The Barrow Neurological Institute is proud of its reputation as a medical research facility and is home to some of the most sophisticated research programs outside of an academic setting in the Southwestern United States. Researchers in the Barrow Neurosurgery Research Center are devoted to learning more about the causes of and treatments for a wide range of disorders, such as stroke, aneurysms, spinal cord injury, and hydrocephalus. Our research has led to treatments that are being used around the world. Within the Department are neurosurgeons who subspecialize in cerebrovascular and skull base, functional and stereotactic, pediatric, spine, tumor, and endovascular neurosurgery.

Physicians, scientists, and expert clinical staff come together with a commitment to developing new techniques for the prevention, diagnosis, treatment, and rehabilitation of neurological illnesses and injuries. The leadership of internationally respected physicians keeps Barrow at the forefront of neuroscience. The compassionate expertise of its extensive staff of nurses, technologists, therapists and support personnel is evident in every aspect of care provided.

Our mission is to advance the knowledge and practice of medicine in neuroscience through basic and clinical research, education of medical professionals, and innovation in clinical techniques and technology.

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Submissions from 2023

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Mechanistic insights on age-related changes in heart-aorta-brain hemodynamic coupling using a pulse wave model of the entire circulatory system, Arian Aghilinejad, Faisal Amlani, Sohrab P. Mazandarani, Kevin S. King, and Niema M. Pahlevan

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MRI Imaging Appearance of Hyperostosis Frontalis Interna (HFI): A Case Report of Focal Benign Enhancement, Anish Bhandari, Mark Greenhill, Mayra Anthony, Sorabh Sharma, and Raza Mushtaq

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"Best of" ASNR 2023 (Chicago) and "Sneak Peek" of ASNR 2024 (Las Vegas), Paul M. Bunch, Birgit B. Ertl-Wagner, Wende N. Gibbs, Steven Lev, and Michael H. Lev

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Management Algorithm for Osseous Metastatic Disease: What the Treatment Teams Want to Know, Wende N. Gibbs, Mahmud Mossa Basha, and J Levi Chazen

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Osteoradionecrosis of the Skull Base in Nasopharyngeal Carcinoma, Mark J. Greenhill, Shanen P. Jean, Gabriel Duhancioglu, Christopher H. Le, and Raza Mushtaq

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Thromboembolic Disorder in COVID-19 Infection, Shawn Lee, Joseph Gunderson, and Raza Mushtaq

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Diffuse mass-like dural-based neurosarcoidosis with concurrent leptomeningeal involvement: an unusual case presentation and review, Zachary Morrison, Mary Y. Yeh, and Jeremy Hughes

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Spectrum of injuries with "less-lethal" beanbag weapons: pictorial essay, Damon Salar Motamedi, Zachary Todd Fitzgerald, Berndt Schmit, and Raza Mushtaq

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Reducing annotation burden in MR: A novel MR-contrast guided contrastive learning approach for image segmentation, Lavanya Umapathy, Taylor Brown, Raza Mushtaq, Mark Greenhill, J'rick Lu, Diego Martin, Maria Altbach, and Ali Bilgin

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Surveillance imaging strategies for pituitary adenomas: when, how frequent and when to stop, Kevin C. Yuen, Luma Ghalib, Michael Buchfelder, Jeremy Hughes, Fabienne Langlois, and Mark E. Molitch

Submissions from 2022

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Incidence and clinical significance of epidural fluid signal on spinal magnetic resonance imaging after image-guided lumbar puncture in adults, Eric M. Christiansen, Paul Kang, and Jeremy N. Hughes

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Evolution of postoperative pituitary adenoma resection cavities assessed by magnetic resonance imaging and implications regarding radiotherapy timing and modality, Michael T. Farnworth, Kevin C. Yuen, Kristina M. Chapple, Nicholas G. Matthees, William L. White, Andrew S. Little, Leland Rogers, and Jeremy N. Hughes

