The Barrow Neurological Institute is proud of its reputation as a medical research facility and is home to some of the most sophisticated research programs outside of an academic setting in the Southwestern United States. Researchers in the Barrow Neurosurgery Research Center are devoted to learning more about the causes of and treatments for a wide range of disorders, such as stroke, aneurysms, spinal cord injury, and hydrocephalus. Our research has led to treatments that are being used around the world. Within the Department are neurosurgeons who subspecialize in cerebrovascular and skull base, functional and stereotactic, pediatric, spine, tumor, and endovascular neurosurgery.

Physicians, scientists, and expert clinical staff come together with a commitment to developing new techniques for the prevention, diagnosis, treatment, and rehabilitation of neurological illnesses and injuries. The leadership of internationally respected physicians keeps Barrow at the forefront of neuroscience. The compassionate expertise of its extensive staff of nurses, technologists, therapists and support personnel is evident in every aspect of care provided.

Our mission is to advance the knowledge and practice of medicine in neuroscience through basic and clinical research, education of medical professionals, and innovation in clinical techniques and technology.

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Submissions from 2012

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Reply: Mild cognitive impairment in de novo Parkinson's disease according to Movement Disorder guidelines, Irene Litvan, Jennifer G. Goldman, Alex I. Tröster, Ben A. Schmand, and Dan Weintraub

Subthalamic deep brain stimulation with a constant-current device in Parkinson's disease: an open-label randomised controlled trial., Michael S Okun, Bruno V Gallo, George Mandybur, Jonathan Jagid, Kelly D Foote, Fredy J Revilla, Ron Alterman, Joseph Jankovic, Richard Simpson, Fred Junn, Leo Verhagen, Jeff E Arle, Blair Ford, Robert R Goodman, R Malcolm Stewart, Stacy Horn, Gordon H Baltuch, Brian H Kopell, Frederick Marshall, Delea Peichel, Rajesh Pahwa, Kelly E Lyons, Alexander I Tröster, Jerrold L Vitek, and Michele Tagliati

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Subthalamic deep brain stimulation with a constant-current device in Parkinson's disease: An open-label randomised controlled trial, Michael S. Okun, Bruno V. Gallo, George Mandybur, Jonathan Jagid, Kelly D. Foote, Fredy J. Revilla, Ron Alterman, Joseph Jankovic, Richard Simpson, Fred Junn, Leo Verhagen, Jeff E. Arle, Blair Ford, Robert R. Goodman, R. Malcolm Stewart, Stacy Horn, Gordon H. Baltuch, Brian H. Kopell, Frederick Marshall, De Lea Peichel, Rajesh Pahwa, Kelly E. Lyons, Alexander I. Tröster, Jerrold L. Vitek, and Michele Tagliati

Submissions from 2011

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Current serum lipoprotein levels and fMRI response to working memory in midlife, Mitzi M. Gonzales, Takashi Tarumi, Danielle E. Eagan, Hirofumi Tanaka, Fedora O. Biney, and Andreana P. Haley

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Functional magnetic resonance imaging of working memory reveals frontal hypoactivation in middle-aged adults with cognitive complaints, Andreana P. Haley, Danielle E. Eagan, Mitzi M. Gonzales, Fedora O. Biney, and Rachel A. Cooper

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MDS task force on mild cognitive impairment in Parkinson's disease: Critical review of PD-MCI, Irene Litvan, Dag Aarsland, Charles H. Adler, Jennifer G. Goldman, Jaime Kulisevsky, Brit Mollenhauer, Maria C. Rodriguez-Oroz, Alexander I. Tröster, and Daniel Weintraub

Strain differences in self-administration of methylphenidate and sucrose pellets in a rat model of attention-deficit hyperactivity disorder., Julie A Marusich, William Travis McCuddy, Joshua S Beckmann, Cassandra D Gipson, and Michael T Bardo

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Surgical resection of hypothalamic hamartomas for severe behavioral symptoms, Yu tze Ng, Eric V. Hastriter, Jennifer Wethe, Kevin E. Chapman, Erin C. Prenger, George P. Prigatano, Tracy Oppenheim, Maggie Varland, Harold L. Rekate, and John F. Kerrigan

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The importance of the patient's subjective experience in stroke rehabilitation, George P. Prigatano

The current status of postconcussion syndrome, George P. Prigatano and Shawn D. Gale

