Submissions from 2019


ALS Drug Development Guidances and Trial Guidelines: Consensus and Opportunities for Alignment, Jinsy A. Andrews, Lucie I. Bruijn, and Jeremy M. Shefner

Does Informant-Based Reporting of Cognitive Symptoms Predict Amyloid Positivity on Positron Emission Tomography?, Hannah E. Brunet, Justin B. Miller, Jiong Shi, Briana Chung, Bryce Taylor Munter, and Marwan Noel Sabbagh

Sirtuin 3 Promotes Microglia Migration by Upregulating Cx3Cr1, Runjing Cao, Shiping Li, Junxiang Yin, Li Guo, and Jiong Shi

Clinical Outcomes Following Awake and Asleep Deep Brain Stimulation for Parkinson Disease, Tsinsue Chen, Zaman Mirzadeh, Kristina M. Chapple, Margaret Lambert, Holly A. Shill, Guillermo Moguel-Cobos, Alexander I. Tröster, Rohit Dhall, and Francisco A. Ponce

Brain Lewy-Type Synucleinopathy Density is Associated With a Lower Prevalence of Atherosclerotic Cardiovascular Disease Risk Factors in Patients With Parkinson's Disease, Erika D. Driver-Dunckley, Nan Zhang, Charles H. Adler, Geidy E. Serrano, Lucia I. Sue, Holly A. Shill, Shyamal H. Mehta, Christine M. Belden, Edward Y. Zamrini, Kathryn Davis, and Thomas G. Beach

Tau Immunoreactivity in Peripheral Tissues of Human Aging and Select Tauopathies, Brittany N. Dugger, Brittany R. Hoffman, Alex Scroggins, Geidy E. Serrano, Charles H. Adler, Holly A. Shill, Christine M. Belden, Marwan N. Sabbagh, John N. Caviness, Erika Driver Dunckley, and Thomas G. Beach

The Current State of Molecular Testing in the Treatment of Patients With Solid Tumors 2019, Wafik S. El-Deiry, Richard M. Goldberg, Heinz Josef Lenz, Anthony F. Shields, Geoffrey T. Gibney, Antoinette R. Tan, Jubilee Brown, Burton Eisenberg, Elisabeth I. Heath, Surasak Phuphanich, Edward Kim, Andrew J. Brenner, and John L. Marshall

Regional Neuropathology Distribution and Verbal Fluency Impairments in Parkinson's Disease, Rasheda El-Nazer, Charles H. Adler, Thomas G. Beach, Christine M. Belden, Jonathan Artz, Holly A. Shill, Erika Driver-Dunckley, Shyamal H. Mehta, Marwan N. Sabbagh, Geidy E. Serrano, Lucia I. Sue, Edward Zamrini, and Jared F. Benge

Present Algorithms and Future Treatments for Alzheimer's Disease, George T. Grossberg, Gary Tong, Anna D. Burke, and Pierre N. Tariot

Prevalence of Dyskinesia and Off by 30-Minute Intervals Through the Day and Assessment of Daily Episodes of Dyskinesia and Off: Novel Analyses of Diary Data From Gocovri Pivotal Trials, Robert A. Hauser, Daniel E. Kremens, Lawrence W. Elmer, David L. Kreitzman, Ryan R. Walsh, Reed Johnson, Robert Howard, Jack T. Nguyen, and Rajiv Patni


Cerebellar Syndrome in a Man Treated With Natalizumab: From the National Multiple Sclerosis Society Case Conference Proceedings, David A. Lapides, Prem P. Batchala, Joseph H. Donahue, Robert P. Lisak, Ethan I. Meltzer, Ram N. Narayan, Avi Nath, Teresa C. Frohman, Kathleen Costello, Myla D. Goldman, Scott S. Zamvil, and Elliot M. Frohman


Nicotine Bitartrate Reduces Falls and Freezing of Gait in Parkinson Disease: A Reanalysis, Abraham N. Lieberman, Thurmon E. Lockhart, Markey C. Olson, Victoria A. Hussain, Christopher W. Frames, Arshia Sadreddin, Margaret McCauley, and Elizabeth Ludington

Sirtuin 3 Mediates Tau Deacetylation, Shiping Li, Junxiang Yin, Megan Nielsen, Thomas G. Beach, Li Guo, and Jiong Shi

Faster Cognitive Decline in Dementia Due to Alzheimer Disease With Clinically Undiagnosed Lewy Body Disease, Michael Malek-Ahmadi, Thomas G. Beach, Edward Zamrini, Charles H. Adler, Marwan N. Sabbagh, Holly A. Shill, Sandra A. Jacobson, Christine M. Belden, Richard J. Caselli, Brian K. Woodruff, Steven Z. Rapscak, Geoffrey L. Ahern, Jiong Shi, John N. Caviness, Erika Driver-Dunckley, Shyamal H. Mehta, David R. Shprecher, Bryan M. Spann, Pierre Tariot, and et al.


