Endoscopic Intraventricular Biopsy of Infundibular Langerhans Cell Histiocytosis: Case Report
OBJECTIVE: Surgical biopsy of isolated infundibular lesions is indicated in patients who are symptomatic or whose imaging suggests a treatable lesion. Early therapy can prevent irreversible neurological or endocrinological damage and, potentially, metastasis. These considerations justify the small risk associated with surgery. CLINICAL PRESENTATION: A 5-year-old boy presented with diabetes insipidus and an enhancing lesion of the pituitary stalk without evidence of extracranial disease. INTERVENTION: The lesion was biopsied via an endoscopic intraventricular approach without complications. Pathological examination revealed Langerhans cell histiocytosis. CONCLUSION: Endoscopic intraventricular biopsy can be considered as a less invasive alternative to craniotomy in patients with infundibular lesions protruding superiorly into the third ventricle. Copyright Â© by the Congress of Neurological Surgeons.
Digital Object Identifier (DOI)
Killory, Brendan D.; Ponce, Francisco A.; Wait, Scott D.; Coons, Stephen W.; and Rekate, Harold L., "Endoscopic Intraventricular Biopsy of Infundibular Langerhans Cell Histiocytosis: Case Report" (2009). Neurosurgery. 150.