Anosognosia for hemiplegia with preserved awareness of complete cortical blindness following intracranial hemorrhage., George P Prigatano, Jessica Matthes, Stacy W Hill, Thomas R Wolf, and Joseph E Heiserman

Anosognosia for hemiplegia with preserved awareness of complete cortical blindness following intracranial hemorrhage, George P. Prigatano, Jessica Matthes, Stacy W. Hill, Thomas R. Wolf, and Joseph E. Heiserman

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A Differential Deficit in Time- Versus Event-Based Prospective Memory in Parkinson's Disease, Sarah A. Raskin, Steven Paul Woods, Amelia J. Poquette, April B. McTaggart, Jim Sethna, Rebecca C. Williams, and Alexander I. Tröster

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Patterns of deficits in daily functioning and cognitive performance of patients with Alzheimer disease, Jill Razani, Stacey Bayan, Cynthia Funes, Nouran Mahmoud, Nicole Torrence, Jennifer Wong, Cathy Alessi, and Karen Josephson

Manganese accumulation in the olfactory bulbs and other brain regions of "asymptomatic" welders, Suman Sen, Michael R. Flynn, Guangwei Du, Alexander I. Tröster, Hongyu An, and Xuemei Huang

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A Précis of recent advances in the neuropsychology of mild cognitive impairment(s) in Parkinson's disease and a proposal of preliminary research criteria, Alexander I. Tröster

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Parkinson disease: Deep brain stimulation and neuropsychology: A step forward?, Alexander I. Tröster

Deep brain stimulation and neuropsychology: a step forward?, Alexander I. Tröster

Submissions from 2010

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On age differences in prefrontal function: The importance of emotional/cognitive integration, Elsa Baena, Philip A. Allen, Kevin P. Kaut, and Rosalie J. Hall

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A recommended scale for cognitive screening in clinical trials of Parkinson's disease, Kelvin L. Chou, Melissa M. Amick, Jason Brandt, Richard Camicioli, Karen Frei, Darren Gitelman, Jennifer Goldman, John Growdon, Howard I. Hurtig, Bonnie Levin, Irene Litvan, Laura Marsh, Tanya Simuni, Alexander I. Tröster, and Ergun Y. Uc

The impact of antidepressant treatment on cognitive functioning in depressed patients with Parkinson's disease, Roseanne DeFronzo Dobkin, Matthew Menza, Karina L. Bienfait, Michael Gara, Humberto Marin, Margery H. Mark, Allison Dicke, and Alexander Tröster

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Deep white matter volume loss and social reintegration after traumatic brain injury in children, Shawn D. Gale and George P. Prigatano

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Neural mechanisms of context effects on face recognition: Automatic binding and context shift decrements, Scott M. Hayes, Elsa Baena, Trong Kha Truong, and Roberto Cabeza

Cognitive rehabilitation for military personnel with mild traumatic brain injury and chronic post-concussional disorder: Results of April 2009 consensus conference., Katherine Helmick, Members of Consensus Conference Collaborators, and George Prigatano

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Advancing the profession of clinical neuropsychology with appropriate outcome studies and Demonstrated clinical skills, George P. Prigatano and Jeannine Morrone-Strupinsky

Submissions from 2009

Age-related networks of regional covariance in MRI gray matter: reproducible multivariate patterns in healthy aging, Kaitlin L. Bergfield, Krista D. Hanson, Kewei Chen, Stefan J. Teipel, Harald Hampel, Stanley I. Rapoport, James R. Moeller, and Gene E. Alexander

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Anosognosia: Clinical and ethical considerations, George P. Prigatano

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Self-appraisal and objective assessment of cognitive and affective functioning in persons with epileptic and nonepileptic seizures, George P. Prigatano and Kristin A. Kirlin

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Neuropsychology of deep brain stimulation in neurology and psychiatry, Alexander I. Troster

Submissions from 2008

Scales to assess psychosis in Parkinson's disease: Critique and recommendations, Hubert H. Fernandez, Dag Aarsland, Gilles Fénelon, Joseph H. Friedman, Laura Marsh, Alexander I. Tröster, Werner Poewe, Olivier Rascol, Cristina Sampaio, Glenn T. Stebbins, and Christopher G. Goetz

Neuropsychology of dementia with Lewy bodies, Daniel I. Kaufer and Alexander I. Tröster

A holistic brain injury rehabilitation program for school-age children, Joseph T. Marcantuono and George P. Prigatano