Influence of Analytic Techniques on Comparing Dti-Derived Measurements in Early Stage Parkinson's Disease, Virendra R. Mishra, Karthik R. Sreenivasan, Xiaowei Zhuang, Zhengshi Yang, Dietmar Cordes, and Ryan R. Walsh

Unique Characteristics of Optical Coherence Tomography (OCT) Results and Visual Acuity Testing in Myelin Oligodendrocyte Glycoprotein (MOG) Antibody Positive Pediatric Patients, Ram N. Narayan, Morgan McCreary, Darrel Conger, Cynthia Wang, and Benjamin M. Greenberg


Motor Learning Deficits in Parkinson's Disease (PD) and Their Effect on Training Response in Gait and Balance: A Narrative Review, Markey Olson, Thurmon E. Lockhart, and Abraham N. Lieberman

Safety Tolerability Pharmacokinetics Pharmacodynamics and Exploratory Efficacy of the Novel Enzyme Replacement Therapy Avalglucosidase Alfa (Neogaa) in Treatment-naïve and Alglucosidase Alfa-Treated Patients With Late-Onset Pompe Disease: A Phase 1 Open-Label Multicenter Multinational Ascending Dose Study, Loren D.M. Pena, Richard J. Barohn, Barry J. Byrne, Claude Desnuelle, Ozlem Goker-Alpan, Shafeeq S. Ladha, Pascal Laforêt, Karl Eugen Mengel, Alan Pestronk, Jean Pouget, Benedikt Schoser, Volker Straub, Jaya Trivedi, Philip Van Damme, John Vissing, Peter Young, Katherine Kacena, Raheel Shafi, Beth L. Thurberg, and et al.


Lewy Body Dementia Association's Research Centers of Excellence Program: Inaugural Meeting Proceedings, Bethany Peterson, Melissa Armstrong, Douglas Galasko, James E. Galvin, Jennifer Goldman, David Irwin, Henry Paulson, Daniel Kaufer, James Leverenz, Angela Lunde, Ian G. McKeith, Andrew Siderowf, Angela Taylor, Katherine Amodeo, Matt Barrett, Kimiko Domoto-Reilly, John Duda, Stephen Gomperts, Holly A. Shill, and et al.


ALS Longitudinal Studies With Frequent Data Collection at Home: Study Design and Baseline Data, Seward B. Rutkove, Kristin Qi, Kerisa Shelton, Julie Liss, Visar Berisha, and Jeremy M. Shefner

Lewy Body Pathology in Alzheimer's Disease: A Clinicopathological Prospective Study, Rodolfo Savica, Thomas G. Beach, Joseph G. Hentz, Marwan N. Sabbagh, Geidy E. Serrano, Lucia I. Sue, Brittany N. Dugger, Holly A. Shill, Erika Driver-Dunckley, John N. Caviness, Shyamal H. Mehta, Sandra A. Jacobson, Christine M. Belden, Kathryn J. Davis, Edward Zamrini, David R. Shprecher, and Charles H. Adler


A Phase III Trial of Tirasemtiv as a Potential Treatment for Amyotrophic Lateral Sclerosis, Jeremy M. Shefner, Merit E. Cudkowicz, Orla Hardiman, Bettina M. Cockroft, Jacqueline H. Lee, Fady I. Malik, Lisa Meng, Stacy A. Rudnicki, Andrew A. Wolff, and Jinsy A. Andrews

A Prospective Study on Gait Dominant Normal Pressure Hydrocephalus, Melissa Song, Abraham N. Lieberman, Terry D. Fife, Megan Nielsen, Sharon Hayden, Marwan Sabbagh, and Jiong Shi

Altered Functional Network Topology Correlates With Clinical Measures in Very Early-Stage Drug-Naïve Parkinson's Disease, Karthik Sreenivasan, Virendra Mishra, Christopher Bird, Xiaowei Zhuang, Zhengshi Yang, Dietmar Cordes, and Ryan R. Walsh

Emergency Preparedness of Secondary School Athletic Programs in Arizona, Tamara C. Valovich and Javier F. Cardenas


Ketones Improves Apolipoprotein E4-Related Memory Deficiency Via Sirtuin 3, Junxiang Yin, Megan Nielsen, Shiping Li, and Jiong Shi