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Multispecialty perspective on intradural disc herniation: diagnosis and management - A case report, Vinicius Tieppo Francio, Christopher S. Wie, Micheal T. Murphy, Matthew T. Neal, Mark K. Lyons, Wende N. Gibbs, and Natalie H. Strand

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Podcasts: Enhancing Education in a Digital World, Ross P. Frederick and Wende N. Gibbs

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Vascular risk profile and white matter hyperintensity volume among Mexican Americans and non-Hispanic Whites: The HABLE study, Kevin S. King, Raul M. Vintimilla, Meredith N. Braskie, Ke Wei, James R. Hall, Matt Borzage, Leigh A. Johnson, Kristine Yaffe, Arthur W. Toga, and Sid E. O'Bryant

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Atlantoaxial Osteoarthritis: A Well-Established Entity that Remains Frequently Overlooked, Matthew T. Neal, Wende Gibbs, and Mark K. Lyons

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Utility of Virtual Spine Neurosurgery Education for Medical Students, Nathan A. Shlobin, Ryan E. Radwanski, Michael W. Kortz, Jonathan J. Rasouli, Wende N. Gibbs, Khoi D. Than, Ali A. Baaj, John H. Shin, and Nader S. Dahdaleh

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Assessment of cervical spinal cord volume in pediatric-onset multiple sclerosis, Saher Suleman, Matthew Harwood, Paul Kang, Ram Narayan, and Jeremy N. Hughes

Submissions from 2021

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Anti-NMDA receptor encephalitis and brain atrophy in children and adults: A quantitative study, Frederick C. Bassal, Matthew Harwood, Ann Oh, Jaclyn N. Lundberg, Justin Hoffman, Patricia Cornejo, Kristina M. Chapple, Jeremy N. Hughes, and Ram Narayan

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The Prognostic Role of Magnetic Resonance Imaging Biomarkers in Mild Traumatic Injury, Elie Massaad, John H. Shin, and Wende N. Gibbs

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Artificial Intelligence and Robotics in Spine Surgery, Jonathan J. Rasouli, Jianning Shao, Sean Neifert, Wende N. Gibbs, Ghaith Habboub, Michael P. Steinmetz, Edward Benzel, and Thomas E. Mroz

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Role of magnetic resonance imaging in Bouveret's syndrome: A case report with review of the literature, Irina Sadovnikov, Michelle Anthony, Raza Mushtaq, Mohammad Khreiss, Hemanth Gavini, and Hina Arif-Tiwari

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Algorithms for segmenting cerebral time-of-flight magnetic resonance angiograms from volunteers and anemic patients, Alexander Saunders, Kevin S. King, Stefan Blüml, John C. Wood, and Matthew Borzage

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Performance of overnight on-call radiology residents in interpreting unenhanced abdominopelvic magnetic resonance imaging studies performed for pediatric right lower quadrant abdominal pain, David M. Sawyer, Raza Mushtaq, Srinivasan Vedantham, Faryal Shareef, Sara M. Desoky, Hina Arif-Tiwari, Dorothy L. Gilbertson-Dahdal, and Unni K. Udayasankar

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Regional relationships between CSF VEGF levels and Alzheimer's disease brain biomarkers and cognition, Meral A. Tubi, Deydeep Kothapalli, Matthew Hapenney, Franklin W. Feingold, Wendy J. Mack, Kevin S. King, Paul M. Thompson, and Meredith N. Braskie

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MRI Automated T1 Signal Intensity Detection of Diffuse Brain Manganese Accumulation in Cirrhosis, Ke Wei, Thao T. Tran, Patrick W. Chang, Annie Malekie, Karen Chu, Lea Alhilali, Matthew T. Borzage, Edward Mena, Michael G. Harrington, and Kevin S. King

