The Influence of CYP2B6 Variants and Administration of Propofol on Patient Outcomes after Traumatic Brain Injury.

Authors

Katherine O'Meara
Ava M Puccio
Dianxu Ren
Sandra Deslouches
Ruchira M. Jha, Department of Neurology, Barrow Neurological Institute, Phoenix, Arizona, USA.Follow
David O Okonkwo
Yvette P Conley

Document Type

Article

Abstract

Management of severe traumatic brain injury (sTBI) typically involves the use of sedation, which inherently results in benefits and risks. The cytochrome P450 enzyme CYP2B6 is involved in the biotransformation of particular drug classes, including many intravenous sedatives. Variants of the

Publication Date

1-1-2024

Publication Title

Neurotrauma Rep

ISSN

2689-288X

Volume

5

Issue

1

First Page

680

Last Page

685

PubMed ID

39071983

Digital Object Identifier (DOI)

10.1089/neur.2024.0025

Recommended Citation

O'Meara, Katherine; Puccio, Ava M; Ren, Dianxu; Deslouches, Sandra; Jha, Ruchira M.; Okonkwo, David O; and Conley, Yvette P, "The Influence of CYP2B6 Variants and Administration of Propofol on Patient Outcomes after Traumatic Brain Injury." (2024). Neurology. 1883.
https://scholar.barrowneuro.org/neurology/1883