Submissions from 2018


Vitality-ALS a Phase III Trial of Tirasemtiv a Selective Fast Skeletal Muscle Troponin Activator as a Potential Treatment for Patients With Amyotrophic Lateral Sclerosis: Study Design and Baseline Characteristics, Jinsy A. Andrews, Merit E. Cudkowicz, Orla Hardiman, Lisa Meng, Amy Bian, Jacqueline Lee, Andrew A. Wolff, Fady I. Malik, and Jeremy M. Shefner

Association Between Decline in Slow Vital Capacity and Respiratory Insufficiency Use of Assisted Ventilation Tracheostomy Or Death in Patients With Amyotrophic Lateral Sclerosis, Jinsy A. Andrews, Lisa Meng, Sarah F. Kulke, Stacy A. Rudnicki, Andrew A. Wolff, Michael E. Bozik, Fady I. Malik, and Jeremy M. Shefner

Protective Effects of the Angiotensin II At 2 Receptor Agonist Compound 21 in Ischemic Stroke: A Nose-To-Brain Delivery Approach, Douglas M. Bennion, Chad H. Jones, Alex N. Dang, Jacob Isenberg, Justin T. Graham, Lena Lindblad, Oliver Domenig, Michael F. Waters, Marko Poglitsch, Colin Sumners, and Ulrike Muscha Steckelings

The Road Less Traveled, Anna D. Burke and William J. Burke

Association Between Pathology and Electroencephalographic Activity in Parkinson's Disease, John N. Caviness, Thomas G. Beach, Joseph G. Hentz, Holly A. Shill, Erika D. Driver-Dunckley, and Charles H. Adler

Intraoperative Test Stimulation Versus Stereotactic Accuracy as a Surgical End Point: A Comparison of Essential Tremor Outcomes After Ventral Intermediate Nucleus Deep Brain Stimulation, Tsinsue Chen, Zaman Mirzadeh, Kristina M. Chapple, Margaret Lambert, Virgilio G. Evidente, Guillermo Moguel-Cobos, Srivadee Oravivattanakul, Padma R. Mahant, and Francisco A. Ponce

A Randomized Phase II Study of Everolimus in Combination With Chemoradiation in Newly Diagnosed Glioblastoma: Results of NRG Oncology RTOG 0913, Prakash Chinnaiyan, Minhee Won, Patrick Y. Wen, Amyn M. Rojiani, Maria Werner-Wasik, Helen A. Shih, Lynn S. Ashby, Hsiang Hsuan Michael Yu, Volker W. Stieber, Shawn C. Malone, John B. Fiveash, Nimish A. Mohile, Manmeet S. Ahluwalia, Merideth M. Wendland, Philip J. Stella, Andrew Y. Kee, and Minesh P. Mehta

Reliability of the Sway Balance Mobile Application: A Retrospective Analysis, Kristina L. Dunn, R. Curtis Bay, Javier F. Cardenas, Matthew Anastasi, Tamara C. Valovich McLeod, and Richelle M. Williams

National Football League Head Neck and Spine Committee's Concussion Diagnosis and Management Protocol: 2017-18 Season, Richard G. Ellenbogen, Hunt Batjer, Javier F. Cardenas, Mitchel Berger, Julian Bailes, Elizabeth Pieroth, Robert Heyer, Nicholas Theodore, Wellington Hsu, Elizabeth Nabel, Joe Maroon, Robert Cantu, Ronnie Barnes, James Collins, Margot Putukian, Russell Lonser, Gary Solomon, and Allen Sills


Bilateral Vestibular Dysfunction Associated With Chronic Exposure to Military Jet Propellant Type-Eight Jet Fuel, Terry D. Fife, Michael J A Robb, Kristen K. Steenerson, and Kamala C. Saha

Vestibular Evoked Myogenic Potential Testing Payment Policy Review for Clinicians and Payers, Terry D. Fife, Saty Satya-Murti, Robert F. Burkard, and John P. Carey


Dynamical Properties of Postural Control in Obese Community-Dwelling Older Adults, Christopher W. Frames, Rahul Soangra, Thurmon E. Lockhart, John Lach, Dong Sam Ha, Karen A. Roberto, and Abraham N. Lieberman

Biomarkers of Cognitive Impairment, Ladan Ghazi-Saidi, Ryan R. Walsh, Guogen Shan, and Sarah J. Banks

Relationships Between Slow Vital Capacity and Measures of Respiratory Function on the ALSFRS-R, Carlayne Jackson, Mamede De Carvalho, Angela Genge, Terry Heiman-Patterson, Jeremy M. Shefner, Jenny Wei, and Andrew A. Wolff

Activation of JAK/STAT3 Restores NK-Cell Function and Improves Immune Defense After Brain Ischemia, Wei Na Jin, Andrew F. Ducruet, Qiang Liu, Samuel Xiang Yu Shi, Michael F. Waters, Ming Zou, Kevin N. Sheth, Rayna Gonzales, and Fu-Dong Shi

