Multifocal dysembryoplastic neuroepithelial tumours associated with refractory epilepsy
Dysembryoplastic neuroepithelial tumours (DNET) are a common cause of tumour-associated epilepsy, and are usually located in the temporal lobes. We present a case of multifocal DNETs in both infra- and supra-tentorial locations, in a 23-year-old man with a coincident Type I Chiari malformation, presenting with medically refractory focal seizures. The extensive anatomical distribution of the lesions suggests a genetic component in their tumourigenesis.
Medical Subject Headings
Brain Neoplasms (complications, pathology); Epilepsy (etiology, pathology); Humans; Male; Neoplasms, Neuroepithelial (complications, pathology); Seizures (etiology, pathology); Temporal Lobe (pathology); Young Adult
Epileptic disorders : international epilepsy journal with videotape
Digital Object Identifier (DOI)
Yang, Andrew I.; Khawaja, Ayaz M.; Ballester-Fuentes, Leo; Pack, Svetlana D.; Abdullaev, Ziedulla; Patronas, Nicholas J.; Inati, Sara K.; Theodore, William H.; Quezado, Martha M.; and Zaghloul, Kareem A., "Multifocal dysembryoplastic neuroepithelial tumours associated with refractory epilepsy" (2014). Neurosurgery. 1877.