Recommendations of the Global Multiple System Atrophy Research Roadmap Meeting
Department
neurology
Document Type
Article
Abstract
Multiple system atrophy (MSA) is a rare neurodegenerative disorder with substantial knowledge gaps despite recent gains in basic and clinical research. In order to make further advances, concerted international collaboration is vital. In 2014, an international meeting involving leaders in the field and MSA advocacy groups was convened in Las Vegas, Nevada, to identify critical research areas where consensus and progress was needed to improve understanding, diagnosis, and treatment of the disease. Eight topic areas were defined: pathogenesis, preclinical modeling, target identification, endophenotyping, clinical measures, imaging biomarkers, nonimaging biomarkers, treatments/trial designs, and patient advocacy. For each topic area, an expert served as a working group chair and each working group developed priority-ranked research recommendations with associated timelines and pathways to reach the intended goals. In this report, each groups' recommendations are provided.
Medical Subject Headings
neurology
Publication Date
2018
Publication Title
Neurology
ISSN
0028-3878
Volume
90
Issue
2
First Page
74
Last Page
82
Digital Object Identifier (DOI)
10.1212/WNL.0000000000004798
Recommended Citation
Walsh, Ryan R.; Krismer, Florian; Galpern, Wendy R.; Wenning, Gregor K.; Low, Phillip A.; Halliday, Glenda; Koroshetz, Walter J.; Holton, Janice; Quinn, Niall P.; Rascol, Olivier; Shaw, Leslie M.; Eidelberg, David; Bower, Pam; Cummings, Jeffrey L.; Abler, Victor; Biedenharn, Judy; Bitan, Gal; Brooks, David J.; Brundin, Patrik; and al., et, "Recommendations of the Global Multiple System Atrophy Research Roadmap Meeting" (2018). Neurology. 287.
https://scholar.barrowneuro.org/neurology/287