C-Terminal Proline Deletions in KCNC3 Cause Delayed Channel Inactivation and an Adult-Onset Progressive SCA13 With Spasticity, Swati Khare, Kira Galeano, Yalan Zhang, Jerelyn A. Nick, Harry S. Nick, S. H. Subramony, Jacinda Sampson, Leonard K. Kaczmarek, and Michael F. Waters


Respiratory Measures in Amyotrophic Lateral Sclerosis, Noah Lechtzin, Merit E. Cudkowicz, Mamede de Carvalho, Angela Genge, Orla Hardiman, Hiroshi Mitsumoto, Jesus S. Mora, Jeremy M. Shefner, Leonard H. Van, and Jinsy A. Andrews

Deep Brain Stimulation Targeting the Fornix for Mild Alzheimer Dementia (The Advance Trial): A two Year Follow-Up Including Results of Delayed Activation, Jeannie Marie S. Leoutsakos, Haijuan Yan, William S. Anderson, Wael F. Asaad, Gordon Baltuch, Anna D. Burke, M. Mallar Chakravarty, Kristen E. Drake, Kelly D. Foote, Lisa Fosdick, Peter Giacobbe, Zoltan Mari, Mary Pat McAndrews, Cynthia A. Munro, Esther S. Oh, Michael S. Okun, Jo Cara Pendergrass, Francisco A. Ponce, Paul B. Rosenberg, and et al.

Identification of Therapeutic Targets in Chordoma Through Comprehensive Genomic and Transcriptomic Analyses, Winnie S. Liang, Christopher Dardis, Adrienne Helland, Shobana Sekar, Jonathan Adkins, Lori Cuyugan, Daniel Enriquez, Sara Byron, and Andrew S. Little

Downward Finger Displacement Distinguishes Parkinson Disease Dementia From Alzheimer Disease, Abraham N. Lieberman, Aman Deep, Jiong Shi, Rohit Dhall, Saulena Shafer, Guillermo Moguel-Cobos, Ravneet Dhillon, Christopher W. Frames, and Margaret McCauley

Engineered Agrin Attenuates the Severity of Experimental Autoimmune Myasthenia Gravis, Zhiguo Li, Minshu Li, Kristofer Wood, Steffan Hettwer, Suraj Ashok Muley, Fu-Dong Shi, Qiang Liu, and Shafeeq S. Ladha


Profile of Medical Care Costs in Patients With Amyotrophic Lateral Sclerosis in the Medicare Programme and Under Commercial Insurance, Lisa Meng, Amy Bian, Scott Jordan, Andrew Wolff, Jeremy M. Shefner, and Jinsy Andrews

Immunohistochemistry and Electrophysiological Findings in Swine Abattoir Workers With Immune-Mediated Polyradiculoneuropathy, Suraj Ashok Muley, Stacy Holzbauer, Brent Clark, James Sejvar, Ruth Lynfield, Gareth Parry, and Aaron S. DeVries

Implementing Motor Unit Number Index (Munix) in a Large Clinical Trial: Real World Experience From 27 Centres, Christoph Neuwirth, Nathalie Braun, Kristl G. Claeys, Robert Bucelli, Christina Fournier, Mark Bromberg, Susanne Petri, Stephan Goedee, Timothy Lenglet, Ron Leppanen, Antonio Canosa, Ira Goodman, Muhammad Al-Lozi, Takuya Ohkubo, Annemarie Hübers, Nazem Atassi, Agessandro Abrahao, Andreas Funke, Shafeeq S. Ladha, and et al.


Motor Subtypes of Parkinson's Disease can be Identified by Frequency Component of Postural Stability, Saba Rezvanian, Thurmon Lockhart, Christopher Frames, Rahul Soangra, and Abraham N. Lieberman

Intermediate-Risk Meningioma: Initial Outcomes From NRG Oncology RTOG 0539, Leland Rogers, Peixin Zhang, Michael A. Vogelbaum, Arie Perry, Lynn S. Ashby, Jignesh M. Modi, Anthony M. Alleman, James Galvin, David Brachman, Joseph M. Jenrette, John De Groot, Joseph A. Bovi, Maria Werner-Wasik, Jonathan P.S. Knisely, and Minesh P. Mehta

Salivary Beta Amyloid Protein Levels Are Detectable and Differentiate Patients With Alzheimer's Disease Dementia From Normal Controls: Preliminary Findings, Marwan N. Sabbagh, Jiong Shi, Moonhee Lee, Lisa Arnold, Yazan Al-Hasan, Jennifer Heim, and Patrick McGeer

