A Précis of recent advances in the neuropsychology of mild cognitive impairment(s) in Parkinson's disease and a proposal of preliminary research criteria

Document Type

Article

Abstract

Cognitive changes of Parkinson's disease (PD) manifest earlier and are more heterogeneous than previously appreciated. Approximately one-third of patients have at least mild cognitive changes at PD diagnosis, and subtle changes might be appreciable among those at risk for PD. Executive dysfunction is the most common cognitive change, but other phenotypes exist. Pathobiologic and potential prognostic differences among cognitive phenotypes remain poorly understood. Progress in the neuropsychology, epidemiology and pathobiology of mild cognitive impairment (MCI) in PD is hampered by lack of diagnostic criteria. This study proposes preliminary research criteria for two categories of PD non-dementia cognitive impairment. © 2011 The International Neuropsychological Society.

Publication Date

5-1-2011

Publication Title

Journal of the International Neuropsychological Society

ISSN

13556177

E-ISSN

14697661

Volume

17

Issue

3

First Page

393

Last Page

406

PubMed ID

21473805

Digital Object Identifier (DOI)

10.1017/S1355617711000257

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