Submissions from 2020

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Dynamic Effects of Aortic Arch Stiffening on Pulsatile Energy Transmission to Cerebral Vasculature as A Determinant of Brain-Heart Coupling, Arian Aghilinejad, Faisal Amlani, Kevin S. King, and Niema M. Pahlevan

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Improved Assessment of Hypertensive Related Brain Insults in Late Life Using Central Pulse Pressure, Kevin S. King

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Pearls and Pitfalls of Quantitative Software Analysis of Dopamine Transporter SPECT, Raza Mushtaq, Matthew D. Kay, Laura Steinmeyer, Devdutta Warhadpande, and Phillip H. Kuo

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Group delay method for MRI aortic pulse wave velocity measurements in clinical protocols with low temporal resolution: Validation in a heterogeneous cohort, Niema M. Pahlevan, Timothy Yao, Karen Chu, Soren Cole, Thao Tran, John C. Wood, and Kevin S. King

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Common Data Elements in Head and Neck Radiology Reporting, Anandh G. Rajamohan, Vishal Patel, Nasim Sheikh-Bahaei, Chia-Shang J. Liu, John L. Go, Paul E. Kim, Wende Gibbs, and Jay Acharya

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Virtual Spine: A Novel, International Teleconferencing Program Developed to Increase the Accessibility of Spine Education During the COVID-19 Pandemic, Jonathan J. Rasouli, John H. Shin, Khoi D. Than, Wende N. Gibbs, Griffin R. Baum, and Ali A. Baaj

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Brain MR Spectroscopy Markers of Encephalopathy Due to Nonalcoholic Steatohepatitis, Thao T. Tran, Ke Wei, Soren Cole, Edward Mena, Marie Csete, and Kevin S. King

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White matter hyperintensities and their relationship to cognition: Effects of segmentation algorithm, Meral A. Tubi, Franklin W. Feingold, Deydeep Kothapalli, Evan T. Hare, Kevin S. King, Paul M. Thompson, and Meredith N. Braskie

Submissions from 2019

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Alpha desynchronization during simple working memory unmasks pathological aging in cognitively healthy individuals, Xianghong Arakaki, Ryan Lee, Kevin S. King, Alfred N. Fonteh, and Michael G. Harrington

Subject-Specific Studies of CSF Bulk Flow Patterns in the Spinal Canal: Implications for the Dispersion of Solute Particles in Intrathecal Drug Delivery., W Coenen, C Gutiérrez-Montes, S Sincomb, E Criado-Hidalgo, K Wei, Kevin S. King, V Haughton, C Martínez-Bazán, A L Sánchez, and J C Lasheras

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Spine Oncology: Imaging and Intervention, Wende N. Gibbs, Kambiz Nael, Amish H. Doshi, and Lawrence N. Tanenbaum

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Sacral Fractures and Sacroplasty, Wende Nocton Gibbs and Amish Doshi

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Headache and Brain Tumor, Shahram Hadidchi, Wesley Surento, Alexander Lerner, Chia-Shang Jason Liu, Wende N. Gibbs, Paul E. Kim, and Mark S. Shiroishi

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Pneumomediastinum in blunt trauma: If aerodigestive injury is not seen on CT, invasive workup is not indicated, Nicholas G. Matthees, James A. Mankin, Amy M. Trahan, Sharjeel Israr, Michael D. Jones, Jonathan L. Dameworth, Scott R. Petersen, and Jordan A. Weinberg

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First-Line Diagnostic Evaluation with MRI of Children Suspected of Having Acute Appendicitis, Raza Mushtaq, Sarah M. Desoky, Frank Morello, Dorothy Gilbertson-Dahdal, Geetha Gopalakrishnan, Aaron Leetch, Srinivasan Vedantham, Bobby Kalb, Diego R. Martin, and Unni K. Udayasankar

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The Art of Interpreting Cervical Spine Radiographs, Matthew R. Skalski, George R. Matcuk, and Wende N. Gibbs