Outcomes After Hemispherectomy in Adult Patients With Intractable Epilepsy: Institutional Experience and Systematic Review of the Literature, Courtney M. Schusse, Kris A. Smith, and Cornelia Drees

Reducing Sample Size Requirements for Future ALS Clinical Trials With a Dedicated Electrical Impedance Myography System, Jeremy M. Shefner, Seward B. Rutkove, James B. Caress, Michael Benatar, William S. David, Michael S. Cartwright, Eric A. Macklin, and Jose L. Bohorquez

Predicting Alpha-Synuclein Pathology by Rem Sleep Behavior Disorder Diagnosis, David R. Shprecher, Charles H. Adler, Nan Zhang, Joseph G. Hentz, Geidy E. Serrano, Brittany N. Dugger, Holly A. Shill, Rodolfo Savica, John N. Caviness, Marwan N. Sabbagh, Christine M. Belden, Erika Driver-Dunckley, Shyamal H. Mehta, Lucia I. Sue, Kathryn J. Davis, Edward Zamrini, and Thomas G. Beach

Assessment of Bulbar Function in Amyotrophic Lateral Sclerosis: Validation of a Self-Report Scale (Center for Neurologic Study Bulbar Function Scale), R. A. Smith, E. A. Macklin, K. J. Myers, G. L. Pattee, K. L. Goslin, G. D. Meekins, J. R. Green, Jeremy M. Shefner, and E. P. Pioro

Fingolimod Enhances the Efficacy of Delayed Alteplase Administration in Acute Ischemic Stroke by Promoting Anterograde Reperfusion and Retrograde Collateral Flow, De Cai Tian, Kaibin Shi, Zilong Zhu, Jia Yao, Xiaoxia Yang, Lei Su, Sheng Zhang, Meixia Zhang, Rayna J. Gonzales, Qiang Liu, De Ren Huang, Michael F. Waters, Kevin N. Sheth, Andrew F. Ducruet, Ying Fu, Min Lou, and Fu-Dong Shi

Recommendations of the Global Multiple System Atrophy Research Roadmap Meeting, Ryan R. Walsh, Florian Krismer, Wendy R. Galpern, Gregor K. Wenning, Phillip A. Low, Glenda Halliday, Walter J. Koroshetz, Janice Holton, Niall P. Quinn, Olivier Rascol, Leslie M. Shaw, David Eidelberg, Pam Bower, Jeffrey L. Cummings, Victor Abler, Judy Biedenharn, Gal Bitan, David J. Brooks, Patrik Brundin, and et al.

Coding of Episodic Memory in the Human Hippocampus, John T. Wixted, Stephen D. Goldinger, Larry R. Squire, Joel R. Kuhn, Megan H. Papesh, Kris A. Smith, David M. Treiman, and Peter N. Steinmetz

Use of Flutemetamol F18-Labeled Positron Emission Tomography and Other Biomarkers to Assess Risk of Clinical Progression in Patients With Amnestic Mild Cognitive Impairment, David A. Wolk, Carl Sadowsky, Beth Safirstein, Juha O. Rinne, Ranjan Duara, Richard Perry, Marc Agronin, Jose Gamez, Jiong Shi, Adrian Ivanoiu, Lennart Minthon, Zuzana Walker, Steen Hasselbalch, Clive Holmes, Marwan Sabbagh, Marilyn Albert, Adam Fleisher, Paul Loughlin, Eric Triau, and et al.

An Extent of Resection Threshold for Seizure Freedom in Patients With Low-Grade Gliomas, David S. Xu, Al Wala Awad, Chad Mehalechko, Jeffrey R. Wilson, Lynn S. Ashby, Stephen W. Coons, and Nader Sanai

Amyloid-Beta Increases Tau by Mediating Sirtuin 3 in Alzheimer's Disease, Junxiang Yin, Pengcheng Han, Melissa Song, Megan Nielsen, Thomas G. Beach, Geidy E. Serrano, Winnie S. Liang, Richard J. Caselli, and Jiong Shi


Sirtuin 3 Attenuates Amyloid-Beta Induced Neuronal Hypometabolism, Junxiang Yin, Shiping Li, Megan Nielsen, Tanner Carcione, Winnie S. Liang, and Jiong Shi

Incorporating Spatial Constraint in Co-Activation Pattern Analysis to Explore the Dynamics of Resting-State Networks: An Application to Parkinson's Disease, Xiaowei Zhuang, Ryan R. Walsh, Karthik Sreenivasan, Zhengshi Yang, Virendra Mishra, and Dietmar Cordes

