Ectomesenchymal Hamartoma (Benign "ectomesenchymoma") of the VIIIth Nerve: Case Report
WE REPORT A previously undescribed hamartoma of the VIIIth nerve, consisting of adipose tissue, Schwann cells associated with myelinated nerve fibers, well-differentiated smooth and striated muscle fibers, and rare ganglion cells. The tumor was found in a 35-year-old Caucasian female who presented with right-sided hearing loss. The mass, which we designate an â€œectomesenchymalâ€ hamartoma, most likely developed from pluripotent neural crest cells (â€œectomesenchymeâ€), which are capable of differentiating into a variety of neuroectodermal and mesenchymal cell types. The development of the neural crest, the concept of â€œectomesenchyme,â€ and the histogenesis of this tumor are reviewed. Copyright Â© by the Congress of Neurological Surgeons.
Digital Object Identifier (DOI)
Apostolides, Paul J.; Spetzler, Robert F.; and Johnson, Peter C., "Ectomesenchymal Hamartoma (Benign "ectomesenchymoma") of the VIIIth Nerve: Case Report" (1995). Neurosurgery. 140.