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White matter hypointensities and hyperintensities have equivalent correlations with age and CSF β-amyloid in the nondemented elderly, Ke Wei, Thao Tran, Karen Chu, Matthew T. Borzage, Meredith N. Braskie, Michael G. Harrington, and Kevin S. King

Submissions from 2018

Complications of Radiotherapy and Radiosurgery in the Brain and Spine., G Barisano, S Bergamaschi, J Acharya, A Rajamohan, Wende N. Gibbs, P Kim, G Zada, E Chang, and M Law

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A new MRI tag-based method to non-invasively visualize cerebrospinal fluid flow, Matthew Borzage, Skorn Ponrartana, Benita Tamrazi, Wende Gibbs, Marvin D. Nelson, J Gordon McComb, and Stefan Blüml

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Conventional and Advanced Imaging of Spine Oncologic Disease, Nonoperative Post-treatment Effects, and Unique Spinal Conditions, Falgun H. Chokshi, Meng Law, and Wende N. Gibbs

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Distinguishing Brain Impact of Aging and HIV Severity in Chronic HIV Using Multiparametric MR Imaging and MR Spectroscopy, Karen Chu, Thao Tran, Ke Wei, Jeanne C. Lammering, Anders Sondergaard, Emad Mogadam, Kimberly Shriner, and Kevin S. King

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Detrimental effect of systemic vascular risk factors on brain hemodynamic function assessed with MRI, Kevin S. King, Min Sheng, Peiying Liu, Christopher D. Maroules, Craig D. Rubin, Ron M. Peshock, Roderick W. McColl, and Hanzhang Lu

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No-reflow phenomenon in the heart and brain, Robert A. Kloner, Kevin S. King, and Michael G. Harrington

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Diffuse periostitis as the primary presenting radiological finding in an AML patient with disease relapse, Raza Mushtaq, David Nolte, Faryal Shareef, and Mihra S. Taljanovic

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Imaging of Spondylolysis: The Evolving Role of Magnetic Resonance Imaging, Raza Mushtaq, Jack Porrino, and Gloria J. Guzmán Pérez-Carrillo

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Neural Foraminal Lesions: An Imaging Overview, Raza Mushtaq, Jack Porrino, Sylvestor A. Moses, and Gloria J. Guzmán Pérez-Carrillo

Submissions from 2017

CT Angiography of the Head in Extracorporeal Membrane Oxygenation., J Acharya, A G Rajamohan, M R Skalski, M Law, P Kim, and W Gibbs

Hippocampal volume in patients with asthma: Results from the Dallas Heart Study., Scott M Carlson, Julie Kim, David A Khan, Kevin S. King, Richard T Lucarelli, Roderick McColl, Ronald Peshock, and E Sherwood Brown

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Ethnic Difference in Proximal Aortic Stiffness: An Observation From the Dallas Heart Study, Akshay Goel, Christopher D. Maroules, Gary F. Mitchell, Ronald Peshock, Colby Ayers, Roderick McColl, Wanpen Vongpatanasin, and Kevin S. King

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Heart Failure-Induced Brain Injury, Ofer Havakuk, Kevin S. King, Luanda Grazette, Andrew J. Yoon, Michael Fong, Noa Bregman, Uri Elkayam, and Robert A. Kloner

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EEG fluctuations of wake and sleep in mild cognitive impairment, Johnny O'Keeffe, Barbara Carlson, Lisa DeStefano, Michael Wenger, Melissa Craft, Linda Hershey, Jeremy Hughes, Dee Wu, Lei Ding, and Han Yuan

Submissions from 2016

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Correction and optimization of a T2-based approach to map blood oxygenation in small cerebral veins, Lisa C. Krishnamurthy, Deng Mao, Kevin S. King, and Hanzhang Lu