Submissions from 2017

GBA Mutations in Parkinson Disease: Earlier Death But Similar Neuropathological Features, C. H. Adler, T. G. Beach, Holly A. Shill, John N. Caviness, E. Driver-Dunckley, M. N. Sabbagh, A. Patel, L. I. Sue, G. Serrano, S. A. Jacobson, K. Davis, C. M. Belden, B. N. Dugger, S. A. Paciga, A. R. Winslow, W. D. Hirst, and J. G. Hentz

Essential Tremor and Depression, Sana Aslam, Nan Zhang, Charles H. Adler, John N. Caviness, Erika Driver-Dunckley, Shyamal H. Mehta, Marwan N. Sabbagh, Christine Belden, Edward Zamrini, Thomas G. Beach, and Holly A. Shill

Clinical Practice Guideline: Benign Paroxysmal Positional Vertigo (Update), Neil Bhattacharyya, Samuel P. Gubbels, Seth R. Schwartz, Jonathan A. Edlow, Hussam El-Kashlan, Terry D. Fife, Janene M. Holmberg, Kathryn Mahoney, Deena B. Hollingsworth, Richard Roberts, Michael D. Seidman, Robert W. Prasaad Steiner, Betty Tsai Do, Courtney C J Voelker, Richard W. Waguespack, and Maureen D. Corrigan

Clinical Practice Guideline: Benign Paroxysmal Positional Vertigo (Update) Executive Summary, Neil Bhattacharyya, Samuel P. Gubbels, Seth R. Schwartz, Jonathan A. Edlow, Hussam El-Kashlan, Terry D. Fife, Janene M. Holmberg, Kathryn Mahoney, Deena B. Hollingsworth, Richard Roberts, Michael D. Seidman, Robert W. Prasaad Steiner, Betty Tsai Do, Courtney C J Voelker, Richard W. Waguespack, and Maureen D. Corrigan

Stroke Hospital Characteristics in the Florida-Puerto Rico Collaboration to Reduce Stroke Disparities Study, Maria A. Ciliberti-Vargas, Hannah Gardener, Kefeng Wang, Chuanhui Dong, Li Yi, Jose G. Romano, Mary Robichaux, Salina P. Waddy, Ulises Nobo, Sandra Diaz-Acosta, Tatjana Rundek, Michael F. Waters, and Ralph L. Sacco


Atypical Teratoid Rhabdoid Tumor: two Case Reports and an Analysis of Adult Cases With Implications for Pathophysiology and Treatment, Christopher Dardis, Jared Yeo, Kelly Milton, Lynn S. Ashby, Kris A. Smith, Shwetal Mehta, Emad Youssef, Jenny Eschbacher, Kathy Tucker, Laughlin Dawes, Neil Lambie, Elizabeth Algar, and Elizabeth Hovey

Poor Safety and Tolerability Hamper Reaching a Potentially Therapeutic Dose in the Use of Thalidomide for Alzheimer's Disease: Results From a Double-Blind Placebo-Controlled Trial, Boris Decourt, Denise Drumm-Gurnee, Jeffrey Wilson, Sandra Jacobson, Christine Belden, Sherye Sirrel, Michael Ahmadi, Holly A. Shill, Jessica Powell, Aaron Walker, Amanda Gonzales, Mimi Macias, and Marwan N. Sabbagh

Magnetoencephalography and New Imaging Modalities in Epilepsy, Jessica Falco-Walter, Christian Owen, Mishu Sharma, Christopher Reggi, Mandy Yu, Travis R. Stoub, and Michael A. Stein

Dizziness in the Outpatient Care Setting, Terry D. Fife


Practice Guideline: Cervical and Ocular Vestibular Evokedmyogenic Potential Testing: Report of the Guideline Development Dissemination and Implementation Subcommittee of the American Academy of Neurology, Terry D. Fife, James G. Colebatch, Kevin A. Kerber, Krister Brantberg, Michael Strupp, Hyung Lee, Mark F. Walker, Eric Ashman, Jeffrey Fletcher, Brian Callaghan, and David S. Gloss

Poly(GP) Proteins Are a Useful Pharmacodynamic Marker for C9ORF72-Associated Amyotrophic Lateral Sclerosis, Tania F. Gendron, Jeannie Chew, Jeannette N. Stankowski, Lindsey R. Hayes, Yong Jie Zhang, Mercedes Prudencio, Yari Carlomagno, Lillian M. Daughrity, Karen Jansen-West, Emilie A. Perkerson, Aliesha O'Raw, Casey Cook, Luc Pregent, Veronique Belzil, Marka Van Blitterswijk, Lilia J. Tabassian, Chris W. Lee, Mei Yue, Shafeeq S. Ladha, and et al.


