Epilepsy, antiseizure therapy, and sleep cycle parameters
Document Type
Article
Abstract
A reciprocal relationship exists between sleep and epilepsy. The quality of sleep is affected by the presence and frequency of seizures, type of antiepileptic therapy utilized, and coexisting primary sleep disorders. Daytime somnolence is one of the most common adverse effects of antiepileptic therapy, with specific pharmacologic agents exhibiting a unique influence on components of sleep architecture. The newer generation of antiseizure drugs demonstrates improved sleep efficiency, greater stabilization of sleep architecture, prolongation of REM sleep duration, and increased quality of life measures. The emerging field of chronoepileptology explores the relationship between seizures and circadian rhythms, aiming for targeted use of antiseizure therapies to maximize therapeutic effects and minimize the adverse events experienced by the patients.
Publication Date
9-3-2013
Publication Title
Epilepsy research and treatment
ISSN
2090-1348
Volume
2013
First Page
670682
PubMed ID
23997949
Digital Object Identifier (DOI)
10.1155/2013/670682
Recommended Citation
Shvarts, Vladimir and Chung, Steve, "Epilepsy, antiseizure therapy, and sleep cycle parameters" (2013). Neurology. 718.
https://scholar.barrowneuro.org/neurology/718