Implicit depression and hopelessness in remitted depressed individuals., Tiffany M Meites, Christen M Deveney, Katherine T Steele, Avram J Holmes, and Diego A Pizzagalli

The problem of not developing normally and pediatric neuropsychological rehabilitation: theMitchell Rosenthal Lecture, George P. Prigatano

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Parental perspectives on recovery and social reintegration after pediatric traumatic Brain Injury, George P. Prigatano and Jennifer Gray

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Predictors of performance on three developmentally sensitive neuropsychological tests in children with and without traumatic brain injury, George P. Prigatano and Jennifer A. Gray

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Individual case analysis of processing speed difficulties in children with and without traumatic brain injury, George P. Prigatano, Jennifer A. Gray, and Shawn D. Gale

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Predictors of quantitative and qualitative Halstead finger-tapping scores in low socioeconomic status school-age children, George P. Prigatano, Jennifer A. Gray, and Joe Legacy

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Verbal (animal) fluency scores in age/grade appropriate minority children from low socioeconomic backgrounds, George P. Prigatano, Jennifer A. Gray, and Vicky T. Lomay

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Intellectual functioning in presurgical patients with hypothalamic hamartoma and refractory epilepsy, George P. Prigatano, Jennifer V. Wethe, Jennifer A. Gray, Norman Wang, Steven Chung, Yu Tze Ng, Erin Prenger, and John F. Kerrigan

Enhanced negative feedback responses in remitted depression., Diane L Santesso, Katherine T Steele, Ryan Bogdan, Avram J Holmes, Christen M Deveney, Tiffany M Meites, and Diego A Pizzagalli

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Short-term cognitive and affective outcomes after subthalamic deep brain stimulation for Parkinson's disease, Alexander I. Tröster

Neuropsychological characteristics of dementia with Lewy bodies and Parkinson's disease with dementia: differentiation, early detection, and implications for "mild cognitive impairment" and biomarkers, Alexander I. Tröster

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Executive dysfunction and neuropsychiatric symptoms predict lower health status in essential tremor, Steven Paul Woods, J. Cobb Scott, Julie A. Fields, Amelia Poquette, and Alexander I. Tröster

Submissions from 2007

Asymmetrical ventricular enlargement in Parkinson's disease, Xuemei Huang, Yueh Z. Lee, Martin McKeown, Guido Gerig, Hongbin Gu, Weili Lin, Mechelle M. Lewis, Sutapa Ford, Alexander I. Tröster, Daniel R. Weinberger, and Martin Styner

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Anosognosia for hemiplegia after stroke is a multifaceted phenomenon: A systematic review of the literature, M. D. Orfei, R. G. Robinson, G. P. Prigatano, S. Starkstein, N. Rüsch, P. Bria, C. Caltagirone, and G. Spalletta

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Cognitive and Behavioral Dysfunction in Children With Hypothalamic Hamartoma and Epilepsy, George P. Prigatano

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Parental concerns and distress after paediatric traumatic brain injury: A qualitative study, George P. Prigatano and Jennifer A. Gray

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Fuld Object Memory Evaluation adapted for school-age children, George P. Prigatano, Saurabh Gupta, and Shawn Gale

Assessing cognitive change in Parkinson's disease: development of practice effect-corrected reliable change indices, Alexander I. Tröster, Steven Paul Woods, and Erin E. Morgan

Submissions from 2006

Deep brain stimulation: postoperative issues, Günther Deuschl, Jan Herzog, Galit Kleiner-Fisman, Cynthia Kubu, Andres M. Lozano, Kelly E. Lyons, Maria C. Rodriguez-Oroz, Filippo Tamma, Alexander I. Tröster, Jerrold L. Vitek, Jens Volkmann, and Valerie Voon

Apolipoprotein E and dementia in Parkinson disease: a meta-analysis, Xuemei Huang, Peter Chen, Daniel I. Kaufer, Alexander I. Tröster, and Charles Poole

Deep brain stimulation: preoperative issues, Anthony E. Lang, Jean-Luc Houeto, Paul Krack, Cynthia Kubu, Kelly E. Lyons, Elena Moro, William Ondo, Rajesh Pahwa, Werner Poewe, Alexander I. Tröster, Ryan Uitti, and Valerie Voon

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Cognitive sequelae of subthalamic nucleus deep brain stimulation in Parkinson's disease: a meta-analysis, Thomas D. Parsons, Steven A. Rogers, Alyssa J. Braaten, Steven Paul Woods, and Alexander I. Tröster

