The Barrow Neurological Institute is proud of its reputation as a medical research facility and is home to some of the most sophisticated research programs outside of an academic setting in the Southwestern United States. Researchers in the Barrow Neurosurgery Research Center are devoted to learning more about the causes of and treatments for a wide range of disorders, such as stroke, aneurysms, spinal cord injury, and hydrocephalus. Our research has led to treatments that are being used around the world. Within the Department are neurosurgeons who subspecialize in cerebrovascular and skull base, functional and stereotactic, pediatric, spine, tumor, and endovascular neurosurgery.
Physicians, scientists, and expert clinical staff come together with a commitment to developing new techniques for the prevention, diagnosis, treatment, and rehabilitation of neurological illnesses and injuries. The leadership of internationally respected physicians keeps Barrow at the forefront of neuroscience. The compassionate expertise of its extensive staff of nurses, technologists, therapists and support personnel is evident in every aspect of care provided.
Our mission is to advance the knowledge and practice of medicine in neuroscience through basic and clinical research, education of medical professionals, and innovation in clinical techniques and technology.
Submissions from 2022
Evaluation of two-stage designs of Phase 2 single-arm trials in glioblastoma: a systematic review, Wonsuk Yoo, Seongho Kim, Michael Garcia, Shwetal Mehta, and Nader Sanai
Submissions from 2021
Dosimetric predictors of symptomatic radiation necrosis after five-fraction radiosurgery for brain metastases, Neal Andruska, William R. Kennedy, Liberty Bonestroo, Rebecca Anderson, Yi Huang, Clifford G. Robinson, Christopher Abraham, Christina Tsien, Nels Knutson, Keith M. Rich, Christopher Spencer, and Jiayi Huang
Internal dose escalation associated with increased local control for melanoma brain metastases treated with stereotactic radiosurgery, William R. Kennedy, Todd A. DeWees, Sahaja Acharya, Mustafaa Mahmood, Nels C. Knutson, S. Murty Goddu, James A. Kavanaugh, Timothy J. Mitchell, Keith M. Rich, Albert H. Kim, Eric C. Leuthardt, Joshua L. Dowling, Gavin P. Dunn, Michael R. Chicoine, Stephanie M. Perkins, Jiayi Huang, Christina I. Tsien, Clifford G. Robinson, and Christopher D. Abraham
Implementing Stereotactic Accelerated Partial Breast Irradiation using Magnetic Resonance Guided Radiation Therapy, Alex T. Price, William R. Kennedy, Lauren E. Henke, Sean R. Brown, Olga L. Green, Maria A. Thomas, and Imran Zoberi
Submissions from 2020
Prognostic Significance of Smoking in Human Papillomavirus–Positive Oropharyngeal Cancer Under American Joint Committee on Cancer Eighth Edition Stage, Smrithi Chidambaram, Erik R. Nakken, William Kennedy, Wade L. Thorstad, Stephanie Y. Chen, Patrik Pipkorn, Jose P. Zevallos, and Angela L. Mazul
Repeat stereotactic body radiation therapy (SBRT) for salvage of isolated local recurrence after definitive lung SBRT, William R. Kennedy, Prashant Gabani, John Nikitas, Clifford G. Robinson, Jeffrey D. Bradley, and Michael C. Roach
Long-Term Outcomes with 3-Dimensional Conformal External Beam Accelerated Partial Breast Irradiation, William R. Kennedy, Michael C. Roach, Maria A. Thomas, Laura Ochoa, Michael B. Altman, Leonel F. Hernandez-Aya, Amy E. Cyr, Julie A. Margenthaler, and Imran Zoberi
