The Barrow Neurological Institute is proud of its reputation as a medical research facility and is home to some of the most sophisticated research programs outside of an academic setting in the Southwestern United States. Researchers in the Barrow Neurosurgery Research Center are devoted to learning more about the causes of and treatments for a wide range of disorders, such as stroke, aneurysms, spinal cord injury, and hydrocephalus. Our research has led to treatments that are being used around the world. Within the Department are neurosurgeons who subspecialize in cerebrovascular and skull base, functional and stereotactic, pediatric, spine, tumor, and endovascular neurosurgery.

Physicians, scientists, and expert clinical staff come together with a commitment to developing new techniques for the prevention, diagnosis, treatment, and rehabilitation of neurological illnesses and injuries. The leadership of internationally respected physicians keeps Barrow at the forefront of neuroscience. The compassionate expertise of its extensive staff of nurses, technologists, therapists and support personnel is evident in every aspect of care provided.

Our mission is to advance the knowledge and practice of medicine in neuroscience through basic and clinical research, education of medical professionals, and innovation in clinical techniques and technology.

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Submissions from 2024

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Amniotic Membrane Augmentation for Enucleation After Chemotherapy in Retinoblastoma, Aparna Ramasubramanian, Nisha S. Rehman, Argudit Chauhan, Aurora Rodriguez, Amy Leverant, and Nishant Tiwari

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Three-Dimensional Ultrasound Imaging of Retinoblastoma and Its Correlation With Pathology, Aparna Ramasubramanian, Monique Riemann, Alex Brown, Alyson Tukan, Nishant Tiwari, Todd Abruzzo, and Luis F. Goncalves

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Ciliary Body Perivascular Epithelioid Cell Tumor, Katie Simms, Nishant Tiwari, and Aparna Ramasubramanian

Submissions from 2023

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BRAF Immunohistochemical Studies of Pediatric Conjunctival Lesions, Kelsey Chen, Kerri McInnis-Smith, Nishant Tiwari, Justin C. Moser, and Aparna Ramasubramanian

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Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy-Associated Hepatitis, Zhubene Mesbah, Nishant Tiwari, and Keith Sacco

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Epithelioid neoplasm of the spinal cord in a child with spinal muscular atrophy treated with onasemnogene abeparvovec, Laura Retson, Nishant Tiwari, Jennifer Vaughn, Saunder Bernes, P David Adelson, Keith Mansfield, Silvana Libertini, Brent Kuzmiski, Iulian Alecu, Richard Gabriel, and Ross Mangum

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Orbital cellulitis with panophthalmitis and scleral necrosis - a case report, Aurora Rodriguez, Kamran Ahmed, Nishant Tiwari, and Aparna Ramasubramanian

Submissions from 2022

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Diagnostic and Prognostic Implications of GNAS Inactivation in Sonic Hedgehog-Activated Medulloblastoma: Case Report with Comprehensive Molecular Profiling and Review of Literature, Erin Goode, Liliana Montoya, Eric Graham, Brianna Pruniski, Curtis Simmons, Alexander Ngwube, Lindsey M. Hoffman, Nishant Tiwari, Kenneth Aldape, Harper N. Price, Vera Paulson, and Ross Mangum

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ALK-positive histiocytosis: a new clinicopathologic spectrum highlighting neurologic involvement and responses to ALK inhibition, Paul G. Kemps, Jennifer Picarsic, Benjamin H. Durham, Zofia Hélias-Rodzewicz, Laura Hiemcke-Jiwa, Cor van den Bos, Marianne D. van de Wetering, Carel J. van Noesel, Jan A. van Laar, Robert M. Verdijk, Uta E. Flucke, Pancras C. Hogendoorn, F J. Woei-A-Jin, Raf Sciot, Andreas Beilken, Friedrich Feuerhake, Martin Ebinger, Robert Möhle, Falko Fend, Antje Bornemann, Verena Wiegering, Karen Ernestus, Tina Méry, Olga Gryniewicz-Kwiatkowska, Bozenna Dembowska-Baginska, Dmitry A. Evseev, Vsevolod Potapenko, Vadim V. Baykov, Stefania Gaspari, Sabrina Rossi, and Marco Gessi

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PLAG1 Immunohistochemical Staining Is a Surrogate Marker for Fusions in Lipoblastomas, Mikako Warren, Nishant Tiwari, Sabrina Sy, Gordana Raca, Ryan J. Schmidt, and Bruce Pawel

Submissions from 2021

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Clinicopathologic Characteristics of Late Acute Antibody-mediated Rejection in Pediatric Liver Transplantation, Shengmei Zhou, Tania Mitsinikos, Juliet Emamaullee, Carly Weaver, Larry Wang, Nick Shillingford, Mikako Warren, Julie Huss Bawab, Nishant Tiwari, Yuri Genyk, Danny Thomas, and David M. Parham

Submissions from 2020

C3a receptor antagonist therapy is protective with or without thrombolysis in murine thromboembolic stroke., Saif Ahmad, Chirayu Pandya, Adam Kindelin, Kanchan Bhatia, Rafay Chaudhary, Alok Kumar Dwivedi, Jennifer M Eschbacher, Qiang Liu, Michael F Waters, Md Nasrul Hoda, and Andrew F. Ducruet

