Isolated amyloidosis presenting with lumbosacral radiculoplexopathy: Description of two cases and pathogenic review

Document Type

Article

Abstract

In this study, we present two cases of infiltrative, localized amyloidosis involving lumbosacral root and plexus, e.g., isolated amyloidomas. Rare and poorly understood amyloidomas may occur in both neurologic and non-neurologic tissues. The described cases emphasize potential for localized peripheral amyloidomas: (1) potential for associated λ light chain lymphoplasmacytic lymphoma association; (2) e isolated amyloidosis without evidence for systemic plasma cell dyscrasia; (3) features suggestive of potential pathogenesis; and (4) discussion of treatment options including immunotherapy and resection. The limited literature and experience among other cases is described. © 2006 Peripheral Nerve Society.

Publication Date

12-1-2006

Publication Title

Journal of the Peripheral Nervous System

ISSN

10859489

E-ISSN

15298027

Volume

11

Issue

4

First Page

346

Last Page

352

PubMed ID

17117943

Digital Object Identifier (DOI)

10.1111/j.1529-8027.2006.00107.x

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