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Relationship between leukoaraiosis, carotid intima-media thickness and intima-media thickness variability: Preliminary results, Pierleone Lucatelli, Eytan Raz, Luca Saba, Giovanni Maria Argiolas, Roberto Montisci, Max Wintermark, Kevin S. King, Filippo Molinari, Nobutaka Ikeda, Paolo Siotto, and Jasjit S. Suri

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Predicting Meningioma Consistency on Preoperative Neuroimaging Studies, Mark S. Shiroishi, Steven Y. Cen, Benita Tamrazi, Francesco D'Amore, Alexander Lerner, Kevin S. King, Paul E. Kim, Meng Law, Darryl H. Hwang, Orest B. Boyko, and Chia-Shang J. Liu

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Cardiovascular Risk Factors Associated with Smaller Brain Volumes in Regions Identified as Early Predictors of Cognitive Decline, Rajiv N. Srinivasa, Heidi C. Rossetti, Mohit K. Gupta, Roger N. Rosenberg, Myron F. Weiner, Ronald M. Peshock, Roderick W. McColl, Linda S. Hynan, Richard T. Lucarelli, and Kevin S. King

Submissions from 2015

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The effects of SENSE on PROPELLER imaging, Yuchou Chang, James G. Pipe, John P. Karis, Wende N. Gibbs, Nicholas R. Zwart, and Michael Schär

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Association of 3.0-T brain magnetic resonance imaging biomarkers with cognitive function in the Dallas Heart Study, Mohit Gupta, Kevin S. King, Rajiv Srinivasa, Myron F. Weiner, Keith Hulsey, Colby R. Ayers, Anthony Whittemore, Roderick W. McColl, Heidi C. Rossetti, and Ronald M. Peshock

Connected Care Is Essential to Telemedicine's Success, Alan Pitt

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Cognitive impact of lacunar infarcts and white matter hyperintensity volume, Matthew W. Warren, Myron F. Weiner, Heidi C. Rossetti, Roderick McColl, Ron Peshock, and Kevin S. King

Submissions from 2014

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Association of depressive symptoms with hippocampal volume in 1936 adults, E Sherwood Brown, Carroll W. Hughes, Roderick McColl, Ronald Peshock, Kevin S. King, and A John Rush

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Fully automated tool to identify the aorta and compute flow using phase-contrast MRI: validation and application in a large population based study, Akshay Goel, Roderick McColl, Kevin S. King, Anthony Whittemore, and Ronald M. Peshock

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Arterial stiffness as a potential determinant of β-amyloid deposition, Kevin S. King

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Effect of leukocyte telomere length on total and regional brain volumes in a large population-based cohort, Kevin S. King, Julia Kozlitina, Roger N. Rosenberg, Ronald M. Peshock, Roderick W. McColl, and Christine K. Garcia

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Effect of normal aging versus hypertension, abnormal body mass index, and diabetes mellitus on white matter hyperintensity volume, Kevin S. King, Ronald M. Peshock, Heidi C. Rossetti, Roderick W. McColl, Colby R. Ayers, Keith M. Hulsey, and Sandeep R. Das

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Cardiovascular outcome associations among cardiovascular magnetic resonance measures of arterial stiffness: the Dallas heart study, Christopher D. Maroules, Amit Khera, Colby Ayers, Akshay Goel, Ronald M. Peshock, Suhny Abbara, and Kevin S. King

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Revised motion estimation algorithm for PROPELLER MRI, James G. Pipe, Wende N. Gibbs, Zhiqiang Li, John P. Karis, Michael Schar, and Nicholas R. Zwart

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What do we mean by value?, Alan Pitt

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Genetic, anatomic, and clinical determinants of human serum sterol and vitamin D levels, Ashlee R. Stiles, Julia Kozlitina, Bonne M. Thompson, Jeffrey G. McDonald, Kevin S. King, and David W. Russell

