Estimation of fusiform intracranial aneurysm growth by serial magnetic resonance imaging

Authors

Bradley P. Dispensa, University of California, San Francisco
David A. Saloner, University of California, San Francisco
Gabriel Acevedo-Bolton, University of California, San FranciscoFollow
Achal S. Achrol, University of California, San FranciscoFollow
Lianger Der Jou, University of California, San Francisco
Charles E. McCulloch, University of California, San Francisco
S. Claiborne Johnston, University of California, San Francisco
Randall T. Higashida, University of California, San Francisco
Christopher F. Dowd, University of California, San Francisco
V. Van Halbach, University of California, San Francisco
Nerissa U. Ko, University of California, San Francisco
Michael T. Lawton, University of California, San FranciscoFollow
Alastair J. Martin, University of California, San Francisco
Nancy Quinnine, University of California, San Francisco
William L. Young, University of California, San Francisco

Document Type

Article

Abstract

Purpose: Intracranial aneurysm (IA) growth is associated with increased morbidity. We sought to establish a quantitative computational method based on contrast-enhanced MR angiography (CE-MRA) for estimating aneurysmal volume changes over time. Materials and Methods: Computational volume calculations were tested against a distensible phantom. Untreated patients with IA were followed longitudinally with annual MRI. Maximal linear dimensions along the longitudinal axis and two transverse axes were determined by visual review of maximum intensity projection (MIP) data, and aneurysm volume was approximated as (length x width x height)/2. Averages of the visual approximations were compared to the lumenal volume as determined with a computational algorithm using the MRI data. Results: MRI-based measurements accurately represented volume changes in the phantom (R2 = 0.97, Y = 1.06x + 271 CM3). In the clinical study there were a total of 11 intervals of one-year follow-up in six patients (mean ± SD, age = 53 ± 20 years). The raw one-year growth using the computational volume was 9% ± 17%. The corresponding value for the averaged measurement of the reviewers was 8% ± 14%. Neither the mean values nor the SDs were different (P = .51). Conclusion: MRI-based measurement of aneurysm volume appears feasible for longitudinal studies of aneurysm natural history. © 2007 Wiley-Liss, Inc.

Publication Date

7-1-2007

Publication Title

Journal of Magnetic Resonance Imaging

ISSN

10531807

E-ISSN

15222586

Volume

26

Issue

1

First Page

177

Last Page

183

PubMed ID

17659544

Digital Object Identifier (DOI)

10.1002/jmri.20944

Recommended Citation

Dispensa, Bradley P.; Saloner, David A.; Acevedo-Bolton, Gabriel; Achrol, Achal S.; Jou, Lianger Der; McCulloch, Charles E.; Johnston, S. Claiborne; Higashida, Randall T.; Dowd, Christopher F.; Halbach, V. Van; Ko, Nerissa U.; Lawton, Michael T.; Martin, Alastair J.; Quinnine, Nancy; and Young, William L., "Estimation of fusiform intracranial aneurysm growth by serial magnetic resonance imaging" (2007). Neurosurgery. 949.
https://scholar.barrowneuro.org/neurosurgery/949