Using the Post-Descendens Hypoglossal Nerve in Hypoglossal-Facial Anastomosis: An Anatomic and Histologic Feasibility Study., Ali Tayebi Meybodi, Leandro Borba Moreira, Xiaochun Zhao, Evgenii Belykh, Michael T. Lawton, Jennifer M Eschbacher, and Mark C Preul

Submissions from 2019

Clinical, pathologic, and imaging characteristics of pituitary null cell adenomas as defined according to the 2017 World Health Organization criteria: a case series from two pituitary centers., Joao Paulo Almeida, Corbin C Stephens, Jennifer M Eschbacher, Michelle M Felicella, Kevin C J Yuen, William L White, Michael A Mooney, Anne Laure Bernat, Ozgur Mete, Gelareh Zadeh, Fred Gentili, and Andrew S Little

Temporal Horn Choroid Plexus Papilloma Presenting with Seizures in Adulthood: Clinical Case Report and Review of the Literature., Tsinsue Chen, George M Mastorakos, Kyle I Swanson, Jennifer M Eschbacher, and Kris A Smith

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Berunda Polypeptides: Biheaded Rapamycin Carriers for Subcutaneous Treatment of Autoimmune Dry Eye Disease, Changrim Lee, Hao Guo, Wannita Klinngam, Srikanth R. Janga, Frances Yarber, Santosh Peddi, Maria C. Edman, Nishant Tiwari, Siyu Liu, Stan G. Louie, Sarah F. Hamm-Alvarez, and J Andrew MacKay

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Unusual radiological and histological presentation of a diffuse leptomeningeal glioneuronal tumor (DLGNT) in a 13-year-old girl, Nishant Tiwari, Benita Tamrazi, Nathan Robison, Mark Krieger, Jianling Ji, and Di Tian

Submissions from 2017

Radiogenomics To Characterize Regional Genetic Heterogeneity In Glioblastoma, Leland S. Hu, Shuluo Ning, Jennifer M Eschbacher, Leslie C. Baxter, Nathan Gaw, Sara Ranjbar, Jonathan Plasencia, Amylou C. Dueck, Sen Peng, Kris A Smith, Peter Nakaji, John P Karis, C. Chad Quarles, Teresa Wu, Joseph C. Loftus, Robert B. Jenkins, Hugues Sicotte, Thomas M. Kollmeyer, Brian P. O'Neill, William Elmquist, Joseph M. Hoxworth, David Frakes, Jann Sarkaria, Kristin R. Swanson, Nhan L. Tran, Jing Li, and J. Ross Mitchell

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Palliative Care Options for a Young Adult Patient with a Diffuse Intrinsic Pontine Glioma, Julian Sison, Hung Tran, Ashley Margol, Nishant Tiwari, Karla M. Garcia, Jennifer Cotter, Erin Kiehna, Arthur J. Olch, and Kenneth Wong

Submissions from 2015

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Multi-Parametric MRI and Texture Analysis to Visualize Spatial Histologic Heterogeneity and Tumor Extent in Glioblastoma., Leland S Hu, Shuluo Ning, Jennifer M Eschbacher, Nathan Gaw, Amylou C Dueck, Kris A Smith, Peter Nakaji, Jonathan Plasencia, Sara Ranjbar, Stephen J Price, Nhan Tran, Joseph Loftus, Robert Jenkins, Brian P O'Neill, William Elmquist, Leslie C Baxter, Fei Gao, David Frakes, John P Karis, Christine Zwart, Kristin R Swanson, Jann Sarkaria, Teresa Wu, J Ross Mitchell, and Jing Li

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Recurrent subependymoma of fourth ventricle with unusual atypical histological features: A case report, Nishant Tiwari, Suzanne Z. Powell, and Hidehiro Takei

Submissions from 2012

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Reevaluating the imaging definition of tumor progression: perfusion MRI quantifies recurrent glioblastoma tumor fraction, pseudoprogression, and radiation necrosis to predict survival., Leland S Hu, Jennifer M Eschbacher, Joseph E Heiserman, Amylou C Dueck, William R Shapiro, Seban Liu, John P Karis, Kris A Smith, Stephen W Coons, Peter Nakaji, Robert F Spetzler, Burt G Feuerstein, Josef Debbins, and Leslie C Baxter

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Regulation of CYP24 splicing by 1,25-dihydroxyvitamin D₃ in human colon cancer cells, Xinjian Peng, Nishant Tiwari, Sarbani Roy, Liang Yuan, Genoveva Murillo, Rajeshwari R. Mehta, Richard V. Benya, and Rajendra G. Mehta

Submissions from 2011

Intraoperative confocal microscopy for brain tumors: a feasibility analysis in humans., Nader Sanai, Jennifer M Eschbacher, Guido Hattendorf, Stephen W Coons, Mark C Preul, Kris A Smith, Peter Nakaji, and Robert F Spetzler

Submissions from 2010

Miniaturized handheld confocal microscopy for neurosurgery: results in an experimental glioblastoma model., Tejas Sankar, Peter M Delaney, Robert W Ryan, Jennifer M Eschbacher, Mohammed Abdelwahab, Peter Nakaji, Stephen W Coons, Adrienne C Scheck, Kris A Smith, Robert F Spetzler, and Mark C Preul