Olfactory gyrus intracerebral hemorrhage in a patient with COVID-19 infection

Authors

Sai Si Thu, Departments of Neurology, SUNY Downstate Health Sciences University, Brooklyn, NY, United States; Department of Neurology, Kings County Hospital Center, Brooklyn, NY, United States. Electronic address: saisi.thu@downstate.edu.
Nassim Matin, Departments of Neurology, SUNY Downstate Health Sciences University, Brooklyn, NY, United States; Department of Neurology, Kings County Hospital Center, Brooklyn, NY, United States.
Steven R. Levine, Departments of Neurology, SUNY Downstate Health Sciences University, Brooklyn, NY, United States; Emergency Medicine, SUNY Downstate Health Sciences University, Brooklyn, NY, United States; Department of Neurology, Kings County Hospital Center, Brooklyn, NY, United States. Electronic address: steven.levine@downstate.edu.

Document Type

Article

Abstract

Since the outbreak with novel corona virus in December 2019, a myriad of different neurological manifestations in patients with COVID-19 infection have been reported. We present a case of non-traumatic intracranial hemorrhage in the olfactory gyrus in a patient who tested positive for SARS-COV-2. The area of hemorrhage is not a common location for spontaneous hemorrhage. Given that loss of smell is considered a relatively common symptom of this pandemic, it is an intriguing association of COVID-19 and olfactory gyrus ICH for neurotropism of SARS-CoV2 for olfactory bulb and glia cells through nasal mucosa. Future studies will need to elucidate the exact mechanism of anosmia from COVID-19 and potential mechanisms leading to ICH.

Medical Subject Headings

Betacoronavirus; COVID-19; Cerebral Hemorrhage (diagnostic imaging, etiology); Coronavirus Infections (complications); Humans; Magnetic Resonance Imaging; Male; Middle Aged; Olfaction Disorders (etiology); Pandemics; Parietal Lobe (diagnostic imaging); Pneumonia, Viral (complications); SARS-CoV-2; Smell

Publication Date

9-1-2020

Publication Title

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

E-ISSN

1532-2653

Volume

79

First Page

275

Last Page

276

PubMed ID

33070912

Digital Object Identifier (DOI)

10.1016/j.jocn.2020.07.033

Recommended Citation

Thu, Sai Si; Matin, Nassim; and Levine, Steven R., "Olfactory gyrus intracerebral hemorrhage in a patient with COVID-19 infection" (2020). Neurology. 1515.
https://scholar.barrowneuro.org/neurology/1515