Auditory Mapping With MEG: An Update on the Current State of Clinical Research and Practice With Considerations for Clinical Practice Guidelines

Document Type

Article

Abstract

Auditory evoked fields (AEFs) are well suited for studies of auditory processing in patients. Their sources have been localized to Heschl's gyri and to the supratemporal auditory cortices. Auditory evoked fields are known to be modulated by peripheral and central lesions of auditory pathways and to reflect group-level pathophysiology of neurodevelopmental and psychiatric disorders. They are useful in lateralization of language processes for planning neurosurgery and for localization of language-related cortex. The recently developed artifact rejection and movement compensation methods will enhance and extend the use of AEFs in studies of clinical patients and pediatric groups. New pediatric magnetoencephalography systems will facilitate clinical AEF studies of developmental disorders. In addition to their established use in planning neurosurgery, AEF findings in several new clinical patient groups suffering, e.g., from developmental, neurodegenerative, or psychiatric disorders have been reported. Several recent investigations report the correlations with clinical symptoms and sensitivity and specificity profiles of AEFs in studies of these disorders; this development is mandatory in gaining wider clinical approval for the use of AEFs in clinical practice dealing with individual patients. Most promising future research lines of clinical applicability of AEFs focus on developmental and psychiatric disorders.

Medical Subject Headings

Acoustic Stimulation (methods, standards); Auditory Cortex (diagnostic imaging, physiology); Auditory Perception (physiology); Biomedical Research (methods, standards); Brain Mapping (methods, standards); Developmental Disabilities (diagnostic imaging, physiopathology); Evoked Potentials, Auditory (physiology); Humans; Magnetoencephalography (methods, standards); Practice Guidelines as Topic (standards)

Publication Date

11-10-2020

Publication Title

Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society

E-ISSN

1537-1603

Volume

37

Issue

6

First Page

574

Last Page

584

PubMed ID

33165230

Digital Object Identifier (DOI)

10.1097/WNP.0000000000000518

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