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Friends after traumatic brain injury in children, George P. Prigatano and Saurabh Gupta

The use, education, training and supervision of neuropsychological test technicians (psychometrists) in clinical practice. Official statement of the National Academy of Neuropsychology, Antonio E. Puente, Russell Adams, William B. Barr, and Shane S. Bush

The importance of neuropsychological assessment for the evaluation of childhood learning disorders NAN Policy and Planning Committee, Cheryl H. Silver, Lynn B. Blackburn, Sharon Arffa, Jeffrey T. Barth, Shane S. Bush, Sandra P. Koffler, Neil H. Pliskin, Cecil R. Reynolds, Ronald M. Ruff, Alexander I. Tröster, Rosemarie S. Moser, and Robert W. Elliott

Absence of the apolipoprotein E epsilon4 allele is associated with working memory impairment in Parkinson's disease, Alexander I. Tröster, Julie A. Fields, Anthony M. Paolo, and William C. Koller

Deep brain stimulation: neuropsychological and neuropsychiatric issues, Valerie Voon, Cynthia Kubu, Paul Krack, Jean-Luc Houeto, and Alexander I. Tröster

Statistical power of studies examining the cognitive effects of subthalamic nucleus deep brain stimulation in Parkinson's disease, Steven Paul Woods, Julie D. Rippeth, Emily Conover, Catherine L. Carey, Thomas D. Parsons, and Alexander I. Tröster

Submissions from 2005

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Subjective reports of fatigue during early recovery from traumatic brain injury, Susan R. Borgaro, Jason Baker, Jennifer V. Wethe, George P. Prigatano, and Christina Kwasnica

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Symptom validity assessment: Practice issues and medical necessity: NAN Policy & Planning Committee, Shane S. Bush, Ronald M. Ruff, Alexander I. Tröster, Jeffrey T. Barth, Sandra P. Koffler, Neil H. Pliskin, Cecil R. Reynolds, and Cheryl H. Silver

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Patients' and relatives' reports of disturbances 9 months after stroke: Subjective changes in physical functioning, cognition, emotion, and behavior, Jacqueline Hochstenbach, George Prigatano, and Theo Mulder

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Disturbances of self-awareness and rehabilitation of patients with traumatic brain injury: A 20-year perspective, George P. Prigatano

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Awareness and distress after traumatic brain injury: A relative's perspective, George P. Prigatano, Susan Borgaro, Jason Baker, and Jennifer Wethe

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Impaired self-awareness after moderately severe to severe traumatic brain injury, G. P. Prigatano

Quality of life in Essential Tremor Questionnaire (QUEST): development and initial validation, Alexander I. Tröster, Rajesh Pahwa, Julie A. Fields, Caroline M. Tanner, and Kelly E. Lyons

Action (verb) generation in HIV-1 infection, Steven Paul Woods, Catherine L. Carey, Alexander I. Tröster, and Igor Grant

Action (verb) fluency: test-retest reliability, normative standards, and construct validity, Steven Paul Woods, J Cobb Scott, Danielle A. Sires, Igor Grant, Robert K. Heaton, and Alexander I. Tröster

Submissions from 2004

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Disturbances in affective communication following brain injury, Susan R. Borgaro, George P. Prigatano, Christina Kwasnica, Sally Alcott, and Nancy Cutter

Neuropsychiatric complications of medical and surgical therapies for Parkinson's disease, David J. Burn and Alexander I. Tröster

Action verbal fluency normative data for the elderly, Andrea L. Piatt, Julie A. Fields, Anthony M. Paolo, and Alexander I. Tröster

Submissions from 2003

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Modification of the Patient Competency Rating Scale for use on an acute neurorehabilitation unit: The PCRS-NR, Susan R. Borgaro and George P. Prigatano

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The Patient Distress Scale questionnaire: Factor structure and internal consistency, Susan R. Borgaro, George P. Prigatano, Sally Alcott, Christina Kwasnica, and Nancy Cutter

Cognitive and affective sequelae in complicated and uncomplicated mild traumatic brain injury, Susan R. Borgaro, George P. Prigatano, Christina Kwasnica, and Jennie L. Rexer

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The youngest reported case of corticobasal degeneration, Anna DePold Hohler, Bruce R. Ransom, Michael R. Chun, Alexander I. Tröster, and Ali Samii

