Olfactory gyrus intracerebral hemorrhage in a patient with COVID-19 infection
Since the outbreak with novel corona virus in December 2019, a myriad of different neurological manifestations in patients with COVID-19 infection have been reported. We present a case of non-traumatic intracranial hemorrhage in the olfactory gyrus in a patient who tested positive for SARS-COV-2. The area of hemorrhage is not a common location for spontaneous hemorrhage. Given that loss of smell is considered a relatively common symptom of this pandemic, it is an intriguing association of COVID-19 and olfactory gyrus ICH for neurotropism of SARS-CoV2 for olfactory bulb and glia cells through nasal mucosa. Future studies will need to elucidate the exact mechanism of anosmia from COVID-19 and potential mechanisms leading to ICH.
Medical Subject Headings
Betacoronavirus; COVID-19; Cerebral Hemorrhage (diagnostic imaging, etiology); Coronavirus Infections (complications); Humans; Magnetic Resonance Imaging; Male; Middle Aged; Olfaction Disorders (etiology); Pandemics; Parietal Lobe (diagnostic imaging); Pneumonia, Viral (complications); SARS-CoV-2; Smell
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
Digital Object Identifier (DOI)
Thu, Sai Si; Matin, Nassim; and Levine, Steven R., "Olfactory gyrus intracerebral hemorrhage in a patient with COVID-19 infection" (2020). Neurology. 1515.