Clinical assessment of cognitive decline in adults with down syndrome
Document Type
Article
Abstract
Down syndrome is an intellectual disability requiring periodic monitoring of cognition given the near universal presence of Alzheimer’s Disease related neuropathology and high rates of dementia in middle adulthood. We review current approaches to detecting decline in this population, including informant-based measures, dementia screening tools, and neuroimaging techniques. The challenges for detecting decline in this group are discussed, including the need to take into account premorbid cognitive function as well as medical comorbidity.
Publication Date
1-1-2016
Publication Title
Current Alzheimer Research
ISSN
15672050
E-ISSN
18755828
Volume
13
Issue
1
First Page
30
Last Page
34
PubMed ID
26391049
Digital Object Identifier (DOI)
10.2174/1567205012666150921095724
Recommended Citation
Sabbagh, Marwan and Edgin, Jamie, "Clinical assessment of cognitive decline in adults with down syndrome" (2016). Neurology. 807.
https://scholar.barrowneuro.org/neurology/807