Impact of invasive nodal staging on regional and distant recurrence rates after SBRT for inoperable stage I NSCLC, William R. Kennedy, Pamela P. Samson, Prashant Gabani, John Nikitas, Jeffrey D. Bradley, Michael C. Roach, and Clifford G. Robinson
Single-Institution Phase 1/2 Prospective Clinical Trial of Single-Fraction, High-Gradient Adjuvant Partial-Breast Irradiation for Hormone Sensitive Stage 0-I Breast Cancer, William R. Kennedy, Maria A. Thomas, Jennifer A. Stanley, Jingqin Luo, Laura L. Ochoa, Katherine K. Clifton, Amy E. Cyr, Julie A. Margenthaler, Todd A. DeWees, Alex Price, Rojano Kashani, Olga Green, and Imran Zoberi
Predictors of distant metastases in triple-negative breast cancer without pathologic complete response after neoadjuvant chemotherapy, William R. Kennedy, Christopher Tricarico, Prashant Gabani, Ashley A. Weiner, Michael B. Altman, Laura L. Ochoa, Maria A. Thomas, Julie A. Margenthaler, Souzan Sanati, Lindsay L. Peterson, Cynthia X. Ma, Foluso O. Ademuyiwa, and Imran Zoberi
Intracranial Stereotactic Radiation Therapy With a Jawless Ring Gantry Linear Accelerator Equipped With New Dual Layer Multileaf Collimator, Nels C. Knutson, William R. Kennedy, Francisco J. Reynoso, Jiayuan Peng, Lauren E. Henke, Eric Laugeman, Michael Watts, Jessica Hillard, Ana Heermann, Geoffrey D. Hugo, Sasa Mutic, and Bin Cai
Stereotactic Radiosurgery to More Than 10 Brain Metastases: Evidence to Support the Role of Radiosurgery for Ideal Hippocampal Sparing in the Treatment of Multiple Brain Metastases, Matthew S. Susko, Michael A. Garcia, Lijun Ma, Jean L. Nakamura, David R. Raleigh, Shannon Fogh, Philip Theodosopoulos, Michael McDermott, Penny K. Sneed, and Steve E. Braunstein
Submissions from 2019
Treatment patterns of high-dose-rate and low-dose-rate brachytherapy as monotherapy for prostate cancer, Justin Barnes, William R. Kennedy, Benjamin W. Fischer-Valuck, Brian C. Baumann, Jeff M. Michalski, and Hiram A. Gay
Clinical outcomes and patterns of care in the treatment of carcinosarcoma of the breast, William R. Kennedy, Prashant Gabani, Sahaja Acharya, Maria A. Thomas, and Imran Zoberi
Treatment of T3N0 non-small cell lung cancer with chest wall invasion using stereotactic body radiotherapy, William R. Kennedy, Prashant Gabani, John Nikitas, Pamela P. Samson, Clifford G. Robinson, Jeffrey D. Bradley, and Michael C. Roach
Synthetic CT reconstruction using a deep spatial pyramid convolutional framework for MR-only breast radiotherapy, Sven Olberg, Hao Zhang, William R. Kennedy, Jaehee Chun, Vivian Rodriguez, Imran Zoberi, Maria A. Thomas, Jin Sung Kim, Sasa Mutic, Olga L. Green, and Justin C. Park
Palliative radiotherapy near the end of life, Susan Y. Wu, Lisa Singer, Lauren Boreta, Michael A. Garcia, Shannon E. Fogh, and Steve E. Braunstein
Palliative Oncologic Care Curricula for Providers in Resource-Limited and Underserved Communities: a Systematic Review, Melody J. Xu, David Su, Rebecca Deboer, Michael Garcia, Peggy Tahir, Wendy Anderson, Anne Kinderman, Steve Braunstein, and Tracy Sherertz
Submissions from 2018
Brain metastasis growth on preradiosurgical magnetic resonance imaging, Michael A. Garcia, Mekhail Anwar, Yao Yu, Sai Duriseti, Bryce Merritt, Jean Nakamura, Christopher Hess, Philip V. Theodosopoulos, Michael McDermott, Penny K. Sneed, and Steve E. Braunstein
