Mechanical thrombectomy - is time still brain? The DAWN of a new era

Authors

Naveed Kamal, Department of Neurosurgery , Rutgers University, New Jersey Medical School , Newark , NJ , USA.
Neil Majmundar, Department of Neurosurgery , Rutgers University, New Jersey Medical School , Newark , NJ , USA.Follow
Nitesh Damadora, Department of Neurosurgery , Rutgers University, New Jersey Medical School , Newark , NJ , USA.
Mohammad El-Ghanem, Department of Neurosurgery , Rutgers University, New Jersey Medical School , Newark , NJ , USA.
Rolla Nuoman, Department of Neurology , Rutgers University, New Jersey Medical School , Newark , NJ , USA.
Irwin A. Keller, Department of Radiology , Rutgers University, Robert Wood Johnson Medical School , New Brunswick , NJ , USA.
Steven Schonfeld, Department of Radiology , Rutgers University, Robert Wood Johnson Medical School , New Brunswick , NJ , USA.
Igor Rybinnik, Department of Neurology , Rutgers University, Robert Wood Johnson Medical School , New Brunswick , NJ , USA.
Gaurav Gupta, Department of Neurosurgery , Rutgers University, Robert Wood Johnson Medical School , New Brunswick , NJ , USA.
Sudipta Roychowdry, Department of Radiology , Rutgers University, Robert Wood Johnson Medical School , New Brunswick , NJ , USA.
Fawaz Al-Mufti, Department of Neurosurgery , Rutgers University, New Jersey Medical School , Newark , NJ , USA.

Document Type

Article

Abstract

PURPOSE: The purpose of this study is to review the history of treatments for acute ischemic stroke, examine developments in endovascular therapy, and discuss the future of the management of acute ischemic stroke. METHODS: A selective review of recent clinical trials for the treatment of acute ischemic stroke was conducted. RESULTS: We reviewed completed trials of the management of acute ischemic stroke including intravenous thrombolytics, intraarterial thrombolytics, and thrombectomy. We also assessed the future direction of research by reviewing ongoing clinical trials. CONCLUSIONS: The advancement of endovascular treatment for stroke has led to improved morbidity and mortality for patients. Future challenges include delivering these treatments to stroke centers worldwide.

Medical Subject Headings

Acute Disease; Brain Ischemia (epidemiology, therapy); Clinical Trials as Topic; Cross-Sectional Studies; Endovascular Procedures (methods); Female; Fibrinolytic Agents (therapeutic use); Humans; Intracranial Thrombosis (epidemiology, therapy); Male; Thrombectomy (methods); Tissue Plasminogen Activator (therapeutic use); Treatment Outcome

Publication Date

6-1-2018

Publication Title

British journal of neurosurgery

E-ISSN

1360-046X

Volume

32

Issue

3

First Page

245

Last Page

249

PubMed ID

29417839

Digital Object Identifier (DOI)

10.1080/02688697.2018.1426726

Recommended Citation

Kamal, Naveed; Majmundar, Neil; Damadora, Nitesh; El-Ghanem, Mohammad; Nuoman, Rolla; Keller, Irwin A.; Schonfeld, Steven; Rybinnik, Igor; Gupta, Gaurav; Roychowdry, Sudipta; and Al-Mufti, Fawaz, "Mechanical thrombectomy - is time still brain? The DAWN of a new era" (2018). Neurosurgery. 2213.
https://scholar.barrowneuro.org/neurosurgery/2213