Improved Diagnosis of Parkinson's Disease From a Detailed Olfactory Phenotype, Richard C. Gerkin, Charles H. Adler, Joseph G. Hentz, Holly A. Shill, Erika Driver-Dunckley, Shyamal H. Mehta, Marwan N. Sabbagh, John N. Caviness, Brittany N. Dugger, Geidy Serrano, Christine Belden, Brian H. Smith, Lucia Sue, Kathryn J. Davis, Edward Zamrini, and Thomas G. Beach


The Impact of Aging on Brain Pituitary Adenylate Cyclase Activating Polypeptide Pathology and Cognition in Mice and Rhesus Macaques, Pengcheng Han, Megan Nielsen, Melissa Song, Junxiang Yin, Michele R. Permenter, Julie A. Vogt, James R. Engle, Brittany N. Dugger, Thomas G. Beach, Carol A. Barnes, and Jiong Shi

A Quantitative Analysis of Brain Soluble Tau and the Tau Secretion Factor, Pengcheng Han, Geidy Serrano, Thomas G. Beach, Richard J. Caselli, Junxiang Yin, Ningning Zhuang, and Jiong Shi


Single Neuron Recordings of Bilinguals Performing in a Continuous Recognition Memory Task, Erika K. Hussey, Kiel Christianson, David M. Treiman, Kris A. Smith, and Peter N. Steinmetz

ACR Appropriateness Criteria(R) Tinnitus, Marcus M. Kessler, Marwan Moussa, Julie Bykowski, Claudia F E Kirsch, Joseph M. Aulino, Kevin L. Berger, Asim F. Choudhri, Terry D. Fife, Isabelle M. Germano, A. Tuba Kendi, Jeffrey H. Kim, Michael D. Luttrull, Diego Nunez, Lubdha M. Shah, Aseem Sharma, Vilaas S. Shetty, Sophia C. Symko, and Rebecca S. Cornelius


Immune Modulation in the Treatment of Amyotrophic Lateral Sclerosis: A Review of Clinical Trials, Syed I. Khalid, Leonel Ampie, Ryan Kelly, Shafeeq S. Ladha, and Christopher Dardis


A KCNC3 Mutation Causes a Neurodevelopmental Non-Progressive SCA13 Subtype Associated With Dominant Negative Effects and Aberrant EGFR Trafficking, Swati Khare, Jerelyn A. Nick, Yalan Zhang, Kira Galeano, Brittany Butler, Habibeh Khoshbouei, Sruti Rayaprolu, Tyisha Hathorn, Laura P. Ranum, Lisa Smithson, Todd E. Golde, Martin Paucar, Richard Morse, Michael Raff, Julie Simon, Magnus Nordenskjold, Karin Wirdefeldt, Diego E. Rincon-Limas, Michael F. Waters, and et al.

Polestriding Intervention Improves Gait and Axial Symptoms in Mild to Moderate Parkinson Disease, Narayanan Krishnamurthi, Holly A. Shill, Darolyn O'Donnell, Padma R. Mahant, Johan Samanta, Abraham N. Lieberman, and James Abbas


Abnormal Capillary Vasodynamics Contribute to Ictal Neurodegeneration in Epilepsy, Rocio Leal-Campanario, Luis Alarcon-Martinez, Hector Rieiro, Susana Martinez-Conde, Tugba Alarcon-Martinez, Xiuli Zhao, Jonathan LaMee, Pamela J. Osborn, Michael E. Calhoun, Juan I. Arribas, Alexander A. Schlegel, Leandro L. Di Stasi, Jong M. Rho, Landon Inge, Jorge Otero-Millan, David M. Treiman, and Stephen L. Macknik

Incidence and Predictors of Dural Venous Sinus Pressure Gradient in Idiopathic Intracranial Hypertension and Non-Idiopathic Intracranial Hypertension Headache Patients: Results From 164 Cerebral Venograms, Michael R. Levitt, Randall J. Hlubek, Karam Moon, M. Yashar Kalani, Peter Nakaji, Kris A. Smith, Andrew S. Little, Kerry Knievel, Jane W. Chan, Cameron G. McDougall, and Felipe C. Albuquerque

Why Do Trials for Alzheimer's Disease Drugs Keep Failing? a Discontinued Drug Perspective for 2010-2015, Dev Mehta, Robert Jackson, Gaurav Paul, Jiong Shi, and Marwan Sabbagh

Safety and Efficacy of Ozanezumab in Patients With Amyotrophic Lateral Sclerosis: A Randomised Double-Blind Placebo-Controlled Phase 2 Trial, Vincent Meininger, Angela Genge, Leonard H. van den Berg, Wim Robberecht, Albert Ludolph, Adriano Chio, Seung H. Kim, P. Nigel Leigh, Matthew C. Kiernan, Jeremy M. Shefner, Claude Desnuelle, Karen E. Morrison, Susanne Petri, Diane Boswell, Jane Temple, Rajat Mohindra, Matt Davies, Jonathan Bullman, Paul Rees, and et al.


