practice in Nursing and Healthcare (MM), Ohio State University, Columbus.
Molly McNett, Department of Critical Care (DM), Mayo Clinic, Jacksonville, FL; Department of Neurosurgery MetroHealth (LA), Cleveland; Ohio State University (JG); and The Helene Fuld Health Trust National Institute for Evidence-Based Practice in Nursing and Healthcare (MM), Ohio State University, Columbus.

Document Type

Article

Abstract

OBJECTIVE: Evaluation of optic nerve sheath diameter (ONSD) is a suggested correlation of intracranial pressure (ICP) and potential predictor of outcome after neurologic injury. Studies have evaluated sonographic measurement of ONSD; however, clinical limitations to this approach persist. Evaluation of ONSD measurements via routine brain CT imaging is less studied but offers potential for detection of increased ICP in the absence of invasive monitoring. Previous studies have used cross-sectional approaches to ONSD measurements via CT scan among patients with traumatic brain injury (TBI). No studies have evaluated serial correlations between CT ONSD measurements and ICP throughout hospitalization and across diagnosis types. The objective of this study was to investigate correlations between ONSD via serial CT imaging, ICP, and outcome at discharge among patients with neurologic injury. METHODS: This is a retrospective cohort study of all adult patients admitted during a 12-month period with acute neurologic injury requiring ICP monitoring and critical care admission. RESULTS: N = 48. There was a strong, positive correlation between right/left ONSD across time points (r = 0.7-9, p < 0.001), suggesting a consistent bilateral response. Correlations were strongest between initial inpatient CT scan ONSD readings and ICP (r = 0.5, p < 0.05), but decreased over time. Patients with increased ICP across all diagnosis types experienced higher ONSD values on presentation to the emergency department (ED) and throughout hospitalization (range 5.7-6.4 mm, p < 0.05). CONCLUSIONS: Findings contribute to the utility of CT ONSD measurements as a potential indicator of increased ICP. Measurement of ONSD during serial CT brain imaging may inform clinical decisions regarding need for more invasive monitoring after neurologic injury.

Publication Date

10-1-2021

Publication Title

Neurology. Clinical practice

ISSN

2163-0402

Volume

11

Issue

5

First Page

e620

Last Page

e626

PubMed ID

34840875

Digital Object Identifier (DOI)

10.1212/CPJ.0000000000001038

Recommended Citation

McLaughlin, Diane; Anderson, Lisa; Guo, Jinhong; and McNett, Molly, "Serial Optic Nerve Sheath Diameter via Radiographic Imaging: Correlation With ICP and Outcomes" (2021). Neurology. 1959.
https://scholar.barrowneuro.org/neurology/1959