Presenting Symptoms and Prognostic Factors for Symptomatic Outcomes Following Resection of Meningioma, Ashley Wu, Michael A. Garcia, Stephen T. Magill, William Chen, Harish N. Vasudevan, Arie Perry, Philip V. Theodosopoulos, Michael W. McDermott, Steve E. Braunstein, and David R. Raleigh
Submissions from 2017
Palliative Care Didactic Course for Radiation Oncology Residents, Michael A. Garcia, Steve E. Braunstein, and Wendy G. Anderson
Discovery of additional brain metastases on the day of stereotactic radiosurgery: Risk factors and outcomes, Michael A. Garcia, Ann Lazar, Sai Duriseti, David R. Raleigh, Christopher P. Hess, Shannon E. Fogh, Igor J. Barani, Jean L. Nakamura, David A. Larson, Philip Theodosopoulos, Michael McDermott, Penny K. Sneed, and Steve Braunstein
Neck Management with Total Laryngectomy and Adjuvant Radiotherapy in Locally Advanced Larynx Cancer, William R. Kennedy, Robert J. Amdur, Brian J. Boyce, Peter Dziegielewski, Christopher G. Morris, and William M. Mendenhall
Histopathologic review of pineal parenchymal tumors identifies novel morphologic subtypes and prognostic factors for outcome, David R. Raleigh, David A. Solomon, Shane A. Lloyd, Ann Lazar, Michael A. Garcia, Penny K. Sneed, Jennifer L. Clarke, Michael W. McDermott, Mitchel S. Berger, Tarik Tihan, and Daphne A. Haas-Kogan
Submissions from 2016
Exploiting molecular biology for diagnosis and targeted management of pediatric low-grade gliomas, Michael A. Garcia, David A. Solomon, and Daphne A. Haas-Kogan
Radiotherapy alone or combined with chemotherapy as definitive treatment for squamous cell carcinoma of the tonsil, William R. Kennedy, Michael P. Herman, Rohan L. Deraniyagala, Robert J. Amdur, John W. Werning, Peter Dziegielewski, Jessica Kirwan, Christopher G. Morris, and William M. Mendenhall
Ipsilateral radiotherapy for squamous cell carcinoma of the tonsil, William R. Kennedy, Michael P. Herman, Rohan L. Deraniyagala, Robert J. Amdur, John W. Werning, Peter T. Dziegielewski, Christopher G. Morris, and William M. Mendenhall
Treatment of ameloblastoma and ameloblastic carcinoma with radiotherapy, William R. Kennedy, John W. Werning, Frederic J. Kaye, and William M. Mendenhall
Submissions from 2014
Loss of function of TET2 cooperates with constitutively active KIT in murine and human models of mastocytosis., Serena De Vita, Rebekka K Schneider, Michael Garcia, Jenna Wood, Mathilde Gavillet, Benjamin L Ebert, Alexander Gerbaulet, Axel Roers, Ross L Levine, Ann Mullally, and David A Williams
Submissions from 2013
Diminazene attenuates pulmonary hypertension and improves angiogenic progenitor cell functions in experimental models, Vinayak Shenoy, Altin Gjymishka, Yagna P. Jarajapu, Yanfei Qi, Aqeela Afzal, Katya Rigatto, Anderson J. Ferreira, Rodrigo A. Fraga-Silva, Patrick Kearns, Jane Yellowlees Douglas, Deepmala Agarwal, Kamal K. Mubarak, Chastity Bradford, William R. Kennedy, Joo Y. Jun, Anandharajan Rathinasabapathy, Erin Bruce, Dipankar Gupta, Arturo J. Cardounel, J. Mocco, Jawaharlal M. Patel, Joseph Francis, Maria B. Grant, Michael J. Katovich, and Mohan K. Raizada
Submissions from 2011
Plasma carboxypeptidase B downregulates inflammatory responses in autoimmune arthritis, Jason J. Song, Inyong Hwang, Kyung H. Cho, Michael A. Garcia, Arthur J. Kim, Tiffany H. Wang, Tamsin M. Lindstrom, Annette T. Lee, Toshihiko Nishimura, Lei Zhao, John Morser, Michael Nesheim, Stuart B. Goodman, David M. Lee, S. Louis Bridges, Peter K. Gregersen, Lawrence L. Leung, and William H. Robinson