Psychogenic Movement Disorders and Dopamine Transporter Scans: Still a Clinical Diagnosis?, Guillermo Moguel-Cobos, Zane Maroney, Jennifer M. Erickson, Alexander I. Tröster, and Davin K. Quinn

Phase II Study of Medi-575 an Anti-Platelet-Derived Growth Factor-Alpha Antibody in Patients With Recurrent Glioblastoma, Surasak Phuphanich, Jeffrey Raizer, Marc Chamberlain, Paola Canelos, Rajesh Narwal, Shengyan Hong, Robert Miday, Minal Nade, and Kevin Laubscher


Increasing Precision of Clinical Diagnosis of Alzheimer's Disease Using a Combined Algorithm Incorporating Clinical and Novel Biomarker Data, Marwan N. Sabbagh, Lih Fen Lue, Daniel Fayard, and Jiong Shi


Racial-Ethnic Disparities in Acute Stroke Care in the Florida-Puerto Rico Collaboration to Reduce Stroke Disparities Study, Ralph L. Sacco, Hannah Gardener, Kefeng Wang, Chuanhui Dong, Maria A. Ciliberti-Vargas, Carolina M. Gutierrez, Negar Asdaghi, W. Scott Burgin, Olveen Carrasquillo, Enid J. Garcia-Rivera, Ulises Nobo, Sofia Oluwole, David Z. Rose, Michael F. Waters, Juan Carlos Zevallos, Mary Robichaux, Salina P. Waddy, Jose G. Romano, Tatjana Rundek, and et al.

Performance of [18F]Flutemetamol Amyloid Imaging Against the Neuritic Plaque Component of Cerad and the Current (2012) NIA-AA Recommendations for the Neuropathologic Diagnosis of Alzheimer's Disease, Stephen Salloway, Jose E. Gamez, Upinder Singh, Carl H. Sadowsky, Teresa Villena, Marwan N. Sabbagh, Thomas G. Beach, Ranjan Duara, Adam S. Fleisher, Kirk A. Frey, Zuzana Walker, Arvinder Hunjan, Yavir M. Escovar, Marc E. Agronin, Joel Ross, Andrea Bozoki, Mary Akinola, Jiong Shi, Rik Vandenberghe, and et al.

Strength Testing in Motor Neuron Diseases, Jeremy M. Shefner


Hippocampal Synaptic and Neural Network Deficits in Young Mice Carrying the Human APOE4 Gene, Guo Zhu Sun, Yong Chang He, Xiao Kuang Ma, Shuang Tao Li, De Jie Chen, Ming Gao, Shen Feng Qiu, Jun Xiang Yin, Jiong Shi, and Jie Wu

The Concept of Effective Inflow: Application to Interictal Localization of the Epileptogenic Focus From IEEG, Ioannis Vlachos, Balu Krishnan, David M. Treiman, Konstantinos Tsakalis, Dimitris Kugiumtzis, and Leon D. Iasemidis

Benign Paroxysmal Positional Vertigo: Diagnostic Criteria Consensus Document of the Committee for the Classification of Vestibular Disorders of the Bárány Society, Michael Von Brevern, Pierre Bertholon, Thomas Brandt, Terry D. Fife, Takao Imai, Daniele Nuti, and David Newman-Toker

Benign Paroxysmal Positional Vertigo: Diagnostic Criteria, Michael Von Brevern, Pierre Bertholon, Thomas Brandt, Terry D. Fife, Takao Imai, Daniele Nuti, David Newman-Toker, Shuang Mei Yan, Huan Zhang, Xu Yang, and Zi Ming Wu

Rindopepimut With Temozolomide for Patients With Newly Diagnosed EGFRVIII-Expressing Glioblastoma (Act IV): A Randomised Double-Blind International Phase 3 Trial, Michael Weller, Nicholas Butowski, David D. Tran, Lawrence D. Recht, Michael Lim, Hal Hirte, Lynn S. Ashby, Laszlo Mechtler, Samuel A. Goldlust, Fabio Iwamoto, Jan Drappatz, Donald M. O'Rourke, Mark Wong, Mark G. Hamilton, Gaetano Finocchiaro, James Perry, Wolfgang Wick, Jennifer Green, Yi He, and et al.

Use of Intracranial Pressure Monitoring Frequently Refutes Diagnosis of Idiopathic Intracranial Hypertension, David S. Xu, Randall J. Hlubek, Celene B. Mulholland, Kerry Knievel, Kris A. Smith, and Peter Nakaji