A Retrospective Analysis of the L3-L4 Disc and Spinopelvic Parameters on Outcomes in Thoracolumbar Fusion: Was Art Steffee Right?

Mark M. Kodsy, Center for Spine Health, Neurological Institute, Cleveland Clinic, Cleveland, Ohio, USA; College of Medicine, Northeast Ohio Medical University, Rootstown, Ohio, USA. Electronic address: mkodsy@neomed.edu.
Harvey E. Freitag, Center for Spine Health, Neurological Institute, Cleveland Clinic, Cleveland, Ohio, USA; School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.
Robert D. Winkelman, Center for Spine Health, Neurological Institute, Cleveland Clinic, Cleveland, Ohio, USA; School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.
Nicholas M. Rabah, Center for Spine Health, Neurological Institute, Cleveland Clinic, Cleveland, Ohio, USA; School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.
Bryan S. Lee, Center for Spine Health, Neurological Institute, Cleveland Clinic, Cleveland, Ohio, USA; Department of Neurosurgery, Barrow Neurological Institute, Phoenix, Arizona, USA.Follow
Ryan Honomichl, Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio, USA.
Nicolas Thompson, Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio, USA.
Jason W. Savage, Center for Spine Health, Neurological Institute, Cleveland Clinic, Cleveland, Ohio, USA.
R Douglas Orr, Center for Spine Health, Neurological Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Edward C. Benzel, Center for Spine Health, Neurological Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Iain H. Kalfas, Center for Spine Health, Neurological Institute, Cleveland Clinic, Cleveland, Ohio, USA.

Document Type

Article

Abstract

OBJECTIVE: To determine whether the L3-L4 disc angle may be a surrogate marker for global lumbar alignment in thoracolumbar fusion surgery and to explore the relationship between radiographic and patient-reported outcomes after thoracolumbar fusion surgery. METHODS: Retrospective chart review was conducted on patients who had undergone a lumbar fusion involving levels from T9 to pelvis. EuroQol-Five Dimension (EQ-5D-3L) scores and adverse events including adjacent-segment disease and degeneration, pseudoarthrosis, proximal junctional kyphosis, stenosis, and reoperation were collected. Pre- and postoperative spinopelvic parameters were measured on weight-bearing radiographs, with the L3-L4 disc angle of novel interest. Univariate logistic and linear regression were performed to assess the associations of radiographic parameters with adverse event incidence and improvement in EQ-5D-3L, respectively. RESULTS: In total, 182 patients met inclusion criteria. Univariable analysis revealed that increased magnitude of L3-L4 disc angle, anterior pelvic tilt, and pelvic incidence measures are associated with increased likelihood of developing postoperative adverse events. Conversely, increased lumbar lordosis demonstrated a decreased incidence of developing a postoperative adverse event. Linear regression showed that radiographic parameters did not significantly correlate with postoperative EQ-5D-3L scores, although scores were significantly improved postfusion in all dimensions except Self-Care (P = 0.51). CONCLUSIONS: L3-L4 disc angle magnitude may serve as a surrogate marker of global lumbar alignment. The degree of spinopelvic alignment did not correlate to improvement in EQ-5D-3L score in the present study, suggesting that quality of life metric change may not be a sensitive or specific marker of postfusion alignment.

Medical Subject Headings

Humans; Lordosis (surgery); Lumbar Vertebrae (diagnostic imaging, surgery); Quality of Life; Retrospective Studies; Spinal Fusion (methods)

Publication Date

3-1-2022

Publication Title

World neurosurgery

E-ISSN

1878-8769

Volume

159

First Page

e399

Last Page

e406

PubMed ID

34954442

Digital Object Identifier (DOI)

10.1016/j.wneu.2021.12.065

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