Neuropsychological and quality of life changes following unilateral thalamic deep brain stimulation in Parkinson's disease: A one-year follow-up
Document Type
Article
Abstract
Background. The long-term neuropsychological and quality of life (QOL) outcomes of unilateral thalamic deep brain stimulation (DBS) in patients with intractable Parkinson's disease (PD) have not heretofore been described. Method. Six patients diagnosed with PD underwent unilateral DBS implantation into a veri(r)ed thalamic VIM nucleus target. Participants completed presurgical neuropsychological evaluation and follow-up assessment at approximately one year postsurgery. Findings. Compared to their presurgical scores, PD patients exhibited signi(r)cant improvement on measures of conceptualization, verbal memory, emotional adjustment, and QOL at one-year follow-up. A few nominal declines were observed across the battery of tests. Interpretation. These data provide preliminary support for the long-term neurocognitive safety and QOL improvements following thalamic stimulation in patients with PD.
Publication Date
12-1-2001
Publication Title
Acta Neurochirurgica
ISSN
00016268
Volume
143
Issue
12
First Page
1273
Last Page
1278
PubMed ID
11810392
Digital Object Identifier (DOI)
10.1007/s007010100024
Recommended Citation
Woods, S. P.; Fields, J. A.; Lyons, K. E.; Koller, W. C.; Wilkinson, S. B.; Pahwa, R.; and Tröster, A. I., "Neuropsychological and quality of life changes following unilateral thalamic deep brain stimulation in Parkinson's disease: A one-year follow-up" (2001). Clinical Neuropsychology. 94.
https://scholar.barrowneuro.org/neuropsychology/94