A two-stage combined anterolateral and endoscopic endonasal approach to the petroclival region: an anatomical study and clinical application

Authors

Mohamed A. Labib, Department of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ, USA.Follow
Xiaochun Zhao, Department of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ, USA.
Lena Mary Houlihan, Department of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ, USA.
Irakliy Abramov, Department of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ, USA.Follow
Mizuho Inoue, Department of Neurosurgery, University of Colorado, Denver, CO, USA.
Rafael Martinez-Perez, Department of Neurosurgery, University of Colorado, Denver, CO, USA.
Joshua S. Catapano, Department of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ, USA.Follow
Michael T. Lawton, Department of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ, USA.Follow
Mark C. Preul, Department of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ, USA.
A Samy Youssef, Department of Neurosurgery, University of Colorado, Denver, CO, USA. samy.youssef@cuanschutz.edu.

Document Type

Article

Abstract

OBJECT: The pretemporal transcavernous anterior petrosal (PTAP) approach and the combined petrosal (CP) approach have been used to resect petroclival meningiomas (PCMs). In this cadaveric anatomical study, a two-stage combined PTAP and endoscopic endonasal far medial (EEFM) approach (the PTAPE approach) was compared morphometrically to the CP approach. A case study provides a clinical example of using the PTAPE approach to treat a patient with a PCM. The key elements of the approach selection process are outlined. METHODS: Five cadaveric specimens underwent a CP approach and 5 underwent a PTAPE approach. The area of drilled clivus, length of multiple cranial nerves (CNs), and the area of brain stem exposure were measured, reported as means (standard deviations) by group, and compared. RESULTS: The total area of the clivus drilled in the PTAPE group (695.3 [121.7] mm) was greater than in the CP group (88.7 [17.06] mm, P < 0.01). Longer segments of CN VI were exposed via the PTAPE than the CP approach (35.6 [9.07] vs. 16.3 [6.02] mm, P < 0.01). CN XII (8.8 [1.06] mm) was exposed only in the PTAPE group. Above the pontomedullary sulcus, the total area of brain stem exposed was greater with the PTAPE than the CP approach (1003.4 [219.5] mm vs. 437.6 [83.7] mm, P < 0.01). Similarly, the total exposure of the medulla was greater after the PTAPE than the CP exposure (240.2 [57.06] mm vs. 48.1 [19.9] mm, P < 0.01). CONCLUSION: A combined open-endoscopic paradigm is proposed for managing large PCMs. This approach incorporates the EEFM approach to address the limitations of the PTAP and the CP approach in a systematic fashion. Understanding the anatomical findings of this study will aid in tailoring surgical approaches to patients with these complex lesions.

Medical Subject Headings

Cadaver; Cranial Fossa, Posterior (anatomy & histology, surgery); Humans; Meningeal Neoplasms (surgery); Meningioma (surgery); Neurosurgical Procedures; Petrous Bone (surgery); Skull Base Neoplasms (surgery)

Publication Date

7-1-2022

Publication Title

Acta neurochirurgica

E-ISSN

0942-0940

Volume

164

Issue

7

First Page

1899

Last Page

1910

PubMed ID

35416540

Digital Object Identifier (DOI)

10.1007/s00701-022-05201-1

Recommended Citation

Labib, Mohamed A.; Zhao, Xiaochun; Houlihan, Lena Mary; Abramov, Irakliy; Inoue, Mizuho; Martinez-Perez, Rafael; Catapano, Joshua S.; Lawton, Michael T.; Preul, Mark C.; and Youssef, A Samy, "A two-stage combined anterolateral and endoscopic endonasal approach to the petroclival region: an anatomical study and clinical application" (2022). Neurosurgery. 1558.
https://scholar.barrowneuro.org/neurosurgery/1558