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Neuropsychological and quality of life outcomes 12 months after unilateral thalamic stimulation for essential tremor, J. A. Fields, A. I. Tröster, S. P. Woods, C. I. Higginson, S. B. Wilkinson, K. E. Lyons, W. C. Koller, and R. Pahwa

Challenging dogma in neuropsychology and related disciplines, George P. Prigatano

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Non-pharmacological management of psychiatric disturbances after traumatic brain injury, George P. Prigatano, Susan Borgaro, and Heather Caples

Qualitative features of finger movement during the Halstead finger oscillation test following traumatic brain injury, George P. Prigatano and Susan R. Borgaro

The three vectors of consciousness and their disturbances after brain injury, George P. Prigatano and Sterling C. Johnson

What do brain dysfunctional patients report following memory compensation training?, George P. Prigatano and Susan Kime

Effect of motor improvement on quality of life following subthalamic stimulation is mediated by changes in depressive symptomatology, Alexander I. Tröster, Julie A. Fields, Steven Wilkinson, Rajesh Pahwa, William C. Koller, and Kelly E. Lyons

Verbal fluency declines after pallidotomy: an interaction between task and lesion laterality, Alexander I. Tröster, Steven Paul Woods, and Julie A. Fields

Pulse width is associated with cognitive decline after thalamic stimulation for essential tremor, Steven Paul Woods, Julie A. Fields, Kelly E. Lyons, Rajesh Pahwa, and Alexander I. Tröster

Prodromal frontal/executive dysfunction predicts incident dementia in Parkinson's disease, Steven Paul Woods and Alexander I. Tröster

Submissions from 2002

Early cognitive and affective sequelae of traumatic brain injury: a study using the BNI Screen for Higher Cerebral Functions, Susan R. Borgaro and George P. Prigatano

Neural correlates of self-reflection., Sterling C Johnson, Leslie C Baxter, Lana S Wilder, James G Pipe, Joseph E Heiserman, and George P Prigatano

Long-term efficacy of globus pallidus stimulation for the treatment of Parkinson's disease, Kelly E. Lyons, Steven B. Wilkinson, Alexander I. Tröster, and Rajesh Pahwa

Effects of depression and Parkinson's disease on cognitive functioning, Suzanne Norman, Alexander I. Tröster, Julie A. Fields, and Rebecca Brooks

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Psychological factors in the genesis and management of nonepileptic seizures: Clinical observations, George P. Prigatano, Cynthia M. Stonnington, and Robert S. Fisher

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Neuropsychological deficits in essential tremor: An expression of cerebello-thalamo-cortical pathophysiology?, A. I. Tröster, S. P. Woods, J. A. Fields, K. E. Lyons, R. Pahwa, C. I. Higginson, and W. C. Koller

Declines in switching underlie verbal fluency changes after unilateral pallidal surgery in Parkinson's disease, Alexander I. Tröster, Steven Paul Woods, Julie A. Fields, Charlotte Hanisch, and William W. Beatty

Neuropsychological sequelae of subthalamic nucleus deep brain stimulation in Parkinson's disease: a critical review, Steven Paul Woods, Julie A. Fields, and Alexander I. Tröster

Submissions from 2001

Which symptoms of anxiety diminish after surgical interventions for Parkinson disease?, C. I. Higginson, J. A. Fields, and A. I. Tröster

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Long-term safety and efficacy of unilateral deep brain stimulation of the thalamus in essential tremor, William C. Koller, Kelly E. Lyons, Steven B. Wilkinson, Alexander I. Troster, and Rajesh Pahwa

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Comparison of thalamotomy to deep brain stimulation of the thalamus in essential tremor, Rajesh Pahwa, Kelly E. Lyons, Steven B. Wilkinson, Alexander I. Tröster, John Overman, Jennifer Kieltyka, and William C. Koller

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Neuropsychological and quality of life changes following unilateral thalamic deep brain stimulation in Parkinson's disease: A one-year follow-up, S. P. Woods, J. A. Fields, K. E. Lyons, W. C. Koller, S. B. Wilkinson, R. Pahwa, and A. I. Tröster

Submissions from 2000

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Cognitive outcomes after deep brain stimulation for Parkinson's disease: A review of initial studies and recommendations for future research, Julie A. Fields and Alexander I. Tröster

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Effect and time course of deep brain stimulation of the globus pallidus and subthalamus on motor features of Parkinson's disease, Anna Hristova, Kelly Lyons, Alexander I. Tröster, Rajesh Pahwa, Steven B. Wilkinson, and William C. Koller