Immunotherapeutic Approaches for Glioblastoma Treatment

Authors

Nasser K. Yaghi, Neuro-Oncology Branch, CCR, NCI, National Institutes of Health, Bethesda, MD 20892, USA.
Mark R. Gilbert, Neuro-Oncology Branch, CCR, NCI, National Institutes of Health, Bethesda, MD 20892, USA.

Document Type

Article

Abstract

Glioblastoma remains a challenging disease to treat, despite well-established standard-of-care treatments, with a median survival consistently of less than 2 years. In this review, we delineate the unique disease-specific challenges for immunotherapies, both brain-related and non-brain-related, which will need to be adequately overcome for the development of effective treatments. We also review current immunotherapy treatments, with a focus on clinical applications, and propose future directions for the field of GBM immunotherapy.

Publication Date

2-11-2022

Publication Title

Biomedicines

ISSN

2227-9059

Volume

10

Issue

2

PubMed ID

35203636

Digital Object Identifier (DOI)

10.3390/biomedicines10020427

Recommended Citation

Yaghi, Nasser K. and Gilbert, Mark R., "Immunotherapeutic Approaches for Glioblastoma Treatment" (2022). Neurosurgery. 1924.
https://scholar.barrowneuro.org/neurosurgery/1924