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Urinary albumin to creatinine ratio as potential biomarker for cerebral microvascular disease, Amanda L. Strickland, Heidi C. Rossetti, Ronald M. Peshock, Myron F. Weiner, Paul A. Nakonezny, Roderick W. McColl, Keith M. Hulsey, Sandeep R. Das, and Kevin S. King

Submissions from 2013

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White matter hyperintensities: use of aortic arch pulse wave velocity to predict volume independent of other cardiovascular risk factors, Kevin S. King, Ke Xun Chen, Keith M. Hulsey, Roderick W. McColl, Myron F. Weiner, Paul A. Nakonezny, and Ronald M. Peshock

MR imaging of hippocampal asymmetry at 3T in a multiethnic, population-based sample: results from the Dallas Heart Study., R T Lucarelli, R M Peshock, R McColl, K Hulsey, C Ayers, A R Whittemore, and K S King

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A rare opportunity for conservative treatment in a case of blunt trauma to the supradiaphragmatic inferior vena cava, Nicholas G. Matthees, James A. Mankin, Olga M. Kalinkin, and Randy R. Richardson

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Physiologic underpinnings of negative BOLD cerebrovascular reactivity in brain ventricles, Binu P. Thomas, Peiying Liu, Sina Aslan, Kevin S. King, Matthias J. van Osch, and Hanzhang Lu

Submissions from 2012

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AIRP best cases in radiologic-pathologic correlation: cerebral fat embolism syndrome in sickle cell β-thalassemia, Wende N. Gibbs, Michael J. Opatowsky, and Elizabeth C. Burton

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Automated quantification of white matter disease extent at 3 T: comparison with volumetric readings, Keith M. Hulsey, Mohit Gupta, Kevin S. King, Ronald M. Peshock, Anthony R. Whittemore, and Roderick W. McColl

Submissions from 2008

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Bilateral lymphadenopathy in a young woman, Wende N. Gibbs, Debbie A. Bridges, and Michael J. Opatowsky

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Diagnosis of congenital unicuspid aortic valve by 64-slice cardiac computed tomography, Wende N. Gibbs, Baron L. Hamman, William C. Roberts, and Jeffrey M. Schussler

Submissions from 2006

Pituicytoma: diagnostic features on selective carotid angiography and MR imaging., W N Gibbs, E S Monuki, M E Linskey, and A N Hasso

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Evaluation of a novel EEG preamplifier, Arthur C. Grant, James P. O'Halloran, Steve S. Chung, Wende Gibbs, and Peter W. Kaplan

Submissions from 2005

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Acute hemorrhagic leukoencephalitis: neuroimaging features and neuropathologic diagnosis, Wende N. Gibbs, Mahmoud A. Kreidie, Ronald C. Kim, and Anton N. Hasso

Submissions from 2004

Charcot-Marie-Tooth disease: extensive cranial nerve involvement on CT and MR imaging, Todd R. Aho, Robert C. Wallace, Alan M. Pitt, and Kumaraswamy Sivakumar

Submissions from 2003

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A microRNA array reveals extensive regulation of microRNAs during brain development, Anna M. Krichevsky, Kevin S. King, Christine P. Donahue, Konstantin Khrapko, and Kenneth S. Kosik

Submissions from 2000

Effect of voxel position on single-voxel MR spectroscopy findings., P E Ricci, A Pitt, P J Keller, S W Coons, and J E Heiserman

Submissions from 1996

Discontinuation of antiepileptic drug treatment after two seizure-free years in children with cerebral palsy., M R Delgado, A R Riela, J Mills, A Pitt, and R Browne

Submissions from 1993

MRI-guided biopsy in inflammatory myopathy: initial results., A M Pitt, J L Fleckenstein, R G Greenlee, D K Burns, W W Bryan, and R Haller

Submissions from 1988

Drosophila homolog of the murine Int-1 protooncogene., E Uzvölgyi, I Kiss, A Pitt, S Arsenian, S Ingvarsson, A Udvardy, M Hamada, G Klein, and J Sümegi